Yagi Hiroshi 八木裕史

… Alternative Names

YAGI Hiroshi 八木裕史

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Researcher Number	70623552
Other IDs
Affiliation (Current)	2025: 九州大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2025: 九州大学, 大学病院, 講師 2021 – 2023: 九州大学, 医学研究院, 助教 2017 – 2019: 九州大学, 医学研究院, 助教 2012 – 2016: 九州大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator シグナル伝達 / 卵巣癌 / GPCR / 転移 / 細胞増殖 / Rho / 癌 / 子宮頸癌 / 三量体Gタンパク / 低分子量Gタンパク … More / AP-1 / 子宮体癌 / 婦人科腫瘍 / EMT / Gタンパク / 上皮間葉転換 / 浸潤 … More Except Principal Investigator 診断マイクロアレイ / マイクロRNA / microRNA array / microRNA / miR-135a-3p / miRNA / BK-UM / HB-EGF / バイオマーカー / 卵巣癌 Less

細胞接着型GPCRの機能解析に基づく卵巣癌治療標的の探索Principal Investigator
- Principal Investigator
  
  八木裕史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyushu University
The role of heterotrimeric G protein in the progression of gynecological cancerPrincipal Investigator
- Principal Investigator
  
  Yagi Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyushu University
The role of Ga13 in the progression of gynecologic cancerPrincipal Investigator
- Principal Investigator
  
  Yagi Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Searching gene to manufacture the companion diagnostic agent targeting the HB-EGF.
- Principal Investigator
  
  Miyamoto Shingo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Fukuoka University
The role of GPCR signaling in gynecologic cancer progressionPrincipal Investigator
- Principal Investigator
  
  Hiroshi Yagi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
The role of GPCR signaling in the progression of gynecological cancerPrincipal Investigator
- Principal Investigator
  
  YAGI Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University

All 2023 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer2022
- Author(s)
  Yagi H, Onoyama I, Asanoma K, Kawakami M, Maenohara S, Kodama K, Matsumura Y, Hamada N, Hori E, Hachisuga K, Yasunaga M, Ohgami T, Okugawa K, Yahata H, Kato K.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 30 Issue: 2 Pages: 313-323
- DOI
  10.1038/s41417-022-00547-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09496, KAKENHI-PROJECT-21K09519, KAKENHI-PROJECT-22K19604, KAKENHI-PROJECT-21K09520
[Journal Article] Gα13-mediated LATS1 down-regulation contributes to epithelial-mesenchymal transition in ovarian cancer2019
- Author(s)
  Yagi Hiroshi、Onoyama Ichiro、Asanoma Kazuo、Hori Emiko、Yasunaga Masafumi、Kodama Keisuke、Kijima Masako、Ohgami Tatsuhiro、Kaneki Eisuke、Okugawa Kaoru、Yahata Hideaki、Kato Kiyoko
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 12 Pages: 13683-13694
- DOI
  10.1096/fj.201901278r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03800, KAKENHI-PROJECT-17K11280, KAKENHI-PROJECT-17K11282
[Journal Article] GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer2016
- Author(s)
  Yagi H, Asanoma K, Ohgami T, Ichinoe A, Sonoda K, Kato K.
- Journal Title
  
  Oncogene
  
  Volume: 10 Issue: 34 Pages: 1-10
- DOI
  10.1038/onc.2015.505
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861332, KAKENHI-PROJECT-26462529
[Journal Article] Uterine myxoid leiomyosarcoma with tumor embolism extending into the right atrium2015
- Author(s)
  Hiromi Imai, Hiroshi Yagi, Kaoru Okugawa, Hironori Kenjo, Tatsuhiro Ohgami, Yoshiaki Kawano, Eisuke Kaneki, Akimasa Ichinoe, Kazuo Asanoma, Hideaki Yahata, Kenzo Sonoda, Hiroaki Kobayashi, Tsunehisa Kaku, Kiyoko Kato
- Journal Title
  
