Ishikawa Hiroshi 石川博士

… Alternative Names

ISHIKAWA Hiroshi 石川博士

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Researcher Number	70553973
Other IDs	https://orcid.org/0000-0003-1116-6885
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2024: 千葉大学, 大学院医学研究院, 講師 2020 – 2021: 千葉大学, 大学院医学研究院, 講師 2018 – 2019: 千葉大学, 大学院医学研究院, 助教 2016: 千葉大学, 医学部附属病院, 医員 2015: 千葉大学, 大学院医学研究院, 助教 … More 2012 – 2015: 千葉大学, 医学(系)研究科(研究院), 助教 2012: 千葉大学, 医学研究科(研究院), 助教 2011: 千葉大学, 大学院医学研究院, 助教 2009 – 2011: Chiba University, 大学院・医学研究院, 助教 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 子宮筋腫 / 低酸素 / HIF1 / 重症免疫不全マウス / xenograft / 移植モデル / 免疫不全マウス / クエン酸回路 / びまん性子宮平滑筋腫症 / フマル酸ヒドラターゼ … More / 血管新生 / xenograftモデル / VEGF / 子宮筋 / 低酸素誘導因子 / 血管内皮増殖因子 / 血管内皮成長因子 / 解糖 / ミトコンドリア / HIF-1 / メトホルミン / Hypoxia / hypoxia / 動物モデル / mTOR / アロマターゼ / 疾患モデル / 腎被膜下移植法 / トランスレーショナルリサーチ / プロゲステロン / エストロゲン … More Except Principal Investigator 産婦人科学 / 体外受精胚移殖 / 産科学 / 難治性PCOS / 非主席卵胞 / 差婦人科学 / 難治性不妊症 / 体外受精・胚移植 / 小卵胞 / アロマターゼ / 生殖医学 / 動物実験モデル / NOGマウス / 腎被膜下移植 / エストロゲン / 子宮内膜癌 Less

FH gene mutation status and fumarate hydratase function in diffuse uterine leiomyomatosisPrincipal Investigator
- Principal Investigator
  
  石川博士
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Chiba University
Retrieval of mature oocytes from non-dominant follicles: a new therapy for PCOS
- Principal Investigator
  
  Shozu Makio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Chiba University
Role of angiogenesis and its inhibition in the surrounding myometrium for the development of uterine leiomyomaPrincipal Investigator
- Principal Investigator
  
  Ishikawa Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Chiba University
Morphology and functional analysis of mitochondria in uterine leiomyomaPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Chiba University
Aromatase induces ovulation via a reduction of follicular androgen and its application for infertility treatment
- Principal Investigator
  
  SHOZU Makio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Chiba University
Role of mTOR signaling pathway for the growth and proliferation of uterine leiomyomaPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Chiba University
Construction of xenograft models of human endometrial cancer in NOD/SCID IL-2R gamma null mice
- Principal Investigator
  
  KATO Kazuyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  公益財団法人がん研究会
   Chiba University
Establishment of a new xenograft model for uterine leiomyoma using sub-renal grafting technique in immunodeficient mice.Principal Investigator
- Principal Investigator
  
  ISHIKAWA Hiroshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Chiba University

All 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] Endometriosis Pathogenesis and Treatment (Harada Ed.)2014
- Author(s)
  Hiroshi Ishikawa and Makio Shozu
- Publisher
  Springer,
- Data Source
  KAKENHI-PROJECT-25253092
[Journal Article] Time-lapse monitoring of fertilized human oocytes focused on the incidence of 0PN embryos in conventional in vitro fertilization cycles. Kobayashi T, Ishikawa H, Ishii K, Sato A, Nakamura N, Saito Y, Hasegawa H, Fujita M, Mitsuhashi A, Shozu M.2021
- Author(s)
  Kobayashi T, Ishikawa H, Ishii K, Sato A, Nakamura N, Saito Y, Hasegawa H, Fujita M, Mitsuhashi A, Shozu M.
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1 Pages: 18862-18862
- DOI
  10.1038/s41598-021-98312-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09748, KAKENHI-PROJECT-19K09796, KAKENHI-PROJECT-19K18663
[Journal Article] Torsion of a Large Myomatous Uterus Associated with Progressive Renal Failure and Paralytic Ileus in an 86-Year-Old Woman.2019
- Author(s)
  Wang G, Ishikawa H, Sato A, Shozu M
- Journal Title
  
