Hori Kei 堀啓

… Alternative Names

HORI Kei 堀啓

Less

Researcher Number	70568790
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所代謝研究部, 室長 2016 – 2018: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所代謝研究部, 室長 2013 – 2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所代謝研究部, 室長 2012: 独立行政法人国立精神・神経医療研究センター, 神経研究所病態生化学研究部, 科研費研究員 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所病態生化学研究部, 流動研究員
Review Section/Research Field	Principal Investigator Neurophysiology / General neuroscience / Basic Section 51030:Pathophysiologic neuroscience-related / Neuroscience in general
Keywords	Principal Investigator AUTS2 / 自閉症 / 精神疾患 / シナプス / 自閉症感受性遺伝子 / 大脳皮質 / アクチン細胞骨格 / 細胞骨格 / 神経突起伸長 / 神経細胞移動 … More / エピジェネティクス / 遺伝子発現制御 / 遺伝子発現 / 海馬 / 大脳 / 記憶学習 / 音声コミュニケーション / スパイン / 神経回路 / Rac1 / Racシグナリング / プロテオミクス / 行動解析 / 再生神経科学 / 発達 / 発生 Less

シナプス発達に関わる自閉症関連遺伝子AUTS2の新規転写制御機構の解明Principal Investigator
- Principal Investigator
  
  堀啓
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  National Center of Neurology and Psychiatry
The role of AUTS2 in synaptic formation and the cognitive brain functionsPrincipal Investigator
- Principal Investigator
  
  Hori Kei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Center of Neurology and Psychiatry
Analysis of the role of autism susceptibility candidate gene Auts2 in brain development.Principal Investigator
- Principal Investigator
  
  HORI Kei
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Center of Neurology and Psychiatry
Analysis of the molecular function of a novel autism susceptibility gene AUTS2 in cerebellar developmentPrincipal Investigator
- Principal Investigator
  
  HORI Kei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  National Center of Neurology and Psychiatry

All 2022 2018 2017 2016 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3?Ubiquitin Ligases and Intronic miR-1402018
- Author(s)
  Ambrozkiewicz MC、Schwark M、Kishimoto-Suga M、Borisova E、Hori K、Salazar-L?zaro A、Rusanova A、Altas B、Piepkorn L、Bessa P、Schaub T、Zhang X、Rabe T、Ripamonti S、Ros?rio M、Akiyama H、Jahn O、Kobayashi T、Hoshino M、Tarabykin V、Kawabe H
- Journal Title
  
  Neuron
  
  Volume: 100 Issue: 5 Pages: 1097-1115
- DOI
  10.1016/j.neuron.2018.10.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06528, KAKENHI-PROJECT-18H02538, KAKENHI-PROJECT-16K07021, KAKENHI-PROJECT-15H04268, KAKENHI-PROJECT-15K21769
[Journal Article] Neuronal Migration and AUTS2 Syndrome2017
- Author(s)
  Kei Hori、Mikio Hoshino
- Journal Title
  
  Brain Sciences
  
  Volume: 7 Issue: 5 Pages: 54-54
- DOI
  10.3390/brainsci7050054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07021, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06528
[Journal Article] Glycosphingolipid metabolic reprogramming drives neural differentiation2017
- Author(s)
  Russo D, Della Ragione F, Rizzo R, Sugiyama E, Scalabri F, Hori K, Capasso S, Sticco L, Fioriniello S, De Gregorio R, Granata I, Guarracino MR, Maglione V, Johannes L, Bellenchi GC, Hoshino M, Setou M, D'Esposito M, Luini A, D'Angelo G.
- Journal Title
  
  The EMBO Journal
  
  Volume: 37 Issue: 7
- DOI
  10.15252/embj.201797674
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07021, KAKENHI-PLANNED-16H06528
[Journal Article] Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox92016
- Author(s)
  Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M
- Journal Title
  
  Mech Dev
  
  Volume: 140 Pages: 25-40
- DOI
  10.1016/j.mod.2016.02.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01304, KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-15H04268, KAKENHI-PROJECT-15K14337, KAKENHI-PROJECT-24300138, KAKENHI-PROJECT-16K07021, KAKENHI-PROJECT-16K10004, KAKENHI-PLANNED-16H06528
[Journal Article] Cytoskeletal regulation of AUTS2 in neuronal migration and neuritogenesis.2014
- Author(s)
  Hori K., Nagai T., Shan W., Sakamoto A., Taya S., Hashimoto R., Hayashi T., Abe M., Yamazaki M., Nakao K., Nishioka T., Sakimura K., Yamada K., Kaibuchi K., Hoshino M.
- Journal Title
  
