Shigemura Tomonari 重村倫成

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SHIGEMURA Tomonari 重村倫成

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Researcher Number	70623916
Affiliation (Current)	2025: 信州大学, 医学部, 特任講師
Affiliation (based on the past Project Information) *help	2017 – 2019: 信州大学, 学術研究院医学系(医学部附属病院), 講師 2014 – 2016: 信州大学, 学術研究院医学系, 助教 2014 – 2015: 信州大学, 医学部, 助教 2013: 信州大学, 医学部, 助教(受託研究) 2012: 信州大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator 慢性肉芽腫症 / 炎症 / 先天性免疫不全症 / 好中球 / 保因者 / 殺菌蛋白 / PPARγ / 獲得免疫 / 腸炎 / 肉芽腫 … More / 活性酸素 / 免疫不全 / 真菌特異的Ｔ細胞 / 接合菌特異的PCR / 真菌 / 接合菌 / 接合菌溶菌液 / 養子免疫療法 / 接合菌特異的T細胞 / 免疫不全症 / 造血幹細胞移植 / 接合菌血清診断 / 養子免疫 / 接合菌症 / 遺伝子治療 / PiggyBac / トランスポゾン / iPS細胞 … More Except Principal Investigator 先天性食細胞異常症 / 白血病発症 / 再生医学 / 遺伝子治療 / 先天性好中球減少症 / ゲノム修飾 / iPS細胞 / SNP array / SNA array / 上衣腫 Less

Elucidation and novel therapies development for granuloma formation in chronic granulomatous diseasePrincipal Investigator
- Principal Investigator
  
  Shigemura Tomonari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Development of a gene therapy for congenital phagocyte disorder using both genome editing and iPS cell technology
- Principal Investigator
  
  Koike Kenichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Classification of ependymoma of childhood and establishment of molecular diagnositic procedure for molecular target therapy of ependymoma.
- Principal Investigator
  
  Shiohara Masaaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Matsumoto Dental University
Development of the specific adoptive immunotherapy for the invasive mucormycosisPrincipal Investigator
- Principal Investigator
  
  SHIGEMURA Tomonari
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Development of new gene therapy for chronic granulomatous disease using Piggyback transposonPrincipal Investigator
- Principal Investigator
  
  SHIGEMURA Tomonari
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Early-onset inflammatory bowel disease caused by mutations in the X-linked gene IL2RG Journal of Investigational Allergology and Clinical Immunology2021
- Author(s)
  Akio Ogawa, Tatsuo Watanabe, Takenori Natsume, Eri Okura, Shoji Saito, Sawako Kato, Yoshiko Nakayama, Satomi Furukawa, Tomomi Yamaguchi, Tomoki Kosho, Takeshi Uehara, Norimoto Kobayashi, Kazunaga Agematsu, Yozo Nakazawa, Tomonari Shigemura
- Journal Title
  
  Journal of Investigational Allergology and Clinical Immunology
  
  Volume: 31 Issue: 1 Pages: 69-71
- DOI
  10.18176/jiaci.0523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10104
[Journal Article] Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation2020
- Author(s)
  Shigemura T, Sakashita K, Okura E, Morita D, Komori K, Kurata T, Hirabayashi K, Saito S, Tanaka M, Yanagisawa R, Nakazawa Y. Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
- Journal Title
  
  Int J Hematol
  
  Volume: 111 Issue: 5 Pages: 702-710
- DOI
  10.1007/s12185-020-02826-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10021, KAKENHI-PROJECT-17K10104, KAKENHI-PROJECT-17K10105, KAKENHI-PROJECT-20K08227
[Journal Article] 原発性免疫不全症候群の遺伝カウンセリング2019
- Author(s)
  重村倫成
- Journal Title
  
  小児科
  
  Volume: 60 Pages: 1268-1272
- Data Source
  KAKENHI-PROJECT-17K10104
[Journal Article] Mosaicism of an ELANE Mutation in an Asymptomatic Mother.2019
- Author(s)
  Shigemura T, Kobayashi N, Agematsu K, Ohara O, Nakazawa Y.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 39(1) Issue: 1 Pages: 106-111
- DOI
  10.1007/s10875-018-0580-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10104
[Journal Article] Bacteremia due to Moraxella osloensis : a case report and literature review2018
- Author(s)
  Maruyama Yuta、Shigemura Tomonari、Aoyama Koki、Nagano Noriyuki、Nakazawa Yozo
- Journal Title
  
  The Brazilian Journal of Infectious Diseases
  
  Volume: 22 Issue: 1 Pages: 60-62
- DOI
  10.1016/j.bjid.2017.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10104
[Journal Article] Panobinostat inhibits the proliferation of CD34+CD38－cells under stimulation of hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia.2018
- Author(s)
  Kurata, T, Matsuda K, Hirabayashi K, Shigemura T, Sakashita K, Nakahata T, Koike K.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 印刷中 Issue: 11
- DOI
  10.1002/pbc.27261
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] 好中球機能異常症2017
- Author(s)
  丸山悠太, 重村倫成
- Journal Title
  