  Case Rep Obstet Gynecol
  
  Volume: - Pages: 1-5
- DOI
  10.1155/2019/1601368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09219, KAKENHI-PROJECT-19K18662
[Journal Article] High serum progesterone associated with infertility in a woman with nonclassic congenital adrenal hyperplasia.2017
- Author(s)
  Kawarai Y, Ishikawa H, Segawa T, Teramoto S, Tanaka T, Shozu M
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 印刷中 Issue: 5 Pages: 946-950
- DOI
  10.1111/jog.13288
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Journal Article] Local injection of diluted vasopressin followed by suction curettage for cervical ectopic pregnancy.2016
- Author(s)
  Ishikawa H, Unno Y, Omoto A, Shozu M.
- Journal Title
  
  Eur J Obstet Gynecol Reprod Biol
  
  Volume: 207 Pages: 173-177
- DOI
  10.1016/j.ejogrb.2016.11.004
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Journal Article] Elevated serum progesterone levels in postmenopausal women with mucinous ovarian tumors2016
- Author(s)
  Matsuoka A, Tate S, Nishikimi K, Ishikawa H, Shozu M
- Journal Title
  
  Menopause
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253092
[Journal Article] Spontaneous parasitic leiomyoma in a post-partum woman.2016
- Author(s)
  Iida M, Ishikawa H, Shozu M
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 42 Issue: 12 Pages: 1874-1877
- DOI
  10.1111/jog.13145
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Journal Article] Elevated serum progesterone levels in postmenopausal women with mucinous ovarian tumors2016
- Author(s)
  Matsuoka A, Tate S, Nishikimi K, Ishikawa H, Shozu M
- Journal Title
  
  Menopause
  
  Volume: 23 Issue: 5 Pages: 544-549
- DOI
  10.1097/gme.0000000000000587
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Journal Article] 子宮筋腫発育についての最新の理解2016
- Author(s)
  石川博士
- Journal Title
  
  産科と婦人科
  
  Volume: 83 Pages: 89-94
- Data Source
  KAKENHI-PROJECT-26462475
[Journal Article] Ovarian pregnancy associated with a fresh blastocyst transfer following in vitro fertilization2015
- Author(s)
  Ishikawa H, Sanada M, Shozu M
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 41 Issue: 11 Pages: 1823-1825
- DOI
  10.1111/jog.12790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462475, KAKENHI-PROJECT-15K15594
[Journal Article] Tubal pregnancy associated with additional conception in a contralateral tube2015
- Author(s)
  Ishikawa H, Kiyokawa T, Okayama J, Usui H, and Shozu M
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 41 Issue: 9 Pages: 1487-1490
- DOI
  10.1111/jog.12744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10703, KAKENHI-PROJECT-26462475, KAKENHI-PROJECT-15K15594
[Journal Article] Serous Tubal Intraepithelial Carcinoma in a Japanese Woman with a Deleterious BRCA1 Mutation2014
- Author(s)
  Ishikawa H, Kiyokawa T, Utsuno E, Matsushita K, Nomura F, Shozu M
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 44 Issue: 6 Pages: 597-601
- DOI
  10.1093/jjco/hyu035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592393
[Journal Article] Nonobese diabetic/severe combined immunodeficient murine xenograft model for human uterine leiomyoma.2014
- Author(s)
  Wang G, Ishikawa H, Sone K, Kobayashi T, Kim JJ, Kurita T, Shozu M.
- Journal Title
  
  Fertility and Sterility
  
  Volume: 印刷中 Issue: 5 Pages: 1485-1492.e3
- DOI
  10.1016/j.fertnstert.2014.01.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592393, KAKENHI-PROJECT-25253092, KAKENHI-PROJECT-25670694
[Journal Article] Giant multilocular sex cord tumor with annular tubules associated with precocious puberty2012
- Author(s)
  Ishikawa H, Kiyokawa T, Takatani T, Wang GW, Shozu M
- Journal Title
  