  Cell Reports
  
  Volume: 9 Issue: 6 Pages: 2166-2179
- DOI
  10.1016/j.celrep.2014.11.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J08610, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24300138, KAKENHI-PROJECT-24500387, KAKENHI-PROJECT-24500399, KAKENHI-PUBLICLY-25110742, KAKENHI-PUBLICLY-25115733, KAKENHI-PROJECT-25830030
[Journal Article] GABAergic neuron specification in the spinal cord, the cerebellum and the cochlear nucleus2012
- Author(s)
  Hori K and Hoshino M
- Journal Title
  
  Neural Plast
  
  Pages: 11-11
- Data Source
  KAKENHI-PROJECT-23700406
[Journal Article] GABAergic neuron specification in the spinal cord, the cerebellum, and the cochlear nucleus.2012
- Author(s)
  Kei Hori
- Journal Title
  
  Neural Plast.
  
  Volume: 2012 (2012) Pages: 921732-921732
- DOI
  10.1155/2012/921732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700406, KAKENHI-PROJECT-24300138, KAKENHI-PROJECT-24650184, KAKENHI-PUBLICLY-23110529
[Journal Article] Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system.2011
- Author(s)
  Kim EJ, Hori K, Wyckoff A, Dickel LK, Koundakjian EJ, Goodrich LV, Johnson JE.
- Journal Title
  
