Hirai Kazuyuki 平井和之

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HIRAI Kazuyuki 平井和之

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Researcher Number	70597335
Other IDs	https://orcid.org/0000-0003-1640-3667
Affiliation (Current)	2025: 杏林大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 杏林大学, 医学部, 准教授 2012 – 2023: 杏林大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 39050:Insect science-related / Genetics/Chromosome dynamics / Genetics/Genome dynamics Except Principal Investigator Basic Section 45010:Genetics-related / Neurophysiology / General neuroscience / Basic Section 44020:Developmental biology-related
Keywords	Principal Investigator 受精 / 前核 / 紡錘体 / 減数分裂 / 染色体 / 単為生殖 / ゲノム / ショウジョウバエ / 単為発生 / 中心体 … More / 遺伝学 / 母性因子 / 核膜孔複合体 / 有糸分裂 / 受精卵 / 二倍体化 / 未受精卵 / 接合子 / 細胞周期 / 二倍体 … More Except Principal Investigator ショウジョウバエ / 生殖的隔離 / 遺伝的不和合 / 種間雑種 / 核膜孔複合体 / 遺伝子 / 発生・分化 / 脳・神経 / 脳 / 脳神経回路 / 神経発生 / 神経回路 / 発生遺伝学 / 神経科学 / 細胞系譜 / クローン解析 / 神経幹細胞 / 脳神経細胞 / 進化 / 幹細胞 / 脳神経 / キイロショウジョウバエ / 増殖 / 脱分化 / 中枢神経系 / 可塑性 / グリア細胞 Less

受精期の二倍体核形成における核膜孔複合体の役割Principal Investigator
- Principal Investigator
  
  平井和之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 39050:Insect science-related
- Research Institution
  Kyorin University
核膜孔複合体のコンポーネント間相互作用とその不和合による生殖的隔離
- Principal Investigator
  
  澤村京一
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  University of Tsukuba
ショウジョウバエ受精卵における紡錘体融合による二倍体核形成機構Principal Investigator
- Principal Investigator
  
  平井和之
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 39050:Insect science-related
- Research Institution
  Kyorin University
Molecular mechanisms underlying the proliferation of differentiated glial cells in Drosophila melanogaster
- Principal Investigator
  
  Kato Kentaro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kyorin University
Diversity of genetic programs for brain development and structure in Drosophila species
- Principal Investigator
  
  Awasaki Takeshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Kyorin University
Genetic basis of the initiation of sexual and parthenogenetic development in DrosophilaPrincipal Investigator
- Principal Investigator
  
  HIRAI Kazuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Kyorin University
Initiation of nuclear divisions and restoration of diploidy in parthenogenetic embryos of Drosophila ananassaePrincipal Investigator
- Principal Investigator
  
  HIRAI Kazuyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Kyorin University

All 2023 2022 2021 2020 2018 2017 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Mitotic progression and dual spindle formation caused by spindle association of de novo-formed microtubule-organizing centers in parthenogenetic embryos of Drosophila ananassae2023
- Author(s)
  Hirai K, Inoue YH, Matsuda M
- Journal Title
  
  Genetics
  
  Volume: 223 Issue: 2 Pages: 1-17
- DOI
  10.1093/genetics/iyac178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06078, KAKENHI-PROJECT-21K06277
[Journal Article] Genetic Analyses of Elys mutations in Drosophila Show Maternal-effect Lethality and Interactions with Nucleoporin Genes2018
- Author(s)
  Kazuyuki Hirai, Zhuo Wang, Kohei Miura, Takaaki Hayashi, Takeshi Awasaki, Moe Wada, Yoko Keira, Hiroyuki O. Ishikawa, Kyoichi Sawamura
- Journal Title
  