  Am J Obstet Gynecol
  
  Volume: 206(1) Issue: 1 Pages: e14-e16
- DOI
  10.1016/j.ajog.2011.09.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592393
[Journal Article] 婦人科内分泌療法腫瘍・類腫瘍 1 子宮筋腫2011
- Author(s)
  石川博士、生水真紀夫
- Journal Title
  
  臨床婦人科産科
  
  Volume: 65巻 Pages: 585-589
- Data Source
  KAKENHI-PROJECT-23592393
[Journal Article] 17beta-Hydroxysteroid Dehydrogenase-2 Deficiency and Progesterone Resistance in Endometriosis.2010
- Author(s)
  Bulun SE, Cheng YH, Pavone ME, Yin P, Imir G, Utsunomiya H, Thung S, Xue Q, Marsh EE, Tokunaga H, Ishikawa H, Kurita T, Su EJ.
- Journal Title
  
  Smin Reprod Med. 28(1)
  
  Pages: 44-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] LAT1 egulates Growth of Uterine Leiomyoma Smooth Muscle Cells.2010
- Author(s)
  Luo X, Coon JS 5th, Su E, Pearson EK, Yin P, Ishikawa H, Bulun SE.
- Journal Title
  
  Reprod Sci. 17(9)
  
  Pages: 791-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] Transcription Factor KLF11 Integrates Progesterone Receptor Signaling and Proliferation in Uterine Leiomyoma Cells.2010
- Author(s)
  Yin P, Lin Z, Reierstad S, Wu J, Ishikawa H, Marsh EE, Innes J, Cheng Y, Pearson K, Coon V JS, Kim JJ, Chakravarti D, Bulun SE.
- Journal Title
  
  Cancer Res. 70(4)
  
  Pages: 1722-1730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] Insulin-Like Growth Factor I Enhances the Expression of Aromatase P450 by Inhibiting Autophagy.2010
- Author(s)
  Zhang B, Shozu M, Okada M, Ishikawa H, Kasai T, Murakami K, Nomura K, Harada N, Inoue M.
- Journal Title
  
  Endocrinology. 151(10)
  
  Pages: 4949-4958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] Progesterone is essential for maintenance and growth of uterine leiomyoma.2010
- Author(s)
  Ishikawa H, Ishi K, Serna VA, Kakazu R, Bulun SE, Kurita T
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 2433-2442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] Progesterone is essential for maintenance and growth of uterine leiomyoma.2010
- Author(s)
  Ishikawa H, Ishi K, Serna VA, Kakazu T, Bulun SE, Kurita T.
- Journal Title
  
  Endocrinology. 151(6)
  
  Pages: 2433-2442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] LAT1 regulates growth of uterine leiomyoma smooth muscle cells.2010
- Author(s)
  Luo X, Coon JS 5^<th>, Su E, Peason EK, Yin P, Ishikawa H, Bulun SE.
- Journal Title
  
  Reproductive Science
  
  Volume: 17 Pages: 791-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] High Aromatase Expression in Uterine Leiomyoma Tissues of African-American Women.2009
- Author(s)
  Ishikawa H, Reierstad S, Demura M, Rademaker AW, Kasai T, Inoue M, Usui H, Shozu M, Bulun SE.
- Journal Title
  
  J Clin Endocrinol Metab. 94(5)
  
  Pages: 1752-1756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Journal Article] Progesterone and Mifepristone Regulate L-Type Amino Acid Transporter 2 and 4F2 Heavy Chain Expression in Uterine Leiomyoma Cells.2009
- Author(s)
  Luo X, Yin P, Reierstad S, Ishikawa H, Lin Z, Pavone ME, Zhao H, Marsh EE, Bulun SE.
- Journal Title
  
  J Clin Endocrinol Metab. 94(11)
  
