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YOSHIDA Masashi  吉田 賢司

ORCIDConnect your ORCID iD *help
Researcher Number 70532761
Other IDs
Affiliation (based on the past Project Information) *help 2021 – 2022: 岡山大学, 医歯薬学域, 講師
2016 – 2020: 岡山大学, 医歯薬学総合研究科, 講師
2011 – 2015: 岡山大学, 医歯(薬)学総合研究科, 助教
2014: 岡山大学, 医歯薬学総合研究科, 助教
2012: 岡山大学, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field
Principal Investigator
Cardiovascular medicine / Circulatory organs internal medicine
Except Principal Investigator
Cardiovascular medicine / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related / Basic Section 55030:Cardiovascular surgery-related
Keywords
Principal Investigator
DNAマイクロアレイ / 心臓内幹細胞 / 内皮細胞 / 分子生物学 / DNA マイクロアレイ / 老化
Except Principal Investigator
腹部大動脈瘤 / 肺動脈性肺高血圧症 / 肺移植 / エネルギー代謝 … More / 特発性肺動脈性肺高血圧症 / 細胞外マトリックス / インテグリン / 肺高血圧治療薬 / 乳酸脱水素酵素 / ピルビン酸脱水素酵素キナーゼ / ピルビン酸脱水素酵素 / 肺高血圧症 / 解糖系 / ミトコンドリア代謝 / ミトコンドリア呼吸 / 糖代謝 / 肺動脈平滑筋細胞 / マイクロアレイ / 線維芽細胞 / 血管平滑筋細胞 / α1インテグリン / 胸部大動脈解離 / アンジオテンシン / 大動脈解離 / Warburg効果 / 心筋細胞 / iPS細胞 / extracellular matrix / integrin / 接着因子 / 急性腎障害 / 虚血性プレコンディショニング / exosome / acute kidney injury / ischemic preconditioning / マイクロRNA / エクソソーム / プレコンディショニング / 造影剤腎症 / 虚血プレコンディショニング / 心臓突然死 / 電流活性化因子 / KCNH2 / 血液 / サブクローニング / QT短縮症候群 / 自己免疫 / HEK293細胞 / QT延長症候群 / イオンチャネル / 心不全 / HERG電流 / 心室性不整脈 / ヒアルロン酸 / サイトカイン / 動脈硬化 / 炎症性遺伝子 / CD44 Less
  • Research Projects

    (9 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (11 People)
  •  Energy metabolism of idiopathic pulmonary arterial hypertension

    • Principal Investigator
      Akagi Satoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Okayama University
  •  Impact of integrin on the development of aortic dissection

    • Principal Investigator
      MIYOSHI Toru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  Characteristics of cardiomyocyte from idiopathic pulmonary arterial hypertension and newly developed treatment

    • Principal Investigator
      Akagi Satoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Okayama University
  •  The role of remote ischemic preconditioning in contrast induced nephropathy

    • Principal Investigator
      ITO Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Okayama University
  •  The role of integrin in the development of abdominal aortic aneurysm

    • Principal Investigator
      MIYOSHI Toru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Okayama University
  •  Clarification of the mechanism how human cardiac progenitor cells differentiate into cardiomyocytes.Principal Investigator

    • Principal Investigator
      YOSHIDA Masashi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Okayama University
  •  The evaluation of CD44 in pathogenesis of abdominal aortic aneurysm and the development of new therapy

    • Principal Investigator
      MIYOSHI Toru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Okayama University
  •  Identification and Effects of KCNH2 (HERG) current-activating factor

    • Principal Investigator
      NAKAMURA Kazufumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Okayama University
  •  Comprehensive analysis of the changesin role of cardiac progenitor cells during agingPrincipal Investigator

    • Principal Investigator
      YOSHIDA Masashi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Okayama University

All 2021 2020 2019 2014 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Efficacy of shear wave elastography for evaluating right ventricular myocardial fibrosis in monocrotaline-induced pulmonary hypertension rats2021

    • Author(s)
      Nakayama Rie、Takaya Yoichi、Nakamura Kazufumi、Kondo Megumi、Kobayashi Kaoru、Ohno Yuko、Amioka Naofumi、Akagi Satoshi、Yoshida Masashi、Miyoshi Toru、Ito Hiroshi
    • Journal Title

      Journal of Cardiology

      Volume: in press Issue: 1 Pages: 17-23

    • DOI

      10.1016/j.jjcc.2021.01.015

    • NAID

      120007189478

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-20K08424, KAKENHI-PROJECT-21K08108
  • [Journal Article] Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats2020

    • Author(s)
      Nakamura Kazufumi、Akagi Satoshi、Ejiri Kentaro、Yoshida Masashi、Miyoshi Toru、Sakaguchi Masakiyo、Amioka Naofumi、Suastika Luh Oliva Saraswati、Kondo Megumi、Nakayama Rie、Takaya Yoichi、Higashimoto Yuichiro、Fukami Kei、Matsubara Hiromi、Ito Hiroshi
    • Journal Title

