Yoshida Madoka 山本円

… Alternative Names

Yamamoto Madoka 山本円

山本円ヤマモトマドカ

吉田円

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Researcher Number	70596973
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2018 – 2023: 和歌山県立医科大学, 医学部, 博士研究員 2017: 和歌山県立医科大学, 医学部, 助教 2015 – 2016: 和歌山県立医科大学, 医学部, 学内助教 2011: 和歌山県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 妊娠高血圧症候群 / 分子シャペロン / カルレティキュリン / 胎盤 / シャペロン / 小胞体 / 妊娠高血圧腎症 / 絨毛外栄養膜細胞 Except Principal Investigator 糖タンパク質 / 糖鎖修飾 … More / 卵巣がん / マンノース / トリプトファン / 糖質生物学 / 腫瘍マーカー / C-マンノシル化 / C-Man-Trp / シンシチウム化 / 胎盤形成不全 / 妊娠高血圧腎症 / カルレティキュリン / 分子シャペロン / 小胞体ストレス / 子宮癌 / アポトーシス / 分子標的療法 / 抗癌剤 / DAP kinase Less

Investigation of the pathophysiological functions of C-mannosyl tryptophan in ovarian cancer
- Principal Investigator
  
  Ihara Yoshito
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
Effects of ER stress-induced alterations in subcellular localization of ER chaperones on placentation
- Principal Investigator
  
  Ikezaki Midori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
The functional role of of calreticulin, a molecular chaperone, in dysfunctional placentationPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO MADOKA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
The mechanism of synthesis of calreticulin, a molecular chaperone, and the cellular function in trophoblastsPrincipal Investigator
- Principal Investigator
  
  Yamamoto Madoka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
DAPキナーゼを対象とする婦人科悪性腫瘍に対する新分子標的治療法の開発
- Principal Investigator
  
  田中哲二
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Extracellularly Released Calreticulin Induced by Endoplasmic Reticulum Stress Impairs Syncytialization of Cytotrophoblast Model BeWo Cells2021
- Author(s)
  Iwahashi Naoyuki、Ikezaki Midori、Nishitsuji Kazuchika、Yamamoto Madoka、Matsuzaki Ibu、Kato Naoki、Takaoka Naoyuki、Taniguchi Mana、Murata Shin-ichi、Ino Kazuhiko、Ihara Yoshito
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 6 Pages: 1305-1305
- DOI
  10.3390/cells10061305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-20K16198
[Journal Article] Lipid Droplet Accumulation Independently Predicts Poor Clinical Prognosis in High-Grade Serous Ovarian Carcinoma2021
- Author(s)
  Iwahashi Naoyuki、Ikezaki Midori、Fujimoto Masakazu、Komohara Yoshihiro、Fujiwara Yukio、Yamamoto Madoka、Mizoguchi Mika、Matsubara Kentaro、Watanabe Yudai、Matsuzaki Ibu、Murata Shin-ichi、Ihara Yoshito、Ino Kazuhiko、Nishitsuji Kazuchika
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 20 Pages: 5251-5251
- DOI
  10.3390/cancers13205251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-20K09626, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-20K16198
[Journal Article] Calreticulin regulates syncytialization through control of the synthesis and transportation of E-cadherin in BeWo cells.2019
- Author(s)
  Naoyuki Iwahashi, Midori Ikezaki, Ibu Matsuzaki, Madoka Yamamoto, Saori Toujima, Shin-ichi Murata, Yoshito Ihara, and Kazuhiko Ino
- Journal Title
  
  Endocrinology
  
  Volume: 160 Pages: 359-374
- DOI
  10.1210/en.2018-00868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16809, KAKENHI-PROJECT-16H06290
[Journal Article] Downregulation of indoleamine 2, 3-dioxygenase expression in the villous stromal endothelial cells of placentas with preeclampsia2017
- Author(s)
  Iwahashi N, Yamamoto M, Nanjo S, Toujima S, Minami S, Ino K
- Journal Title
  
  J Reprod Immunol
  
  Volume: 119 Pages: 54-60
- DOI
  10.1016/j.jri.2017.01.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462535, KAKENHI-PROJECT-15K20156
[Journal Article] Calreticulin is involved in invasion of human extravillous trophoblasts through functional regulation of integrin β12017
- Author(s)
  Madoka Yamamoto, Midori Ikezaki, Saori Toujima, Naoyuki Iwahashi, Mika Mizoguchi, Sakiko Nanjo, Sawako Minami, Yoshito Ihara, Kazuhiko Ino
- Journal Title
  
