NAKAYAMA KAZUHIKO 中山和彦

… Alternative Names

中山和彦ナカヤマカズヒコ

NAKAYAMA Kazuhiko 中山和彦

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Researcher Number	70584738
Other IDs
Affiliation (Current)	2025: 社会医療法人神鋼記念会(総合医学研究センター), 総合医学研究センター, 医長
Affiliation (based on the past Project Information) *help	2016 – 2018: 神戸大学, 医学研究科, 特命助教 2013: 神戸薬科大学, 薬学部, 助教 2012: 神戸薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy Except Principal Investigator Epidemiology and preventive medicine
Keywords	Principal Investigator アドレノメデュリン / 心房性ナトリウム利尿ペプチド / ブラジキニン / 糖尿病心筋症 / 糖尿病性心筋症 / 糖尿病性腎症 / エンドセリン変換酵素 Except Principal Investigator 心臓学校検診 / 分子疫学 / 先天性心疾患 … More / 分子疫学研究 / 学校心臓検診 / インドネシア / 肺高血圧症 / 心房中隔欠損症 Less

Molecular epidemiological study of atrial septal defect by introducing cardiac screening system for primary school in Indonesia
- Principal Investigator
  
  EMOTO Noriaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Kobe Pharmaceutical University
The investigation of peptidase inhibition toward diabetic nephropathy and cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Kazuhiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University

All 2017 2014 2013 2012

All Journal Article Presentation

[Journal Article] Endothelin-1 may play an important role in the Fontan circulation2017
- Author(s)
  Aoki Masaya、Hirono Keiichi、Higuma Tomonori、Suzuki Yoko、Nakayama Kazuhiko、Ichida Fukiko、Origasa Hideki、Nishida Naoki、Imura Johji、Emoto Noriaki、Yoshimura Naoki
- Journal Title
  
  Interactive CardioVascular and Thoracic Surgery
  
  Volume: 26 Issue: 3 Pages: 480-486
- DOI
  10.1093/icvts/ivx378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10726, KAKENHI-PROJECT-16H05827, KAKENHI-PROJECT-15K09685
[Journal Article] Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice : Potential roles of interleukin-6 and endothelin2014
- Author(s)
  Hung Tran Van, Noriaki Emoto, Nicolas Vignon-Zellweger, Kazuhiko Nakayama, Keiko Yagi, Yoko Suzuki, Ken-ichi Hirata
- Journal Title
  
  Life Sci
  
  Volume: (in press) Pages: 24-3205
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice: Potential roles of interleukin-6 and endothelin.2014
- Author(s)
  Van Hung T, Emoto N, Vignon-Zellweger N, Nakayama K, Yagi K, Suzuki Y, Hirata KI.
- Journal Title
  
  Life Sci.
  
  Volume: 印刷中 Issue: 2 Pages: 313-328
- DOI
  10.1016/j.lfs.2013.12.215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590123, KAKENHI-PROJECT-24790098
[Journal Article] エンドセリン受容体拮抗薬の臨床研究と今後の課題2013
- Author(s)
  中山和彦、江本憲明
- Journal Title
  
  心臓
  
  Volume: 45(12) Pages: 1503-1511
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] Noninvasive and Simple Assessment of Cardiac Output and Pulmonary Vascular Resistance With Whole-Body Impedance Cardiography Is Useful for Monitoring Patients With Pulmonary Hypertension2013
- Author(s)
  TaniguchiY, Emoto N, Miyagawa K, Nakayama K, Kinutani H, Tanaka H, Shinke T, Hirata KI
- Journal Title
  
  Circulation Journal
  
  Volume: 77 Pages: 2383-2389
- NAID
  10031191768
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] Endothelin-Converting Enzyme-1 Gene Ablation Attenuates Pulmonary Fibrosis via CGRP-cAMP/EPAC1 Pathway.2013
- Author(s)
  Hartopo AB, Emoto N, Vignon-Zellweger N, Suzuki Y, Yagi K, Nakayama K, Hirata K.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 48 Issue: 4 Pages: 465-476
- DOI
  10.1165/rcmb.2012-0354oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590123, KAKENHI-PROJECT-24790098
[Journal Article] Noninvasive and Simple Assessment of Cardiac Output and Pulmonary Vascular Resistance With Whole-Body Impedance Cardiography Is Useful for Monitoring Patients With Pulmonary Hypertension.2013
- Author(s)
  Taniguchi Y, Emoto N, Miyagawa K, Nakayama K, Kinutani H, Tanaka H, Shinke T, Hirata KI
- Journal Title
  