  G3
  
  Volume: 印刷中
- NAID
  120007133936
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] The nuclear envelope functions in forming the first mitotic spindle essential for diploidization of haploid parental chromosome complements in Drosophila2023
- Author(s)
  Kazuyuki Hirai and Kyoichi Sawamura
- Organizer
  Gordon Research Conference on Fertilization and Activation of Development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06078
[Presentation] The nuclear envelope functions in forming the first mitotic spindle essential for diploidization of haploid parental chromosome complements in Drosophila2023
- Author(s)
  Kazuyuki Hirai, Kyoichi Sawamura
- Organizer
  Gordon Research Conference, Fertilization and Activation of Development, The Basics of Gamete Biology and Early Development and Their Clinical Implications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06755
[Presentation] Diploidization of haploid chromosome complements is driven by the first mitotic spindle organized by centrosomes in Drosophila2023
- Author(s)
  Hirai K, Sawamura K
- Organizer
  The Cold Spring Harbor Asia meeting on Cilia and Centrosomes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06078
[Presentation] Diploidization of haploid chromosome complements is driven by the first mitotic spindle organized by centromeres in Drosophila2022
- Author(s)
  Kazuyuki Hirai, Kyoichi Sawamura
- Organizer
  Cold Spring Harbor Asia, Cilia and Centromeres
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06755
[Presentation] ELYS, a factor recruiting nuclear pore complex, is involved in reproductive isolation2021
- Author(s)
  Kyoichi Sawamura, Kazuyuki Hirai, Hiroki Sakamoto, Yoko Keira, Hiroyuki O. Ishikawa, Kanta Yamazoe, Mika Ozaki, Yoshihiro H. Inoue
- Organizer
  Japan Drosophila Research Conference
- Data Source
  KAKENHI-PROJECT-20K06755
[Presentation] ショウジョウバエの核膜孔複合体リクルート因子ELYS―近縁種の比較2021
- Author(s)
  澤村京一・平井和之・坂本大季・計良陽子・石川裕之・山添幹太・井上喜博
- Organizer
  日本遺伝学会
- Data Source
  KAKENHI-PROJECT-20K06755
[Presentation] ELYS, a factor recruiting nuclear pore complex, is involved in reproductive isolation2021
- Author(s)
  Kyoichi Sawamura, Kazuyuki Hirai, Hiroki Sakamoto, Yoko Keira, Hiroyuki O. Ishikawa, Kanta Yamazoe, Mika Ozaki, Yoshihiro H. Inoue
- Organizer
  14th Japan Drosophila Research Conference
- Data Source
  KAKENHI-PROJECT-19K06078
[Presentation] ショウジョウバエの核膜孔複合体リクルート因子ELYS－近縁種間の比較2021
- Author(s)
  澤村京一、平井和之、坂本大季、計良陽子、石川裕之、山添幹太、井上喜博
- Organizer
  日本遺伝学会第93回大会
- Data Source
  KAKENHI-PROJECT-19K06078
[Presentation] ショウジョウバエの受精期における核膜孔複合体タンパク質Elysの役割2020
- Author(s)
  平井和之
- Organizer
  日本細胞生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06755
[Presentation] ショウジョウバエの近縁種間における核膜孔複合体リクルート因子ELYSの機能比較2020
- Author(s)
  坂本大季・平井和之・計良陽子・石川裕之・山添幹太・井上喜博・澤村京一
- Organizer
  日本遺伝学会
- Data Source
  KAKENHI-PROJECT-20K06755
[Presentation] ショウジョウバエの受精期における核膜孔複合体タンパク質Elysの役割2020
- Author(s)
  平井和之
- Organizer
  第72回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06078
[Presentation] ショウジョウバエの近縁種間における核膜孔複合体リクルート因子ELYSの機能比較2020
- Author(s)
  坂本大季、平井和之、計良陽子、石川裕之、山添幹太、井上喜博、澤村京一
- Organizer
  第92回日本遺伝学会大会
- Data Source
  KAKENHI-PROJECT-19K06078
[Presentation] 核膜孔複合体タンパク質ELYSの変異によるショウジョウバエの発生異常2017
- Author(s)
  澤村京一，平井和之，Wang Zhuo，粟崎健，和田萌，計良陽子，石川裕之
- Organizer
  第89回日本遺伝学会
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] The initiation and progression of the earliest cycles in parthenogenetic Drosophila ananassae.2017
- Author(s)
  Hirai K, Suzuki H, Minakuchi Y, Toyoda A, Matsuda M
- Organizer
  THE 4TH ASIA-PACIFIC DROSOPHILA RESEARCH CONFERENCE
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] アナナスショウジョウバエの単為発生における核分裂開始機構2017
- Author(s)
  平井和之、水口洋平、豊田敦、松田宗男
- Organizer
  2106年度国立遺伝学研究所研究会　ショウジョウバエの生殖システムと生殖戦略
- Place of Presentation
  静岡県三島市
- Year and Date
  2017-02-07
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] The progression of the first mitosis and diploidization in parthenogenetic embryos of Drosophila ananassae2016
- Author(s)
  Hirai, Kazuyuki, Suzuki, Haruka, Minakuchi, Yohei, Toyoda, Atsushi, Matsuda, Muneo.
- Organizer
  22nd International Congress of Zoology/第87回日本動物学会大会　合同大会
- Place of Presentation
  沖縄県宜野湾市
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] The progression of the first mitosis and diploidization in parthenogenetic embryos of Drosophila ananassae2016
- Author(s)
  Kazuyuki Hirai, Haruka Suzuki, Yohei Minakuchi, Atsushi Toyoda, Muneo Matsuda.
- Organizer
  第12回日本ショウジョウバエ研究会
- Place of Presentation
  東京
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] アナナスショウジョウバエの単為発生における核分裂開始機構2015
- Author(s)
  平井　和之、鈴木　遥、水口　洋平、豊田　敦、松田　宗男
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] De novo formation of centrosome-like structures and their roles in the progression of the first mitosis and diploid nucleus formation in parthenogenetic embryos of Drosophila ananassae2015
- Author(s)
  Kazuyuki Hirai, Yohei Minakuchi, Atsushi Toyoda, Muneo Matsuda
- Organizer
  EMBO Workshop Cell cycle
- Place of Presentation
  Danubius Health Spa Resort Margitsziget（ブダペスト、ハンガリー）
- Year and Date
  2015-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] アナナスショウジョウバエ単為発生胚における核分裂開始と二倍体核形成機構2015
- Author(s)
  平井　和之、鈴木　遥、水口　洋平、豊田　敦、松田　宗男
- Organizer
  日本動物学会第86回新潟大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K14576
[Presentation] アナナスショウジョウバエにおける単為発生開始機構の解析2013
- Author(s)
  平井和之、松田宗男
- Organizer
  国立遺伝学研究所共同研究会、ショウジョウバエ多様性研究会
- Place of Presentation
  三島市
- Invited
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] De novo synthesis of centrosomes and diploidization in parthenogenetic embryos of Drosophila ananassae2013
- Author(s)
  Kazuyuki Hirai, Akihiko Kudo, and Muneo Matsuda
- Organizer
  EMBO workshop Drosophila cell division cycle
- Place of Presentation
  トットネス、英国
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] De novo centrosome synthesis and diploidization in parthenogenetic embryos of Drosophila ananassae-complex species2013
- Author(s)
  Kazuyuki Hirai, Muneo Matsuda
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] de novo centrosome synthesis in parthenogenetic embryos of Drosophila ananassae-complex species2013
- Author(s)
  平井和之、宮東昭彦、松田宗男
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] アナナスショウジョウバエ単為発生系統における2倍体化機構の解析2012
- Author(s)
  平井和之、宮東昭彦、松田宗男
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] Cellular basis of diploidization in Drosophila ananassae parthenogenesis2012
- Author(s)
  Kazuyuki Hirai, Akihiko Kudo, and Muneo Matsuda
- Organizer
  Germ Cells
- Place of Presentation
  Cold Spring Harbor、米国
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] De novo centrosome synthesis and diploidization in parthenogenetic embryos of Drosophila ananassae-complex species
- Author(s)
  Kazuyuki Hirai, Akihiko Kudo, Yukio Shima, Yohei Minakuchi, Atsushi Toyoda, Muneo Matsuda
- Organizer
  The 11th Japanese Drosophila Research Conference
- Place of Presentation
  石川県、金沢歌劇座
- Year and Date
  2014-06-04 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] De novo synthesis of centrosome-like structures and diploidization in partheogenetic embryos of Drosophila ananassae
- Author(s)
  Kazuyuki Hirai, Yukio Shima, Yohei Minakuchi, Atsushi Toyoda, Muneo Matsuda
- Organizer
  Cold Spring Harbor Laboratory meeting on Germ Cells
- Place of Presentation
  Cold Spring Harbor Laboratory、米国ニューヨーク州
- Year and Date
  2014-10-07 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-24770006
[Presentation] De novo centrosome synthesis and diploidization in partheogenetic embryos of Drosophila ananassae
- Author(s)
  平井和之、島幸夫、水口洋平、豊田敦、松田宗男
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  滋賀県、長浜バイオ大学
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-24770006