  J Comp Neurol
  
  Volume: 519 Issue: 7 Pages: 1355-1370
- DOI
  10.1002/cne.22574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] 神経発達に関わる自閉症感受性遺伝子AUTS2の機能とその破綻メカニズムに関する研究2022
- Author(s)
  堀啓
- Organizer
  第49回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07385
[Presentation] The role of AUTS2 in synaptic organization and the cognitive functions during postnatal brain development2018
- Author(s)
  堀　啓
- Organizer
  第61回日本神経化学会大会（神戸国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] Loss of Auts2 induces the defects of synaptic function and cognitive brain functions2018
- Author(s)
  Hori K, Nagai T, Shan W, Yamada M, Shiraishi R, Sakamoto A, Kanno K, Abe M, Yamada K, Sakimura K and Hoshino M.
- Organizer
  新学術領域個性創発脳第1回国際シンポジウム「Toward Understanding “INDIVISUALITY”」（京都大学芝蘭会館）
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] The role of AUTS2 in synaptic formation and the cognitive brain functions2018
- Author(s)
  Kei Hori, Taku Nagai, Wei Shan, Mitsuyo Yamada, Reika Shiraishi, Asami Sakamoto, Kouta Kanno, Manabu Abe, Kiyofumi Yamada, Kenji Sakimura and Mikio Hoshino.
- Organizer
  第８回新潟大学脳研究所共同研究拠点国際シンポジウム（新潟大学脳研究所）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] 生後発達期大脳における自閉症感受性遺伝子AUTS2の生理機能の解析2017
- Author(s)
  堀啓、永井拓、Wei Shan、山田光代、白石玲花、菅野康太、坂本亜沙美、阿部学、崎村健司、山田清文、星野幹雄
- Organizer
  第40回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] 自閉症感受性遺伝子Auts2欠損による大脳神経細胞の過剰なシナプス形成の誘発2017
- Author(s)
  山田光代，堀啓，坂本亜沙美，阿部学，崎村健司，曽根雅紀，星野幹雄
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] 自閉症感受性遺伝子 AUTS2 のマウス海馬歯状回における機能解析2017
- Author(s)
  江草早紀，堀啓，坂本亜沙美，阿部学，崎村建司，郷康広，星野幹雄
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] 自閉症関連遺伝子Auts2のマウス大脳皮質形成における機能解析2017
- Author(s)
  嶋岡可純，堀啓，坂本亜沙美，阿部学，崎村健司，星野幹雄
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] 小脳プルキンエ細胞の発生制御における自閉症感受性遺伝子Auts2の生理機能の解析2016
- Author(s)
  Kei Hori, Ryo Aoki, Asami Sakamoto, Tomoo Owa, Satoshi MIyashita, Manabu Abe, Maya Yamazaki, Kenji Sakimura and Mikio Hoshino.
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K07021
[Presentation] 新規自閉症感受性遺伝子Auts2の分子機能の解析2013
- Author(s)
  堀啓
- Organizer
  第６回神経発生討論会
- Place of Presentation
  （独）理化学研究所脳科学総合センター（和光市）
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] 新規自閉症感受性遺伝子Auts2 の分子機能の解析2013
- Author(s)
  堀啓(代表)
- Organizer
  第6 回神経発生討論会
- Place of Presentation
  理化学研究所脳科学総合センター、和光市
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] Characterization of a novel Autism-related gene in the CNS development2012
- Author(s)
  堀啓(代表)
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] 新規自閉症感受性遺伝子Auts2の分子機能の解析2012
- Author(s)
  堀啓、西岡朋生、熊ノ郷晴子、貝渕弘三、星野幹雄
- Organizer
  第５回神経発生討論会
- Place of Presentation
  福井
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] 大脳皮質形成における新規自閉症関連遺伝子の分子機能の解明2012
- Author(s)
  堀啓
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場マリンメッセ（福岡）
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] 大脳皮質形成における新規自閉症関連遺伝子の分子機能の解明2012
- Author(s)
  堀啓(代表)
- Organizer
  第35回に本分子生物学会年会
- Place of Presentation
  福岡国際会議場マリンメッセ
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] Characterization of a novel Autism-related gene in the CNS development2012
- Author(s)
  Kei Hori
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23700406
[Presentation] 精神疾患病態の解明に向けた新規自閉症感受性遺伝子Auts2の分子機能解析
- Author(s)
  堀　啓
- Organizer
  国立精神・神経医療研究センター山梨大学合同シンポジウム（山梨大学）
- Place of Presentation
  山梨大学医学部
- Invited
- Data Source
  KAKENHI-PROJECT-25830030
[Presentation] 大脳皮質発生における新規自閉症感受性遺伝子の生理機能の解明
- Author(s)
  Kei Hori, Taku Nagai, Wei Shan, Asami Sakamoto, Shinichiro Taya, Manabu Abe, Maya Yamazaki, Keiko Nakao, Tomoki Nishioka, Kenji Sakimura, Kiyofumi Yamada, Kozo Kaibuchi and Mikio Hoshino.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜展示ホール1階
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25830030
[Presentation] Analysis of the function of a psychiatric disorder-related gene during development.
- Author(s)
  Mikio Hoshino, Kei Hori
- Organizer
  国立精神・神経医療研究センターマックスプランク研究所合同シンポジウム
- Place of Presentation
  ザ・プリンス箱根国際会議場
- Year and Date
  2014-11-05 – 2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-25830030
[Presentation] Analysis of the roles for the autism susceptibility candidate gene Auts2 in cerebellar development
- Author(s)
  Kei Hori, Ryo Aoki, Tomoo Owa, Miyashita Satoshi, Asami Sakamoto, Maya Yamazaki, Manabu Abe, Kenji Sakimura and Mikio Hoshino.
- Organizer
  第８回神経発生討論会
- Place of Presentation
  九州大学病院キャンパス内コラボステーションI
- Year and Date
  2015-03-19 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25830030

1. 星野幹雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hori Kei 堀 啓

HORI Kei 堀 啓

Research Projects

Research Products

Co-Researchers

シナプス発達に関わる自閉症関連遺伝子AUTS2の新規転写制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of AUTS2 in synaptic formation and the cognitive brain functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the role of autism susceptibility candidate gene Auts2 in brain development.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the molecular function of a novel autism susceptibility gene AUTS2 in cerebellar developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3?Ubiquitin Ligases and Intronic miR-1402018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuronal Migration and AUTS2 Syndrome2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycosphingolipid metabolic reprogramming drives neural differentiation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox92016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytoskeletal regulation of AUTS2 in neuronal migration and neuritogenesis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GABAergic neuron specification in the spinal cord, the cerebellum and the cochlear nucleus2012

Author(s)

Journal Title

Data Source

[Journal Article] GABAergic neuron specification in the spinal cord, the cerebellum, and the cochlear nucleus.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system.2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] 神経発達に関わる自閉症感受性遺伝子AUTS2の機能とその破綻メカニズムに関する研究2022

Author(s)

Organizer

Data Source

[Presentation] The role of AUTS2 in synaptic organization and the cognitive functions during postnatal brain development2018

Author(s)

Organizer

Data Source

[Presentation] Loss of Auts2 induces the defects of synaptic function and cognitive brain functions2018

Author(s)

Organizer

Data Source

Hori Kei 堀啓

HORI Kei 堀啓