Higashimura Yasuki 東村泰希

Researcher Number	70628924
Other IDs
Affiliation (Current)	2025: 石川県立大学, 生物資源環境学部, 准教授 2025: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help	2017 – 2024: 石川県立大学, 生物資源環境学部, 准教授 2016 – 2017: 石川県立大学, 生物資源環境学部, 助教 2013 – 2015: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Eating habits Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 炎症性腸疾患 / 大腸がん / bach1 / 腸内細菌叢 / レクチン / 杯細胞 / Bach1 / 糖鎖 / ムチン / ゴブレット細胞 … More / リンパ球 / インターロイキン-13 / Th17 / マクロファージ / 大腸炎 / 亜鉛 / PPARa / MAPキナーゼ / PPARalpha / 大腸 / プロピオン酸 / 短鎖脂肪酸 … More Except Principal Investigator リキッドバイオプシー / ペプチド分析 / 先制医療 / 質量分析計 / ペプチドマーカー / 質量分析 / ペプチド / 早期発見 / バイオマーカー / 大腸癌 Less

大腸がん予防を目的としたO型糖鎖異常に関する分子機序の解明Principal Investigator
- Principal Investigator
  
  東村泰希
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ishikawa Prefectural University
Involvement of the transcriptional repressor Bach1 in the maintenance of colonic mucusPrincipal Investigator
- Principal Investigator
  
  Higashimura Yasuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ishikawa Prefectural University
Involvement of transcription repressor Bach1 in colonic mucous secretionPrincipal Investigator
- Principal Investigator
  
  Higashimura Yasuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ishikawa Prefectural University
Precision Medicine for Colon Cancer by High-throughput Analysis by Quantitative Mass Spectrometry
- Principal Investigator
  
  Naito Yuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Identification of novel zinc-responsive protein and clarification of significance in colorectal cancer preventionPrincipal Investigator
- Principal Investigator
  
  HIGASHIMURA YASUKI
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Ishikawa Prefectural University
Evaluation a novel molecular mechanism of protecting colon cancer by the foo-derived componentsPrincipal Investigator
- Principal Investigator
  
  Higashimura Yasuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Kyoto Prefectural University of Medicine

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Heme Oxygenase-1 Induction Inhibits Intestinal Inflammation. in "Clinical Aspects of Functional Foods and Neutraceuticals"2014
- Author(s)
  Naito, Y., Takagi, T., Harusato, A., Higashimura, Y., and Yoshikawa, T.
- Total Pages
  474
- Publisher
  CRC press
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] Prebiotic effect of galacto- N -biose on the intestinal lactic acid bacteria as enhancer of acetate production and hypothetical colonization2024
- Author(s)
 Matsuzaki Chiaki、Takagi Hiroki、Saiga Sorachi、Kinoshita Yuun、Yamaguchi Misako、Higashimura Yasuki、Yamamoto Kenji、Yamaguchi Masanori
- Journal Title
 
 Applied and Environmental Microbiology
 
 Volume: -
- DOI
 10.1128/aem.01445-23
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K05471
[Journal Article] D-alanine Inhibits Murine Intestinal Inflammation by Suppressing IL-12 and IL-23 Production in Macrophages2024
- Author(s)
  Hashimoto Hikaru、Takagi Tomohisa、Asaeda Kohei、Yasuda Takeshi、Kajiwara Mariko、Sugaya Takeshi、Mizushima Katsura、Inoue Ken、Uchiyama Kazuhiko、Kamada Kazuhiro、Higashimura Yasuki、Inoue Ryo、Naito Yuji、Itoh Yoshito
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: - Issue: 6 Pages: 908-919
- DOI
  10.1093/ecco-jcc/jjad217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05471
[Journal Article] Activity difference of three labdane diterpenoids on human constitutive androstane receptor2023
- Author(s)
  Sekiguchi Mitsuhiro、Fujinami Yui、Takado Keiyu、Kimoto Yuu、Higashimura Yasuki
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 87 Issue: 11 Pages: 1310-1315
- DOI
  10.1093/bbb/zbad113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06664, KAKENHI-PROJECT-21K05471
[Journal Article] Water‐soluble dietary fiber alleviates cancer‐induced muscle wasting through changes in gut microenvironment in mice2022
- Author(s)
  Sakakida Tomoki、Ishikawa Takeshi、Doi Toshifumi、Morita Ryuichi、Endo Yuki、Matsumura Shinya、Ota Takayuki、Yoshida Juichiro、Hirai Yasuko、Mizushima Katsura、Higashimura Yasuki、Inoue Ken、Okayama Tetsuya、Uchiyama Kazuhiko、Takagi Tomohisa、Abe Aya、Inoue Ryo、Itoh Yoshito、Naito Yuji
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 5 Pages: 1789-1800
- DOI
  10.1111/cas.15306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05471, KAKENHI-PROJECT-20K07787
[Journal Article] Streptococcus thermophilus extends lifespan through activation of DAF-16-mediated antioxidant pathway in Caenorhabditis elegans2022
- Author(s)
 Desaka Natsumi、Ota Chinatsu、Nishikawa Hitomi、Yasuda Kayo、Ishii Naoaki、Bito Tomohiro、Kishinaga Yukio、Naito Yuji、Higashimura Yasuki
- Journal Title
 
 Journal of Clinical Biochemistry and Nutrition
 
 Volume: 70 Issue: 1 Pages: 7-13
- DOI
 10.3164/jcbn.21-56
- NAID
 130008139109
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K05471
[Journal Article] Lycopene intake induces colonic regulatory T cells in mice and suppresses food allergy symptoms.2022
- Author(s)
  Ushiroda C, Takagi T, Fuke N, Mizushima K, Hirai Y, Higashimura Y, Harusato A, Kamada K, Uchiyama K, Ishikawa T, Aizawa K, Suganuma H, Itoh Y, Naito Y.
- Journal Title
  
  Pediatr Allergy Immunol.
  
