Tasaki Takafumi 田崎隆史

… Alternative Names

TASAKI Takafumi 田崎隆史

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Researcher Number	70629815
Other IDs
Affiliation (Current)	2025: 金沢医科大学, 総合医学研究所, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 金沢医科大学, 総合医学研究所, 准教授 2013 – 2015: 金沢医科大学, 総合医学研究所, 准教授
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Tumor biology Except Principal Investigator Hygiene and public health
Keywords	Principal Investigator UBR4 / ユビキチンリガーゼ / 大腸炎関連大腸がんモデル / N-end rule pathway / Colon cancer / Colitis / Proteolysis / Ag/N-degron pathway / マウスモデル / 大腸がん … More / 組織特異的ノックアウトマウス / 病態モデル / ユビキチンリガーぜ / 翻訳後修飾 / DSS誘導大腸炎モデル / 腸管上皮特異的ノックアウトマウス / 網羅的遺伝子発現解析 / DSS/AOM大腸炎関連大腸がんモデル / cancer / HPV16E7 / Protein regulation / Ubiquitin / UBR box protein / UBR box / HPVE7 / 子宮頸がん / がん化 / HPV16 E7 / UBR box domain / 代謝的安定性 / E7 / がん / パピローマウイルス … More Except Principal Investigator 児童 / 疫学 / 分子生物学 / 学童 / ベトナム / 唾液中RNA / 思春期 / 睡眠 / 性差 / 発達障害 / 頬粘膜細胞 / 体内時計 / 周産期曝露 / 学習障害 / ADHD / 攻撃性 / 睡眠時間 / クロックジーン / ダイオキシン Less

大腸炎関連発癌に関与するユビキチンリガーゼUBR4の生理学的機能とその分子機構Principal Investigator
- Principal Investigator
  
  田崎隆史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kanazawa Medical University
Studies on the tissue-specific role of the ubiquitin ligase UBR4 and its basic mechanismsPrincipal Investigator
- Principal Investigator
  
  TASAKI Takafumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kanazawa Medical University
A molecular epidemiological study of associations between autism spectrum disorders induced by prenatal dioxin exposure and alteration of clock gene expressions
- Principal Investigator
  
  NISHIJO Muneko
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kanazawa Medical University
The role of UBR4/HPV16 E7 interaction in cancerPrincipal Investigator
- Principal Investigator
  
  TASAKI Takafumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa Medical University

All 2023 2022 2021 2020 2019 2018 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] UBR4/POE facilitates secretory trafficking to maintain circadian clock synchrony2022
- Author(s)
  Hegazi Sara、Cheng Arthur H.、Krupp Joshua J.、Tasaki Takafumi、Liu Jiashu、Szulc Daniel A.、Ling Harrod H.、Rios Garcia Julian、Seecharran Shavanie、Basiri Tayebeh、Amiri Mehdi、Anwar Zobia、Ahmad Safa、Nayal Kamar、Sonenberg Nahum、Liu Bao-Hua、Cheng Hai-Ling Margaret、Levine Joel D.、Cheng Hai-Ying Mary
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1594-1594
- DOI
  10.1038/s41467-022-29244-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06119, KAKENHI-PROJECT-21K06088
[Journal Article] The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome2018
- Author(s)
  Kim Sung Tae、Lee Yoon Jee、Tasaki Takafumi、Mun Su Ran、Hwang Joonsung、Kang Min Jueng、Ganipisetti Srinivasrao、Yi Eugene C.、Kim Bo Yeon、Kwon Yong Tae
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Issue: 17
- DOI
  10.1242/jcs.217646
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06119
[Journal Article] The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins2018
- Author(s)
  Kim Sung Tae、Lee Yoon Jee、Tasaki Takafumi、Hwang Joonsung、Kang Min Jueng、Yi Eugene C.、Kim Bo Yeon、Kwon Yong Tae
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 8 Pages: e0202260-e0202260
- DOI
  10.1371/journal.pone.0202260
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06119
[Journal Article] Suppressive effect of topoisomerase inhibitors on JC polyomavirus propagation in human neuroblastoma cells.2016
- Author(s)
  Nukuzuma S, Nakamichi K, Kameoka M, Sugiura S, Nukuzuma C, Tasaki T, Takegami T.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 60 Issue: 4 Pages: 253-260
- DOI
  10.1111/1348-0421.12372
- NAID
  40020808909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430119, KAKENHI-PROJECT-26461286
[Journal Article] Replication of IMR-32-adapted JC virus clones in human embryonic kidney cells.2015
- Author(s)
  Nukuzuma S, Sugiura S, Nakamichi K, Kameoka M, Nukuzuma C, Tasaki T, Takegami T.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 59 Issue: 4 Pages: 238-242
- DOI
  10.1111/1348-0421.12243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430119
[Journal Article] TNF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014
- Author(s)
  Nukuzuma, S. Nakamichi, K. Kameoka, M. Sugiura, S. Nukuzuma, C. Tasaki, T. Takegami, T.
- Journal Title
  
  J Med Virol
  
  Volume: XX Issue: 12 Pages: 2026-2032
- DOI
  10.1002/jmv.23886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-25430119
[Journal Article] The N-end rule proteolytic system in autophagy2013
- Author(s)
  Kim ST, Tasaki T, Zakrzewska A, Yoo YD, Sa Sung K, Kim SH, Cha-Molstad H, Hwang J, Kim KA, Kim BY, Kwon YT
- Journal Title
  
