YONESHIGE Azusa 米重あづさ

… Alternative Names

Researcher Number	70586750
Other IDs
Affiliation (Current)	2022: 近畿大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022: 近畿大学, 医学部, 助教 2018 – 2020: 近畿大学, 医学部, 助教 2017 – 2018: 近畿大学, 医学部, 研究員 2014 – 2016: 近畿大学, 医学部, 助教 2011 – 2012: 東海大学, 糖鎖科学研究所, 特定研究員
Review Section/Research Field	Principal Investigator Experimental pathology / Laboratory animal science / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator 細胞死 / 神経変性 / 接着分子 / 緑内障 / 静的圧力 / 胚発生 / プロサポシン / サポシン / 細胞間接着分子 / 間質性肺炎 … More

神経接着分子に着目した新規頭蓋内輸送システムの確立と脳腫瘍創薬への展開Principal Investigator
- Principal Investigator
  
  米重あづさ
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kindai University
Molecular mechanism of neurodegeneration caused by modest static pressurePrincipal Investigator
- Principal Investigator
  
  米重あづさ
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kindai University
Pathogenic action of CADM1 shedding in neurodegenerationPrincipal Investigator
- Principal Investigator
  
  YONESHIGE Azusa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kindai University
Increased ectodomain shedding of cell adhesion molecule 1 in the lung of idiopathic interstitial pneumonia and in the pancreata of type 2 diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  YONESHIGE Azusa
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kinki University
Role of prosaposin in the mouse embryogenesisPrincipal Investigator
- Principal Investigator
  
  YONESHIGE Azusa
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University

All 2020 2018 2017 2016 2015 2014 2012 2011

All Journal Article Presentation Book

[Book] ライソゾーム病－最新の病態、診断、治療の進歩：サポシン欠損症2011
- Author(s)
  松田純子、米重あづさ
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-23700515
[Journal Article] Expression of cell adhesion molecule 1 in gastric neck and base glandular cells: Possible involvement in peritoneal dissemination of signet ring cells2018
- Author(s)
  Kimura R, Yoneshige A, Hagiyama M, Otani T, Inoue T, Shiraishi N, Yanagihara K, Wakayama T, Ito A.
- Journal Title
  
  Life Sciences
  
  Volume: 213 Pages: 206-213
- DOI
  10.1016/j.lfs.2018.10.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08680, KAKENHI-PROJECT-18K07049, KAKENHI-PROJECT-16K08723
[Journal Article] Structure-activity relationships of talaumidin derivatives: Their neurite-outgrowth promotion in vitro and optic nerve regeneration in vivo.2018
- Author(s)
  Ueno S, Yoneshige A, Koriyama Y, Hagiyama M, Shimomura Y, Ito A.
- Journal Title
  
  Invest. Ophthalmol. Vis. Sci.
  
  Volume: 59 Pages: 370-380
- DOI
  10.1167/iovs.17-22438
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08723, KAKENHI-PROJECT-16K11335, KAKENHI-PROJECT-17K08680, KAKENHI-PROJECT-16H01811
[Journal Article] Modest Static Pressure Can Cause Enteric Nerve Degeneration Through Ectodomain Shedding of Cell Adhesion Molecule 1.2017
- Author(s)
  Yoneshige A, Hagiyama M, Inoue T, Tanaka T, Ri A, Ito A
- Journal Title
  
  Molecular Neurobiology
  
  Volume: - Pages: 1-1
- DOI
  10.1007/s12035-016-0166-y
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15113, KAKENHI-PROJECT-15K19079, KAKENHI-PROJECT-15K01734, KAKENHI-PROJECT-16K08723, KAKENHI-PROJECT-17K08680
[Journal Article] Pathogenic Actions of Cell Adhesion Molecule 1 in Pulmonary Emphysema and Atopic Dermatitis.2015
- Author(s)
  Yoneshige A, Hagiyama M, Fujita M, Ito A
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: - Pages: 75-75
- DOI
  10.3389/fcell.2015.00075
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15113, KAKENHI-PROJECT-15K19079, KAKENHI-PROJECT-26860267
[Journal Article] The effects of chemically synthesized saposin C onglucosylceramide-β-glucosidase.2015
- Author(s)
  Yoneshige A, Muto M, Watanabe T, Hojo H, Matsuda J.
- Journal Title
  
  Clinical Biochemistry.
  
  Volume: 48 Pages: 1177-1180
- DOI
  10.1016/j.clinbiochem.2015.06.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23700515, KAKENHI-PROJECT-15K14465, KAKENHI-PROJECT-15J03876, KAKENHI-PROJECT-24590285
[Journal Article] Increased ectodomain shedding of cell adhesion molecule 1 as a cause of type II alveolar epithelial cell apoptosis in patients with idiopathic interstitial pneumonia.2015
- Author(s)
  2.Yoneshige, A., Hagiyama, M., Inoue, T., Mimae, T., Kato, T., Okada, M., Enoki, E., Ito, A.
- Journal Title
  
  Respir Res.
  