  Volume: 33 Issue: 1
- DOI
  10.1111/pai.13691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08292, KAKENHI-PROJECT-21K05471, KAKENHI-PROJECT-20K19672
[Journal Article] Oligosaccharides from agar extends lifespan through activation of unfolded protein response via SIR-2.1 in Caenorhabditis elegans2022
- Author(s)
  Desaka Natsumi、Nishikawa Hitomi、Honda Yuji、Matsumoto Kenji、Matsuzaki Chiaki、Mizushima Katsura、Takagi Tomohisa、Naito Yuji、Higashimura Yasuki
- Journal Title
  
  European Journal of Nutrition
  
  Volume: 61 Issue: 8 Pages: 4179-4190
- DOI
  10.1007/s00394-022-02957-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05471
[Journal Article] Red-Beet Betalain Pigments Inhibit Amyloid-β Aggregation and Toxicity in Amyloid-β Expressing Caenorhabditis elegans2022
- Author(s)
  Imamura Tomohiro、Isozumi Noriyoshi、Higashimura Yasuki、Koga Hironori、Segawa Tenta、Desaka Natsumi、Takagi Hiroki、Matsumoto Kenji、Ohki Shinya、Mori Masashi
- Journal Title
  
  Plant Foods for Human Nutrition
  
  Volume: 77 Issue: 1 Pages: 90-97
- DOI
  10.1007/s11130-022-00951-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05471
[Journal Article] Role of Lipoteichoic Acid from the Genus Apilactobacillus in Inducing a Strong IgA Response2022
- Author(s)
 Matsuzaki Chiaki、Shiraishi Tsukasa、Chiou Tai-Ying、Nakashima Yukari、Higashimura Yasuki、Yokota Shin-ichi、Yamamoto Kenji、Takahashi Tomoya
- Journal Title
 
 Applied and Environmental Microbiology
 
 Volume: 88 Issue: 8
- DOI
 10.1128/aem.00190-22
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K05471, KAKENHI-PROJECT-20H03488
[Journal Article] Rectal administration of carbon monoxide inhibits the development of intestinal inflammation and promotes intestinal wound healing via the activation of the Rho-kinase pathway in rats.2021
- Author(s)
  Takagi T, Naito Y, Higashimura Y, Uchiyama K, Okayama T, Mizushima K, Katada K, Kamada K, Ishikawa T, Itoh Y.
- Journal Title
  
  Nitric Oxide.
  
  Volume: 107 Pages: 19-30
- DOI
  10.1016/j.niox.2020.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08292, KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Identification of colorectal neoplasia by using serum bile acid profile2021
- Author(s)
  Uchiyama Kazuhiko、Naito Yuji、Yagi Nobuaki、Mizushima Katsura、Higashimura Yasuki、Hirai Yasuko、Dohi Osamu、Okayama Tetsuya、Yoshida Naohisa、Katada Kazuhiro、Kamada Kazuhiro、Ishikawa Takeshi、Takagi Tomohisa、Konishi Hideyuki、Kuriu Yoshiaki、Nakanishi Masayoshi、Otsuji Eigo、Honda Akira、Itoh Yoshito
- Journal Title
  
  Biomarkers
  
  Volume: - Issue: 5 Pages: 1-6
- DOI
  10.1080/1354750x.2021.1917663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Enzymatically synthesized exopolysaccharide of a probiotic strain Leuconostoc mesenteroides NTM048 shows adjuvant activity to promote IgA antibody responses2021
- Author(s)
 Matsuzaki Chiaki、Nakashima Yukari、Endo Ikuto、Tomabechi Yusuke、Higashimura Yasuki、Itonori Saki、Hosomi Koji、Kunisawa Jun、Yamamoto Kenji、Hisa Keiko
- Journal Title
 
 Gut Microbes
 
 Volume: 13 Issue: 1
- DOI
 10.1080/19490976.2021.1949097
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K05471
[Journal Article] Production of ORF8 protein from SARS-CoV-2 using an inducible virus-mediated expression system in suspension-cultured tobacco BY-2 cells2021
- Author(s)
  Imamura Tomohiro、Isozumi Noriyoshi、Higashimura Yasuki、Ohki Shinya、Mori Masashi
- Journal Title
  
  Plant Cell Reports
  
  Volume: 40 Issue: 3 Pages: 433-436
- DOI
  10.1007/s00299-020-02654-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475
[Journal Article] Dietary intake of yacon roots (Smallanthus sonchifolius) affects gut microbiota and fecal mucin and prevents intestinal inflammation in mice2021
- Author(s)
 Higashimura Yasuki、Hirabayashi Misaki、Nishikawa Hitomi、Inoue Ryo、Nagai Emiko、Matsumoto Kenji、Enomoto Toshiki、Mizushima Katsura、Takagi Tomohisa、Naito Yuji
- Journal Title
 
