Nakajima Yoko 中島葉子

… Alternative Names

中島葉子ナカジマヨウコ

NAKAJIMA Yoko 中島葉子

Less

Researcher Number	70598309
Other IDs	https://orcid.org/0000-0002-6944-4131
Affiliation (Current)	2024: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022: 藤田医科大学, 医学部, 講師 2017: 藤田保健衛生大学, 医学部, 講師 2014 – 2017: 藤田保健衛生大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Medical pharmacy / Pediatrics Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator UPLC-MS/MS / 5-フルオロウラシル / 尿中ピリミジン代謝物分析 / ピリミジン代謝異常症 / 薬物動態代謝スクリーニング / 遺伝子検査 / 薬物代謝スクリーニング / 薬物代謝スクリーニング検査 / 5-FU関連抗癌剤 / DPD酵素活性測定 … More / 薬物代謝スクスクリーニング / ハイリスクスクリーニンング / 5FU薬物代謝 / 5FU関連抗癌剤代謝 / 先天性ピリミジン代謝異常症診断システム / 遺伝子診断 / ハイリスクスクリーニング … More Except Principal Investigator 有機酸代謝異常症 / N-アセチルグルタミン酸 / 有機酸代謝異常 / アセチルグルタミン酸合成酵素 / アセチルグルタミン酸 / プロピオン酸血症 / メチルマロン酸血症 / 高アンモニア血症 Less

有機酸代謝異常症における高アンモニア血症発生機構に関する研究
- Principal Investigator
  
  前田康博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Fujita Health University
Diagnosis of pyrimidine degradation disorder in patients with severe 5-FU side effectPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Yoko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fujita Health University
Diagnostic method for inborn errors of pyrimidine metabolismPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Yoko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Fujita Health University

All 2022 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] A Japanese case of β-ureidopropionase deficiency with dysmorphic features2017
- Author(s)
  Akiyama, T., Shibata, T., Yoshinaga, H., Kuhara, T., Nakajima, Y., Kato, T., Maeda, Y., Ohse, M., Oka, M., Kageyama, M., Kobayashi, K.
- Journal Title
  
  Brain and Development
  
  Volume: 39 Issue: 1 Pages: 58-61
- DOI
  10.1016/j.braindev.2016.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-15K19042, KAKENHI-PROJECT-16K18961, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-17K11259
[Journal Article] Dihydropyrimidinase deficiency in four East Asian patients due to novel and rare DPYS mutations affecting protein structural integrity and catalytic activity.2017
- Author(s)
  Nakajima Y, Meijer J, Dobritzsch D, Ito T, Zhang C, Wang X, Watanabe Y, Tashiro K, Meinsma R, Roelofsen J, Zoetekouw L, van Kuilenburg ABP
- Journal Title
  
  Molecular genetics and metabolism
  
  Volume: 122 Pages: 216-222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18961
[Journal Article] Altered Pre-mRNA Splicing Caused by a Novel Intronic Mutation c.1443+5G>A in the Dihydropyrimidinase (DPYS) Gene.2016
- Author(s)
  Nakajima Y, Meijer J, Zhang C, Wang X, Kondo T, Ito T, Dobritzsch D, Van Kuilenburg AB.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 17(1) Issue: 1 Pages: 86-8
- DOI
  10.3390/ijms17010086
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860818
[Journal Article] UPLC-MS/MS によるピリミジン代謝異常症スクリーニング法につい2015
- Author(s)
  前田康博，中島葉子，伊藤哲哉
- Journal Title
  
  Japanese Society for Biomedical Mass Spectrometry
  
  Volume: Vol. 40 No.1 Pages: 4-10
- Data Source
  KAKENHI-PROJECT-26860818
[Journal Article] Clinical, biochemical and molecular analysis of 13 Japanese patients with β-ureidopropionase deficiency demonstrates high prevalence of the c.977G > A (p.R326Q) mutation2014
- Author(s)
  Nakajima Y, Meijer J, Dobritzsch D, Ito T, Meinsma R, Abeling NGGM, Roelofsen J, Zoetekouw L, Watanabe Y, Lee T, Mitsubuchi H, Yoneyama A, Ohta K, Kuhara T, Eto K, Saito K, van Kuilenburg ABP
- Journal Title
  
