kimura hiroaki 木村博昭

… Alternative Names

KIMURA HIROAKI 木村博昭

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Researcher Number	70593622
Other IDs	https://orcid.org/0000-0002-7441-0382
Affiliation (Current)	2024: 九州医療科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 九州保健福祉大学, 薬学部, 教授 2011 – 2021: 自治医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Endocrinology / Basic Section 48040:Medical biochemistry-related / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Cardiovascular medicine / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 53020:Cardiology-related / Endocrinology
Keywords	Principal Investigator マクロファージ / 免疫プロテアソーム / 炎症 / LMP7 / 脂肪細胞 / 脂肪肝 / メタボリック症候群 / 肥満 / STAT6 / LMP7欠損 … More / M2マクロファージ分化 / 脂肪蓄積 / 脂肪性肝炎 / LMP2 / 肝機能 / 非アルコール性脂肪性肝炎 / NASH / 脂質代謝 / 脂肪細胞分化 / 糖代謝 / 糖尿病 / 脂肪 / M2 / 分化 / diabetes / inflammation / macrophages / obeisty / immunoproteasome / 動脈硬化 / 内臓脂肪 / メタボリックシンドローム / 高脂肪食 … More Except Principal Investigator インフラマソーム / 炎症 / ユビキチン / 細胞死 / マクロファージ / 自然免疫 / 免疫 / タンパク質修飾 / 心血管病 / 炎症反応 / サイトカイン / 脂質結晶 / インターロイキン / 飽和脂肪酸 / カスパーゼ1 / Interleukin-1 / 動脈硬化 / カスパーゼ / コレステロール結晶 / 好中球 / タンパク質分解 / 免疫学 / ユビキチン化 / ユビキチン修飾 / 血栓症 / 生活習慣病 Less

Analysis of differentiation capacity mechanism and functional evaluation of immunoproteasome-deficient M2 macrophagesPrincipal Investigator
- Principal Investigator
  
  木村博昭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kyushu University of Health and Welfare
Role of the immunoproteasome in nonalcoholic steatohepatitisPrincipal Investigator
- Principal Investigator
  
  木村博昭
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyushu University of Health and Welfare
Role of ARIH2 in the inflammasome-related cardiovascular disease
- Principal Investigator
  
  Takahashi Masafumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
Neutrophils in inflammatory response induced by lipid crystals
- Principal Investigator
  
  Karasawa Tadayoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Jichi Medical University
Study of the role of the immunoproteasome in glucose- or lipid-metabolismPrincipal Investigator
- Principal Investigator
  
  KIMURA HIROAKI
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kyushu University of Health and Welfare
  Jichi Medical University
Role of adapter molecule ASC independent of inflammasome
- Principal Investigator
  
  Kawanishi Fumitake
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Toyama Prefectural University
The study about inflammasome regulation system by protein degradation
- Principal Investigator
  
  Kawashima Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Teikyo University
Molecular mechanisms underlying inflammasome-mediated cardiovascular disease
- Principal Investigator
  
  Takahashi Masafumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Jichi Medical University
Analysis of the role of the immunoproteasome in obesity and diabetesPrincipal Investigator
- Principal Investigator
  
  Kimura Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Jichi Medical University
Role of the immunoproteasome in the pathogenesis of metabolic syndromePrincipal Investigator
- Principal Investigator
  
  KIMURA HIROAKI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Jichi Medical University

All 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors2023
- Author(s)
  Inaba Hidefumi、Morita Shuhei、Kosugi Daisuke、Asai Yuki、Kaido Yosuke、Ito Saya、Hirobata Tomonao、Inoue Gen、Yamamoto Yuki、Jinnin Masatoshi、Kimura Hiroaki、Ota Masao、Okudaira Yuko、Nakatani Hiroyasu、Kobayashi Tomoko、Iwama Shintaro、Arima Hiroshi、Matsuoka Takaaki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14
- DOI
  10.3389/fimmu.2023.1165004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07365
[Journal Article] Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors2022
- Author(s)
  Inaba Hidefumi、Kaido Yosuke、Ito Saya、Hirobata Tomonao、Inoue Gen、Sugita Takakazu、Yamamoto Yuki、Jinnin Masatoshi、Kimura Hiroaki、Kobayashi Tomoko、Iwama Shintaro、Arima Hiroshi、Matsuoka Takaaki
- Journal Title
  