  Circulation Journal
  
  Volume: 77 Pages: 2383-2389
- NAID
  10031191768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] Endothelin-converting enzyme-1 gene ablation attenuates pulmonary fibrosis via CGRP-cAMP/EPAC1 pathway2013
- Author(s)
  Hartopo AB, Emoto N, Vignon-Zellweger N, Suzuki Y, Yagi K, Nakayama K, Hirata K
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 48 Pages: 465-76
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] ET-1 from endothelial cells is required for complete angiotensin II-induced cardiac fibrosis and hypertrophy2012
- Author(s)
  Adiarto S, Heiden S, Vignon-Zellweger N, Nakayama K, Yagi K, Yanagisawa M, Emoto N
- Journal Title
  
  Life Science
  
  Volume: 15 Pages: 651-657
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] Physiological relevance of hydrolysis of atrial natriuretic peptide by endothelin-converting enzyme-1.2012
- Author(s)
  Nakayama K, Emoto E, Suzuki Y, Vignon-Zellweger N, Yagi K, Hirata KI.
- Journal Title
  
  Kobe Journal of Medical Sciences
  
  Volume: 58(1)
- NAID
  110009591545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] Physiological relevance of hydrolysis of atrial natriuretic Peptide by endothelin-converting enzyme-1. Kobe2012
- Author(s)
  Nakayama K, Emoto N, SuzukiY, Vignon-Zellweger N, Yagi K, Hirata K
- Journal Title
  