  小児科診療
  
  Volume: 80 Pages: 1211-1216
- Data Source
  KAKENHI-PROJECT-17K10104
[Journal Article] Acute Myeloid Leukemia in a Patient With X-linked Severe Combined Immunodeficiency2017
- Author(s)
  Shigemura Tomonari、Motobayashi Mitsuo、Matsuda Kazuyuki、Shimodaira Takahiro、Kurata Takashi、Kobayashi Norimoto、Agematsu Kazunaga、Nakazawa Yozo
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 39 Issue: 8 Pages: e470-e472
- DOI
  10.1097/mph.0000000000000892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10104
[Journal Article] Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.2017
- Author(s)
  Watanabe T, Kurata T, Sano K, Suzuki S, Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K, Nakazawa Y.
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 39 Pages: 154-156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Dramatic Reduction in Tumor Size During 5 Months of Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.2017
- Author(s)
  Watanabe T, Kurata T, Sano K, Suzuki S, Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K, Nakazawa Y
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 39 Issue: 2 Pages: 154-6
- DOI
  10.1097/mph.0000000000000628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Early detection of Rhizopus DNA in the serum of a patient with rhino-orbital-cerebral mucormycosis following allogeneic hematopoietic stem cell transplantation.2016
- Author(s)
  Shigemura T, Nishina S, Nakazawa H, Matsuda K, Yaguchi T, Nakazawa Y.
- Journal Title
  
  Int J Hematol.
  
  Volume: 103 Issue: 3 Pages: 354-5
- DOI
  10.1007/s12185-016-1938-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860791
[Journal Article] Viral load and ganciclovir (GCV) concentration in cerebrospinal fluid of patients successfully treated with GCV or valGCV for human herpesvirus 6 encephalitis/myelitis following umbilical cord blood transplantation.2016
- Author(s)
  D. Morita, K. Hirabayashi, Y. Katsuyama, H. Morokawa, M. Motobayashi, T. Kurata, T. Shigemura, M. Tanaka, Y. Inaba, K. Koike, Y. Nakazawa.
- Journal Title
  
  Transpl Infect Dis
  
  Volume: 18 Issue: 5 Pages: 773-776
- DOI
  10.1111/tid.12579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction.2016
- Author(s)
  Hirabayashi K, Kurata T, Horiuchi K, Saito S, Shigemura T, Tanaka M, Yanagisawa R, Matsuda K, Sakashita K, Koike K, Nakazawa Y
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 63 Issue: 4 Pages: 709-11
- DOI
  10.1002/pbc.25819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874, KAKENHI-PROJECT-26860789
[Journal Article] Dramatic Improvement in the Multifocal Positron Emission Tomography Findings of a Young Adult with Chronic Granulomatous Disease Following Allogeneic Hematopoietic Stem Cell Transplantation.2015
- Author(s)
  Shigemura T, Nakazawa Y, Hirabayashi K, Kobayashi N, Sakashita K, Agematsu K, Koike K.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 35 Pages: 84-86
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860791
[Journal Article] Subcutaneous abscess due to the basidiomycete Phellinus mori in a patient with chronic granulomatous disease.2015
- Author(s)
  Shigemura T, Nakazawa Y, Amano Y, Sudo A, Watanabe M, Kobayashi M, Kobayashi N, Koike K, Agematsu K, Nishimura K.
- Journal Title
  
  Infection
  
  Volume: Jan 20
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860791
[Journal Article] Subcutaneous abscess due to the basidiomycete Phellinus mori in a patient with chronic granulomatous disease.2015
- Author(s)
  Shigemura T, Nakazawa Y, Amano Y, Sudo A, Watanabe M, Kobayashi M, Kobayashi N, Koike K, Agematsu K, Nishimura K.
- Journal Title
  
  Infection
  
  Volume: 43 Issue: 3 Pages: 371-5
- DOI
  10.1007/s15010-015-0724-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Dramatic improvement in the multifocal positron emission tomography findings of a young adult with chronic granulomatous disease following allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  Shigemura T, Nakazawa Y, Hirabayashi K, Kobayashi N, Sakashita K, Agematsu K, Koike K.
- Journal Title
  
  J Clin Immunol
  
  Volume: 35 Issue: 1 Pages: 84-6
- DOI
  10.1007/s10875-014-0113-5
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Evaluation of Mucorales DNA load in cerebrospinal fluid in a patient with possible cerebral mucormycosis treated with intravenous liposomal amphotericin B.2014
- Author(s)
  Shigemura T, Nakazawa Y, Matsuda K, Motobayashi M, Saito S, Koike K.
- Journal Title
  
  Int J Infect Dis.
  
