• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Sakai Yuji  境 祐二

Researcher Number 70631779
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2184-4304
Affiliation (Current) 2025: 横浜市立大学, 生命ナノシステム科学研究科(八景キャンパス), 特任教員
Affiliation (based on the past Project Information) *help 2022 – 2024: 京都大学, 医生物学研究所, 特定准教授
2018 – 2021: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 43040:Biophysics-related / Basic Section 43010:Molecular biology-related / Basic Section 44010:Cell biology-related
Except Principal Investigator
Basic Section 43030:Functional biochemistry-related
Keywords
Principal Investigator
ソフトマター物理 / 生物物理 / 数理生物学 / 生物物理学 / オルガネラ / 数理モデル / 染色体 / シミュレーション / 分子動力学 / 高分子物理 … More / クロマチン動態 / トポイソメラーゼ / コンデンシン / 数理生物 / イメージング / オートファジー / 膜ダイナミクス / 形態形成 / 三次元電子顕微鏡 / 膜変形 / 超解像顕微鏡 / 分子生物学 / クロマチン / 一分子計測 / 分子シミュレーション / 数理モデリング / ソフトマター / 細胞生物学 / 理論生物 / 染色体分離 / 染色体凝縮 / 分子動力学シミュレーション / 高分子物理学 / 染色体形成 / 細胞生物 / 相分離 / 形の相転移 / 膜物理 / 曲率因子 / 膜物理学 / ソフトマター物理学 / 定量生物学 / 理論生物学 / 膜リモデリング … More
Except Principal Investigator
エクソソーム / ミクロオートファジー / マクロオートファジー / LLPS / フェリチン液滴 Less
  • Research Projects

    (5 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (2 People)
  •  フェリチン液滴オートファジーの分子メカニズムの総合的理解

    • Principal Investigator
      山本 林
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Nippon Medical School
  •  Theoretical study of autophagic membrane dynamicsPrincipal Investigator

    • Principal Investigator
      境 祐二
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kyoto University
  •  Theoretical study for mitotic chromosome assemblyPrincipal Investigator

    • Principal Investigator
      Sakai Yuji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Kyoto University
      The University of Tokyo
  •  Theoretical study of autophagy dynamicsPrincipal Investigator

    • Principal Investigator
      Sakai Yuji
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      The University of Tokyo
  •  Theoretical study of chromosome shaping and segregationPrincipal Investigator

    • Principal Investigator
      境 祐二
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

  • [Book] 医学のあゆみ 272巻9号「オートファゴソーム形成の物理モデル」2020

    • Author(s)
      境祐二、本田郁子
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2024

    • Author(s)
      Sakai Yuji、Takahashi Satoru、Koyama-Honda Ikuko、Saito Chieko、Mizushima Noboru
    • Journal Title

      Nature Communications

      Volume: 15 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41467-023-44442-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05715, KAKENHI-PUBLICLY-22H04635
  • [Journal Article] A mechanism that ensures non-selective cytoplasm degradation by autophagy2023

    • Author(s)
      Kotani Tetsuya、Sakai Yuji、Kirisako Hiromi、Kakuta Chika、Kakuta Soichiro、Ohsumi Yoshinori、Nakatogawa Hitoshi
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 5815-5815

    • DOI

      10.1038/s41467-023-41525-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06123, KAKENHI-PROJECT-23K05715
  • [Journal Article] 分裂期染色体形成の数理モデル・シミュレーション2023

    • Author(s)
      境祐二
    • Journal Title

      アグリバイオ

      Volume: 7 Pages: 1159-1164

    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Journal Article] 分裂期染色体形成ダイナミクスの理論的解明2022

    • Author(s)
      境祐二
    • Journal Title

      月刊 細胞

      Volume: 54(11) Pages: 642-645

    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Journal Article] 染色体形成ダイナミクスの数理モデリング2022

    • Author(s)
      境祐二
    • Journal Title

      アグリバイオ

      Volume: 6(12) Pages: 1170-1175

    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2022

    • Author(s)
      Sakai Yuji、Takahashi Satoru、Koyama-Honda Ikuko、Saito Chieko、Mizushima Noboru
    • Journal Title

      bioRxiv

      Volume: 500884 Pages: 1-25

    • DOI

      10.1101/2022.07.20.500884

    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Journal Article] Mathematical Model of Membrane Deformation Dynamics in Autophagosome Formation2022