  J Inherit Metab Dis
  
  Volume: 37 Issue: 5 Pages: 801-812
- DOI
  10.1007/s10545-014-9682-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591591, KAKENHI-PROJECT-26860818
[Presentation] メチルマロン酸血症における新生児マススクリーニング時のC3値および酵素活性と症例との関連2022
- Author(s)
  前田康博、中島葉子、横井克幸、伊藤哲哉
- Organizer
  第63回日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-22K08683
[Presentation] β-ウレイドプロピオナーゼ欠損症30例における分子遺伝学解析：東南アジアにおけるコモン変異R326Qの発見2015
- Author(s)
  中島葉子, Judith Meijer, 張春花, 渡邊順子, 久原とみ子,伊藤哲哉, André B.P. van Kuilenburg
- Organizer
  第60回日本人類遺伝学会
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26860818
[Presentation] UPLC-MS/MSによるピリミジン塩基代謝物の定量によるピリミジン代謝異常症スクリーニング2015
- Author(s)
  前田康博、後藤加奈、中島葉子、前田葉子、堀田祐志、片岡智哉、川出義浩、伊藤哲哉、木村和哲
- Organizer
  第40回日本医用マススペクトル学会
- Place of Presentation
  浜松　アクトシティ浜松　コングレスセンター
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26860818
[Presentation] High prevalence of the mutation R326Q in 30 children with β-ureidoproionase deficiency in East Asia2015
- Author(s)
  Yoko Nakajima, Judith Meijer, Chunhua Zhang, Yoriko Watanabe, Tomoko Lee, Hiroshi Mitsubuchi, Kaoru Eto, Tomiko Kuhara, Tetsuya Ito, Andre van Kuilenburg
- Organizer
  第57回日本小児神経学会
- Place of Presentation
  大阪　帝国ホテル
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26860818
[Presentation] Clinical, biochemical and molecular analysis of 30 children with β-ureidoproionase deficiency demonstrates high prevalence of the c.977G>A(p.R326Q) mutation2015
- Author(s)
  Yoko Nakajima, Judith Meijer, Chunhua Zhang, Yoriko Watanabe, Tomoko Lee, Hiroshi Mitsubuchi, Kaoru Eto, Tomiko Kuhara, Tetsuya Ito, Andre van Kuilenburg
- Organizer
  16th international Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  New York,　Columbia University
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860818
[Presentation] Clinical, biochemical and molecular analysis of 30 children with β-ureidopropionase deficiency demonstrates high prevalence of the c.977G>A (p.R326Q) mutation
- Author(s)
  Yoko Nakajima, Judith Meijer, Doreen Dobritzsch, Chunhua Zhang, Tetsuya Ito, Yoriko Watanabe, Tomiko Kuhara, and André B.P. van Kuilenburg
- Organizer
  The 4th　Asiaan Congress for Inherited Metabolic diseases
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2015-03-19 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-26860818
[Presentation] Clinical, biochemical and molecular analysis of 13 Japanese patients with β-ureidopropionase deficiency demonstrates high prevalence of the c.977G>A (p.R326Q) mutation
- Author(s)
  Yoko Nakajima, Judith Meijer, Doreen Dobritzsch, Tetsuya Ito, Rutger Meinsma, Lida Zoetekouw, Yoriko Watanabe, Kyoko Tashiro, Tomoko Lee, Yasuhiro Takeshima, Hiroshi Mitsubuchi, Akira Yoneyama, Kazuhide Ohta, Kaoru Eto, Kayoko Saito, Tomiko Kuhara, A.B.P. van Kuilenburg
- Organizer
  SSIEM Annual Symposium 2014
- Place of Presentation
  Innsbruck, Tyrol, Austria.
- Year and Date
  2014-09-02 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26860818
[Presentation] β-ウレイドプロピオナーゼ欠損症13例の生化学的・分子生物学的解析とUPB1遺伝子p.R326Q変異頻度の検討
- Author(s)
  Yoko Nakajima, Judith Meijer, Doreen Dobritzsch, Yoriko Watanabe, Tomiko Kuhara, Hiroshi Mitsubuchi, Tomoko Lee, Kaoru Eto, Tetsuya Ito, André B.P. van Kuilenburg
- Organizer
  第56回日本先天代謝異常学会総会 / 第12回アジア先天代謝異常症シンポジウム
- Place of Presentation
  宮城県仙台市江陽グランドホテル
- Year and Date
  2014-11-13 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-26860818

1. 前田康博 (60275146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 伊藤哲哉 (80336677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 太田和秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakajima Yoko 中島 葉子

中島 葉子 ナカジマ ヨウコ

NAKAJIMA Yoko 中島 葉子

Research Projects

Research Products

Co-Researchers

有機酸代謝異常症における高アンモニア血症発生機構に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diagnosis of pyrimidine degradation disorder in patients with severe 5-FU side effectPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Diagnostic method for inborn errors of pyrimidine metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A Japanese case of β-ureidopropionase deficiency with dysmorphic features2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dihydropyrimidinase deficiency in four East Asian patients due to novel and rare DPYS mutations affecting protein structural integrity and catalytic activity.2017

Author(s)

Journal Title

Data Source

[Journal Article] Altered Pre-mRNA Splicing Caused by a Novel Intronic Mutation c.1443+5G>A in the Dihydropyrimidinase (DPYS) Gene.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] UPLC-MS/MS によるピリミジン代謝異常症スクリーニング法につい2015

Author(s)

Journal Title

Data Source

[Journal Article] Clinical, biochemical and molecular analysis of 13 Japanese patients with β-ureidopropionase deficiency demonstrates high prevalence of the c.977G > A (p.R326Q) mutation2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] メチルマロン酸血症における新生児マススクリーニング時のC3値および酵素活性と症例との関連2022

Author(s)

Organizer

Data Source

[Presentation] β-ウレイドプロピオナーゼ欠損症30例における分子遺伝学解析： 東南アジアにおけるコモン変異R326Qの発見2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] UPLC-MS/MSによるピリミジン塩基代謝物の定量によるピリミジン代謝異常症スクリーニング2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] High prevalence of the mutation R326Q in 30 children with β-ureidoproionase deficiency in East Asia2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Clinical, biochemical and molecular analysis of 30 children with β-ureidoproionase deficiency demonstrates high prevalence of the c.977G>A(p.R326Q) mutation2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Clinical, biochemical and molecular analysis of 30 children with β-ureidopropionase deficiency demonstrates high prevalence of the c.977G>A (p.R326Q) mutation

Author(s)

Organizer

Place of Presentation

Year and Date

Nakajima Yoko 中島葉子

中島葉子ナカジマヨウコ

NAKAJIMA Yoko 中島葉子

[Presentation] β-ウレイドプロピオナーゼ欠損症30例における分子遺伝学解析：東南アジアにおけるコモン変異R326Qの発見2015