  Pages: 4533-4539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] VEGF and VEGF receptor expression in pseudocapsule of uterine leiomyoma2021
- Author(s)
  Yanruo Zhou, Hiroshi Ishikawa, Taichi Wake, Tetsuji Nishiwaki, Makio Shozu
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09219
[Presentation] 胚培養液中Cell Free DNAを用いたPGT-Aの可能性2020
- Author(s)
  曽根原弘樹、小林達也、中山順樹、石川聖華、石川博士、碓井宏和、生水真紀夫
- Organizer
  第65回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-19K09748
[Presentation] タイムラプスモニタリングによる前核確認では0PN由来胚の発生頻度が減少する2020
- Author(s)
  小林達也、石川博士、石井久美子、佐藤明日香、中村名律子、齊藤佳子、藤田真紀、生水真紀夫
- Organizer
  第65回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-19K09748
[Presentation] 子宮筋腫の薬物療法-GnRHアンタゴニストの使用経験を含めて-2019
- Author(s)
  石川博士
- Organizer
  水戸臨床婦人科懇話会
- Data Source
  KAKENHI-PROJECT-18K09219
[Presentation] 産婦人科における黄体ホルモン療法　-妊娠合併症から子宮がんまで-2019
- Author(s)
  石川博士
- Organizer
  第92回日本内分泌学会
- Data Source
  KAKENHI-PROJECT-18K09219
[Presentation] Inhibition of HIF-1 blocks uterine leiomyoma growth both in vitro and in vivo.2019
- Author(s)
  Ishikawa H, Xu L, Kobayashi T, Shozu M
- Organizer
  5th ,Congress of SEUD, Society of endometriosis and uterine disorders
- Data Source
  KAKENHI-PROJECT-18K09219
[Presentation] 子宮筋腫の薬物療法　-働く女性のQOL向上をめざして-2019
- Author(s)
  石川博士
- Organizer
  第24回日本女性医学会ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-18K09219
[Presentation] Inhibition of HIF-1 using echinomycin inhibits cell proliferation and induces apoptosis in uterine leiomyoma.2019
- Author(s)
  Ishikawa H, Nishiwaki T, Shozu M
- Organizer
  第71回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18K09219
[Presentation] Hypoxia induced cell proliferation and apoptosis in uterine leiomyoma and myometrial cells2017
- Author(s)
  Ishikawa H, Nishiwaki T, Shozu M
- Organizer
  第69回日本産科婦人科学会学術講演会
- Place of Presentation
  リーガロイヤルホテル広島（広島県　広島市）
- Year and Date
  2017-04-13
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Local injection of diluent vasopressin followed by suction curettage as initial treatment of cervical ectopic pregnancy.2016
- Author(s)
  Ishikawa H,Shinno R, Omoto A, Unno Y, Usui H, Shozu M
- Organizer
  European society of Human Reproduction and Embryology 32nd annual meeting
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2016-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Hypoxic response mediated by hypoxia inducible factor-1α in uterine leiomyoma and myometrium2016
- Author(s)
  Hiroshi Ishikawa, LinLin Xu, Tatsuya Kobayashi, Guiwen Wang, Makio Shozu
- Organizer
  Society for Reproductive Investigation 6３ｒｄ annual meeting
- Place of Presentation
  モントリオール、カナダ
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Giant ovarian endometriotic cyst associated with non-communicating rudimentary uterine horn in the absence of dysmenorrhea in an adolescent girl.2016
- Author(s)
  Ishikawa H, Kawarai Y, Hayashida H, Kawano M, Shozu M
- Organizer
  5th Asian Conference on Endometriosis
- Place of Presentation
  大阪国際会議場（大阪府　大阪市）
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Hypoxic response mediated by hypoxia inducible factor-1α in uterine leiomyoma and myometrium2016
- Author(s)
  Ishikawa H, Sone K, Wang G, Nishiwaki T, Shozu M
- Organizer
  第68回日本産婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都　千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Hypoxia induces hypoxia inducible factor-1α (HIF-1α) and its related gene expression in uterine leiomyoma2016
- Author(s)
  Ishikawa H
- Organizer
  3rd Congress of the Society of Endometriosis and Uterine disorders
- Place of Presentation
  Singapore, Singapore
- Year and Date