  Case Reports in Obstetrics and Gynecology
  
  Volume: 2015 Pages: 316262-316262
- DOI
  10.1155/2015/316262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592519, KAKENHI-PROJECT-24592520, KAKENHI-PROJECT-26462529, KAKENHI-PROJECT-26861332
[Journal Article] SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers.2015
- Author(s)
  Okamoto K, Tsunematsu R, Tahira T, Sonoda K, Asanoma K, Yagi H, Yoneda T, Hayashi K, Wake N, Kato K
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 16 Issue: 1 Pages: 67-67
- DOI
  10.1186/s12881-015-0216-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462529, KAKENHI-PROJECT-15K15608, KAKENHI-PUBLICLY-15H01517, KAKENHI-PROJECT-26861332
[Journal Article] Identification of the Critical Site of Calponin 1 for Suppression of Ovarian Cancer Properties2015
- Author(s)
  Yamane T, Asanoma K, Kobayashi H, Liu G, Yagi H, Ohgami T, Ichinoe A, Sonoda K, Wake N, Kato K.
- Journal Title
  
  Anticancer Res
  
  Volume: 35 Pages: 5993-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861332
[Journal Article] Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma2015
- Author(s)
  Kiyokoba R, Yagi H, Yahata H, Kawano Y, Kaneki E, Okugawa K, Sonoda K, Kato K.
- Journal Title
  
  Case Rep Obstet Gynecol
  
  Volume: 352369 Pages: 1-6
- DOI
  10.1155/2015/352369
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861332
[Journal Article] Pre-clinical study of BK-UM, a novel inhibitor of HB-EGF, for ovarian cancer therapy.2014
- Author(s)
  Pre-clinical study of BK-UM, a novel inhibitor of HB-EGF, for ovarian cancer therapy. Nam SO, Yotsumoto F, Miyata K, Suzaki Y, Yagi H, Odawara T, Manabe S, Ishikawa T, Kuroki M, Mekada E, Miyamoto S.
- Journal Title
  
  Anticancer Res
  
  Volume: 34 Pages: 4615-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861332
[Journal Article] Pre-clinical study of BK-UM, a novel inhibitor of HB-EGF, for ovarian cancer therapy.2014
- Author(s)
  Nam SO, Yotsumoto F, Miyata K, Suzaki Y, Yagi H, Odawara T, Manabe S, Ishikawa T, Kuroki M, Mekada E, Miyamoto S
- Journal Title
  
  Anticancer Research
  
  Volume: 34 Pages: 4615-4620
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293362
[Journal Article] PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation2013
- Author(s)
  Milelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS
- Journal Title
  
  J Biol Chem
  
  Volume: 288(17) Pages: 12232-43
- Data Source
  KAKENHI-PROJECT-24791709
[Journal Article] 子宮頸癌を引き起こすヒトパピローマウイルスの発見/HPVの発見(2008年)2013
- Author(s)
  八木裕史、加藤聖子
- Journal Title
  
  Surgery Frontier
  
  Volume: 20(2) Pages: 19-23
- Data Source
  KAKENHI-PROJECT-24791709
[Journal Article] 子宮頸癌を引き起こすヒトパピローマウイルスの発見 /HPV の発見(2008年)2013
- Author(s)
  八木裕史 , 加藤聖子
- Journal Title
  
  Surgery Frontier
  
  Volume: 20(2) Pages: 19-23
- Data Source
  KAKENHI-PROJECT-24791709
[Journal Article] PDZ-RhoGEF and LARG are essential for embryo development, and provide a link between thrombin and LPA receptors and Rho activation2013
- Author(s)
  Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama Y, Bugge TH, Gutkind JS
- Journal Title
  
  J Biol Chem
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791709
[Journal Article] PDZ-RhoGEF and LARG are essential for embryo development, and provide a link between thrombin and LPA receptors and Rho activation.2013
- Author(s)
  Mikelis et al.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 17 Pages: 12232-12243
- DOI
  10.1074/jbc.m112.428599
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22113009, KAKENHI-PROJECT-22390040, KAKENHI-PROJECT-24791709, KAKENHI-PROJECT-25293050
[Journal Article] Clinical significance of amphiregulin and epidermal growth factor in colostrum2012
- Author(s)
  Nojiri T, Yoshizato T, Fukami T, Obama H, Yagi H, Yotsumoto F, Miyamoto S
- Journal Title
  