 Journal of Clinical Biochemistry and Nutrition
 
 Volume: 69 Issue: 3 Pages: 272-279
- DOI
 10.3164/jcbn.20-203
- NAID
 130008110248
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K05471
[Journal Article] The effects of ingestion of hydrogen-dissolved alkaline electrolyzed water on stool consistency and gut microbiota: a double-blind randomized trial2021
- Author(s)
  Tanaka Yoshinori、Kiuchi Masataka、Higashimura Yasuki、Naito Yuji、Koyama Katsuhiro
- Journal Title
  
  Medical Gas Research
  
  Volume: 11 Issue: 4 Pages: 138-138
- DOI
  10.4103/2045-9912.318858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05471
[Journal Article] Trans-unsaturated fatty acid activates NLRP3 inflammasome in macrophages and exacerbates intestinal inflammation in mice2020
- Author(s)
  Higashimura Yasuki、Tanaka Yumiko、Takagi Tomohisa、Uchiyama Kazuhiko、Mizushima Katsura、Niki Etsuo、Naito Yuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 2 Pages: 243-250
- DOI
  10.1016/j.bbrc.2020.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Administration of Enterococcus faecium HS-08 increases intestinal acetate and induces immunoglobulin A secretion in mice2020
- Author(s)
  Fujita Saki、Baba Yasunori、Nakashima Yukari、Higashimura Yasuki、Yamamoto Kenji、Matsuzaki Chiaki、Kawagishi Minoru
- Journal Title
  
  Canadian Journal of Microbiology
  
  Volume: 66 Issue: 10 Pages: 576-585
- DOI
  10.1139/cjm-2020-0020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475
[Journal Article] Cholestyramine, a Bile Acid Sequestrant, Increases Cecal Short Chain Fatty Acids and Intestinal Immunoglobulin A in Mice2020
- Author(s)
  Nishida Saki、Horinouchi Ayumu、Higashimura Yasuki、Akahori Reina、Matsumoto Kenji
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 3 Pages: 565-568
- DOI
  10.1248/bpb.b19-00923
- NAID
  130007804467
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475
[Journal Article] Zinc Deficiency Activates the IL-23/Th17 Axis to Aggravate Experimental Colitis in Mice2019
- Author(s)
  Higashimura Yasuki、Takagi Tomohisa、Naito Yuji、Uchiyama Kazuhiko、Mizushima Katsura、Tanaka Makoto、Hamaguchi Masahide、Itoh Yoshito
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: - Issue: 6 Pages: 856-866
- DOI
  10.1093/ecco-jcc/jjz193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice2019
- Author(s)
  Takagi T, Homma T, Fujii J, Shirasawa N, Yoriki H, Hotta Y, Higashimura Y, Mizushima K, Hirai Y, Katada K, Uchiyama K, Naito Y, Itoh Y.
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 134 Pages: 153-164
- DOI
  10.1016/j.freeradbiomed.2018.12.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-18K06224
[Journal Article] Combined treatment of dipeptidyl peptidase‐4 inhibitor and exercise training improves lipid profile in KK/Ta mice2019
- Author(s)
  Tanimura Yuko、Aoi Wataru、Mizushima Katsura、Higashimura Yasuki、Naito Yuji
- Journal Title
  
  Experimental Physiology
  
  Volume: 104 Issue: 7 Pages: 1051-1060
- DOI
  10.1113/ep087449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-17H02176
[Journal Article] Green tea polyphenol (epigallocatechin-3-gallate) improves gut dysbiosis and serum bile acids dysregulation in high-fat diet-fed mice2019
- Author(s)
  Ushiroda Chihiro、Naito Yuji、Takagi Tomohisa、Uchiyama Kazuhiko、Mizushima Katsura、Higashimura Yasuki、Yasukawa Zenta、Okubo Tsutomu、Inoue Ryo、Honda Akira、Matsuzaki Yasushi、Itoh Yoshito
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 65 Issue: 1 Pages: 34-46
- DOI
  10.3164/jcbn.18-116
- NAID
  130007672107
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Lactobacillus brevis KB290 With Vitamin A Ameliorates Murine Intestinal Inflammation Associated With the Increase of CD11c+ Macrophage/CD103? Dendritic Cell Ratio2018
- Author(s)
  Fuke Nobuo、Takagi Tomohisa、Higashimura Yasuki、Tsuji Toshifumi、Umeda Ryohei、Mizushima Katsura、Tanaka Makoto、Suganuma Hiroyuki、Aizawa Koichi、Yajima Nobuhiro、Naito Yuji
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 24 Issue: 2 Pages: 317-331
- DOI
  10.1093/ibd/izx003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16281
[Journal Article] Mucus reduction promotes acetyl salicylic acid-induced small intestinal mucosal injury in rats2018
- Author(s)
  Suyama Y, Handa O, Naito Y, Takayama S, Mukai R, Ushiroda C, Majima A, Yasuda-Onozawa Y, Higashimura Y, Fukui A, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 498 Issue: 1 Pages: 228-233
- DOI
  10.1016/j.bbrc.2018.02.202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475
[Journal Article] Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4(+) T cells.2018
- Author(s)
  Tanaka M, Takagi T, Naito Y, Uchiyama K, Hotta Y, Toyokawa Y, Ushiroda C, Hirai Y, Aoi W, Higashimura Y, Mizushima K, Okayama T, Katada K, Kamada K, Ishikawa T, Handa O, Itoh Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 33 Issue: 3 Pages: 671-680
- DOI
  10.1111/jgh.13842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-16H05289, KAKENHI-PROJECT-16K16281, KAKENHI-PROJECT-17H02176
[Journal Article] Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice2018
- Author(s)
  Higashimura Yasuki、Baba Yasunori、Inoue Ryo、Takagi Tomohisa、Uchiyama Kazuhiko、Mizushima Katsura、Hirai Yasuko、Ushiroda Chihiro、Tanaka Yoshinori、Naito Yuji
- Journal Title
  