1. Kato Kentaro (30733068)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Awasaki Takeshi (60359669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 佐藤玄 (70301299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 澤村京一 (90247205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 井上喜博 (90201938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石川裕之 (00398819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 井上寿博

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Hirai Kazuyuki 平井 和之

HIRAI Kazuyuki 平井 和之

Research Projects

Research Products

Co-Researchers

受精期の二倍体核形成における核膜孔複合体の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

核膜孔複合体のコンポーネント間相互作用とその不和合による生殖的隔離

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ショウジョウバエ受精卵における紡錘体融合による二倍体核形成機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms underlying the proliferation of differentiated glial cells in Drosophila melanogaster

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diversity of genetic programs for brain development and structure in Drosophila species

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic basis of the initiation of sexual and parthenogenetic development in DrosophilaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Initiation of nuclear divisions and restoration of diploidy in parthenogenetic embryos of Drosophila ananassaePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mitotic progression and dual spindle formation caused by spindle association of de novo-formed microtubule-organizing centers in parthenogenetic embryos of Drosophila ananassae2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic Analyses of Elys mutations in Drosophila Show Maternal-effect Lethality and Interactions with Nucleoporin Genes2018

Author(s)

Journal Title

NAID

Data Source

[Presentation] The nuclear envelope functions in forming the first mitotic spindle essential for diploidization of haploid parental chromosome complements in Drosophila2023

Author(s)

Organizer

Data Source

[Presentation] The nuclear envelope functions in forming the first mitotic spindle essential for diploidization of haploid parental chromosome complements in Drosophila2023

Author(s)

Organizer

Data Source

[Presentation] Diploidization of haploid chromosome complements is driven by the first mitotic spindle organized by centrosomes in Drosophila2023

Author(s)

Organizer

Data Source

[Presentation] Diploidization of haploid chromosome complements is driven by the first mitotic spindle organized by centromeres in Drosophila2022

Author(s)

Organizer

Data Source

[Presentation] ELYS, a factor recruiting nuclear pore complex, is involved in reproductive isolation2021

Author(s)

Organizer

Data Source

[Presentation] ショウジョウバエの核膜孔複合体リクルート因子ELYS―近縁種の比較2021

Author(s)

Organizer

Hirai Kazuyuki 平井和之

HIRAI Kazuyuki 平井和之