  Arch Gynecol Obstet
  
  Volume: 286 Pages: 643-647
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] Tumor-derived ARHGAP35 mutations enhance the Ga13-Rho signaling axis in human endometrial cancer2023
- Author(s)
  Hiroshi Yagi, Ichiro Onoyama, Kazuo Asanoma, Minoru Kawakami, Kazuhisa Hachisuga, Shoji Maenohara, Keisuke Kodama, Masafumi Yasunaga, Tatsuhiro Ohgami, Hideaki Yahata, Kiyoko Kato
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09496
[Presentation] Tumor-derived ARHGAP35 mutations enhance the Ga13-Rho signalling axis in human endometrial cancer2022
- Author(s)
  Hiroshi Yagi, Minoru Kawakami, Shoji Maenohara, Keisuke Kodama, Yumiko Matsumura, Ichiro Onoyama, Kazuo Asanoma, Kiyoko Kato
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09496
[Presentation] 三量体Ｇタンパクの機能解析に基づいた新たな婦人科がん治療の開発2022
- Author(s)
  八木裕史
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09496
[Presentation] Induction of AP-1 by Ga13 contributes to cell proliferation in human endometrial cancer2021
- Author(s)
  Hiroshi Yagi, Ichiro Onoyama, Kazuo Asanoma, Minoru Kawakami, Keisuke Kodama, Hiroshi Tomonobe, Nobuko Yasutake, Masafumi Yasunaga, Tatsuhiro Ohgami, Kaoru Okugawa, Hideaki Yahata, Kiyoko Kato
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09496
[Presentation] GEP oncogene induces epithelial-mesenchymal transition in ovarian cancer through LATS1 proteolysis2019
- Author(s)
  Hiroshi Yagi, Ichiro Onoyama, Kazuo Asanoma, Masafumi Yasunaga, Keisuke Kodama, Shusaku Inoue, Shinichiro Yamaguchi, Tatsuhiro Ohgami, Eisuke Kaneki, Kaoru Okugawa, Hideaki Yahata, Kiyoko Kato
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K11282
[Presentation] Ga13-mediated LATS1 down-regulation contributes to epithelial-mesenchymal transition in ovarian cancer2019
- Author(s)
  Hiroshi Yagi, Keisuke Kodama, Ichiro Onoyama, Kazuo Asanoma, Kiyoko Kato
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11282
[Presentation] GEP oncogene induces epithelial-mesenchymal transition through LATS1 degradation in ovarian cancer2018
- Author(s)
  Hiroshi Yagi, Keisuke Kodama, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Kenzo Sonoda, Kiyoko Kato
- Organizer
  第70回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K11282
[Presentation] GEP oncogene induces epithelial-mesenchymal transition through LATS1 degradation in ovarian cancer2018
- Author(s)
  Hiroshi Yagi, Ichiro Onoyama, Kazuo Asanoma, Keisuke Kodama, Kenzo Sonoda, Kiyoko Kato
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11282
[Presentation] The pivotal role of LATS1 in ovarian cancer progression2017
- Author(s)
  Yagi H, Kodama K, Yasunaga M, Ohgami T, Onoyama I, Asanoma K, Sonoda K, Kato K
- Organizer
  第69回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K11282
[Presentation] The G12/13-YAP signaling axis driving proliferation of ovarian cancer cells2015
- Author(s)
  Hiroshi Yagi, Kenzo Sonoda, Kiyoko Kato
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-26861332
[Presentation] 卵巣癌の進展におけるGEP oncogenes(Ga12、Ga13)の役割2014
- Author(s)
  八木裕史、園田顕三、小林裕明、加藤聖子
- Organizer
  第13回日本婦人科がん分子標的研究会
- Place of Presentation
  米子市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 難治性膀胱腟瘻に対する腹式修復時の介在組織として腹直筋弁を使用した一例2012
- Author(s)
  小林裕明, 八木裕史, 井上貴史, 河野善明, 兼城英輔, 奥川馨, 矢幡秀昭, 園田顕三, 和氣徳夫
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 卵巣癌腹膜播種に対するTatペプチドをベクターとしたカルポニンh1遺伝子治療の試み2012
- Author(s)
  山根敬子、小野山一郎、八木裕史、北出尚子、園田顕三、小林裕明、和氣徳夫
- Organizer
  日本産科婦人科学会　第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 癌の浸潤、転移におけるCXCR4/Ga13/Rhoシグナル経路の役割2012
- Author(s)
  八木裕史、園田顕三、小林裕明、和氣徳夫
- Organizer
  日本産科婦人科学会　第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 3mm以内の頸部間質浸潤に留まる子宮頸部腺癌Ib1期の術式は単純子宮全摘出術で十分か2012
- Author(s)
  矢幡秀昭、麻生佳愛、八木裕史、井上貴史、兼城英輔、河野善明、奥川馨、園田顕三、加来恒壽、小林裕明、和氣徳夫
- Organizer
  日本産科婦人科学会　第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 3mm以内の頸部間質浸潤に留まる子宮頸部腺癌 Ib1 期の術式は単純子宮全摘出術で十分か2012
- Author(s)
  矢幡秀昭, 麻生佳愛, 八木裕史, 井上貴史, 兼城英輔, 河野善明, 奥川馨, 園田顕三, 加来恒壽, 小林裕明, 和氣徳夫
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 難治性膀胱腟瘻に対する腹式修復時の介在組織として腹直筋弁を利用した一例2012
- Author(s)
  小林裕明、八木裕史、井上貴史、河野善明、兼城英輔、奥川馨、矢幡秀昭、園田顕三、和氣徳夫
- Organizer
  日本産科婦人科学会　第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 卵巣癌腹膜播種に対する Tat ペプチドをベクターとしたカルポニン h1 遺伝子治療の試み2012
- Author(s)
  山根敬子, 小野山一郎, 八木裕史, 北出尚子, 園田顕三, 小林裕明, 和気徳夫
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] 癌の浸潤, 転移における CXCR4/Gα_13 /Rho シグナル経路の役割2012
- Author(s)
  八木裕史, 園田顕三, 小林裕明, 和氣徳夫
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791709
[Presentation] The role of GEP oncogene, Ga12 and Ga13, in the progression of ovarian cancer
- Author(s)
  Yagi H, Sonoda K, Kato K
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861332
[Presentation] The role of GEP oncogene, Ga12 and Ga13, in the progression of ovarian cancer
- Author(s)
  Yagi H, Sonoda K, Kato K
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-26861332