  J Med Sci
  
  Volume: 58 Pages: 12-18
- Data Source
  KAKENHI-PROJECT-24790098
[Journal Article] ET-1 deletion from endothelial cells protects the kidney during the extension phase of ischemia/reperfusion injury2012
- Author(s)
  Arfian N, Emoto N, Vignon-Zellweger N, Nakayama K, Yagi K, Hirata K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 425 Pages: 443-449
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] エンドセリン変換酵素阻害によるカルシトニン遺伝子関連ペプチド賦活を介した糖尿病性腎症進展抑制効果の検討2014
- Author(s)
  中山和彦、亀田真吾、中原大介、鈴木陽子、岡野卓也、宮川一也、八木敬子、江本憲昭、平田健一
- Organizer
  第43回日本心脈管作動物質学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Endothelin-1 Derived Vascular Endothelial Cells Importance for Cardiac Remodeling Induced by Cryoinfarction2014
- Author(s)
  Muliawan HS, Nakayama K, Yagi K, Miyagawa K Suzuki Y, Satwiko MG, Nugroho DB, Jeffilano AB, Emoto N
- Organizer
  第43回日本心脈管作動物質学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Role of Vascular Endothelial Cells Endothelin-1 in Cardiac Remodeling Induced by Cryoinfarction2014
- Author(s)
  Muliawan HS, Emoto N, Nakayama K, Yagi K, Hirata K
- Organizer
  10th Asia Pacific Congress of Hypertension (APCH2014)
- Place of Presentation
  Pilippines, Cebu
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Endothelin-1 Derived Vascular Endothelial Cells Importance for Cardiac Remodeling Induced by Cryoinfarction2014
- Author(s)
  Muliawan HS, Nakayama K, Yagi K, Miyagawa K Suzuki Y, Satwiko MG, Nugroho DB, Jeffilano AB, Emoto N
- Organizer
  第43回日本心脈管作動物質学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] エンドセリン変換酵素阻害によるカルシトニン遺伝子関連ペプチド賦活を介した糖尿病性腎症進展抑制効果の検討2014
- Author(s)
  中山　和彦、亀田　真吾、中原　大介、鈴木　陽子、岡野　卓也、宮川　一也、八木　敬子、江本　憲昭、平田　健一
- Organizer
  第43回日本心脈管作動物質学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Role of Vascular Endothelial Cells Endothelin-1 in Cardiac Remodeling Induced by Cryoinfarction2014
- Author(s)
  Muliawan HS, Emoto N, Nakayama K, Yagi K, Hirata K
- Organizer
  10th Asia Pacific Congress of Hypertension (APCH2014)
- Place of Presentation
  Philippines Cebu
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] The Potentiation of Calcitonin Gene-related Peptide Pathway by Suppressing Endothelin Converting Enzyme Attenuates Kidney Dysfunction in Type 1 Diabetic Mice2014
- Author(s)
  Kazuhiko Nakayama , Yoko Suzuki, Takuya Okano, Kazuya Miyagawa, Keiko Yagi, Ken-ichi Hirata, Noriaki Emoto
- Organizer
  第78回日本循環器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Possible Involvement of Estrogen on Endothelin-1 Transgenic Mice in the Hypoxia Induced Pulmonary Arterial Hypertension Model2014
- Author(s)
  Muhammad G, N Emoto, K Nakayama, K Yagi, K Hirata
- Organizer
  第78回日本循環器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] The Potentiation of Calcitonin Gene-related Peptide Pathway by Suppressing Endothelin Converting Enzyme Attenuates Kidney Dysfunction in Type 1 Diabetic Mice.2014
- Author(s)
  Kazuhiko Nakayama , Yoko Suzuki, Takuya Okano, Kazuya Miyagawa, Keiko Yagi, Ken-ichi Hirata, Noriaki Emoto
- Organizer
  第78回日本循環器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Knockout of Endothelin-1 in Vascular Endothelial Cells Ameliorates Cardiac Remodelling induced by Cryoinfarction in Mice2014
- Author(s)
  Muliawan HS, Emoto N, Nakayama K, Yagi K, Hirata K
- Organizer
  第78回日本循環器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Distinct expression of endothelin-1 and endothelin converting enzyme-1 in the lung of patients undergoing right heart bypass surgery：A preliminary study2013
- Author(s)
  Naoki Yoshimura, Tomonori Higuma, Masaya Aoki, Yoshinori Doki, Hideyuki Nagkaoka, Keiichirou Ibuki, Sayaka Ozawa, Keiichi Hirono, Fukiko Ichida, Kazuhiko Nakayama, Takuya Okano, Noriaki Emoto
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Endothelin converting enzyme inhibition attenuates early albuminuria and late renal failure in streptozotocin induced diabetic mice2013
- Author(s)
  Kazuhiko Nakayama, Nicolas Vignon-Zellweger, Susi Heiden, Yoko Suzuki, Takuya Okano, Kazuya Miyagawa, Keiko Yagi, Masashi Yanagisawa, Noriaki Emoto
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] 肺動脈性肺高血圧症患者に対するエンドセリン受容体拮抗薬およびPDE5阻害剤追加併用療法の長期効果の検討2013
- Author(s)
  谷口悠、江本憲昭、絹谷洋人、中山和彦、新家俊郎、平田健一
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Focusing right heart function for predicting the oral medical efficacy in pulmonary hypertension2013
- Author(s)
  中山和彦、江本憲昭、谷口悠、絹谷洋人、鈴木陽子、新家俊郎、平田健一
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] 肺高血圧・肺線維症に対する新たなエンドセリン研究-エンドセリン変換酵素阻害の可能性-2013
- Author(s)
  中山和彦,　Anggoro B. Hartopo, 鈴木陽子, Sunu Budhi Raharjo, 江本憲昭
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Serum Endothelin-1 and big endothelin-1 in patients with chronic thromboembolic pulmonary hypertension can be markers to predict hemodynamics after balloon pulmonary angioplasty2013
- Author(s)
  Kazuya Miyagawa, Kazuhiko Nakayama, Yoko Suzuki, Yu Taniguchi, Hiroto Kinutani, Toshiro Shinke, Ken-ich Hirata, Noriaki Emoto
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Analysis of ET-1 system in mild and severe pulmonary arterial hypertension in mice2013
- Author(s)
  Hung Van Tran, Noriaki Emoto, Nicolas Vignon-Zellweger, Kazuhiko Nakayama, Keiko Yagi, Yoko Suzuki, Ken-ichi Hirata
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Distinct expression of endothelin-1 and endothelin converting enzyme-1 in the lung of patients undergoing right heart bypass surgery2013
- Author(s)
  Naoki Yoshimura, Tomonori Higuma, Masaya Aoki, Yoshinori Doki, Hideyuki Nagkaoka, Keiichirou Ibuki, Sayaka Ozawa, Keiichi Hirono, Fukiko Ichida, Kazuhiko Nakayama, Takuya Okano, Noriaki Emoto
- Organizer
  A preliminary study International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Impaired right heart function predicts the inefficacy of oral pulmonary vasodilators in the patients with pulmonary hypertension2013
- Author(s)
  Kazuhiko Nakayama, Noriaki Emoto, Yu Taniguchi, Hiroto Kinutani, Yoko Suzuki, Toshiro Shinke, Ken-ichi Hirata
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] 肺高血圧・肺線維症に対する新たなエンドセリン研究-エンドセリン変換酵素阻害の可能性2013
- Author(s)
  中山和彦, Anggoro B. Hartopo,鈴木陽子, Sunu Budhi Raharjo,江本憲昭
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Endothelial Cells-derived Endothelin-1 Exaggerates Kidney Fibrosis Through ETAR Activation in Renal Interstitial Cells2013
- Author(s)
  Nur Arfi an, Keiko Yagi, Kazuhiko Nakayama, Nicolas Vignon-Zellweger, Susi Heiden, Tran V. Hung, Hary S. Muliawan, Gahan Satwiko, Noriaki Emoto
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Absence of ETA receptors on podocytes is not antialbuminuric in diabetic mice2013
- Author(s)
  Nicolas Vignon-Zellweger, Susi Heiden, Kazuhiko Nakayama, Keiko Yagi, Marc Iglarz, Masashi Yanagisawa, Noriaki Emoto
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Harimurti Role of Bradykinin and Endothelin-Converting Enzyme-1 in Pulmonary Hypertension2013
- Author(s)
  Sunu B. Raharjo, Noriaki Emoto, Yoga Yuniadi, Kazuhiko Nakayama, Ganesja M
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] The therapeutic potential targeting endothelin converting enzyme towards pulmonary hypertension and fibrosis.2013
- Author(s)
  Kazuhiko Nakayama, Anggoro Budi Hartopo, Budhi Raharjo Sunu, Yoko Suzuki, Noriaki Emoto, Ken-ichi Hirata
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京ステーションコンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-24790098
[Presentation] Endothelin-Converting Enzyme-1 in Pulmonary Hypertension2013
- Author(s)
  Sunu B. Raharjo, Noriaki Emoto, Yoga Yuniadi, Kazuhiko Nakayama, Ganesja M. Harimurti
- Organizer
  International conference of Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790098