  Medical Gas Research
  
  Volume: 8 Issue: 1 Pages: 6-6
- DOI
  10.4103/2045-9912.229597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16281
[Journal Article] Immunostimulatory effect on dendritic cells of the adjuvant-active exopolysaccharide from Leuconostoc mesenteroides strain NTM0482018
- Author(s)
  Matsuzaki C, Takagaki C, Higashimura Y, Nakashima Y, Hosomi K, Kunisawa J, Yamamoto K, Hisa K.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 82 Issue: 9 Pages: 1647-1651
- DOI
  10.1080/09168451.2018.1482195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K17997, KAKENHI-PROJECT-18J00556
[Journal Article] Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP((R))-MS analysis2018
- Author(s)
  Uchiyama, K. Naito, Y. Yagi, N. Mizushima, K. Higashimura, Y. Hirai, Y. Dohi, O. Okayama, T. Yoshida, N. Katada, K. Kamada, K. Handa, O. Ishikawa, T. Takagi, T. Konishi, H. Nonaka, D. Asada, K. Lee, L. J. Tanaka, K. Kuriu, Y. Nakanishi, M. Otsuji, E. Itoh, Y.
- Journal Title
  
  J Gastroenterol
  
  Volume: 印刷中 Issue: 11 Pages: 1179-1185
- DOI
  10.1007/s00535-018-1448-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05289, KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 42018
- Author(s)
  Hotta Y, Uchiyama K, Takagi T, Kashiwagi S, Nakano T, Mukai R, Toyokawa Y, Yasuda T, Ueda T, Suyama Y, Murakami T, Tanaka M, Majima A, Doi T, Hirai Y, Mizushima K, Morita M, Higashimura Y, Inoue K, Fukui A, Okayama T, Katada K, Kamada K, Handa O, Ishikawa T, Naito Y, Itoh Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 506 Issue: 3 Pages: 557-562
- DOI
  10.1016/j.bbrc.2018.10.116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475
[Journal Article] Serum metabolomics analysis for early detection of colorectal cancer2017
- Author(s)
  Kazuhiko Uchiyama, Nobuaki Yagi, Katsura Mizushima, Yasuki Higashimura, Yasuko Hirai, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Osamu Handa, Takeshi Ishikawa, Tomohisa Takagi, Hideyuki Konishi, Yoshiaki Kuriu, Masayoshi Nakanishi, Eigo Otsuji, Yoshito Itoh, Yuji Naito
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 52(6) Issue: 6 Pages: 677-694
- DOI
  10.1007/s00535-016-1261-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08313, KAKENHI-PROJECT-16H05289
[Journal Article] Prevention of colitis by controlled oral drug delivery of carbon monoxide.2016
- Author(s)
  Steiger C, Uchiyama K, Takagi T, Mizushima K, Higashimura Y, Gutmann M, Hermann C, Botov S, Schmalz HG, Naito Y, Meinel L.
- Journal Title
  
  J Control Release.
  
  Volume: 239 Pages: 128-36
- DOI
  10.1016/j.jconrel.2016.08.030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-16K16281
[Journal Article] Zinc and gastrointestinal disorders2016
- Author(s)
  Higashimura Y, Takagi T, Naito Y.
- Journal Title
  
  Nihon Rinsho.
  
  Volume: 74(7) Pages: 1121-1125
- NAID
  40020885811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16281
[Journal Article] Partially hydrolysed guar gum ameliorates murine intestinal inflammation in association with modulating luminal microbiota and SCFA.2016
- Author(s)
  Takagi T, Naito Y, Higashimura Y, Ushiroda C, Mizushima K, Ohashi Y, Yasukawa Z, Ozeki M, Tokunaga M, Okubo T, Katada K, Kamada K, Uchiyama K, Handa O, Itoh Y, Yoshikawa
- Journal Title
  
  Br. J. Nutr.
  
  Volume: 116(7) Pages: 1199-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16281
[Journal Article] Protective effect of agaro-oligosaccharides on gut dysbiosis and colon tumorigenesis in high-fat diet-fed mice2016
- Author(s)
  Higashimura Y, Naito Y, Takagi T, Uchiyama K, Mizushima K, Ushiroda C, Ohnogi H, Kudo Y, Yasui M, Inui S, Hisada T, Honda A, Matsuzaki Y, Yoshikawa T
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol.
  
  Volume: 310 Issue: 6 Pages: G367-G375
- DOI
  10.1152/ajpgi.00324.2015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461022, KAKENHI-PROJECT-25750050, KAKENHI-PROJECT-16K16281
[Journal Article] 寒天由来のオリゴ糖：アガロオリゴ糖の機能性について．2016
- Author(s)
  東村泰希・大野木宏・内藤裕二
- Journal Title
  
  食品加工技術
  
  Volume: 36(1) Pages: 8-18
- NAID
  40020748548
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] Partially hydrolyzed guar gum enhances colonic epithelial wound healing via activation of RhoA and ERK1/2.2016
- Author(s)
  Horii Y, Uchiyama K, Toyokawa Y, Hotta Y, Tanaka M, Yasukawa Z, Tokunaga M, Okubo T, Mizushima K, Higashimura Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Naito Y, Itoh Y
- Journal Title
  
  Food Funct.
  