      Journal of Cardiology

      Volume: - Issue: 1 Pages: 12-16

    • DOI

      10.1016/j.jjcc.2020.12.009

    • NAID

      120007182876

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K08424, KAKENHI-PROJECT-21K08108
  • [Journal Article] Deficiency of CD44 prevents thoracic aortic dissection in a murine model.2020

    • Author(s)
      Hatipoglu OF, Miyoshi T, Yonezawa T, Kondo M, Amioka N, Yoshida M, Akagi S, Nakamura K, Hirohata S, Ito H.
    • Journal Title

      Sci Rep

      Volume: 10 Issue: 1 Pages: 6869-6869

    • DOI

      10.1038/s41598-020-63824-9

    • NAID

      120006883500

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04313, KAKENHI-PROJECT-17K11009, KAKENHI-PROJECT-18K08758, KAKENHI-PROJECT-20H00548
  • [Journal Article] Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats.2019

    • Author(s)
      Miyoshi T, Nakamura K, Miura D, Yoshida M, Saito Y, Akagi S, Ohno Y, Kondo M, Ito H.
    • Journal Title

      Cardiol J.

      Volume: 26(5) Issue: 5 Pages: 575-583

    • DOI

      10.5603/cj.a2018.0048

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08758
  • [Journal Article] Emerging Role of Coronary Computed Tomography Angiography in Lipid-Lowering Therapy: a Bridge to Image-Guided Personalized Medicine.2019

    • Author(s)
      Miyoshi T, Osawa K, Ichikawa K, Suruga K, Miki T, Yoshida M, Nakagawa K, Toda H, Nakamura K, Morita H, Ito H.
    • Journal Title

      Curr Cardiol Rep.

      Volume: 21(8) Issue: 8 Pages: 72-72

    • DOI

      10.1007/s11886-019-1170-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08758
  • [Journal Article] Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension2019

    • Author(s)
      Nakamura Kazufumi、Akagi Satoshi、Ejiri Kentaro、Yoshida Masashi、Miyoshi Toru、Toh Norihisa、Nakagawa Koji、Takaya Yoichi、Matsubara Hiromi、Ito Hiroshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 23 Pages: 5885-5885

    • DOI

      10.3390/ijms20235885

    • NAID

      120006816633

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-17K09498
  • [Journal Article] Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome2014

    • Author(s)
      Junko Kobayashi, Masashi Yoshida, Suguru Tarui, Masataka Hirata, Yusuke Nagai, Shingo Kasahara, Kenji Naruse, Hiroshi Ito, Shunji Sano, Hidemasa Oh
    • Journal Title

      PLOS one

      Volume: 9

    • NAID

      120005553911

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860603
  • [Journal Article] Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in rats2014

    • Author(s)
      Miyoshi T, Nakamura K, Yoshida M, Miura D, Oe H, Akagi S, Sugiyama H, Akazawa K, Yonezawa T, Wada J, Ito H
    • Journal Title

      Cardiovasc Diabetol

      Volume: 13 Issue: 1 Pages: 43-43

    • DOI

      10.1186/1475-2840-13-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591053, KAKENHI-PROJECT-25860603
  • [Journal Article] Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice2011

    • Author(s)
      Ikeda H, Shiojima I, Oka T, Yoshida M, Maemura K, Walsh K, Igarashi T, Komuro I
    • Journal Title

      Mol Cell Biol

      Volume: 31(5) Issue: 5 Pages: 1054-65

    • DOI

      10.1128/mcb.00732-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Journal Article] Intermittent arm ischemia induces vasodilatation of the contralateral upper limb2011

    • Author(s)
      Kenki Enko, Kazufumi Nakamura, Kei Yunoki, Toru Miyoshi, Satoshi Akagi, Masashi Yoshida, Norihia Toh, Mutsuko Sangawa, Nobuhiro Nishii, Satoshi Nagase, Kunihisa Kohno, Hiroshi Morita, Kengo F. Kusano, Hiroshi Ito
    • Journal Title

      J Physiol Sci

      Volume: 61(6) Issue: 6 Pages: 507-13

    • DOI

      10.1007/s12576-011-0172-9

    • NAID

      10030351098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Journal Article] Prostaglandin I(2) induces apoptosis via upregulation of Fas ligand in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension2011

    • Author(s)
      Akagi S, Nakamura K, Matsubara H, Fukushima Kusano K, Kataoka N, Oto T, Miyaji K, Miura A, Ogawa A, Yoshida M, Ueda-Ishibashi H, Yutani C, Ito H
    • Journal Title

      Int J Cardiol

      Volume: in press Issue: 3 Pages: 499-505

    • DOI

      10.1016/j.ijcard.2011.09.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790855, KAKENHI-PROJECT-25860632
  • [Presentation] Higher Oxidized HDL is Associated with High-risk Plaques Determined by CT Angiography in Patients with Suspected with Coronary Artery Disease2020

