IWAMOTO Noriyuki 岩本紀之

Researcher Number	70534709
Affiliation (based on the past Project Information) *help	2013: 独立行政法人国立循環器病研究センター, 研究所, 客員研究員 2012: 独立行政法人国立循環器病研究センター, 研究所, 派遣研究員 2011: 独立行政法人国立循環器病研究センター, 糖尿病・代謝内科, 医師 2009 – 2010: Nagoya City University, 大学院・医学研究科, 研究員
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator HDL / ABCA1 / 核酸医薬 / 動脈硬化 / アポリポプロテイン / カルパイン / カルモジュリン / AP2 / PKC / コレステロール

Development of increasing functional HDL-C using antisense oligonucleotides as innovative therapyPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Noriyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
Development of HDL-raising drugs targeting ABCA1Principal Investigator
- Principal Investigator
  
  IWAMOTO Noriyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya City University

All 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Protein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2: a common pathway to the ABCA1 gene regulation2011
- Author(s)
  Iwamoto N, Yokoyama S
- Journal Title
  
  Atherosclerosis
  
  Volume: 216(1) Pages: 90-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591109
[Journal Article] Protein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2 ; a common pathway to the ABCA1 gene regulation.2011
- Author(s)
  Noriyuki Iwamoto, Shinji Yokoyama.
- Journal Title
  
  Atherosclr. 216
  
  Pages: 90-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] Calmodulin Interacts with ATP Binding Cassette Transporter A1 to Protect from Calpain-Mediated Degradation and Upregulates High Density Lipoprotein Generation.2010
- Author(s)
  Noriyuki Iwamoto, Rui Lu, Nobukiyo Tanaka, Sumiko Abe-dohmae, Shinji Yokoyama
- Journal Title
  
  Arteriosclr.Thromb.Vasc.Biol
  
  Volume: 30 Pages: 1446-1452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] Calmodulin Interacts with ATP Binding Cassette Transporter A1 to Protect from Calpain-Mediated Degradation and Upregulates High Density Lipoprotein Generation.2010
- Author(s)
  Noriyuki Iwamoto, Rui Lu, Nobukiyo Tanaka, Sumiko Abe-dohmae, Shinji Yokoyama
- Journal Title
  
  Arterioscler. Thromb.Vasc.Biol. 30
  
  Pages: 1446-1452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] Helical Apolipoproteins of High-Density Lipoprotein Enhance Phagocytosis by Stabilizing ATP-Binding Cassette Transporter A7.2010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama.
- Journal Title
  
  J.Lipid Res. 51
  
  Pages: 2591-2599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] Helical Apolipoproteins of High-Density Lipoprotein Enhance Phagocytosis by Stabilizing ATP-Binding Cassette Transporter A72010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Journal Title
  
  J.Lipid Research
  
  Volume: 51 Pages: 2591-2599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] FGF-1 induces expression of LXRalpha and production of 25-hydroxy cholesterol to up-regulate apoE gene transcription in rat astrocytes2009
- Author(s)
  呂鋭、岩本紀之, 他
- Journal Title
  
  The Journal of Lipid Research 50
  
  Pages: 1156-1164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] Pharmaoological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis2009
- Author(s)
  荒川礼二郎、岩本紀之, 他
- Journal Title
  
  The Journal of Lipid Research 50
  
  Pages: 2299-2305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Journal Article] Involvement of protein kinase D in phosphorylation and increase of DNA binding of activator protein 2 alpha to downregulate ATP-binding cassette transporter A12008
- Author(s)
  Iwamoto N, Abe-Dohmae S, Lu R, Yokoyama S
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 28(12) Pages: 2282-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591109
[Journal Article] ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2alpha. Doxazosin inhibits activator protein 2alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade2007
- Author(s)
  Iwamoto N, Abe-Dohmae S, Ayaori M, Tanaka N, Kusuhara M, Ohsuzu F, Yokoyama S
- Journal Title
  
  Circ Res
  
  Volume: 20;101(2) Pages: 156-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591109
[Journal Article] rotein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2 ; a common pathway to the ABCA1 gene regulation
- Author(s)
  Noriyuki Iwamoto, Shinji Yokoyama
- Journal Title
  
  Atheroscler.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790739
[Presentation] FHにおける妊娠とLDLアフェレシス2010
- Author(s)
  岩本紀之
- Organizer
  日本アフェレシス学会
- Place of Presentation
  東京
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-21790739
[Presentation] Regulation of ATP-Binding Cassette (ABC) tyansporter in Sterol Metabokism2010
- Author(s)
  岩本紀之
- Organizer
  日本動脈硬化学会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21790739
[Presentation] 転写調節因子AP2αによる細胞内脂質排出に関わる遺伝子調節機構2009
- Author(s)
  岩本紀之
- Organizer
  日本脂質生化学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-21790739
[Presentation] Calmodulin interacts with ABCA1 and regulate its expression level.2009
- Author(s)
  岩本紀之
- Organizer
  日本動脈硬化学会
- Place of Presentation
  山口
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-21790739

1. 斯波真理子 (70271575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWAMOTO Noriyuki 岩本 紀之

Research Projects

Research Products

Co-Researchers

Development of increasing functional HDL-C using antisense oligonucleotides as innovative therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of HDL-raising drugs targeting ABCA1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Protein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2: a common pathway to the ABCA1 gene regulation2011

Author(s)

Journal Title

Data Source

[Journal Article] Protein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2 ; a common pathway to the ABCA1 gene regulation.2011

Author(s)

Journal Title

Data Source

[Journal Article] Calmodulin Interacts with ATP Binding Cassette Transporter A1 to Protect from Calpain-Mediated Degradation and Upregulates High Density Lipoprotein Generation.2010

Author(s)

Journal Title

Data Source

[Journal Article] Calmodulin Interacts with ATP Binding Cassette Transporter A1 to Protect from Calpain-Mediated Degradation and Upregulates High Density Lipoprotein Generation.2010

Author(s)

Journal Title

Data Source

[Journal Article] Helical Apolipoproteins of High-Density Lipoprotein Enhance Phagocytosis by Stabilizing ATP-Binding Cassette Transporter A7.2010

Author(s)

Journal Title

Data Source

[Journal Article] Helical Apolipoproteins of High-Density Lipoprotein Enhance Phagocytosis by Stabilizing ATP-Binding Cassette Transporter A72010

Author(s)

Journal Title

Data Source

[Journal Article] FGF-1 induces expression of LXRalpha and production of 25-hydroxy cholesterol to up-regulate apoE gene transcription in rat astrocytes2009

Author(s)

Journal Title

Data Source

[Journal Article] Pharmaoological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis2009

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of protein kinase D in phosphorylation and increase of DNA binding of activator protein 2 alpha to downregulate ATP-binding cassette transporter A12008

Author(s)

Journal Title

Data Source

[Journal Article] ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2alpha. Doxazosin inhibits activator protein 2alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade2007

Author(s)

Journal Title

Data Source

[Journal Article] rotein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2 ; a common pathway to the ABCA1 gene regulation

Author(s)

Journal Title

Data Source

[Presentation] FHにおける妊娠とLDLアフェレシス2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Regulation of ATP-Binding Cassette (ABC) tyansporter in Sterol Metabokism2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 転写調節因子AP2αによる細胞内脂質排出に関わる遺伝子調節機構2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Calmodulin interacts with ABCA1 and regulate its expression level.2009

Author(s)

IWAMOTO Noriyuki 岩本紀之