  Volume: 8(7) Issue: 7 Pages: 3176-3183
- DOI
  10.1039/c6fo00177g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16281
[Journal Article] pVHL-mediated degradation of HIF-2α regulates estrogen receptor α expression in normoxic breast cancer cells.2016
- Author(s)
  Higashimura Y, Kitakaze T, Harada N, Inui H, Nakano Y, Yamaji R.
- Journal Title
  
  FEBS Lett.
  
  Volume: 590 Issue: 16 Pages: 2690-2699
- DOI
  10.1002/1873-3468.12265
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26292073, KAKENHI-PROJECT-16K16281
[Journal Article] The therapeutic potential of zinc sulfate on inflammatory bowel diseases.2015
- Author(s)
  Higashimura, Y., Naito, Y., Takagi, T., Mizushima, K., and Yoshikawa, T.
- Journal Title
  
  Ulcer Res.
  
  Volume: 42 Pages: 4-4
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] 亜鉛は酸化型／還元型マクロファージの形質分化制御を介して腸管炎症を抑制する．2015
- Author(s)
  東村泰希・内藤裕二・髙木智久・内山和彦・水島かつら・吉川敏一
- Journal Title
  
  G.I. Research
  
  Volume: 23(4) Pages: 92-93
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] 非ステロイド性抗炎症薬惹起性小腸潰瘍に対するアガロオリゴ糖の予防効果2015
- Author(s)
  東村泰希・内藤裕二・髙木智久・谷村祐子・水島かつら・春里暁人・福居顕文・寄木浩行・半田修・大野木宏・吉川敏一
- Journal Title
  
  Vitamins (Japan)
  
  Volume: 89 Pages: 53-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] Propionate Promotes Fatty Acid Oxidation through the Up-Regulation of Peroxisome Proliferator-Activated Receptor α in Intestinal Epithelial Cells2015
- Author(s)
  Higashimura, Y., Naito Y., Takagi T., Uchiyama K., Mizushima K., and Yoshikawa T.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 61 Issue: 6 Pages: 511-515
- DOI
  10.3177/jnsv.61.511
- NAID
  130005125490
- ISSN
  0301-4800, 1881-7742
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25750050, KAKENHI-PROJECT-25460958
[Journal Article] Immune Efficacy and Safety of Fucoidan Extracted from Gagome Kombu (Kjellmaniella crassifolai) in Healthy Japanese Subjects.2015
- Author(s)
  Ohnogi H, NaitoY, Higashimura Y, Uno K, Yoshikawa T
- Journal Title
  
  Japanese Journal of Complementary and Alternative Medicine
  
  Volume: 12(2) Pages: 87-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] Heme oxygenase-1 and anti-inflammatory M2 macrophages2014
- Author(s)
  Naito, Y. Takagi, T. Higashimura, Y
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 564 Pages: 83-86
- DOI
  10.1016/j.abb.2014.09.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460958, KAKENHI-PROJECT-25460959, KAKENHI-PROJECT-25750050
[Journal Article] Beneficial effect of heat-treated Enterococcus faecalis FK-23 on high-fat diet-induced hepatic steatosis in mice.2014
- Author(s)
  Kondoh, M., Shimada, T., Fukada, K., Morita, M., Katada, K., Higashimura, Y., Mizushima, K., Okamori, M., Naito, Y., and Yoshikawa, T
- Journal Title
  
  Br. J. Nutr.
  