  Endocrinology and Metabolism
  
  Volume: 37 Issue: 1 Pages: 84-95
- DOI
  10.3803/enm.2021.1282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-21K08544, KAKENHI-PROJECT-20K17541
[Journal Article] Crucial role of NLRP3 inflammasome in a murine model of Kawasaki disease.2020
- Author(s)
  4)Anzai F, Watanabe S, Kimura H, Kamata R, Karasawa T, Komada T, Nakamura J, Nagi-Miura N, Ohno N, Takeishi Y, Takahashi M
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 138 Pages: 185-196
- DOI
  10.1016/j.yjmcc.2019.11.158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-19K08523, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-19K08916
[Journal Article] NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury2020
- Author(s)
  Ito Homare、Kimura Hiroaki、Karasawa Tadayoshi、Hisata Shu、Sadatomo Ai、Inoue Yoshiyuki、Yamada Naoya、Aizawa Emi、Hishida Erika、Kamata Ryo、Komada Takanori、Watanabe Sachiko、Kasahara Tadashi、Suzuki Takuji、Horie Hisanaga、Kitayama Joji、Sata Naohiro、Yamaji-Kegan Kazuyo、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 205 Issue: 5 Pages: 1393-1405
- DOI
  10.4049/jimmunol.2000217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K08630, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-20K17629, KAKENHI-PROJECT-17K09889
[Journal Article] GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition2020
- Author(s)
  Aizawa Emi、Karasawa Tadayoshi、Watanabe Sachiko、Komada Takanori、Kimura Hiroaki、Kamata Ryo、Ito Homare、Hishida Erika、Yamada Naoya、Kasahara Tadashi、Mori Yoshiyuki、Takahashi Masafumi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 5 Pages: 101070-101070
- DOI
  10.1016/j.isci.2020.101070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-20K17290
[Journal Article] GSDME-dependentincomplete pyroptosis permits selective IL-1α release under caspase-1 inhibition2020
- Author(s)
  Aizawa E, Karasawa T, Watanabe S, Komada T, Kimura H, Kamata R, ItoH, Hishida E, Yamada N, Kasahara T, Mori Y, Takahashi M
- Journal Title
  
  iScience
  
  Volume: －
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Deletion of inflammasome adaptor protein ASC enhances functional recovery after spinal cord injury in mice2020
- Author(s)
  Shiraishi Y, Kimura A, Kimura H, Ohmori T, Takahashi M, Takeshita K
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: potential role of ferroptosis.2020
- Author(s)
  3)Yamada N, Karasawa T, Wakiya T, Sadatomo A, Ito H, Kamata R, Watanabe S, Komada T, Kimura H, Sanada Y, Sakuma Y, Mizuta K, Sata N, Takahashi M
- Journal Title
  
  Am J Transplant
  
  Volume: - Issue: 6 Pages: 1606-1618
- DOI
  10.1111/ajt.15773
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K16329, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-20K07365
[Journal Article] ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome2020
- Author(s)
  Watanabe Sachiko、Usui-Kawanishi Fumitake、Komada Takanori、Karasawa Tadayoshi、Kamata Ryo、Yamada Naoya、Kimura Hiroaki、Dezaki Katsuya、Ohmori Tsukasa、Takahashi Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 2 Pages: 125-132
- DOI
  10.1016/j.bbrc.2020.07.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K08524, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08370
[Journal Article] Deletion of inflammasome adaptor protein ASC enhances functional recovery after spinal cord injury in mice2020
- Author(s)
  Shiraishi Yasuyuki、Kimura Atsushi、Kimura Hiroaki、Ohmori Tsukasa、Takahashi Masafumi、Takeshita Katsushi
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 20 Issue: 3 Pages: 30124-30124
- DOI
  10.1016/j.jos.2020.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08370, KAKENHI-PROJECT-20K07365
[Journal Article] Glucose regulates hypoxia-induced NLRP3 inflammasome activation in macrophages.2020
- Author(s)
  1)Watanabe S, Usui-Kawanishi F, Karasawa, Kimura H, Kamata R, Inoue, Mise N, Kasahara T, Takahashi M
- Journal Title
  
  J Cell Physiol
  
  Volume: - Issue: 10 Pages: 7554-7566
- DOI
  10.1002/jcp.29659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290
[Journal Article] Immnoproteasome2020
- Author(s)
  Kimura H
- Journal Title
  
  eLS
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09889
[Journal Article] Immunoproteasome2020
- Author(s)
  Kimura Hiroaki
- Journal Title
  
  eLS (encyclopedia of Life Sciences)
  
