Sakai Yuji 境祐二

Researcher Number	70631779
Other IDs	https://orcid.org/0000-0002-2184-4304
Affiliation (Current)	2025: 横浜市立大学, 生命ナノシステム科学研究科(八景キャンパス), 特任教員
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都大学, 医生物学研究所, 特定准教授 2018 – 2021: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Basic Section 43010:Molecular biology-related / Basic Section 44010:Cell biology-related Except Principal Investigator Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator ソフトマター物理 / 生物物理 / 数理生物学 / 生物物理学 / オルガネラ / 数理モデル / 染色体 / シミュレーション / 分子動力学 / 高分子物理 … More / クロマチン動態 / トポイソメラーゼ / コンデンシン / 数理生物 / イメージング / オートファジー / 膜ダイナミクス / 形態形成 / 三次元電子顕微鏡 / 膜変形 / 超解像顕微鏡 / 分子生物学 / クロマチン / 一分子計測 / 分子シミュレーション / 数理モデリング / ソフトマター / 細胞生物学 / 理論生物 / 染色体分離 / 染色体凝縮 / 分子動力学シミュレーション / 高分子物理学 / 染色体形成 / 細胞生物 / 相分離 / 形の相転移 / 膜物理 / 曲率因子 / 膜物理学 / ソフトマター物理学 / 定量生物学 / 理論生物学 / 膜リモデリング … More Except Principal Investigator エクソソーム / ミクロオートファジー / マクロオートファジー / LLPS / フェリチン液滴 Less

フェリチン液滴オートファジーの分子メカニズムの総合的理解
- Principal Investigator
  
  山本林
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nippon Medical School
Theoretical study of autophagic membrane dynamicsPrincipal Investigator
- Principal Investigator
  
  境祐二
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Theoretical study for mitotic chromosome assemblyPrincipal Investigator
- Principal Investigator
  
  Sakai Yuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyoto University
  The University of Tokyo
Theoretical study of autophagy dynamicsPrincipal Investigator
- Principal Investigator
  
  Sakai Yuji
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokyo
Theoretical study of chromosome shaping and segregationPrincipal Investigator
- Principal Investigator
  
  境祐二
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 医学のあゆみ 272巻9号「オートファゴソーム形成の物理モデル」2020
- Author(s)
  境祐二、本田郁子
- Total Pages
  5
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20K06482
[Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2024
- Author(s)
  Sakai Yuji、Takahashi Satoru、Koyama-Honda Ikuko、Saito Chieko、Mizushima Noboru
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41467-023-44442-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05715, KAKENHI-PUBLICLY-22H04635
[Journal Article] A mechanism that ensures non-selective cytoplasm degradation by autophagy2023
- Author(s)
  Kotani Tetsuya、Sakai Yuji、Kirisako Hiromi、Kakuta Chika、Kakuta Soichiro、Ohsumi Yoshinori、Nakatogawa Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 5815-5815
- DOI
  10.1038/s41467-023-41525-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06123, KAKENHI-PROJECT-23K05715
[Journal Article] 分裂期染色体形成の数理モデル・シミュレーション2023
- Author(s)
  境祐二
- Journal Title
  
  アグリバイオ
  
  Volume: 7 Pages: 1159-1164
- Data Source
  KAKENHI-PROJECT-23K05715
[Journal Article] 分裂期染色体形成ダイナミクスの理論的解明2022
- Author(s)
  境祐二
- Journal Title
  
  月刊　細胞
  
  Volume: 54(11) Pages: 642-645
- Data Source
  KAKENHI-PROJECT-20K06482
[Journal Article] 染色体形成ダイナミクスの数理モデリング2022
- Author(s)
  境祐二
- Journal Title
  
  アグリバイオ
  
  Volume: 6(12) Pages: 1170-1175
- Data Source
  KAKENHI-PROJECT-20K06482
[Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2022
- Author(s)
  Sakai Yuji、Takahashi Satoru、Koyama-Honda Ikuko、Saito Chieko、Mizushima Noboru
- Journal Title
  