  Volume: 112 Issue: 6 Pages: 868-875
- DOI
  10.1017/s0007114514001792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25750050
[Journal Article] Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice2014
- Author(s)
  Higashimura, Y. Naito, Y. Takagi, T. Tanimura, Y. Mizushima, K. Harusato, A. Fukui, A. Yoriki, H. Handa, O. Ohnogi, H. Yoshikawa, T.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 2 Pages: 310-317
- DOI
  10.1111/jgh.12373
- NAID
  110009917750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460958, KAKENHI-PROJECT-25460959, KAKENHI-PROJECT-25750050
[Journal Article] MDR1 is related to intestinal epithelial injury induced by acetylsalicylic acid.2013
- Author(s)
  Kugai M, Uchiyama K, Tsuji T, Yoriki H, Fukui A, Qin Y, Higashimura Y, Mizushima K, Yoshida N, Katada K, Kamada K, Handa O, Takagi T, Konishi H, Yagi N, Yoshikawa T, Shirasaka Y, Tamai I, Naito Y, and Itoh Y.
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 32 Issue: 4 Pages: 942-950
- DOI
  10.1159/000354497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175, KAKENHI-PROJECT-25750050
[Presentation] 転写抑制因子Bach1は多量体免疫グロブリン受容体の発現調節を介して腸管腔へのIgA分泌を制御する2024
- Author(s)
  東村泰希1、松本健司、三谷塁一、髙木智久、武藤哲彦、五十嵐和彦、内藤裕二
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 亜鉛欠乏から見る炎症性腸疾患の発症・進展の分子機序2023
- Author(s)
  東村泰希
- Organizer
  メタルバイオサイエンス研究会2023
- Invited
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 腸管管腔内へのIgA分泌における転写抑制因子Bach1の関与2023
- Author(s)
  東村泰希、水島かつら、髙木智久、武藤哲彦、五十嵐和彦、内藤裕二
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] マウスを用いたトランス脂肪酸の炎症性腸疾患への影響の解析2022
- Author(s)
  東村泰希
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] Oligosaccharides from agar extends lifespan through the activations of unfolded protein response and IIS pathway in Caenorhabditis elegans2022
- Author(s)
  Natsumi Desaka, Hitomi Nishikawa,Katsura Mizushima, Tomohisa Takagi, Yuji Naito, Yasuki Higashimura
- Organizer
  22nd International Union of Nutritional Sciences International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 大腸ゴブレット細胞の機能における転写抑制因子 Bach1 の影響について2022
- Author(s)
  米澤明莉, 水島かつら, 平井泰子, 舘野浩章, 武藤哲彦,五十嵐和彦, 髙木智久, 内藤裕二, 東村泰希
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] IgAを介した腸管粘膜免疫における転写抑制因子Bach1の役割について2022
- Author(s)
  濵田理久、水島かつら、髙木智久、武藤哲彦、五十嵐和彦、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] Aggravation of intestinal inflammation mediated by zinc deficiency2022
- Author(s)
  東村泰希
- Organizer
  第76回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 大腸ムチンの量的・質的変化における転写抑制因子Bach1 の影響2022
- Author(s)
  米澤明莉、水島かつら、平井泰子、舘野浩章、武藤哲彦、五十嵐和彦、髙木智久、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] Involvement of transcription repressor Bach1 in function of intestinal goblet cells2022
- Author(s)
  Akari Yonezawa, Katsura Mizushima, Yasuko Hirai, Hiroaki Tateno, Akihiko Muto, Kazuhiko Igarashi, Tomohisa Takagi, Yuji Naito, Yasuki Higashimura
- Organizer
  22nd International Union of Nutritional Sciences International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 転写抑制因子Bach1は多量体免疫グロブリン受容体の発現調節を介して腸管腔へのIgA分泌を制御する2022
- Author(s)
  東村泰希，水島かつら，髙木智久，武藤哲彦，五十嵐和彦，内藤裕二
- Organizer
  第75回日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 寒天由来のオリゴ糖：アガロオリゴ糖の健康機能性について2022
- Author(s)
  東村泰希
- Organizer
  日本農芸化学会関西支部第516 回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 転写抑制因子Bach1が腸管粘膜免疫でのIgA分泌に及ぼす影響2021
- Author(s)
  濵田理久、水島かつら、髙木智久、武藤哲彦、五十嵐和彦、内藤裕二、東村泰希
- Organizer
  第79回日本栄養・食糧学会中部支部大会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 腸管粘膜でのIgA分泌における転写抑制因子Bach1の機能解析2021
- Author(s)
  濵田理久、髙木智久、水島かつら、武藤哲彦、五十嵐和彦、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 大腸ムチンの糖鎖構造組成に及ぼす転写抑制因子 Bach1の影響2021
- Author(s)
  米澤明莉、水島かつら、平井泰子、舘野浩章、武藤哲彦、五十嵐和彦、高木智久、内藤裕二、東村泰希
- Organizer
  第72回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K05471
[Presentation] 転写抑制因子Bach1の欠損は大腸上皮において細胞増殖を促進する2021
- Author(s)
  谷川潤、水島かつら、平井泰子、武藤哲彦、五十嵐和彦、髙木智久、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 転写抑制因子Bach1の欠損に伴う大腸ムチンの性状変化について2021
- Author(s)
  米澤明莉、谷川潤、水島かつら、平井泰子、武藤哲彦、五十嵐和彦、髙木智久、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] アガロオリゴ糖はsir-2.1を介してCaenorhabditis elegansの寿命を延伸する2021
- Author(s)
  出坂夏美、西川仁美、水島かつら、髙木智久、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 転写抑制因子Bach1は大腸粘液分泌に関与する2020
- Author(s)
  谷川潤、髙木智久、水島かつら、平井泰子、武藤哲彦、五十嵐和彦、内藤裕二、東村泰希
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] Caenorhabditis elegansを用いたStreptococcus thermophilusの寿命延伸効果の検証2020
- Author(s)
  東村泰希、大田千夏、出坂夏美、西川仁美、内藤裕二
- Organizer
  第20回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] アガロオリゴ糖はCaenorhabditis elegansの寿命を延伸させる2020
- Author(s)
  出坂夏美、西川仁美、水島かつら、髙木智久、内藤裕二、東村泰希
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] Oligosaccharides from agar extends the lifespan of Caenorhabditis elegans2019
- Author(s)
  Natsumi Desaka, Hitomi Nishikawa, Katsura Mizushima, Tomohisa Takagi, Yuji Naito, Yasuki Higashimura
- Organizer
  7th International Conference on Food Factors
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] Involvement of transcription repressor Bach1 in colonic mucous secretion in mice2019
- Author(s)
  Jun Tanikawa, Yasuki Higashimura, Tomohisa Takagi, Katsura Mizushima, Yasuko Hirai, Akihiko Muto, Kazuhiko Igarashi, Yuji Naito
- Organizer
  9th biennial meeting for the Society for Free Radical Research Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 転写抑制因子Bach1欠損に伴う大腸粘液分泌亢進における機序解析2019
- Author(s)
  東村泰希，谷川潤，髙木智久，水島かつら，武藤哲彦，五十嵐和彦，内藤裕二
- Organizer
  第72回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] Influence of oligosaccharides from agar on longevity of Caenorhabditis elegans2019
- Author(s)
  Yasuki Higashimura
- Organizer
  9th biennial meeting for the Society for Free Radical Research Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 抗酸化経路制御に基づく大腸疾患予防に関する食品機能学的研究2018
- Author(s)
  東村泰希
- Organizer
  第74回日本栄養・食糧学会中部支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 亜鉛欠乏と腸管炎症2018
- Author(s)
  東村泰希
- Organizer
  第16回亜鉛栄養治療研究会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K16281
[Presentation] マウスの腸内環境における分子状水素溶存アルカリ性電解水の影響2018
- Author(s)
  東村泰希
- Organizer
  日本機能水学会第17回学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] Beneficial functions of oligosaccharides from agar2018
- Author(s)
  Yasuki Higashimura
- Organizer