  Volume: - Pages: 1-9
- DOI
  10.1002/9780470015902.a0026244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-17K09889
[Journal Article] Ferroptosis driven by radical oxidation of n-6 fatty acids mediates acetaminophen-induced acute liver failure.2020
- Author(s)
  2)Yamada N, Karasawa T, Kimura H, Watanabe S, Komada T, Kamata R, Sampilvanjil A, Ito J, Nakagawa K, Kuwata H, Hara S, Sakuma Y, Sata N, Takahashi M
- Journal Title
  
  Cell Death Dis
  
  Volume: 11 Issue: 2 Pages: 144-144
- DOI
  10.1038/s41419-020-2334-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-19K07087, KAKENHI-PROJECT-19H03375, KAKENHI-PROJECT-19K21319
[Journal Article] Glucose regulates hypoxia-induced NLRP3inflammasome activation in macrophages2020
- Author(s)
  Watanabe S, Usui-Kawanishi F, Karasawa T, Kimura H, Kamata R, InoueY, Mise N, Kasahara T, Takahashi M
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: －
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Crucial role of NLRP3 inflammasome in the development of peritoneal dialysis-related peritoneal fibrosis.2019
- Author(s)
  6)Hishida E, Ito H, Komada T, Karasawa T, Kimura H, Watanabe S, Kamata R, Aizawa E, Kasahara T, Morishita Y, AkimotoT, Nagata D, Takahashi M
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 10363-10363
- DOI
  10.1038/s41598-019-46504-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K15900, KAKENHI-PROJECT-18K16329, KAKENHI-PROJECT-19K21319
[Journal Article] Role of TLR5 in inflammation and tissue damage after intestinal ischemia-reperfusion injury.2019
- Author(s)
  7)Ito H, Sadatomo A, Inoue Y, Yamada N, Aizawa E, Hishida E, Kamata R, Karasawa T, Kimura H, Watanabe S, Komada T, Horie H, Kitagawa J, Sata N, Takahashi M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 519 Issue: 1 Pages: 15-22
- DOI
  10.1016/j.bbrc.2019.08.083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K15900, KAKENHI-PROJECT-18K16329, KAKENHI-PROJECT-19K21319
[Journal Article] Inflammasome-independent and atypical processing of IL-1β contributes to acid aspiration-induced acute lung injury.2019
- Author(s)
  5)Mizushina Y, Karasawa T, Aizawa K, Kimura H, Watanabe S, Kamata R, Komada T, Mato N, Kasahara T, Koyama S, Bando M, Hagiwara K, Takahashi M
- Journal Title
  
  J Immunol
  
  Volume: 203 Issue: 1 Pages: 236-246
- DOI
  10.4049/jimmunol.1900168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K15900, KAKENHI-PROJECT-19K21319
[Journal Article] Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease.2018
- Author(s)
  Nakamura J, Watanabe S, Kimura H, Kobayashi M, Karasawa T, Kamata R, Usui-Kawanishi F, Sadatomo A, Mizukami H, Nagi-Miura N, Ohno N, Kasahara T, Minota S, Takahashi M.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 7601-7601
- DOI
  10.1038/s41598-018-25856-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485
[Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018
- Author(s)
  Karasawa Tadayoshi、Kawashima Akira、Usui-Kawanishi Fumitake、Watanabe Sachiko、Kimura Hiroaki、Kamata Ryo、Shirasuna Koumei、Koyama Yutaro、Sato-Tomita Ayana、Matsuzaka Takashi、Tomoda Hiroshi、Park Sam-Yong、Shibayama Naoya、Shimano Hitoshi、Kasahara Tadashi、Takahashi Masafumi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 4 Pages: 744-756
- DOI
  10.1161/atvbaha.117.310581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-17K09889, KAKENHI-PUBLICLY-16H01395, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16K09808, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia?Reperfusion Injury2017
- Author(s)
  Sadatomo Ai、Inoue Yoshiyuki、Ito Homare、Karasawa Tadayoshi、Kimura Hiroaki、Watanabe Sachiko、Mizushina Yoshiko、Nakamura Jun、Kamata Ryo、Kasahara Tadashi、Horie Hisanaga、Sata Naohiro、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 9 Pages: 3306-3315
- DOI
  10.4049/jimmunol.1700717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] 医学のあゆみ（甲状腺疾患のすべて）2017
- Author(s)
  木村博昭
- Journal Title
  