  Volume: 29 Pages: 200-2
- DOI
  10.1016/j.ijid.2014.10.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860791
[Presentation] Early-onset inflammatory bowel disease in a patient with X-linked severe combined immunodeficiency2019
- Author(s)
  Tomonari Shigemura, Akio Ogawa, Tatsuo Watanabe, Takenori Natsume, Eri Okura, Shoji Saito, Sawako Kato, Yoshiko Nakayama, Satomi Furukawa, Tomomi Yamaguchi, Tomoki Kosho, Takeshi Uehara, Norimoto Kobayashi, Kazunaga Agematsu, Yozo Nakazawa
- Organizer
  The European Society for Immunodeficiencies (ESID 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10104
[Presentation] 重症先天性好中球減少症責任遺伝子ELANE変異を認めた無症候性母親の解析2018
- Author(s)
  重村倫成、小林法元、上松一永、中沢洋三、小原収
- Organizer
  第1回日本免疫不全・自己炎症学会
- Data Source
  KAKENHI-PROJECT-15H04874
[Presentation] 重症先天性好中球減少症責任遺伝子ELANE変異を認めた無症候性母親の解析2018
- Author(s)
  重村倫成、小林法元、上松一永、中沢洋三、小原収
- Organizer
  第1回日本免疫不全・自己炎症学会
- Data Source
  KAKENHI-PROJECT-17K10104
[Presentation] 臍帯血移植後の輸血関連サイトメガロウイルス血症の検討2018
- Author(s)
  重村倫成、小森一寿、盛田大介、平林耕一、倉田敬、齋藤章治、田中美幸、柳沢龍、坂下一夫、中沢洋三
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-15H04874
[Presentation] A novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal dominant Behcet’s disease2017
- Author(s)
  Shigemura T, Kobayashi N, Kobayashi K, Agematsu K
- Organizer
  第60回小児リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15H04874
[Presentation] Mosaic ELANE mutation causing severe congenital neutropenia in an asymptomatic mother2017
- Author(s)
  Tomonari Shigemura, Norimoto Kobayashi, Kazunaga Agematsu, Yozo Nakazawa
- Organizer
  The 18th Meeting of the European Society for Immunodeficiencies (ESID 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10104
[Presentation] 接合菌特異的定量PCRによる血清診断法の確立骨髄移植後早期に播種性接合菌症を来したp67phox欠損型慢性肉芽腫症症例での検討　慢性肉芽腫症に対する新たな戦略の試み2014
- Author(s)
  重村倫成
- Organizer
  平成25年度　班会議　厚生労働省難治性疾患克服研究事業
- Place of Presentation
  九州大学コラボステーションI
- Data Source
  KAKENHI-PROJECT-24791049
[Presentation] PiggyBacトランスポゾンとiPS技術を組み合わせた慢性肉芽腫症に対する新たな遺伝子治療の開発2013
- Author(s)
  重村倫成
- Organizer
  第116回日本小児学術集会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-24791049
[Presentation] PiggyBacトランスポゾンとiPS技術を組み合わせた慢性肉芽腫症に対する新たな遺伝子治療の開発2012
- Author(s)
  重村倫成
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24791049
[Presentation] PiggyBac トランスポゾンとiPS 技術を組み合わせた慢性肉芽腫症に対する新たな遺伝子治療の開発2012
- Author(s)
  重村倫成, 中沢洋三, 松田和之, 小池健一
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡国際会議場 4F 401-403会議室(第4会場)
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-24791049

1. Shiohara Masaaki (00293514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Koike Kenichi (40143979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 中沢洋三 (60397312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 柳沢龍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shigemura Tomonari 重村 倫成

SHIGEMURA Tomonari 重村 倫成

Research Projects

Research Products

Co-Researchers

Elucidation and novel therapies development for granuloma formation in chronic granulomatous diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a gene therapy for congenital phagocyte disorder using both genome editing and iPS cell technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Classification of ependymoma of childhood and establishment of molecular diagnositic procedure for molecular target therapy of ependymoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the specific adoptive immunotherapy for the invasive mucormycosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new gene therapy for chronic granulomatous disease using Piggyback transposonPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Early-onset inflammatory bowel disease caused by mutations in the X-linked gene IL2RG Journal of Investigational Allergology and Clinical Immunology2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 原発性免疫不全症候群の遺伝カウンセリング2019

Author(s)

Journal Title

Data Source

[Journal Article] Mosaicism of an ELANE Mutation in an Asymptomatic Mother.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bacteremia due to Moraxella osloensis : a case report and literature review2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Panobinostat inhibits the proliferation of CD34+CD38－cells under stimulation of hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 好中球機能異常症2017

Author(s)

Journal Title

Data Source

[Journal Article] Acute Myeloid Leukemia in a Patient With X-linked Severe Combined Immunodeficiency2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.2017

Author(s)

Journal Title

Data Source

[Journal Article] Dramatic Reduction in Tumor Size During 5 Months of Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.2017

Author(s)

Journal Title

Shigemura Tomonari 重村倫成

SHIGEMURA Tomonari 重村倫成

[Presentation] 接合菌特異的定量PCRによる血清診断法の確立骨髄移植後早期に播種性接合菌症を来したp67phox欠損型慢性肉芽腫症症例での検討　慢性肉芽腫症に対する新たな戦略の試み2014