  Gut Health Congress Asia 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 大腸粘液分泌機構における転写抑制因子Bach1の機能解析2018
- Author(s)
  東村泰希、柳沼明日香、髙木智久、水島かつら、武藤哲彦、五十嵐和彦、内藤裕二
- Organizer
  第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-18K05475
[Presentation] 栄養・食品成分による腸管免疫細胞の機能制御を基軸とした大腸炎予防2017
- Author(s)
  東村泰希
- Organizer
  カロテノイド研究会若手の会
- Invited
- Data Source
  KAKENHI-PROJECT-16K16281
[Presentation] 亜鉛欠乏に伴う腸管炎症の増悪について2017
- Author(s)
  東村泰希，内藤裕二
- Organizer
  第28回日本微量元素学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K16281
[Presentation] 亜鉛欠乏に伴うIL17A産生亢進における分子機序の解明2016
- Author(s)
  東村泰希、内藤裕二、髙木智久、水島かつら、吉川敏一
- Organizer
  日本ビタミン学会第68回大会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K16281
[Presentation] Participation of IRF5 in the up-regulation of IL-17A production mediated by zinc deficiency2016
- Author(s)
  東村泰希，内藤裕二，髙木智久，水島かつら，吉川敏一
- Organizer
  第27回日本微量元素学会学術集会
- Place of Presentation
  芝蘭会館（京都府京都市）
- Year and Date
  2016-07-30
- Data Source
  KAKENHI-PROJECT-16K16281
[Presentation] 亜鉛欠乏に伴う腸管炎症増悪における分子機序の解明2016
- Author(s)
  東村泰希
- Organizer
  第9回北陸合同バイオシンポジウム
- Place of Presentation
  グランディア芳泉（福井県あわら市）
- Year and Date
  2016-11-04
- Invited
- Data Source
  KAKENHI-PROJECT-16K16281
[Presentation] 亜鉛はマクロファージの形質分化制御を介して腸管炎症を抑制する2015
- Author(s)
  東村泰希、内藤裕二、髙木智久、水島かつら、吉川敏一
- Organizer
  日本ビタミン学会第67回大会
- Place of Presentation
  奈良
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 腸内環境の異常“Gut dysbiosis”に対するAgaphytoseの有効性2015
- Author(s)
  東村泰希
- Organizer
  第2回腸内細菌をターゲットとした食品開発研究会
- Place of Presentation
  大阪
- Year and Date
  2015-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] Agaro-oligosaccharides prevent high-fat diet-induced gut dysbiosis in mice with regard to the correlation between gut microbiota and bile acid profile2015
- Author(s)
  Yasuki Higashimura, Yuji Naito, Tomohisa Takagi, Katsura Mizushima, Hiromu Ohnogi, Yoko Kudo, Madoka Yasui, Seina Inui, Jun Mochiduki, Akira Honda, Yasushi Matsuzaki, Toshikazu Yoshikawa
- Organizer
  6th International Conference on Food Factors (ICoFF2015)
- Place of Presentation
  Seoul
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] Zinc deficiency aggravates intestinal inflammation through the regulation of macrophage polarization2015
- Author(s)
  Yasuki Higashimura, Yuji Naito, Tomohisa Takagi, Katsura Mizushima, Toshikazu Yoshikawa
- Organizer
  12th Asian Congress of Nutrition
- Place of Presentation
  yokohama
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 亜鉛シグナルを介した酸化型／還元型マクロファージの形質分化制御は腸管炎症の増悪に寄与する2015
- Author(s)
  東村泰希、内藤裕二、髙木智久、水島かつら、吉川敏一
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] Protective effect of agaro-oligosaccharides on high-fat diet-induced intestinal dysbiosis in mice: correlation between microbiota and bile acid profile2015
- Author(s)
  Yasuki Higashimura, Yuji Naito, Tomohisa Takagi, Katsura Mizushima Hiromu Ohnogi, Yoko Kudo, Madoka Yasui, Seina Inui, Jun Mochiduki, Akira Honda, Yasushi Matsuzaki, Toshikazu Yoshikawa
- Organizer
  Metabolomics2015
- Place of Presentation
  SAN FRANCISCO
- Year and Date
  2015-06-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] Zinc sulfate ameliorates murine intestinal inflammation through the induction of metallothionein-1 expression2014
- Author(s)
  Yasuki Higashimura, Yuji Naito, Tomohisa Takagi, Toshifumi Tsuji, Katsura Mizushima, Toshikazu Yoshikawa
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 内在性硫化水素はマクロファージの機能調節を介して腸管炎症を抑制する2014
- Author(s)
  東村泰希、内藤裕二、高木智久、平田育大、水島かつら、吉川敏一
- Organizer
  第10回HO研究フォーラム
- Place of Presentation
  京都
- Year and Date
  2014-08-29
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] Oligosaccharides from agar ameliorate intestinal inflammation through the induction of heme oxygenase-1 expression in macrophages2014
- Author(s)
  Yasuki Higashimura, Yuji Naito, Tomohisa Takagi, Katsura Mizushima, Hiromu Ohnogi, Toshikazu Yoshikawa
- Organizer
  The 32nd Annual Meeting of the Japanese Society for Cytoprotection & Cytobiology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 非ステロイド性抗炎症薬惹起性の小腸潰瘍におけるアガロオリゴ糖の予防効果2013
- Author(s)
  東村泰希、内藤裕二、高木智久、水島かつら、谷村祐子、大野木宏、吉川敏一
- Organizer
  第６６回日本酸化ストレス学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 硫化水素による腸管炎症制御の可能性2013
- Author(s)
  東村泰希、内藤裕二、高木智久、平田育大、水島かつら、吉川敏一
- Organizer
  第９回HO研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] ヘムオキシゲナーゼ-1の発現誘導を介したアガロオリゴ糖の腸管炎症抑制作用2013
- Author(s)
  大野木宏、内藤裕二、高木智久、東村泰希、水島かつら、吉川敏一
- Organizer
  第９回HO研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] Intestinal inflammation and heme oxygenase-1: role of zinc and macrophages2013
- Author(s)
  Yuji Naito, Tomohisa Takagi, Yasuki Higashimura
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] HO-1高発現M2マクロファージを標的分子にしたIBD治療2013
- Author(s)
  内藤裕二、高木智久、内山和彦、堅田和弘、東村泰希
- Organizer
  第50回日本消化器免疫学会総会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] マクロファージの機能調節に起因する硫化水素の腸管炎症抑制作用
- Author(s)
  東村泰希、内藤裕二、高木智久、平田育大、水島かつら、吉川敏一
- Organizer
  第１４回日本NO学会学術集会
- Place of Presentation
  佐賀
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] ラット抗がん剤誘発脱毛モデルにおけるガゴメ昆布由来フコイダンの保護作用
- Author(s)
  東村泰希、内藤裕二、大野木宏、工藤庸子、安井まどか、乾星菜、吉川敏一
- Organizer
  第１７回日本補完代替医療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] アガロオリゴ糖は腸管バリア機能の調節を介して腸管炎症を抑制する
- Author(s)
  東村泰希、内藤裕二、高木智久、水島かつら、大野木宏、工藤庸子、安井まどか、乾星菜、吉川敏一
- Organizer
  第１２回日本機能性食品医用学会総会
- Place of Presentation
  京都
- Year and Date
  2014-12-13 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] ENDOGENOUS HYDROGEN SULFIDE SUPPRESSES INTESTINAL INFLAMMATION THROUGH THE REGULATION OF MACROPHAGE POLARIZATION
- Author(s)
  Yasuki Higashimura, Yuji Naito, Tomohisa Takagi, Ikuhiro Hirata, Katsura Mizushima, Toshikazu Yoshikawa
- Organizer
  Third International Conference on Hydrogen Sulfide in Biology and Medicine
- Place of Presentation
  Kyoto
- Year and Date
  2014-06-04 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 亜鉛の腸管炎症制御機構におけるマクロファージの関与
- Author(s)
  東村泰希、内藤裕二、高木智久、水島かつら、吉川敏一
- Organizer
  第５１回日本消化器免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 硫酸亜鉛による炎症性腸疾患治療の可能性
- Author(s)
  東村泰希、内藤裕二、高木智久、水島かつら、吉川敏一
- Organizer
  第４２回日本潰瘍学会
- Place of Presentation
  東京
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-25750050
[Presentation] 硫酸亜鉛はmetallothionein-1の発現誘導を介して腸管炎症を抑制する
- Author(s)
  東村泰希、内藤裕二、高木智久、辻俊史、水島かつら、吉川敏一
- Organizer
  第６７回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25750050