  2016-04-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Hypoxic response mediated by hypoxia inducible factor-1α in uterine leiomyoma and myometrium2016
- Author(s)
  ISHIKAWA Hiroshi, SONE Kunizui, WANG Gui Wen, NISHIWAKI Tetsuji, SHOZU Makio
- Organizer
  第68回日本産科婦人科学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] 子宮筋腫では低酸素により低酸素誘導因子HIF1の発現が誘導される2015
- Author(s)
  石川博士、徐　琳琳、曽根国瑞、西脇哲二、生水真紀夫
- Organizer
  第67回日本産科婦人科学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] アロマターゼ阻害剤はマウス体外培養卵法のFshrを増加させる2015
- Author(s)
  小林達也、石川博士、石井久美子、生水真紀夫
- Organizer
  第33回日本受精着床学会総会学術講演会
- Place of Presentation
  TFTホール西館（東京都江東区）
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 重症免疫不全マウスの腎被膜下移植子宮筋腫xenograftモデル2015
- Author(s)
  石川　博士、王　桂文、小林　達也、生水　真紀夫
- Organizer
  第19回　日本生殖内分泌学会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府大阪市）
- Year and Date
  2015-01-10
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] 子宮筋腫・子宮筋におけるHIF-1αの発現とHIFを介した低酸素反応の検討2015
- Author(s)
  石川　博士、曽根　国瑞、徐　琳琳、小林　達也、生水　真紀夫
- Organizer
  第33回内分泌代謝サマーセミナー
- Place of Presentation
  柳川藩主立花亭御花（福岡県柳川市）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Expression of luteinizing hormone receptor and concentrations of gonadotropin and sex steroids in non-growing small follicles at oocyte retrieval for in vitro fertilization2015
- Author(s)
  Ishikawa H, Okubo T, Kobayashi T, Kanetani H, Segawa T, Teramoto S, Shozu M
- Organizer
  IFFS/JSRM International Meeting 2015 in Yokohama
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-26
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 重症免疫不全マウス子宮筋腫xenograftモデルの遺伝子発現解析2014
- Author(s)
  石川博士、王　桂文、河原井麗正、大見健二、生水真紀夫
- Organizer
  第66回日本産科婦人科学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 当科における自然周期、卵巣低刺激周期採卵の検討2014
- Author(s)
  石川博士、小林達也、石井久美子、河原井麗正、金谷裕美、藤田真紀、柿沼敏行、生水真紀夫
- Organizer
  第15回千葉リプロダクション研究会学術講演会
- Place of Presentation
  三井ガーデンホテル千葉（千葉県千葉市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 不妊診療における新試薬「iE2」の評価に関する検討2013
- Author(s)
  瀬川智也、寺元章吉、宮内修、渡邉芳明、篠原一朝、土山哲史、石川博士、柿沼敏行、生水真紀夫
- Organizer
  第147回関東生殖医学会
- Place of Presentation
  持田製薬ルークホール（東京都新宿区）
- Year and Date
  2013-04-20
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 子宮筋腫低酸素培養下におけるHypoxia inducible factor-1αの発現低下2013
- Author(s)
  石川博士、川野みどり、王桂文、河原井麗正、大見健二、生水真紀夫
- Organizer
  第65回日本産科婦人科学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 不妊を契機に発見された21水酸化酵素欠損症の1例2013
- Author(s)
  河原井麗正、石川博士、小林達也、金谷裕美、藤田真紀、川野みどり、柿沼敏行、永野秀和、田中知明、瀬川智也、寺元章吉、生水真紀夫
- Organizer
  第147回関東生殖医学会
- Place of Presentation
  持田製薬ルークホール（東京都新宿区）
- Year and Date
  2013-04-20
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 不妊を契機に診断された21水酸化酵素欠損症の1例2013
- Author(s)
  河原井麗正、石川博士、小林達也、金谷裕美、藤田真紀、川野みどり、柿沼敏行、永野秀和、田中知明、瀬川智也、寺元章吉、生水真紀夫
- Organizer
  第13回千葉内分泌･代謝談話会
- Place of Presentation
  千葉大学医学部附属病院（千葉県千葉市）
- Year and Date
  2013-08-29
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 子宮筋腫の免疫不全マウス移植モデルにおける、宿主と移植方法の検討2013
- Author(s)
  石川博士、王　桂文、曽根国瑞、大見健二、川野みどり、木原真紀、生水真紀夫
- Organizer
  第65回日本産科婦人科学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] Optimization of a uterine leiomyoma xenograft model using different immunodeficient mice and grafting procedures.2012
- Author(s)
  Ishikawa H, Wang GW, Ohmi K, Sone K, Kawano M, Kihara M, Shozu M
- Organizer
  15th　International Congress of Endocrinology
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] Altered expression of hypoxia inducible factor-1 in uterine leiomyoma under hypoxic and normoxic condition2012
- Author(s)
  Ishikawa H, Kawarai Y, Takizawa S, Wang GW, Shozu M
- Organizer
  15th International Congress of Hormonal Steroids and Hormones & Cancer
