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Tonomura Hitoshi  外村 仁

ORCIDConnect your ORCID iD *help
Researcher Number 70604304
Other IDs
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 講師
2015 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related
Except Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Rehabilitation science/Welfare engineering
Keywords
Principal Investigator
椎間板 / メカニカルストレス / メカノバイオロジー / 運動 / PRP / 椎体形成術 / HIF-1α / サルコペニア / 骨粗鬆症 / HGF … More
Except Principal Investigator
… More 骨粗鬆症性椎体骨折 / 医療・福祉 / 椎間板細胞 / 椎体形成術 / β-TCP / 骨粗鬆症 / 多血小板血漿 / 椎間板変性抑制 / 肝細胞増殖因子 / 椎間板 / HIF-1α / 低酸素 / HGF / オートファジー Less
  • Research Projects

    (6 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (9 People)
  •  The development of bone regenerative method for the osteoporotic vertebral fracture inducing osteoblasts and macrophages

    • Principal Investigator
      長江 将輝
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Mechanobiological responses of intervertebral disc to various intensity of stress loadingPrincipal Investigator

    • Principal Investigator
      外村 仁
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Bone-to-muscle network mediated by HGF/c-Met signaling in osteoporosisPrincipal Investigator

    • Principal Investigator
      Tonomura Hitoshi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Analysis of disc homeostasis maintenance mechanism by hypoxia response via HGF / c-Met signal

    • Principal Investigator
      Mikami Yasuo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of vertebroplasty using autologous platelet rich plasma for osteoporotic vertebral body fracture

    • Principal Investigator
      Nagae Masateru
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Establishment of elucidation and control method of autophagy mechanism of disc cells using original pressure loading device

    • Principal Investigator
      Ikeda Takumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2021 2020

All Journal Article Presentation

  • [Journal Article] The Potential Role of Hepatocyte Growth Factor in Degenerative Disorders of the Synovial Joint and Spine2020

    • Author(s)
      Tonomura Hitoshi、Nagae Masateru、Takatori Ryota、Ishibashi Hidenobu、Itsuji Tomonori、Takahashi Kenji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 22 Pages: 8717-8717

    • DOI

      10.3390/ijms21228717

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09116
  • [Journal Article] Hepatocyte growth factor regulates HIF-1α-induced nucleus pulposus cell proliferation through MAPK-, PI3K/Akt-, and STAT3-mediated signaling2020

    • Author(s)
      Itsuji T、Tonomura H、Ishibashi H、Mikami Y、Nagae M、Takatori R、Tanida T、Matsuda KI、Tanaka M、Kubo T
    • Journal Title

      Journal of Orthopaedic Research

      Volume: - Issue: 6 Pages: 1184-1191

    • DOI

      10.1002/jor.24679

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03553, KAKENHI-PROJECT-18K09116, KAKENHI-PROJECT-20K08186, KAKENHI-PROJECT-17K10188
  • [Presentation] 肝細胞増殖因子が髄核細胞のHIF-1α発現と細胞増殖に与える影響2021

    • Author(s)
      井辻智典,外村 仁,長江将輝,高取良太,清水佑一,石橋秀信,谷田任司,松田賢一,田中雅樹,高橋謙治
    • Organizer
      第36回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-18K09116
  • 1.  Nagae Masateru (60604303)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 2.  Ikeda Takumi (40453120)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  Mikami Yasuo (80360030)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  沢田 光思郎 (40460555)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  高取 良太 (10351355)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  ITSUJI TOMONORI
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  石橋 秀信 (80981505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SAKATA MUNEHIRO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  田中 雅樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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