    • Author(s)
      SAKAI Yuji
    • Journal Title

      Seibutsu Butsuri

      Volume: 62 Issue: 1 Pages: 50-52

    • DOI

      10.2142/biophys.62.50

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06482, KAKENHI-PROJECT-23K05715
  • [Journal Article] Modeling Membrane Morphological Change during Autophagosome Formation2020

    • Author(s)
      Sakai Yuji、Koyama-Honda Ikuko、Tachikawa Masashi、Knorr Roland L.、Mizushima Noboru
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 101466-101466

    • DOI

      10.1016/j.isci.2020.101466

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06482, KAKENHI-PUBLICLY-20H04903
  • [Journal Article] Molecular dynamics simulations of condensin-mediated mitotic chromosome assembly2019

    • Author(s)
      Yuji Sakai, Tatsuya Hirano, Masashi Tachikawa
    • Journal Title

      Methods in Molecular Biology

      Volume: 2004 Pages: 319-334

    • DOI

      10.1007/978-1-4939-9520-2_22

    • ISBN
      9781493995196, 9781493995202
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04708, KAKENHI-PLANNED-15H05971, KAKENHI-PROJECT-18H05276
  • [Journal Article] Modeling the functions of condensin in chromosome shaping and segregation2018

    • Author(s)
      Sakai Yuji、Mochizuki Atsushi、Kinoshita Kazuhisa、Hirano Tatsuya、Tachikawa Masashi
    • Journal Title

      PLOS Computational Biology

      Volume: 14 Issue: 6 Pages: e1006152-e1006152

    • DOI

      10.1371/journal.pcbi.1006152

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04708, KAKENHI-PUBLICLY-18H04768, KAKENHI-PUBLICLY-18H04874, KAKENHI-PROJECT-15K06959
  • [Presentation] Molecular dynamics of autophagosomal lipid transfer Atg22023

    • Author(s)
      Sakai Yuji, Noda N. Nobuo, Sugita Yuji
    • Organizer
      The 34th IUPAP Conference on Computational Physics CCP 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Presentation] 未閉鎖オートファゴソームの標準形態の実験的決定と理論モデル2023

    • Author(s)
      境 祐二, 髙橋 暁 ,小山-本田 郁子, 齊藤 知恵子, 水島 昇
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Presentation] オートファゴソーム形成における脂質輸送の分子動力学2023

    • Author(s)
      境祐二, 的場一晃, 杉田有治, 野田展生
    • Organizer
      第15回オートファジー研究会
    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Presentation] Experimental determination and theoretical model of standard shapes of forming autophagosomes2023

    • Author(s)
      Sakai Yuji, Takahashi Satoru, Saito Chieko, Koyama-Honda Ikuko, Noboru Mizushima
    • Organizer
      11th International Conference on Biological Physics ICBP 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Presentation] Modeling of mitotic chromosome shaping2023

    • Author(s)
      Sakai Yuji
    • Organizer
      第75回日本細胞生物学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Presentation] Molecular dynamics of autophagosomal lipid transfer2023

    • Author(s)
      Sakai Yuji, Matoba Kazuaki, Noda N. Nobuo, Sugita Yuji
    • Organizer
      第61回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-23K05715
  • [Presentation] オートファゴソーム形成における膜変形の定量化と理論モデル2022

    • Author(s)
      境 祐二、髙橋 暁、小山-本田 郁子、齊藤 知恵子、水島 昇
    • Organizer
      第74回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] オートファゴソーム形成における膜形態変化の数理モデリング2022

    • Author(s)
      境祐二
    • Organizer
      2022年度数理生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] 分裂期におけるクロマチン動態と構造の数理モデル2022

    • Author(s)
      境祐二
    • Organizer
      ゲノムモデリング研究会
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] Experimental determination and theoretical model of standard shapes of forming autophagosomes2022

    • Author(s)
      Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] オートファゴソーム形成の膜変形ダイナミクスの数理モデル2022

    • Author(s)
      境祐二
    • Organizer
      京都大学ウイルス再生医科学研究所セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] Modeling Membrane Morphological Change during Autophagosome Formation2021