  Endocrinology
  
  Volume: 158 Issue: 11 Pages: 3874-3889
- DOI
  10.1210/en.2016-1966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-15K06981, KAKENHI-PROJECT-15K20156
[Journal Article] Levels of serum-circulating angiogenic factors within 1 week prior to delivery are closely related to conditions of pregnant women with pre-eclampsia, gestational hypertension, and/or fetal growth restriction2017
- Author(s)
  Nanjo Sakiko、Minami Sawako、Mizoguchi Mika、Yamamoto Madoka、Yahata Tamaki、Toujima Saori、Shiro Michihisa、Kobayashi Aya、Muragaki Yasuteru、Ino Kazuhiko
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 43 Issue: 12 Pages: 1805-1814
- DOI
  10.1111/jog.13452
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08430, KAKENHI-PROJECT-15K20156
[Presentation] カルネキシンはβ-hCG 発現誘導に寄与する：胎盤形成との関連2021
- Author(s)
  松川仁登美、池崎みどり、岩橋尚幸、山本円、井箟一彦、井原義人
- Organizer
  第67回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] 胎盤形成不全においてカルネキシン低下がβ-hCG 発現・分泌を抑制する2021
- Author(s)
  松川仁登美、池崎みどり、岩橋尚幸、山本円、井箟一彦、井原義人
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09476
[Presentation] カルネキシンはβ-hCG 発現誘導に寄与する：胎盤形成との関連2021
- Author(s)
  松川仁登美、池崎みどり、岩橋尚幸、山本円、井箟一彦、井原義人治、西辻和親
- Organizer
  第67回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-21K09476
[Presentation] 胎盤形成不全におけるカルネキシン発現抑制とβ-hCG発現・分泌抑制機序について2021
- Author(s)
  松川仁登美、池崎みどり、岩橋尚幸、山本円、井箟一彦、井原義人
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] 胎盤形成不全においてカルネキシン低下がβ-hCG 発現・分泌を抑制する2021
- Author(s)
  松川仁登美、池崎みどり、岩橋尚幸、山本円、井箟一彦、井原義人
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] 胎盤形成不全におけるカルネキシン発現抑制とβ-hCG発現・分泌抑制機序について2021
- Author(s)
  松川仁登美、池崎みどり、岩橋尚幸、山本円、井箟一彦、井原義人
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09476
[Presentation] 妊娠高血圧腎症における母体血液中カルレティキュリンの上昇の病態意義の検討2020
- Author(s)
  岩橋尚幸，池崎みどり，山本円，井原義人，井箟一彦
- Organizer
  第28回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] 妊娠高血圧腎症における母体血液中カルレティキュリンの上昇の病態意義の検討2020
- Author(s)
  岩橋尚幸，池崎みどり，山本円，井原義人，井箟一彦
- Organizer
  第28回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] 細胞外カルレティキュリンによる胎盤関連細胞の機能障害2019
- Author(s)
  池崎みどり、串上遥香、岩橋尚幸、山本円、西辻和親、井箟一彦、井原義人
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] 細胞性栄養膜細胞（BeWo細胞）における小胞体ストレスとカルレティキュリンの影響2019
- Author(s)
  串上遥香、岩橋尚幸、池崎みどり、山本円、井箟一彦、井原義人
- Organizer
  第66回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] 妊娠高血圧腎症における母体血液中 Calreticulin の上昇の病態意義の検討2019
- Author(s)
  岩橋尚幸、山本円、池崎みどり、松川仁登美、井原義人、井箟一彦
- Organizer
  第40回日本妊娠高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] 細胞性栄養膜細胞（BeWo細胞）における小胞体ストレスとカルレティキュリンの影響2019
- Author(s)
  串上遥香、岩橋尚幸、池崎みどり、山本円、井箟一彦、井原義人
- Organizer
  第66回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] 細胞外カルレティキュリンによる胎盤関連細胞の機能障害2019
- Author(s)
  池崎みどり、串上遥香、岩橋尚幸、山本円、西辻和親、井箟一彦、井原義人
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] 妊娠高血圧腎症における母体血液中Calreticulinの上昇の病態意義の検討2019
- Author(s)
  岩橋尚幸、山本円、池崎みどり、松川仁登美、井原義人、井箟一彦
- Organizer
  第40回日本妊娠高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09784
[Presentation] Endoplasmic reticulum chaperone calreticulin plays a key role in human placental development.2018
- Author(s)
  Naoyuki Iwahashi, Madoka Yamamoto, Yoshito Ihara, Kazuhiko Ino
- Organizer
  70th Annual Congress of the Japan Society of Obstetrics and Gynecology International Session Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] カルレティキュリンはヒト絨毛癌細胞株においてフォルスコリン誘導性のシンシチウム化に関与する2018
- Author(s)
  岩橋尚幸、池崎みどり、山本円、井箟一彦、井原義人
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] カルレティキュリンはヒト絨毛癌細胞株(BeWo)においてE-カドヘリンの細胞表面への輸送に関与する2018
- Author(s)
  岩橋尚幸、池崎みどり、山本円、井箟一彦、井原義人
- Organizer
  第65回近畿支部例会
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] Endoplasmic reticulum molecular chaperone calreticulin plays a key role in human placentation.2018
- Author(s)
  Naoyuki Iwahashi, Midori Ikezaki, Madoka Yamamoto, Yoshito Ihara, Kazuhiko Ino
- Organizer
  International Federation of Placenta Associations
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16809
[Presentation] カルレティキュリンはインテグリンβ1への関与を介しヒト絨毛外栄養膜細胞浸潤を制御する2017
- Author(s)
  山本円，岩橋　尚幸，池﨑　みどり，井箟　一彦，井原　義人
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15K20156
[Presentation] カルレティキュリンはインテグリンへの関与を介し絨毛外栄養膜細胞浸潤を制御する2016
- Author(s)
  山本円，池﨑みどり，東嶋左緒里，岩橋尚幸，南條佐輝子，溝口美佳，城道久，太田菜美，馬淵泰士，八木重孝，南佐和子，井原義人，井箟一彦
- Organizer
  第24回日本胎盤学会
- Place of Presentation
  和歌山
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K20156
[Presentation] 小胞体分子シャペロンであるカルレティキュリンは絨毛外栄養膜細胞浸潤に関与する2016
- Author(s)
  山本円，岩橋尚幸，南條佐輝子，溝口美佳，小林彩，谷崎優子，城道久，太田菜美，馬淵泰士，八木重孝，南佐和子，井箟一彦
- Organizer
  日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K20156
[Presentation] 絨毛外栄養膜細胞浸潤における小胞体分子シャペロン・カルレティキュリンの役割2016
- Author(s)
  山本円，池﨑みどり，東嶋左緒里，岩橋尚幸，南條佐輝子，溝口美佳，城道久，太田菜美，馬淵泰士，八木重孝，南佐和子，井原義人，井箟一彦
- Organizer
  第37回日本妊娠高血圧学会
- Place of Presentation
  埼玉
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K20156