  Volume: 16 Pages: 90-90
- DOI
  10.1186/s12931-015-0255-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01734, KAKENHI-PROJECT-15K19079, KAKENHI-PROJECT-26860267
[Journal Article] The intracellular domain of cell adhesion molecule 1 is present in emphysematous lungs and induces lung epithelial cell apoptosis.2015
- Author(s)
  1.Hagiyama, M., Yoneshige, A., Inoue, T., Sato, Y., Mimae, T., Okada, M., Ito, A.
- Journal Title
  
  J Biomed Sci.
  
  Volume: 22 Pages: 67-67
- DOI
  10.1186/s12929-015-0173-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01734, KAKENHI-PROJECT-15K15113, KAKENHI-PROJECT-15K19079, KAKENHI-PROJECT-26860267
[Journal Article] Increased ectodomain shedding of cell adhesion molecule 1 from pancreatic islets in type 2 diabetic pancreata: correlation with hemoglobin A1c levels.2014
- Author(s)
  Inoue T, et al
- Journal Title
  
  PLoS One
  
  Volume: 9 Pages: 00-00
- DOI
  10.1371/journal.pone.0100988
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590492, KAKENHI-PROJECT-25860302, KAKENHI-PROJECT-26860267, KAKENHI-PROJECT-26860268
[Journal Article] Chemoenzymatic synthesis of hydrophobic glycoprotein: synthesis of saposin C carrying complex-type carbohydrate2012
- Author(s)
  Hojo H, Tanaka H, Hagiwara M, Asahina Y, Ueki A, Katayama H, Nakahara Y, Yoneshige A, Matsuda J, Ito Y, Nakahara Y
- Journal Title
  
  Journal of OrganicChemistry
  
  Volume: 77 Pages: 9437-9446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700515
[Journal Article] Synthesis of the sphingolipid activator protein, saposin C, using an azido-protected O-acyl isopeptide as an aggregation-disrupting element.2011
- Author(s)
  Hojo H, Katayama H, Tano C, Nakahara Y, Yoneshige A, Matsuda J, Sohma Y, Kiso Y, Nakahara Y
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 52 Pages: 635-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700515
[Journal Article] Synthesis of the sphingolipid activator protein, saposin C, using an azido-protected O-acyl isopeptide as an aggregation-disrupting element2011
- Author(s)
  Hojo H, Katayama H, Tano C, Nakahara Y, Yoneshige A, Matsuda J, Sohma Y, Kiso Y,Nakahara Y
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 52 Pages: 635-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] レーザーマイクロダイセクション法による視神経損傷マウス網膜神経節細胞層の単離と遺伝子発現解析.2020
- Author(s)
  米重あづさ、上野覚、萩山満、木村竜一朗、郡山恵樹、伊藤彰彦.
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07857
[Presentation] レーザーマイクロダイセクション法による視神経損傷マウス網膜神経節細胞層の単離と遺伝子発現解析2020
- Author(s)
  米重あづさ、上野覚、萩山満、木村竜一朗、郡山恵樹、伊藤彰彦
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07857
[Presentation] Enteric nerve degeneration in the colon dilated due to the luminal stenosis by cancer: involvement of CADM1/TSLC12016
- Author(s)
  Hagiyama M, Yoneshige A, Ito A.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08723
[Presentation] 上皮性癌腫の肉腫様変化では骨肉腫／骨芽細胞様表現型が出現する2015
- Author(s)
  米重あづさ, 村上哲平, 西村俊司, 伊藤彰彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860267
[Presentation] 接着分子cell adhesion molecule 1の細胞内断片による肺上皮アポトーシス誘導：肺気腫発症への関与2015
- Author(s)
  萩山満, 米重あづさ, 伊藤彰彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860267
[Presentation] 特発性間質性肺炎における肺上皮接着分子CADM1の発現異常2015
- Author(s)
  米重あづさ, 井上敬夫, 萩山満, 伊藤彰彦
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26860267
[Presentation] 2型糖尿病患者の膵島における接着分子CADM1は細胞外ドメインの切断が亢進している2015
- Author(s)
  井上敬夫, 萩山満, 米重あづさ, 榎木英介, 前西修, 筑後孝章, 木村雅友, 佐藤隆夫, 伊藤彰彦
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26860267
[Presentation] The effects of chemically synthesized saposin C on glucosylceramide-・-glucosidase2012
- Author(s)
  Yoneshige A, Mutou M, Watanabe T, Tano C, Hojo H, Matsuda J
- Organizer
  The 26th International Carbohydrate Symposium (ICS2012)
- Place of Presentation
  Hotel Melia Castilla (Spain)
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] The activity of chemically synthesized saposin C on glycosylceramide-β-glucosidase2012
- Author(s)
  Yoneshige A
- Organizer
  4th International Forum for Lysosomal Storage Disease & 17th Japanese Society for Lysosomal Disease
- Place of Presentation
  東京プリンスホテル
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] 化学合成サポシンCのグルコシルセラミド・グルコシダーゼ活性への影響2012
- Author(s)
  米重あづさ、北條裕信、武藤真長、松田純子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] プロサポシン強発現マウス胚組織の表現型解析2012
- Author(s)
  武藤真長、米重あづさ、昼沢良介、吉村真一、松田純子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] 化学合成サポシンCのグルコシルセラミドβグルコシダーゼ活性への影響2012
- Author(s)
  米重あづさ
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] Role of prosaposin in the embryogenesis of mouse2012
- Author(s)
  Mutou M, Yoneshige A, Watanabe T, Matsuda J
- Organizer
  The 26th International Carbohydrate Symposium (ICS2012)
- Place of Presentation
  Hotel Melia Castilla (Spain)
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] The effects of chemically synthesized saposin C on glucosylceramide-β-glucosidase2012
- Author(s)
  Yoneshige A
- Organizer
  26th International Carbohydrate Symposium
- Place of Presentation
  Hotel Melia Castilla (Spain)
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] The activity of chemically synthesized saposin C on glucosylceramide-・-glucosidase2012
- Author(s)
  Yoneshige A, Hojo H, Mutou M, Matsuda J
- Organizer
  第4回国際ライソゾーム病フォーラム
- Place of Presentation
  東京プリンスホテル
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] マウス胚発生におけるプロサポシンの役割2011
- Author(s)
  武藤真長、米重あづさ、渡邉昂、松田純子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] グルコシルセラミド-β-グルコシダーゼ活性に対する化学合成サポシンCの影響2011
- Author(s)
  米重あづさ、田野千春、北條裕信、松田純子
- Organizer
  第16回日本ライソゾーム病研究会
- Place of Presentation
  東京慈恵会医科大学（東京）
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] Prosaposin during the embryogenesis of mouse2011
- Author(s)
  Yoneshige A, Mutou M, Matsuda J
- Organizer
  The 31th Naito conference
- Place of Presentation
  Chateraise Gateaux Kingdom Sapporo
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] グルコシルセラミド-β-グルコシダーゼ活性に対する化学合成サポシンCの影響2011
- Author(s)
  米重あづさ、田野千春、北條裕信、松田純子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] Prosaposin during the embryogenesis of mouse.2011
- Author(s)
  Yoneshige A, Mutou M, Matsuda J
- Organizer
  The 31th Naito conference
- Place of Presentation
  Chateraise Gateaux Kingdom Sapporo, Hokkaido
- Data Source
  KAKENHI-PROJECT-23700515
[Presentation] マウス胚発生におけるプロサポシンの役割2011
- Author(s)
  武藤真長、米重あづさ、渡邉昂、松田純子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23700515