    • Author(s)
      Yuji Sakai
    • Organizer
      iTHEMS Biology Seminar
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] オートファゴソーム形成の膜物理2021

    • Author(s)
      境祐二
    • Organizer
      ERATO シンポジウム「形の細胞生物学:理論と実験で迫る」
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] オートファゴソーム形成における 隔離膜形態の標準化と数理モデル2021

    • Author(s)
      境祐二、髙橋暁、小山-本田郁子、齊藤知恵子、水島昇
    • Organizer
      オートファジー研究会
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] オートファゴソーム形成における膜動態のモデリング2020

    • Author(s)
      境祐二、本田 郁子、立川 正志、Roland Knorr、水 島 昇
    • Organizer
      第20回東京大学生命科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K06482
  • [Presentation] Theoretical modeling for autophagosome formation2019

    • Author(s)
      境祐二,本田-小山郁子, 立川正志, Roland Knorr, 水島昇
    • Organizer
      第19回東京大学生命科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Modeling autophagosome formation2019

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
    • Organizer
      Joint 12th EBSA / 10th ICBP-IUPAP Biophysics Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Modeling cooperative action of condensin and topo II in mitotic chromosome assembly2019

    • Author(s)
      Yuji Sakai
    • Organizer
      Chromosome Dynamics 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] 染色体の形と分離の関係2019

    • Author(s)
      境祐二
    • Organizer
      サイズ生物学ワークショップ
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] Theoretical modeling for autophagosome formation2019

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
    • Organizer
      China-Japan-Korea Symposium on Autophagy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] オートファゴソーム形成の理論モデル2019

    • Author(s)
      境祐二,本田-小山郁子, 立川正志, Roland Knorr, 水島昇
    • Organizer
      第12回オートファジー研究会
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Modeling cooperative action of condensin and topo II in mitotic chromosome assembly2019

    • Author(s)
      Y. Sakai, M. Tachikawa, K. Kinoshita, T. Hirano
    • Organizer
      EMBO Workshop: Organization of bacterial and eukaryotic genomes by SMC complexes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] Modeling of condensin functions in chromosome shaping and segregation2019

    • Author(s)
      境祐二
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] コンデンシンと Ki-67 による凝縮染色体形成の数理モデル2019

    • Author(s)
      境祐二
    • Organizer
      第36回染色体ワークショップ/第17回核ダイナミクス研究会
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] Theoretical modeling for autophagosome formation2019

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
    • Organizer
      EMBO Workshop: Membrane shaping and remodeling by proteins
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Modeling and simulation of condensin and Ki-67 on mitotic chromosome assembly2019

    • Author(s)
      Yuji Sakai
    • Organizer
      The 8th Meeting on Chromosome Orchestration System
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] Modeling morphological change during autophagosome formation2019

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
    • Organizer
      EMBO Workshop: Autophagy: From molecular principles to human diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Mathematical modelling for autophagosome formation2018

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Noboru Mizushima
    • Organizer
      2018 Annual Meeting of the Society for Mathematical Biology & the Japanese Society for Mathematical Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Physical modeling for autophagosome formation2018

    • Author(s)
      境祐二
    • Organizer
      細胞システムの動態と論理X
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Physical Modeling for autophagosome formation2018

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Noboru Mizushima
    • Organizer
      Physics of living matter
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] Modeling and Simulation of condensin functions on chromosome shaping and segregation2018

    • Author(s)
      Yuji Sakai, Atsushi Mochizuki, Kazuhisa Kinoshita, Tatsuya Hirano, Masashi Tachikawa
    • Organizer
      Principles of Chromosome Structure and Function
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] Modeling of condensin functions on chromosome shaping and segregation2018

    • Author(s)
      Yuji Sakai
    • Organizer
      The 7th Meeting on Chromosome Orchestration System
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • [Presentation] Model of autophagosome formation regulated by curvature-generators2018

    • Author(s)
      Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Noboru Mizushima
    • Organizer
      Advances in Physics of Emergent orders in Fluctuations 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14693
  • [Presentation] コンデンシンによる分裂期染色体形成の物理モデル2018

    • Author(s)
      境祐二
    • Organizer
      クロマチン・細胞核の動的構造変換とゲノム機能制御
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04708
  • 1.  山本 林 (80551283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  小谷 哲也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi