Yamasaki Norimasa 山崎憲政

… Alternative Names

山崎憲政ヤマサキノリマサ

YAMASAKI Norimasa 山崎憲政

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Researcher Number	70564136
Other IDs
Affiliation (Current)	2025: 広島大学, 技術センター, 技術主任
Affiliation (based on the past Project Information) *help	2023: 広島大学, 技術センター, 技術主任 2016 – 2017: 広島大学, 技術センター, 技術主任 2014: 広島大学, 技術センター, 技術主任 2013: 広島大学, 技術センター, 技術員
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 造血幹細胞 / ヒストン脱メチル化酵素 / 枯草菌ベクター / T細胞受容体 / 免疫系ヒト化マウス / ノックインマウス / ゲノム編集 / T 細胞受容体 / ゲノム再構築 / 枯草菌ゲノムベクター … More / Jmjd3 / コンディショナルノックアウトマウス / Jmjd3(Kdm6b) / ノックアウトマウス / エピジェネティクス / 白血病 / JMJD3 / トランスジェニックマウス / Fbxl10 Less

ヒトT細胞受容体ゲノムをノックインした新しい免疫系ヒト化マウスの樹立Principal Investigator
- Principal Investigator
  
  山崎憲政
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hiroshima University
JMJD3 plays essential roles in the maintenance of hematopoietic stem cells and leukemic stem cells.Principal Investigator
- Principal Investigator
  
  Yamasaki Norimasa
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Hiroshima University
Analysis of leukemogenic mechanisms by deregulated histone methylationPrincipal Investigator
- Principal Investigator
  
  YAMASAKI Norimasa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Hiroshima University

All 2024 2023 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] JPH203, a LAT1 inhibitor, alleviates steroid‐resistant murine airway inflammation mediated by Th17 cells2023
- Author(s)
  Hayashi Keitaro、Saeki Mayumi、Miura Kento、Yamasaki Norimasa、Matsuda Masaya、Shimora Hayato、Nabe Takeshi、Shimizu Yasuo、Fujita Tomoe、Endou Hitoshi、Kaminuma Osamu
- Journal Title
  
  Allergy
  
  Volume: 78 Issue: 10 Pages: 2780-2783
- DOI
  10.1111/all.15798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-22H00398
[Journal Article] MBTD1 preserves adult hematopoietic stem cell pool size and function2023
- Author(s)
  Takubo Keiyo、Htun Phyo Wai、Ueda Takeshi、Sera Yasuyuki、Iwasaki Masayuki、Koizumi Miho、Shiroshita Kohei、Kobayashi Hiroshi、Haraguchi Miho、Watanuki Shintaro、Honda Zen-ichiro、Yamasaki Norimasa、Nakamura-Ishizu Ayako、Arai Fumio、Motoyama Noboru、Hatta Tomohisa、Natsume Tohru、Suda Toshio、Honda Hiroaki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 32
- DOI
  10.1073/pnas.2206860120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16333, KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-23K27442
[Journal Article] Generation of reporter mice for detecting the transcriptional activity of nuclear factor of activated T cells2023
- Author(s)
  Yamasaki Norimasa、Miura Kento、Ogata Sawako、Miura Shuka、Uchimura Arikuni、Satoh Yasunari、Toshishige Masaaki、Hosomi Naohisa、Gamboa Maribet、Kitamura Noriko、Kaminuma Osamu
- Journal Title
  
  Exp. Anim.
  
  Volume: 72 Issue: 4 Pages: 454-459
- DOI
  10.1538/expanim.23-0043
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-22H00398
[Journal Article] Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.2017
- Author(s)
  Nakata Y, Ueda T, Nagamchi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood
  
  Volume: 129(15) Pages: 2148-2160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18418
[Journal Article] ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.2016
- Author(s)
  Ueda T, Nakata Y, Yamasaki N, Oda H, Sentani K, Kanai A, Onishi N, Ikeda K, Sera Y, Honda Zi, Tanaka K, Sata M, Ogawa S, Yasui W, Saya H, Takita J, Honda H.
- Journal Title
  
  Oncogene.
  
  Volume: 35(34) Pages: 4447-4458
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K18418
[Journal Article] Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency.2016
- Author(s)
  Ikeda K, Ueda T, Yamasaki N, Nakata Y, Sera Y, Nagamachi A, Miyama T, Kobayashi H, Takubo K, Kanai A, Oda H, Wolff L, Honda Z, Ichinohe T, Matsubara A, Suda T, Inaba T, Honda H.
- Journal Title
  
  Scientific Reports.
  
  Volume: 6 Pages: 29454-29454
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18418
[Journal Article] Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.2016
- Author(s)
  Sera Y, Yamasaki N, Oda H, Nagamachi A, Wolff L, Inukai T, Inaba T, Honda H.
- Journal Title
  
  Cancer Science.
  
  Volume: 107(7) Pages: 890-898
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18418
[Journal Article] Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.2016
- Author(s)
  Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Sera Y, Sasaki M, Matsui M, Honda Z, Oda H, Wolff L, Inaba T, Honda H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 113(37) Pages: 10370-10375
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K18418
[Journal Article] Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and up regulation of Nsg2.2015
- Author(s)
  Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K, Konuma T, Oda H, Wolff L, Honda ZI, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood
  
  Volume: 125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830081
[Journal Article] Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function.2014
- Author(s)
  Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, Honda Zi, Takubo K, Suda T, Oda H, Inaba T, Honda H.
- Journal Title
  
  PLOS ONE.
  
  Volume: 9(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830081
[Journal Article] CIZ1, a p21Cip/Waf1-interacting protein, function as a tumor suppressor in vivo.2013
- Author(s)
  Nishibe R, Watanabe W, Ueda T, Yamasaki N, Koller R, Wolff L, Honda Zi, Ohtsubo M, Honda H.
- Journal Title
  
  FEBS Letters.
  
  Volume: 587(10) Pages: 1529-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830081
[Presentation] 枯草菌ゲノムベクターを用いたヒト TCR 遺伝子座の再構築2024
- Author(s)
  諸角光祐、岩田哲郎、山崎憲政、神沼修、廣田順二、
- Organizer
  日本農芸化学会 2024 年度大会
- Data Source
  KAKENHI-PROJECT-23K07134
[Presentation] Roles of UTX, a histone H3K27 demethylase, in normal hematopoiesis and hematologic malignancies.2017
- Author(s)
  Yasuyuki Sera, Takeshi Ueda, YuIchiro Nakata, Ken-Ichiro Ikeda, Norimasa Yamasaki, Hideaki Oda, Akiko Nagamachi, Akinori Kanai, Toshio Suda, Keiyo Takubo, Hiroaki Honda.
- Organizer
  第78回日本血液学会
- Data Source
  KAKENHI-PROJECT-16K18418
[Presentation] JMJD3 plays essential roles in the maintenance of hematopoietic stem cells and leukemic stem cells through the regulation of p16INK4a.2017
- Author(s)
  Yuichiro Nakata, Norimasa Yamasaki, Takeshi Ueda, Kenichiro Ikeda, Akiko Nagamachi, Toshiya Inaba and Hiroaki Honda.
- Organizer
  第55回アメリカ血液学会
- Data Source
  KAKENHI-PROJECT-16K18418

1. 岩田哲郎 (30771563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 三浦健人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 世良康如

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamasaki Norimasa 山崎 憲政

山崎 憲政 ヤマサキ ノリマサ

YAMASAKI Norimasa 山崎 憲政

Research Projects

Research Products

Co-Researchers

ヒトT細胞受容体ゲノムをノックインした新しい免疫系ヒト化マウスの樹立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

JMJD3 plays essential roles in the maintenance of hematopoietic stem cells and leukemic stem cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of leukemogenic mechanisms by deregulated histone methylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] JPH203, a LAT1 inhibitor, alleviates steroid‐resistant murine airway inflammation mediated by Th17 cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MBTD1 preserves adult hematopoietic stem cell pool size and function2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of reporter mice for detecting the transcriptional activity of nuclear factor of activated T cells2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.2017

Author(s)

Journal Title

Data Source

[Journal Article] ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.2016

Author(s)

Journal Title

Data Source

[Journal Article] Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency.2016

Author(s)

Journal Title

Data Source

[Journal Article] Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.2016

Author(s)

Journal Title

Data Source

[Journal Article] Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.2016

Author(s)

Journal Title

Data Source

[Journal Article] Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and up regulation of Nsg2.2015

Author(s)

Journal Title

Data Source

[Journal Article] Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function.2014

Author(s)

Journal Title

Data Source

[Journal Article] CIZ1, a p21Cip/Waf1-interacting protein, function as a tumor suppressor in vivo.2013

Author(s)

Journal Title

Data Source

[Presentation] 枯草菌ゲノムベクターを用いたヒト TCR 遺伝子座の再構築2024

Author(s)

Organizer

Data Source

[Presentation] Roles of UTX, a histone H3K27 demethylase, in normal hematopoiesis and hematologic malignancies.2017

Author(s)

Organizer

Yamasaki Norimasa 山崎憲政

山崎憲政ヤマサキノリマサ

YAMASAKI Norimasa 山崎憲政