1. EMOTO Noriaki (30294218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. Niwa Koichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Dinarti Lucia Kris

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Anggrahini Dyah Wulan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Hartopo Anggoro Budi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 市田蕗子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 芳村直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 青木正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAYAMA KAZUHIKO 中山 和彦

中山 和彦 ナカヤマ カズヒコ

NAKAYAMA Kazuhiko 中山 和彦

Research Projects

Research Products

Co-Researchers

Molecular epidemiological study of atrial septal defect by introducing cardiac screening system for primary school in Indonesia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation of peptidase inhibition toward diabetic nephropathy and cardiomyopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Endothelin-1 may play an important role in the Fontan circulation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice : Potential roles of interleukin-6 and endothelin2014

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice: Potential roles of interleukin-6 and endothelin.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] エンドセリン受容体拮抗薬の臨床研究と今後の課題2013

Author(s)

Journal Title

Data Source

[Journal Article] Noninvasive and Simple Assessment of Cardiac Output and Pulmonary Vascular Resistance With Whole-Body Impedance Cardiography Is Useful for Monitoring Patients With Pulmonary Hypertension2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Endothelin-Converting Enzyme-1 Gene Ablation Attenuates Pulmonary Fibrosis via CGRP-cAMP/EPAC1 Pathway.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Noninvasive and Simple Assessment of Cardiac Output and Pulmonary Vascular Resistance With Whole-Body Impedance Cardiography Is Useful for Monitoring Patients With Pulmonary Hypertension.2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Endothelin-converting enzyme-1 gene ablation attenuates pulmonary fibrosis via CGRP-cAMP/EPAC1 pathway2013

Author(s)

Journal Title

Data Source

[Journal Article] ET-1 from endothelial cells is required for complete angiotensin II-induced cardiac fibrosis and hypertrophy2012

Author(s)

Journal Title

Data Source

[Journal Article] Physiological relevance of hydrolysis of atrial natriuretic peptide by endothelin-converting enzyme-1.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Physiological relevance of hydrolysis of atrial natriuretic Peptide by endothelin-converting enzyme-1. Kobe2012

Author(s)

Journal Title

Data Source

[Journal Article] ET-1 deletion from endothelial cells protects the kidney during the extension phase of ischemia/reperfusion injury2012

Author(s)

Journal Title

Data Source

[Presentation] エンドセリン変換酵素阻害によるカルシトニン遺伝子関連ペプチド賦活を介した糖尿病性腎症進展抑制効果の検討2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Endothelin-1 Derived Vascular Endothelial Cells Importance for Cardiac Remodeling Induced by Cryoinfarction2014

Author(s)

Organizer

NAKAYAMA KAZUHIKO 中山和彦

中山和彦ナカヤマカズヒコ

NAKAYAMA Kazuhiko 中山和彦