  医学のあゆみ
  
  Volume: 260 Pages: 729-734
- Data Source
  KAKENHI-PROJECT-17K09889
[Journal Article] The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction2017
- Author(s)
  Kobayashi Motoi、Usui-Kawanishi Fumitake、Karasawa Tadayoshi、Kimura Hiroaki、Watanabe Sachiko、Mise Nathan、Kayama Fujio、Kasahara Tadashi、Hasebe Naoyuki、Takahashi Masafumi
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: 176676-176676
- DOI
  10.1371/journal.pone.0176676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K06912, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages2017
- Author(s)
  Kawashima Akira、Karasawa Tadayoshi、Tago Kenji、Kimura Hiroaki、Kamata Ryo、Usui-Kawanishi Fumitake、Watanabe Sachiko、Ohta Satoshi、Funakoshi-Tago Megumi、Yanagisawa Ken、Kasahara Tadashi、Suzuki Koichi、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 10 Pages: 3614-3622
- DOI
  10.4049/jimmunol.1700184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K09808, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-17K08641, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] Caspse-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity.2016
- Author(s)
  Kimura H, Karasawa T, Usui F, Kawashima A, Endo Y, Kobayashi M, Sadatomo A, Nakamura J, Iwasaki Y, T Yada,Tsutsui H, Kasahara T, Takahashi M.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 311 Issue: 5 Pages: 881-890
- DOI
  10.1152/ajpendo.00174.2016
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K19544
[Journal Article] NLRP3 reduces macrophage interleukin-10 production and enhances the susceptibility to doxorubicin-induced cardiotoxicity.2016
- Author(s)
  Kobayashi M, Usui F, Karasawa T, Kawashima A, Kimura H, Mizushina Y, Shirasuna K, Mizukami H, Kasahara T, Hasebe N, Takahashi M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 26489-26489
- DOI
  10.1038/srep26489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K19544
[Journal Article] NLRP3 deficiency improves angiotensin II-induced hypertension but not fetal growth restriction during pregnancy.2015
- Author(s)
  Shirasuna K, Karasawa T, Usui F, Kobayashi M, Komada T, Kimura A, Ohkuchi A, Taniguchi S, Takahashi M.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 11 Pages: 4281-4292
- DOI
  10.1210/en.2015-1408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-24592482, KAKENHI-PROJECT-26461386
[Journal Article] Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model.2015
- Author(s)
  Gautam M., Fujita D., Kimura K., Ichikawa H., Izawa A., Hirose M., Kashihara T., Yamada M., Takahashi M., Ikeda U., Shiba Y.
- Journal Title
  
  Journal of molecular and cellular cardiology
  
  Volume: 81 Pages: 139-149
- DOI
  10.1016/j.yjmcc.2015.02.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860145, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461062, KAKENHI-PROJECT-26293182
[Journal Article] Role of NLRP3 inflammasomes for rhabdomyolysis-induced acute kidney injury.2015
- Author(s)
  Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10901-10901
- DOI
  10.1038/srep10901
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β2015
- Author(s)
  Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 8 Pages: 5065-5077
- DOI
  10.1074/jbc.m114.603217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146
[Journal Article] Immunoproteasome LMP7 deficiency improves obesity and metabolic disorders.2015
- Author(s)
  Kimura H, Usui F, Karasawa T, Kawashima A, Shirasuna K, Inoue Y, Komada T, Kobayashi M, Mizushina Y, Kasahara T, Suzuki K, Iwasaki Y, Yada T, Caturegli P, Takahashi M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 15883-15883
- DOI
  10.1038/srep15883
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] Oligomerized CARD16 Promotes Caspase-1 Assembly and IL-1β Processing2015
- Author(s)
  Tadayoshi Karasawa, Akira Kawashima, Fumitake Usui, Hiroaki Kimura, Koumei Shirasuna, Yoshiyuki Inoue, Takanori Komada, Motoi Kobayashi, Yoshiko Mizushina, Junji Sagara, Masafumi Takahashi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 5 Issue: 1 Pages: 348-356
- DOI
  10.1016/j.fob.2015.04.011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24890217, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] New insights into the function of the immunoproteasome in immune and non-immune cells.2015
- Author(s)
  Kimura H, Caturegli P, Takahashi M, Suzuki K.
- Journal Title
  
  Journal of Immunology Research
  
  Volume: 2015 Pages: 541984-541984
- DOI
  10.1155/2015/541984
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.2014
- Author(s)
  Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M.
- Journal Title
  
  Nanotoxicology
  
  Volume: 11 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461386
[Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC2014
- Author(s)
  Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
- Journal Title
  
  Nanotoxicology
  
  Volume: 11 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591359
[Journal Article] Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages2014
- Author(s)
  Hara K, Shirasuna K, Usui F, Karasawa T, Mizushina Y, Kimura H, Kawashima A, Ohkuchi A, Matsuyama S, Kimura K, Takahashi M
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: 1-17
- DOI
  10.1371/journal.pone.0113974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-26461386
[Journal Article] Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm2014
- Author(s)
  Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 35 Issue: 1 Pages: 127-136
- DOI
  10.1161/atvbaha.114.303763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26670621
[Journal Article] NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes.2014
- Author(s)
  Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki, Nishimura S, Sagara J, Noda T, IwakuraY, Hiroko Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M.
- Journal Title
  
  J Immunol
  
  Volume: 192(9) Issue: 9 Pages: 4342-4351
- DOI
  10.4049/jimmunol.1302039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-26461386
[Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.2014
- Author(s)
  Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
- Journal Title
  
  Nanotoxicology
  
  Volume: 11 Issue: 5 Pages: 1-14
- DOI
  10.3109/17435390.2014.956156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146
[Journal Article] ASC in Renal Collecting Duct Epithelial Cells Contributes to Inflammation and Injury after Unilateral Ureteral Obstruction2014
- Author(s)
  Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
- Journal Title
  
  American Journal of Pathology
  
  Volume: 184(5) Issue: 5 Pages: 1287-1298
- DOI
  10.1016/j.ajpath.2014.01.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222
[Journal Article] 肉芽腫　-免疫を中心に-2013
- Author(s)
  木村博昭, 鈴木幸一
- Journal Title
  
  Monthly Book Derma
  
  Volume: 204 Pages: 8-14
- Data Source
  KAKENHI-PROJECT-23591359
[Journal Article] 橋本病の病因2013
- Author(s)
  鈴木幸一, 木村博昭
- Journal Title
  
  日本甲状腺学会雑誌
  
  Volume: 4 Pages: 14-18
- Data Source
  KAKENHI-PROJECT-23591359
[Journal Article] Hürthle cells predict hypothyroidism in interferon-γ transgenic mice of different genetic backgrounds.2012
- Author(s)
  Iwama S, De Remigis A, Bishop JA, Kimura HJ, Caturegli P.
- Journal Title
  
  Endocrinology
  
  Volume: 153 Issue: 8 Pages: 4059-4066
- DOI
  10.1210/en.2012-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591359
[Journal Article] Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.2012
- Author(s)
  Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S, Takahashi M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 425 Issue: 2 Pages: 162-168
- DOI
  10.1016/j.bbrc.2012.07.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24591419, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-24890217, KAKENHI-PUBLICLY-24117709
[Journal Article] Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice.2012
- Author(s)
  Usui F, Kimura H, Ohshiro T, Tatsumi K, Kawashima A, Nishiyama A, Iwakura Y, Ishibashi S, Takahashi M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 420 Pages: 72-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591359
[Journal Article] Inhibition of Fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development.2011
- Author(s)
  Xiao Z, Mohamood AS, Uddin S, Gutfreund R, Nakata C, Marshall A, Kimura H, Caturegli P, Womer KL, Huang Y, Jie C, Chakravarti S, Schneck JP, Yagita H, Hamad AR.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 178 Pages: 725-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] CAWS誘導川崎病様マウス血管炎におけるインフラマソームの役割2020
- Author(s)
  1)木村博昭,安齋文弥,唐澤直義,駒田敬則,鎌田諒,笠原忠,三浦典子,大野尚仁,高橋将文
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] アセトアミノフェン急性肝不全におけるFerroptosisの分子機構2019
- Author(s)
  山田直也、唐澤直義、駒田敬則、木村博昭、伊藤準哉、仲川清隆、桑田浩、原俊太郎、佐久間康成、佐田尚宏、高橋将文
- Organizer
  第33回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 脂肪細胞分化における免疫プロテアソームの役割2019
- Author(s)
  2)木村博昭，唐澤直義，駒田敬則，鎌田諒，笠原忠，高橋将文
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 脂肪細胞分化におけるLMP7の役割．2018
- Author(s)
  木村博昭、唐澤直義、渡邊幸子、鎌田諒、駒田敬則、笠原忠、高橋将文．
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 甲状腺細胞の自然免疫活性化が誘導する細胞死機構の解明2018
- Author(s)
  川島晃、Yuqian、Chen Fei、木村博昭、石藤雄子、鈴木幸一
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09808
[Presentation] CAWS誘導川崎病様マウス血管炎のIL-10による病態抑制効果2018
- Author(s)
  木村博昭, 中村潤, 渡邊幸子, 唐澤直義, 鎌田涼, 笠原忠, 三浦典子, 大野尚仁, 高橋将文
- Organizer
  日本薬学会第１３８年会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 脂肪細胞分化における免疫プロテアソームの役割2018
- Author(s)
  木村博昭、唐澤直義、渡邊幸子、鎌田涼、鈴木幸一、高橋将文
- Organizer
  第91回日本内分泌学会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 低酸素刺激によるNLRP3インフラマソーム活性化機構の解明2018
- Author(s)
  渡邊幸子、河西文武、木村博昭、唐澤直義、鎌田諒、高橋将文．
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 飽和脂肪酸の結晶形成を介した炎症惹起機構の解明2018
- Author(s)
  唐澤直義, 渡邊幸子, 木村博昭, 松坂賢, 島野仁, 高橋将文
- Organizer
  第55回　日本臨床分子医学会　学術集会
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] 腸管虚血再灌流障害におけるNLRP3インフラマソームの役割の解明．2018
- Author(s)
  伊藤誉、佐田友藍、井上賢之、鎌田諒、渡邊幸子、唐澤直義、木村博昭、佐田尚宏、高橋将文．
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 脂肪細胞分化におけるLMP7の役割2018
- Author(s)
  木村博昭、唐澤直義、渡邊幸子、鎌田涼、駒田敬則、笠原忠、高橋将文
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 高脂肪食による肥満性炎症におけるCaspase-1の役割2017
- Author(s)
  木村博昭、唐澤直義、笠原忠、高橋将文
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] ドキソルビシン心筋傷害におけるインフラマソーム構成分子NLRP3の役割．2017
- Author(s)
  高橋将文、小林基、唐澤直義、渡邊幸子、木村博昭．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] Contribution of the immunoproteasome to the inflammatory phenotype observed in obese mice.2017
- Author(s)
  Kimura H, Karasawa T, Watanabe S, Suzuki K, Caturegli P, Takahashi M.
- Organizer
  IMMUNOLOGY2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] New insights into the role of the immunoproteasome in inflammatory diseases.2017
- Author(s)
  Hiroaki Kimura, Tadayoshi Karasawa, Tadasahi Kasahara, Patrizio Caturegli, Masafumi Takahashi.
- Organizer
  第19回武田振興財団生命科学シンポジウム（慢性炎症：機序と制御）
- Place of Presentation
  武田薬品研修所（大阪府吹田市）
- Year and Date
  2017-01-20
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] Contribution of the immunoproteasome to the inflammatory phenotype observed in obese mice2017
- Author(s)
  Hiroaki Kimura, Tadayoshi Karasawa, Sachiko Watanabe, Koichi Suzuki, Patrizio Caturegli, Masafumi Takahashi
- Organizer
  Immunology 2017 (AAI)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 飽和脂肪酸は結晶形成を介して好中球浸潤を誘導する．2017
- Author(s)
  唐澤直義、渡邊幸子、木村博昭、高橋将文．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食誘導による肥満性炎症におけるCaspase-1の役割2017
- Author(s)
  木村博昭, 唐澤直義, 渡邊幸子, 笠原忠, 高橋将文
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 高脂肪食による肥満性炎症におけるCaspase-1の役割2017
- Author(s)
  木村博昭, 唐澤直義, 岩崎有作, 矢田俊彦, 高橋将文
- Organizer
  第９０回日本内分泌学会
- Data Source
  KAKENHI-PROJECT-17K09889
[Presentation] 高脂肪食誘導による肥満性炎症におけるCaspase-1の役割．2017
- Author(s)
  木村博昭、唐澤直義、渡邊幸子、笠原忠、高橋将文．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 肝虚血再灌流障害におけるインフラマソーム非依存性IL-1β産生機構の解明．2017
- Author(s)
  佐田友藍、井上賢之、渡邊幸子、唐澤直義、木村博昭、佐田尚宏、高橋将文．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食による肥満性炎症におけるCaspase-1の役割．2017
- Author(s)
  木村博昭、唐澤直義、岩崎有作、矢田俊彦、高橋将文．
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食誘導型肥満における免疫プロテアソーム（LMP7）の役割．2016
- Author(s)
  木村博昭、唐澤直義、川島晃、臼井文武、笠原忠、鈴木幸一、高橋将文．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析．2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食による肥満・メタボリック病態における免疫プロテアソーム欠損の有益な効果2016
- Author(s)
  木村博昭　臼井文武　唐澤直義　川島晃　笠原忠　鈴木幸一　岩崎有作　矢田俊彦　高橋将文
- Organizer
  高脂肪食による肥満・メタボリック病態における免疫プロテアソーム欠損の有益な効果
- Place of Presentation
  京都国際会館（京都）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割．2016
- Author(s)
  高橋将文、駒田敬則、臼井文武、唐澤直義、川島晃、木村博昭．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] メタボリック病態における免疫プロテアソーム欠損の有益な効果．2016
- Author(s)
  木村博昭、臼井文武、唐澤直義、川島晃、笠原忠、鈴木幸一、岩﨑有作、矢田俊彦、高橋将文．
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文
- Organizer
  第3７回日本炎症・再生医学会
- Place of Presentation
  みやこメッセ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 高脂肪食誘導型肥満における免疫プロテアソーム(LMP7)の役割2016
- Author(s)
  木村博昭　唐澤直義　川島晃　臼井文武　笠原忠　鈴木幸一　高橋将文
- Organizer
  第3７回日本炎症・再生医学会
- Place of Presentation
  みやこメッセ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 飽和脂肪酸によるインフラマソーム活性化機構の解析．2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文．
- Organizer
  第48回日本動脈硬化学会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2016
- Author(s)
  高橋将文、駒田敬則、臼井文武、唐澤直義、川島晃、木村博昭
- Organizer
  第3７回日本炎症・再生医学会
- Place of Presentation
  みやこメッセ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、駒田敬則、唐澤直義、川島晃、木村博昭、武藤重明、長田太助、高橋将文
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 動脈硬化および大動脈瘤形成におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、谷口俊一郎、高橋将文．
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センター（東京都台東区）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  高橋将文、駒田敬則、臼井文武、川島晃、唐澤直義、木村博昭．
- Organizer
  心血管抗加齢研究会2015
- Place of Presentation
  梅田スカイビル（大阪市北区）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、駒田敬則、唐澤直義、川島晃、木村博昭、武藤重明、長田太助、高橋将文．
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂質代謝異常におけるASCの役割2015
- Author(s)
  唐澤直義、木村博昭、臼井文武、川島晃、高橋将文．
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂質代謝異常におけるASCの役割2015
- Author(s)
  唐澤直義、木村博昭、臼井文武、川島晃、高橋将文
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 免疫プロテアソーム欠損は高脂肪食による肥満を抑制する2015
- Author(s)
  木村博昭、臼井文武、唐澤直義、川島晃、笠原忠、岩崎有作、矢田俊彦、高橋将文
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] Reevaluation of mouse models of Hashimoto’s thyroiditis2012
- Author(s)
  H. Kimura, K. Suzuki, S. Iwama, N.R. Rose, M. Takahashi, P. Caturegli.
- Organizer
  第53回日本甲状腺学会、橋本病100周年記念国際シンポジウムI「甲状腺と自己免疫」
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 自己免疫性下垂体炎の動物モデル2012
- Author(s)
  木村博昭、Shey-Cherng Tzou、Giovanni Pinna、Isabella Lupi、Melissa Landek-Salgado、高橋将文、Noel R. Rose、Patrizio Caturegli
- Organizer
  第39回日本神経内分泌学会
- Place of Presentation
  北九州市
- Invited
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 自己免疫性甲状腺炎の病態における免疫プロテアソームの関与2012
- Author(s)
  木村博昭、鈴木幸一、高橋将文、Patrizio Caturegli
- Organizer
  第85回日本内分泌学会
- Place of Presentation
  名古屋市
- Invited
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 甲状腺特異的IFNγトランスジェニックマウスのHurthle細胞の出現と甲状腺機能低下は相関する2012
- Author(s)
  木村博昭、岩間信太郎、鈴木幸一、高橋将文、Patrizio Cturegli
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 甲状腺特異的IFNgトランスジェニックマウスの慢性炎症発現はC57BL/6系統群に限られ、MHCハプロタイプに依存しない。2011
- Author(s)
  木村博昭、鈴木幸一、高橋将文、Patrizio Caturegli
- Organizer
  第54回日本甲状腺学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 動脈硬化の形成におけるIL-17の役割2011
- Author(s)
  臼井文武、木村博昭、岩倉洋一郎、高橋将文
- Organizer
  第32回日本炎症再生医学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 慢性甲状腺炎における免疫プロテアソームの役割。2011
- Author(s)
  木村博昭、鈴木幸一、臼井文武、Noel R. Rose、Patrizio Caturegli、高橋将文
- Organizer
  第32回日本炎症再生医学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 心血管疾患におけるインフラマソームを介した自然炎症の役割2011
- Author(s)
  高橋将文、臼井文武、木村博昭、谷口俊一郎
- Organizer
  第32回日本炎症再生医学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] カスパーゼ1ホモログ分子CARD16による新規炎症惹起機序の解析
- Author(s)
  唐澤直義、川島晃、臼井文武、木村博昭、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] LMP7欠損マウスの甲状腺異常
- Author(s)
  木村博昭、川島晃、鈴木幸一、岩間信太郎、Patrizio Caturegli、高橋将文。
- Organizer
  第8６回日本内分泌学会
- Place of Presentation
  福岡市
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] カスパーゼ1ホモログ分子CARD16による新規炎症惹起機序の解析
- Author(s)
  唐澤直義、川島晃、臼井文武、木村博昭、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] NLRP3はインフラマソーム非依存的に肝虚血再灌流障害を軽減する
- Author(s)
  高橋将文、井上賢之、白砂孔明、臼井文武、川島晃、木村博昭
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] NLRP3はインフラマソーム非依存的に肝虚血再灌流障害を軽減する
- Author(s)
  高橋将文、井上賢之、白砂孔明、臼井文武、川島晃、木村博昭
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] LMP7欠損マウスの甲状腺異常
- Author(s)
  木村博昭、川島晃、鈴木幸一、岩間信太郎、Patrizio Caturegli、高橋将文
- Organizer
  第8６回日本内分泌学会
- Place of Presentation
  福岡市
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 大動脈瘤形成におけるNLRP3インフラマソームの役割の解明
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-23591359
[Presentation] 大動脈瘤形成におけるNLRP3インフラマソームの役割の解明
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461386

1. TAKAHASHI Masafumi (40296108)

# of Collaborated Projects: 8 results

# of Collaborated Products: 81 results
2. 渡邊幸子 (80770619)

# of Collaborated Projects: 7 results

# of Collaborated Products: 30 results
3. Karasawa Tadayoshi (60631893)

# of Collaborated Projects: 5 results

# of Collaborated Products: 29 results
4. Kawanishi Fumitake (50585560)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
5. Kawashima Akira (60624913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 白砂孔明 (20552780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 鈴木幸一 (20206478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 鎌田諒 (60801420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. KASHIHARA Toshihide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. OHMORI Tsukasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 駒田敬則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 肥田重明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kimura hiroaki 木村 博昭

KIMURA HIROAKI 木村 博昭

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Analysis of differentiation capacity mechanism and functional evaluation of immunoproteasome-deficient M2 macrophagesPrincipal Investigator

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Role of the immunoproteasome in nonalcoholic steatohepatitisPrincipal Investigator

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Role of ARIH2 in the inflammasome-related cardiovascular disease

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Neutrophils in inflammatory response induced by lipid crystals

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Study of the role of the immunoproteasome in glucose- or lipid-metabolismPrincipal Investigator

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Role of adapter molecule ASC independent of inflammasome

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The study about inflammasome regulation system by protein degradation

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Molecular mechanisms underlying inflammasome-mediated cardiovascular disease

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Analysis of the role of the immunoproteasome in obesity and diabetesPrincipal Investigator

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Role of the immunoproteasome in the pathogenesis of metabolic syndromePrincipal Investigator

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[Journal Article] Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors2023

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[Journal Article] Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors2022

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[Journal Article] Crucial role of NLRP3 inflammasome in a murine model of Kawasaki disease.2020

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kimura hiroaki 木村博昭

KIMURA HIROAKI 木村博昭