1. Ikezaki Midori (40549747)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. Ihara Yoshito (70263241)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 岩橋尚幸 (50750907)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
4. 田中哲二 (80275255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宇都宮洋才 (60264876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 佐々木徳之 (40596970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小林彩 (50596971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 東嶋左緒里 (70597814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 井内陽子 (20316087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 南方志帆 (90508574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 眞鍋史乃 (60300901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 伊藤幸成

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 井箟一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 村垣泰光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshida Madoka 山本 円

Yamamoto Madoka 山本 円

山本 円 ヤマモト マドカ

吉田 円

Research Projects

Research Products

Co-Researchers

Investigation of the pathophysiological functions of C-mannosyl tryptophan in ovarian cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of ER stress-induced alterations in subcellular localization of ER chaperones on placentation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The functional role of of calreticulin, a molecular chaperone, in dysfunctional placentationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of synthesis of calreticulin, a molecular chaperone, and the cellular function in trophoblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DAPキナーゼを対象とする婦人科悪性腫瘍に対する新分子標的治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Extracellularly Released Calreticulin Induced by Endoplasmic Reticulum Stress Impairs Syncytialization of Cytotrophoblast Model BeWo Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipid Droplet Accumulation Independently Predicts Poor Clinical Prognosis in High-Grade Serous Ovarian Carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Calreticulin regulates syncytialization through control of the synthesis and transportation of E-cadherin in BeWo cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Downregulation of indoleamine 2, 3-dioxygenase expression in the villous stromal endothelial cells of placentas with preeclampsia2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Calreticulin is involved in invasion of human extravillous trophoblasts through functional regulation of integrin β12017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Levels of serum-circulating angiogenic factors within 1 week prior to delivery are closely related to conditions of pregnant women with pre-eclampsia, gestational hypertension, and/or fetal growth restriction2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] カルネキシンはβ-hCG 発現誘導に寄与する：胎盤形成との関連2021

Author(s)

Organizer

Data Source

[Presentation] 胎盤形成不全においてカルネキシン低下がβ-hCG 発現・分泌を抑制する2021

Author(s)

Organizer

Data Source

[Presentation] カルネキシンはβ-hCG 発現誘導に寄与する：胎盤形成との関連2021

Author(s)

Organizer

Data Source

[Presentation] 胎盤形成不全におけるカルネキシン発現抑制とβ-hCG発現・分泌抑制機序について2021

Yoshida Madoka 山本円

Yamamoto Madoka 山本円

山本円ヤマモトマドカ

吉田円