  bioRxiv
  
  Volume: 500884 Pages: 1-25
- DOI
  10.1101/2022.07.20.500884
- Data Source
  KAKENHI-PROJECT-20K06482
[Journal Article] Mathematical Model of Membrane Deformation Dynamics in Autophagosome Formation2022
- Author(s)
  SAKAI Yuji
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 62 Issue: 1 Pages: 50-52
- DOI
  10.2142/biophys.62.50
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06482, KAKENHI-PROJECT-23K05715
[Journal Article] Modeling Membrane Morphological Change during Autophagosome Formation2020
- Author(s)
  Sakai Yuji、Koyama-Honda Ikuko、Tachikawa Masashi、Knorr Roland L.、Mizushima Noboru
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 9 Pages: 101466-101466
- DOI
  10.1016/j.isci.2020.101466
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06482, KAKENHI-PUBLICLY-20H04903
[Journal Article] Molecular dynamics simulations of condensin-mediated mitotic chromosome assembly2019
- Author(s)
  Yuji Sakai, Tatsuya Hirano, Masashi Tachikawa
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2004 Pages: 319-334
- DOI
  10.1007/978-1-4939-9520-2_22
- ISBN
  9781493995196, 9781493995202
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04708, KAKENHI-PLANNED-15H05971, KAKENHI-PROJECT-18H05276
[Journal Article] Modeling the functions of condensin in chromosome shaping and segregation2018
- Author(s)
  Sakai Yuji、Mochizuki Atsushi、Kinoshita Kazuhisa、Hirano Tatsuya、Tachikawa Masashi
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 14 Issue: 6 Pages: e1006152-e1006152
- DOI
  10.1371/journal.pcbi.1006152
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04708, KAKENHI-PUBLICLY-18H04768, KAKENHI-PUBLICLY-18H04874, KAKENHI-PROJECT-15K06959
[Presentation] Molecular dynamics of autophagosomal lipid transfer Atg22023
- Author(s)
  Sakai Yuji, Noda N. Nobuo, Sugita Yuji
- Organizer
  The 34th IUPAP Conference on Computational Physics CCP 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05715
[Presentation] 未閉鎖オートファゴソームの標準形態の実験的決定と理論モデル2023
- Author(s)
  境祐二, 髙橋暁 ,小山－本田郁子, 齊藤知恵子, 水島昇
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K05715
[Presentation] オートファゴソーム形成における脂質輸送の分子動力学2023
- Author(s)
  境祐二, 的場一晃, 杉田有治, 野田展生
- Organizer
  第15回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-23K05715
[Presentation] Experimental determination and theoretical model of standard shapes of forming autophagosomes2023
- Author(s)
  Sakai Yuji, Takahashi Satoru, Saito Chieko, Koyama-Honda Ikuko, Noboru Mizushima
- Organizer
  11th International Conference on Biological Physics ICBP 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05715
[Presentation] Modeling of mitotic chromosome shaping2023
- Author(s)
  Sakai Yuji
- Organizer
  第75回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K05715
[Presentation] Molecular dynamics of autophagosomal lipid transfer2023
- Author(s)
  Sakai Yuji, Matoba Kazuaki, Noda N. Nobuo, Sugita Yuji
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K05715
[Presentation] オートファゴソーム形成における膜変形の定量化と理論モデル2022
- Author(s)
  境祐二、髙橋暁、小山－本田郁子、齊藤知恵子、水島昇
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] オートファゴソーム形成における膜形態変化の数理モデリング2022
- Author(s)
  境祐二
- Organizer
  2022年度数理生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] 分裂期におけるクロマチン動態と構造の数理モデル2022
- Author(s)
  境祐二
- Organizer
  ゲノムモデリング研究会
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] Experimental determination and theoretical model of standard shapes of forming autophagosomes2022
- Author(s)
  Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] オートファゴソーム形成の膜変形ダイナミクスの数理モデル2022
- Author(s)
  境祐二
- Organizer
  京都大学ウイルス再生医科学研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] Modeling Membrane Morphological Change during Autophagosome Formation2021
- Author(s)
  Yuji Sakai
- Organizer
  iTHEMS Biology Seminar
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] オートファゴソーム形成の膜物理2021
- Author(s)
  境祐二
- Organizer
  ERATO シンポジウム「形の細胞生物学：理論と実験で迫る」
- Invited
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] オートファゴソーム形成における隔離膜形態の標準化と数理モデル2021
- Author(s)
  境祐二、髙橋暁、小山-本田郁子、齊藤知恵子、水島昇
- Organizer
  オートファジー研究会
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] オートファゴソーム形成における膜動態のモデリング2020
- Author(s)
  境祐二、本田郁子、立川正志、Roland Knorr、水島昇
- Organizer
  第20回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20K06482
[Presentation] Theoretical modeling for autophagosome formation2019
- Author(s)
  境祐二,本田-小山郁子, 立川正志, Roland Knorr, 水島昇
- Organizer
  第19回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Modeling autophagosome formation2019
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
- Organizer
  Joint 12th EBSA / 10th ICBP-IUPAP Biophysics Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Modeling cooperative action of condensin and topo II in mitotic chromosome assembly2019
- Author(s)
  Yuji Sakai
- Organizer
  Chromosome Dynamics 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] 染色体の形と分離の関係2019
- Author(s)
  境祐二
- Organizer
  サイズ生物学ワークショップ
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] Theoretical modeling for autophagosome formation2019
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
- Organizer
  China-Japan-Korea Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] オートファゴソーム形成の理論モデル2019
- Author(s)
  境祐二,本田-小山郁子, 立川正志, Roland Knorr, 水島昇
- Organizer
  第12回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Modeling cooperative action of condensin and topo II in mitotic chromosome assembly2019
- Author(s)
  Y. Sakai, M. Tachikawa, K. Kinoshita, T. Hirano
- Organizer
  EMBO Workshop: Organization of bacterial and eukaryotic genomes by SMC complexes
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] Modeling of condensin functions in chromosome shaping and segregation2019
- Author(s)
  境祐二
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] コンデンシンと Ki-67 による凝縮染色体形成の数理モデル2019
- Author(s)
  境祐二
- Organizer
  第36回染色体ワークショップ/第17回核ダイナミクス研究会
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] Theoretical modeling for autophagosome formation2019
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
- Organizer
  EMBO Workshop: Membrane shaping and remodeling by proteins
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Modeling and simulation of condensin and Ki-67 on mitotic chromosome assembly2019
- Author(s)
  Yuji Sakai
- Organizer
  The 8th Meeting on Chromosome Orchestration System
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] Modeling morphological change during autophagosome formation2019
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Roland L. Knorr, Noboru Mizushima
- Organizer
  EMBO Workshop: Autophagy: From molecular principles to human diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Mathematical modelling for autophagosome formation2018
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Noboru Mizushima
- Organizer
  2018 Annual Meeting of the Society for Mathematical Biology & the Japanese Society for Mathematical Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Physical modeling for autophagosome formation2018
- Author(s)
  境祐二
- Organizer
  細胞システムの動態と論理X
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Physical Modeling for autophagosome formation2018
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Noboru Mizushima
- Organizer
  Physics of living matter
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] Modeling and Simulation of condensin functions on chromosome shaping and segregation2018
- Author(s)
  Yuji Sakai, Atsushi Mochizuki, Kazuhisa Kinoshita, Tatsuya Hirano, Masashi Tachikawa
- Organizer
  Principles of Chromosome Structure and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] Modeling of condensin functions on chromosome shaping and segregation2018
- Author(s)
  Yuji Sakai
- Organizer
  The 7th Meeting on Chromosome Orchestration System
- Data Source
  KAKENHI-PUBLICLY-18H04708
[Presentation] Model of autophagosome formation regulated by curvature-generators2018
- Author(s)
  Yuji Sakai, Ikuko Koyama-Honda, Masashi Tachikawa, Noboru Mizushima
- Organizer
  Advances in Physics of Emergent orders in Fluctuations 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14693
[Presentation] コンデンシンによる分裂期染色体形成の物理モデル2018
- Author(s)
  境祐二
- Organizer
  クロマチン・細胞核の動的構造変換とゲノム機能制御
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04708

1. 山本林 (80551283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 小谷哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakai Yuji 境 祐二

Research Projects

Research Products

Co-Researchers

フェリチン液滴オートファジーの分子メカニズムの総合的理解

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Theoretical study of autophagic membrane dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Theoretical study for mitotic chromosome assemblyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Theoretical study of autophagy dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Theoretical study of chromosome shaping and segregationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] 医学のあゆみ 272巻9号「オートファゴソーム形成の物理モデル」2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A mechanism that ensures non-selective cytoplasm degradation by autophagy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 分裂期染色体形成の数理モデル・シミュレーション2023

Author(s)

Journal Title

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[Journal Article] 分裂期染色体形成ダイナミクスの理論的解明2022

Author(s)

Journal Title

Data Source

[Journal Article] 染色体形成ダイナミクスの数理モデリング2022

Author(s)

Journal Title

Data Source

[Journal Article] Experimental determination and mathematical modeling of standard shapes of forming autophagosomes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mathematical Model of Membrane Deformation Dynamics in Autophagosome Formation2022

Author(s)

Journal Title

DOI

ISSN

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Data Source

[Journal Article] Modeling Membrane Morphological Change during Autophagosome Formation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular dynamics simulations of condensin-mediated mitotic chromosome assembly2019

Author(s)

Journal Title

Sakai Yuji 境祐二

[Presentation] オートファゴソーム形成における隔離膜形態の標準化と数理モデル2021