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 子宮筋腫のXenograft model2012
- Author(s)
  石川博士
- Organizer
  第3回婦人科ホルモン依存性疾患研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 子宮筋腫の免疫不全マウス移植モデルにおける、宿主と移植方法の検討2012
- Author(s)
  石川博士、王桂文、曽根国瑞、大見健二、川野みどり、木原真紀、生水真紀夫
- Organizer
  第64回日本産科婦人科学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] Altered expression of hypoxia inducible factor-1 in uterine leiomyoma under hypoxic and normoxic condition.2012
- Author(s)
  Ishikawa H, Kawarai Y, Takizawa S, Wang GW, Shozu M
- Organizer
  15th　International Congress of Hormonal Steroids and Hormones & Cancer
- Place of Presentation
  Kanazawa, Japan
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 子宮筋腫のマウス腎被膜下移植モデルへの遺伝子導入実験-子宮筋腫の分子標的治療を目指して-2011
- Author(s)
  石川博士、王桂文、曽根国瑞、藤田真紀、大見健二、生水真紀夫
- Organizer
  第63回日本産科婦人科学会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 子宮筋腫増殖の鍵はエストロゲンではなく、プロゲステロンである:マウス腎被膜下移植法を用いた新しい動物実験モデルによる検討から2010
- Author(s)
  石川博士、碓井宏和、木原真紀、川野みどり、生水真紀夫
- Organizer
  第62回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2010-04-03
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] マウス腎被膜下移植法を用いた、ヒト子宮筋腫動物実験モデルの作製2010
- Author(s)
  王桂文、石川博士、大見健二、生水真紀夫
- Organizer
  平成22年度千葉医学会例会産婦人科部会
- Place of Presentation
  千葉
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Evaluation of NOD/SCID and nude mice as the host for human uterine leiomyoma xenografts.2010
- Author(s)
  Ishikawa H, Wang GW, Sone K, Kurita T, Shozu M
- Organizer
  Advances in Uterine Leiomyoma Research : 3rd NIH International Congress.
- Place of Presentation
  Bethesda, MD, USA.
- Year and Date
  2010-11-23
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Optimization of a uterine leiomyoma xenograft model using different immunodeficient mice and grafting procedures2010
- Author(s)
  Ishikawa H, Wang GW, Ohmi K, Sone K, Kawano M, Kihara M, Shozu M
- Organizer
  15th International Congress of Endocrinology
- Place of Presentation
  Florence, Italy
- Year and Date
  2010-05-09
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] Novel in vivo disease model for human uterine leiomyoma : a powerful tool for discovering new therapies.2010
- Author(s)
  Ishikawa H, Ishi K, Shozu M, Bulun SE, Kurita T
- Organizer
  20th World Congress on Fertility and Sterility.
- Place of Presentation
  Munich, Germany.
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] 子宮筋腫増殖の鍵はエストロゲンではなくプロゲステロンである:マウス腎被膜下移植法を用いた、新しい動物実験モデルによる検討から2010
- Author(s)
  石川博士、碓井宏和、川野みどり、木原真紀、生水真紀夫
- Organizer
  第62回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Evaluation of NOD/SCID and nude mice as the host for human uterine leiomyoma xenograft.2010
- Author(s)
  Ishikawa H, Wang GW, Sone K, Kurita T, Shozu M
- Organizer
  Advances in Uterine Leiomyoma Research : 3^<rd> NIH International Congress
- Place of Presentation
  Bethesda, MD, United States
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Progesterone is a key player for the growth maintenance of uterine leiomyoma.2010
- Author(s)
  Ishikawa H, Ishi K, Shozu M, Bulun SE, Kurita T
- Organizer
  14th International Congress of Endocrinology.
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Novel in vivo disease model for human uterine leiomyoma : a powerful tool for discovering new therapies2010
- Author(s)
  Ishikawa H, Ishi K, Shozu M, Bulun SE, Kurita T
- Organizer
  20^<th> World Congress on Fertility and Sterility
- Place of Presentation
  Munich, Germany
- Year and Date
  2010-09-12
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Estrogen and progesterone are concurrently required for uterine leiomyoma enlargement in a novel in vivo model.2009
- Author(s)
  Ishikawa H, Ishi K, Kakazu R, Bulun SE, Kurita T
- Organizer
  American Society for Reproductive Medicine, 65th Annual Meeting.
- Place of Presentation
  Atlanta, USA
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] 重症免疫不全マウス腎被膜下移植法を用いた新しい子宮筋腫in vivo実験モデル2009
- Author(s)
  石川博士、碓井宏和、木原真紀、川野みどり、金谷裕美、生水真紀夫
- Organizer
  第140回日本生殖医学会関東地方部会
- Place of Presentation
  千葉
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Estrogen and progesterone are concurrently required for uterine leiomyoma enlargement in a novel in vivo model.2009
- Author(s)
  石川博士
- Organizer
  American Society for Reproductive Medicine, 65th Annual Meeting
- Place of Presentation
  米国アトランタ
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] 子宮筋腫はプロゲステロン依存性腫瘍である-新しい動物実験モデルを使った検証から-2009
- Author(s)
  石川博士、金谷裕美、川野みどり、木原真紀、生水真紀夫
- Organizer
  第14回日本生殖内分泌学会
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21890038
[Presentation] Hypoxia induces hypoxia- inducible factor-1 alpha in uterine leiomyoma cells
- Author(s)
  Ishikawa H, Sone K, Xu L, Kobayashi T, Shozu M
- Organizer
  Society for Reproductive Investigation 62nd annual meeting
- Place of Presentation
  San Francisco, CA, United States
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] Oocyte retrival from collateral follicles improves outcomes of natural or low ovarian stimulus cycle IVF
- Author(s)
  Segawa T, Teramoto S, Miyauchi O, Watanabe Y, Hayashi T, Ohkubo T, Onda N, Ueno T, Tsuchiyama S, Shinohara K, Yelian F, Ishikawa H, Shozu M
- Organizer
  European Society of Human Reproduction and Embryology Annual Meeting
- Place of Presentation
  London, U.K
- Year and Date
  2013-07-07 – 2013-07-10
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 子宮筋腫のXenograft model
- Author(s)
  石川博士
- Organizer
  第3回婦人科ホルモン依存性疾患研究会
- Place of Presentation
  東京都
- Invited
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] 小卵胞由来MⅡ卵子を採卵する意義に関する検討
- Author(s)
  瀬川智也、寺元章吉、宮内修、渡邉芳明、林輝明、大久保毅、恩田智幸、松尾涼子、上野剛、田口智美、水口麻侑子、久手堅舞、篠原一朝、土山哲史、石川博士、柿沼敏行、生水真紀夫
- Organizer
  第31回日本受精着床学会総会・学術講演会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2013-08-08 – 2013-08-09
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 高アンドロゲン血症をきたした内分泌腫瘍の3例
- Author(s)
  河原井麗正、石川博士、柿沼敏行、藤田真紀、金谷裕美、川野みどり、清川貴子、生水真紀夫
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 自然周期における主席卵胞および小卵胞由来の顆粒膜細胞内LH受容体発現量が卵子成熟度に与える影響
- Author(s)
  大久保毅、生水真紀夫、石川博士、瀬川智也、宮内修、林輝明、恩田知幸、松尾涼子、上野剛、寺元章吉
- Organizer
  第32回日本受精着床学会総会・学術講演会
- Place of Presentation
  ハイアットリージェンシー東京（東京都新宿区）
- Year and Date
  2014-07-31 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 子宮筋腫では低酸素により低酸素誘導因子HIF1の発現が誘導される
- Author(s)
  石川　博士、徐　琳琳、曽根　国瑞、西脇　哲二、生水　真紀夫
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-26462475
[Presentation] 自然排卵周期における新試薬「iE2」の評価に関する検討
- Author(s)
  瀬川智也、寺元章吉、宮内修、渡邉芳明、黒田雅子、篠原一朝、土山哲史、石川博士、柿沼敏行、生水真紀夫
- Organizer
  第58回日本生殖医学会学術講演会･総会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2013-11-15 – 2013-11-16
- Data Source
  KAKENHI-PROJECT-25253092
[Presentation] 子宮筋腫のマウス腎被膜下移植モデルへの遺伝子導入実験　-子宮筋腫の分子標的治療を目指して-
- Author(s)
  石川博士、王桂文、曽根国瑞、藤田真紀、大見健二、生水真紀夫
- Organizer
  第63回日本産科婦人科学会学術講演会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23592393
[Presentation] A Case of Nonclassic Congenital Adrenal Hyperplasia in Which Aberrant Serum Progesterone Provides a Diagnostic Clue
- Author(s)
  Kawarai Y, Ishikawa H, Segawa T, Nagano H, Tanaka T, and Shozu M.
- Organizer
  The Endocrine Society's 96th Annual Meeting & EXPO (ENDO 2014）
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-06-21 – 2014-06-24
- Data Source
  KAKENHI-PROJECT-25253092

1. SHOZU Makio (30226302)

# of Collaborated Projects: 6 results

# of Collaborated Products: 51 results
2. 小林達也 (00645640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. KATO Kazuyoshi (80399451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MITSUHASHI Akira (40302541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 幡野雅彦 (20208523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 花岡英紀 (80361426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 碓井宏和 (90375634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 甲賀かをり (10396723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 後藤優希 (80984476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. XU Linlin

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Ishikawa Hiroshi 石川 博士

ISHIKAWA Hiroshi 石川 博士

Research Projects

Research Products

Co-Researchers

FH gene mutation status and fumarate hydratase function in diffuse uterine leiomyomatosisPrincipal Investigator

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Retrieval of mature oocytes from non-dominant follicles: a new therapy for PCOS

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Role of angiogenesis and its inhibition in the surrounding myometrium for the development of uterine leiomyomaPrincipal Investigator

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Review Section

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Morphology and functional analysis of mitochondria in uterine leiomyomaPrincipal Investigator

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Aromatase induces ovulation via a reduction of follicular androgen and its application for infertility treatment

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Role of mTOR signaling pathway for the growth and proliferation of uterine leiomyomaPrincipal Investigator

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Construction of xenograft models of human endometrial cancer in NOD/SCID IL-2R gamma null mice

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Research Institution

Establishment of a new xenograft model for uterine leiomyoma using sub-renal grafting technique in immunodeficient mice.Principal Investigator

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Research Institution

[Book] Endometriosis Pathogenesis and Treatment (Harada Ed.)2014

Author(s)

Publisher

Data Source

[Journal Article] Time-lapse monitoring of fertilized human oocytes focused on the incidence of 0PN embryos in conventional in vitro fertilization cycles. Kobayashi T, Ishikawa H, Ishii K, Sato A, Nakamura N, Saito Y, Hasegawa H, Fujita M, Mitsuhashi A, Shozu M.2021

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[Journal Article] Torsion of a Large Myomatous Uterus Associated with Progressive Renal Failure and Paralytic Ileus in an 86-Year-Old Woman.2019

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[Journal Article] High serum progesterone associated with infertility in a woman with nonclassic congenital adrenal hyperplasia.2017

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[Journal Article] Local injection of diluted vasopressin followed by suction curettage for cervical ectopic pregnancy.2016

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[Journal Article] Elevated serum progesterone levels in postmenopausal women with mucinous ovarian tumors2016

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Ishikawa Hiroshi 石川博士

ISHIKAWA Hiroshi 石川博士

[Journal Article] 婦人科内分泌療法腫瘍・類腫瘍 1 子宮筋腫2011