1. Naito Yuji (00305575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 内山和彦 (50298428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 吉田直久 (50340089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 高木智久 (70405257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. 半田修 (90381970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HONDA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. SHIRASAKA Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 伊藤友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 堅田和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 関口光広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山地亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 玉井郁巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Higashimura Yasuki 東村 泰希

Research Projects

Research Products

Co-Researchers

大腸がん予防を目的としたO型糖鎖異常に関する分子機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of the transcriptional repressor Bach1 in the maintenance of colonic mucusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of transcription repressor Bach1 in colonic mucous secretionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Precision Medicine for Colon Cancer by High-throughput Analysis by Quantitative Mass Spectrometry

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel zinc-responsive protein and clarification of significance in colorectal cancer preventionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation a novel molecular mechanism of protecting colon cancer by the foo-derived componentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Heme Oxygenase-1 Induction Inhibits Intestinal Inflammation. in "Clinical Aspects of Functional Foods and Neutraceuticals"2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Prebiotic effect of galacto- <i>N</i> -biose on the intestinal lactic acid bacteria as enhancer of acetate production and hypothetical colonization2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] D-alanine Inhibits Murine Intestinal Inflammation by Suppressing IL-12 and IL-23 Production in Macrophages2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activity difference of three labdane diterpenoids on human constitutive androstane receptor2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Water‐soluble dietary fiber alleviates cancer‐induced muscle wasting through changes in gut microenvironment in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>Streptococcus thermophilus</i> extends lifespan through activation of DAF-16-mediated antioxidant pathway in <i>Caenorhabditis elegans</i>2022

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Lycopene intake induces colonic regulatory T cells in mice and suppresses food allergy symptoms.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oligosaccharides from agar extends lifespan through activation of unfolded protein response via SIR-2.1 in Caenorhabditis elegans2022

Author(s)

Higashimura Yasuki 東村泰希