    • Author(s)
      Kazuki Suruga, Toru Miyoshi, Kazuhiko Kotani, Takashi Miki, Keishi Ichikawa, Kazuhiro Osawa, Hiroaki Otsuka, Masatoki Yoshida, Kazufumi Nakamura, Hiroshi Itoh
    • Organizer
      第84回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08758
  • [Presentation] Pemafibrate Reduces the Rupture of Experimental Aortic Aneurysm by Inhibiting Oxidative Stress2020

    • Author(s)
      Naofumi Amioka, Toru Miyoshi, Tomonari Kimura, Satoshi Akagi, Masashi Yoshida, Kazufumi Nakamura, Hiroshi Morita, Hiroshi Itoh
    • Organizer
      第84回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08758
  • [Presentation] Deficiency of Integrin Alpha1 Prevents Abdominal Aortic Aneurysm Rupture in Mice2019

    • Author(s)
      Toru Miyoshi 、Kazufumi Nakamura 、Masashi Yoshida 、Satoshi Akagi 、Tomonari Kimura 、Naofumi Amioka 、Hiroshi Itoh
    • Organizer
      第 83 回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08758
  • [Presentation] CD44 is Associated with the Development of Thoracic Aortic Aneurysm and Dissection in Mice2019

    • Author(s)
      Toru Miyoshi 、Kazufumi Nakamura 、Masashi Yoshida 、Satoshi Akagi 、Tomonari Kimura 、Naofumi Amioka 、Hiroshi Itoh
    • Organizer
      第 83 回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08758
  • [Presentation] Transition in cardiogenic to angiogenic potential of human cardiac progenitor cells occurs with age2012

    • Author(s)
      吉田賢司
    • Organizer
      ISSCR 2012
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-13
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Presentation] Hedgehog interacting proteicontrols age-dependent angiogenic activity in human cardiac progenitor cells through insulin-like growth factor-1 receptor signaling2012

    • Author(s)
      吉田賢司
    • Organizer
      American Heart Association Scientific Session 2012
    • Place of Presentation
      ロサンゼルスn 、カリフォルニア州、アメリカ合衆国
    • Year and Date
      2012-11-03
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Presentation] Both insulin-like growth factor-1 and -2 receptor control human cardiac progenitor proliferation adifferentiation in children with congenital heart malformation2011

    • Author(s)
      吉田賢司
    • Organizer
      2011米国心臓協会学術集nd 会
    • Place of Presentation
      米国、オーランド
    • Year and Date
      2011-11-15
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Presentation] Both insulin-like growth factor-1 and -2 receptor control human cardiac progenitor proliferation and differentiation in children with congenital heart malformation2011

    • Author(s)
      吉田賢司
    • Organizer
      2011米国心臓協会学術集会
    • Place of Presentation
      米国、オーランド
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Presentation] Hedgehog interacting protein controls age-dependent angiogenic activity in human cardiac progenitor cells through insulin-like growth factor-1 receptor signaling

    • Author(s)
      Masashi Yoshida
    • Organizer
      American Heart Association Scientific Session 2012
    • Place of Presentation
      ロサンゼルス, カリフォルニア州, アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-23790855
  • [Presentation] Inhibition of DPP-4 attenuates monocyte inflammatory response through suppression of MAPK phosphorylation and ameliorates the development of CaCl2-induced abdominal aortic aneurysm in mice

    • Author(s)
      Y. Noda, T. Miyoshi, T. Yonezawa, M. Yoshida, K. Kohno, K. Nakamura, H. Morita, H. Ito
    • Organizer
      ESC CONGRESS 2014
    • Place of Presentation
      BARCELONA
    • Year and Date
      2014-08-30 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-24591053
  • [Presentation] Genetic Deletion of Integrin Alpha1beta1 Alleviates Aortic Rupture in Angiotensin II-induced Abdominal Aortic Aneurysm

    • Author(s)
      T. Miyoshi, T. Yonezawa, M. Yoshida, S. Akagi, Y. Saito, K. Nakamura, H. Ito
    • Organizer
      AHA scientific session 2014
    • Place of Presentation
      Chicago
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-24591053
  • [Presentation] T-box 5 controls age-dependent cardiogenic activity in human cardiac progenitor cells through insulin-like growth factor-1 receptor signaling

    • Author(s)
      Masashi Yoshida, Suguru Tarui, Junko Kobayashi, Toru Miyoshi, Youhei Maeshima, Shunji Sano, Hiroshi Ito, Hidemasa Oh
    • Organizer
      ESC2014
    • Place of Presentation
      バルセロナ
    • Year and Date
      2014-08-30 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-25860603
  • [Presentation] Transition in cardiogenic to angiogenic potential of human cardiac progenitor cells occurs with age

    • Author(s)
      Masashi Yoshida
    • Organizer
      ISSCR 2012
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23790855
  • 1.  NAKAMURA Kazufumi (10335630)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 11 results
  • 2.  ITO Hiroshi (90446047)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 8 results
  • 3.  MIYOSHI Toru (70444651)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 4.  YONEZAWA Tomoko (30304299)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  Akagi Satoshi (60601127)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  MORITA Hiroshi (50322227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MARUYAMA Toru (90423657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  斎藤 幸弘 (20724454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  白井 朋子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 10.  深水 圭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  廣畑 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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