1. MATSUDA Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. KORIYAMA Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 伊藤彰彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
4. 萩山満

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
5. 井上敬夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 加藤貴史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YONESHIGE Azusa 米重 あづさ

米重 あづさ ヨネシゲ アヅサ

Research Projects

Research Products

Co-Researchers

神経接着分子に着目した新規頭蓋内輸送システムの確立と脳腫瘍創薬への展開Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of neurodegeneration caused by modest static pressurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenic action of CADM1 shedding in neurodegenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Increased ectodomain shedding of cell adhesion molecule 1 in the lung of idiopathic interstitial pneumonia and in the pancreata of type 2 diabetes mellitusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of prosaposin in the mouse embryogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ライソゾーム病－最新の病態、診断、治療の進歩：サポシン欠損症2011

Author(s)

Publisher

Data Source

[Journal Article] Expression of cell adhesion molecule 1 in gastric neck and base glandular cells: Possible involvement in peritoneal dissemination of signet ring cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure-activity relationships of talaumidin derivatives: Their neurite-outgrowth promotion in vitro and optic nerve regeneration in vivo.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modest Static Pressure Can Cause Enteric Nerve Degeneration Through Ectodomain Shedding of Cell Adhesion Molecule 1.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathogenic Actions of Cell Adhesion Molecule 1 in Pulmonary Emphysema and Atopic Dermatitis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effects of chemically synthesized saposin C onglucosylceramide-β-glucosidase.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased ectodomain shedding of cell adhesion molecule 1 as a cause of type II alveolar epithelial cell apoptosis in patients with idiopathic interstitial pneumonia.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The intracellular domain of cell adhesion molecule 1 is present in emphysematous lungs and induces lung epithelial cell apoptosis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased ectodomain shedding of cell adhesion molecule 1 from pancreatic islets in type 2 diabetic pancreata: correlation with hemoglobin A1c levels.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemoenzymatic synthesis of hydrophobic glycoprotein: synthesis of saposin C carrying complex-type carbohydrate2012

YONESHIGE Azusa 米重あづさ

米重あづさヨネシゲアヅサ