  Autophagy
  
  Volume: 9 Issue: 7 Pages: 1100-1103
- DOI
  10.4161/auto.24643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430119
[Journal Article] he N-end rule and retroviral infection: no effect on integrase2013
- Author(s)
  Boso G, Tasaki T, Kwon YT, Somia NV
- Journal Title
  
  Virol J
  
  Volume: 13 Issue: 1 Pages: 233-233
- DOI
  10.1186/1743-422x-10-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430119
[Journal Article] UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy2013
- Author(s)
  Tasaki T, Kim ST, Zakrzewska A, Lee BE, Kang MJ, Yoo YD, Cha-Molstad HJ, Hwang J, Soung NK, Sung KS, Kim SH, Nguyen MD, Sun M, Yi EC, Kim BY, Kwon YT
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 110 Issue: 10 Pages: 3800-3805
- DOI
  10.1073/pnas.1217358110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430119
[Presentation] ユビキチンリガーゼUBR4欠損マウスはAOM/DSS誘導大腸がんを誘発する2023
- Author(s)
  田崎隆史、佐々木隼人、佐々木宣哉
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K06088
[Presentation] 大腸炎関連大腸がんモデルにおけるユビキチンリガーゼUBR4の役割2022
- Author(s)
  田崎隆史, 佐々木隼人, 佐々木宣哉
- Organizer
  第69回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K06088
[Presentation] UBR4-HPV16E7相互作用の分子機構2021
- Author(s)
  田崎　隆史, 佐々木　隼人, 佐々木　宣哉
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06119
[Presentation] UBR4-HPV16E7相互作用の分子機構2021
- Author(s)
  田崎　隆史, 佐々木　隼人, 佐々木　宣哉
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06088
[Presentation] DSS誘導大腸炎モデルにおけるユビキチンリガーゼUBR4の役割2020
- Author(s)
  田崎隆史、佐々木隼人、佐々木宣哉
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K06119
[Presentation] The role of N-recognin UBR4 in endosomal-lysosomal system2019
- Author(s)
  Yoon Jee Lee, Sung Tae Kim, Joonsung Hwang, Takafumi Tasaki, Bo Yeon Kim, and Yong Tae Kwon
- Organizer
  1st Anuual meeting of the International Society of Protein Termini, Protein Termini 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06119
[Presentation] 腸管上皮細胞特異的UBR4ノックアウトマウスはAOM/DSS誘導大腸炎を悪化させる2019
- Author(s)
  田崎隆史, 佐々木隼人, 佐々木宣哉
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06119
[Presentation] D-ribose誘導体EdAPによる日本脳炎ウイルス複製阻害2015
- Author(s)
  田崎　隆史、北川　陽子、大類　洋、菅原二三男、竹上　勉
- Organizer
  第50回日本脳炎ウイルス生態学研究会
- Place of Presentation
  ホテル京都エミナース（京都府京都市）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25430119
[Presentation] UBR4-E7相互作用はUBR box領域を介している2015
- Author(s)
  田崎隆史
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25430119
[Presentation] デオキシヌクレオチド類似体EdAPによる抗日本脳炎ウイルス作用2015
- Author(s)
  田崎　隆史、北川　陽子、大類　洋、菅原二三男、奴久妻聡一、竹上　勉
- Organizer
  第63回日本ウイルス学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25430119
[Presentation] UBR-box protein UBR4の分子生物学2014
- Author(s)
  田崎隆史、Yong Tae Kwon、竹上勉
- Organizer
  日本生化学会北陸支部第32回大会
- Place of Presentation
  富山大学杉谷キャンパス（富山県富山市）
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25430119
[Presentation] UBR4, and N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy2013
- Author(s)
  T.Tasaki, ST. Kim, A. Zakrzewska, YT. Kwon
- Organizer
  THE 35th NAITO CONFERENCE on The Ubiquitin-Proteasome System: From Basic Mechanisms to Phathophysiological Roles
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-25430119
[Presentation] 宿主細胞内pHによる日本脳炎ウイルス複製調節機構
- Author(s)
  田崎隆史、北川陽子、堀貴代江、奴久妻聡一、竹上勉
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（神奈川県横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25430119

1. NISHIJO Muneko (40198461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 佐々木宣哉 (20302614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 杉浦重樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tasaki Takafumi 田崎 隆史

TASAKI Takafumi 田崎 隆史

Research Projects

Research Products

Co-Researchers

大腸炎関連発癌に関与するユビキチンリガーゼUBR4の生理学的機能とその分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the tissue-specific role of the ubiquitin ligase UBR4 and its basic mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A molecular epidemiological study of associations between autism spectrum disorders induced by prenatal dioxin exposure and alteration of clock gene expressions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of UBR4/HPV16 E7 interaction in cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] UBR4/POE facilitates secretory trafficking to maintain circadian clock synchrony2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressive effect of topoisomerase inhibitors on JC polyomavirus propagation in human neuroblastoma cells.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Replication of IMR-32-adapted JC virus clones in human embryonic kidney cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TNF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The N-end rule proteolytic system in autophagy2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] he N-end rule and retroviral infection: no effect on integrase2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] ユビキチンリガーゼUBR4欠損マウスはAOM/DSS誘導大腸がんを誘発する2023

Author(s)

Organizer

Data Source

[Presentation] 大腸炎関連大腸がんモデルにおけるユビキチンリガーゼUBR4の役割2022

Tasaki Takafumi 田崎隆史

TASAKI Takafumi 田崎隆史