1. Miyamoto Shingo (40209945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 鍋島一樹 (40189189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 四元房典 (40533089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. FUKAGAWA Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SONODA、KENZOU

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 加藤聖子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 浅野間和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yagi Hiroshi 八木 裕史

YAGI Hiroshi 八木 裕史

Research Projects

Research Products

Co-Researchers

細胞接着型GPCRの機能解析に基づく卵巣癌治療標的の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of heterotrimeric G protein in the progression of gynecological cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of Ga13 in the progression of gynecologic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Searching gene to manufacture the companion diagnostic agent targeting the HB-EGF.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of GPCR signaling in gynecologic cancer progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of GPCR signaling in the progression of gynecological cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gα13-mediated LATS1 down-regulation contributes to epithelial-mesenchymal transition in ovarian cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Uterine myxoid leiomyosarcoma with tumor embolism extending into the right atrium2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of the Critical Site of Calponin 1 for Suppression of Ovarian Cancer Properties2015

Author(s)

Journal Title

Data Source

[Journal Article] Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pre-clinical study of BK-UM, a novel inhibitor of HB-EGF, for ovarian cancer therapy.2014

Author(s)

Journal Title

Data Source

[Journal Article] Pre-clinical study of BK-UM, a novel inhibitor of HB-EGF, for ovarian cancer therapy.2014

Yagi Hiroshi 八木裕史

YAGI Hiroshi 八木裕史