Okada Ryo 岡田亮

… Alternative Names

岡田亮オカダリョウ

OKADA Ryo 岡田亮

Less

Researcher Number	70633105
Other IDs
Affiliation (Current)	2025: 産業医科大学, 産業保健学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 産業医科大学, 産業保健学部, 准教授 2015 – 2016: 産業医科大学, 医学部, 講師 2012 – 2014: 九州大学, 歯学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator Ca2+依存的不活性化機構 / ステロイド抵抗性 / 巣状分節性糸球体硬化症 / ポドサイト / P-糖タンパク質 / TRPC6 / 認知症 / ミトコンドリア電子伝達系複合体Ⅰ / 歯周病 / カテプシンB … More / ミクログリア / 体内時計 / 食細胞 / 脳炎症 / 歯周パラインフラメーション / 歯学 Less

TRPチャネル活性制御機構の破綻によるP-糖タンパク質活性亢進機序の解明Principal Investigator
- Principal Investigator
  
  岡田亮
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Regulation of periodontal disease-related cognitive impairment by controlling microglial phenotype changePrincipal Investigator
- Principal Investigator
  
  Okada Ryo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  University of Occupational and Environmental Health, Japan
  Kyushu University
Analysis of relationship between periodontal tissue para-inflammation induced neuroinflammation and phagocytic activity regulation by circadian cloclk systemPrincipal Investigator
- Principal Investigator
  
  OKADA Ryo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University

All 2023 2015 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier2015
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 64 Pages: 51-60
- DOI
  10.1016/j.mcn.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-26861555, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Phosphatidylserine recognition and induction of apoptotic cell clearance by Drosophila engulfment receptor Draper2013
- Author(s)
  Tran Thanh Tung, Kaz Nagaosa, Yu Fujita, Asana Kita, Hiroki Mori, Ryo Okada, Saori Nonaka, Yoshinobu Nakanishi
- Journal Title
  
  J. Biochem
  
  Volume: 153巻 Pages: 483-491
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Diurnal spatial rearrangement of microglial processes through the rhythmic expression of P2Y12 receptors2013
- Author(s)
  Yoshinori Hayashi, Satoru Koyanagi, Naoki Kusunose, Fumiko Takayama, Ryo Okada, Zhou Wu, Shigehiro Ohdo, Hiroshi Nakanishi
- Journal Title
  
  J. Neurol. Disord
  
  Volume: 1巻 Pages: 2-2
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin2013
- Author(s)
  S. Yoshinori Hayashi, Satoru Koyanagi, Naoki Kusunose, Ryo Okada, Zhou Wu, Hidetoshi Tozaki-Saitoh, Kiyoharu Ukai, Shinichi Kohsaka, Kazuhide Inoue, Shigehiro Ohdo, Hiroshi Nakanishi
- Journal Title
  
  Sci. Rep
  
  Volume: 3巻 Pages: 2744-2744
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S2013
- Author(s)
  Yoshinori Hayashi, Satoru Koyanagi, Naoki Kusunose, Ryo Okada, Zhou Wu, Hidetoshi Tozaki-Saitoh, Kiyoharu Ukai, Shinichi Kohsaka, Kazuhide Inoue, Hiroshi Nakanishi
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Pages: 2744-2744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kappaB activation in microglia2013
- Author(s)
  Zhou Wu, Aiqin Zhu, Fumiko Takayama, Ryo Okada, Yicong Liu, Yuka Harada, Shizheng Wu, Hiroshi Nakanishi
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2013 Pages: 906726-906726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013
- Author(s)
  Fumiko Takayama, Zhou Wu, Hong Mei Ma, Ryo Okada, Yoshinori Hayashi, Hiroshi Nakanishi
- Journal Title
  
  J. Neuroimmunol
  
  Volume: 262巻 Pages: 121-124
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013
- Author(s)
  Fumiko Takayama, Zhou Wu, Hong Mei Ma, Ryo Okada, Yoshinori Hayashi, Hiroshi Nakanishi
- Journal Title
  
  Journal of Neuroimmunology
  
  Volume: 262 Pages: 121-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Diurnal spatial reorganization of Microglial Processes through the rhythmic expression of P2Y12 receptors2013
- Author(s)
  Yoshinori Hayashi, Satoru Koyamagi, Naoki Kusunose, Fumiko Takayama, Ryo Okada, Zhou Wu, Shigehiro Ohdo, Hiroshi Nakanishi
- Journal Title
  
  Journal of Neurological Disorders
  
  Volume: 1 Pages: 121-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Differential pathways for interleukin-1βproduction activated by chromogranin A and amyloidβin microglia2013
- Author(s)
  Zhou Wu, Li Suna, Sadayuki Hashioka, Sheng Yub, Claudia Schwab, Ryo Okada, Yoshinori Hayashi, Patrick L. McGeer, Hiroshi Nakanishi
- Journal Title
  
  Neurobiol. Aging
  
  Volume: 34巻 Pages: 2715-2725
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-κB activation in microglia2013
- Author(s)
  Zhou Wu, Aiqin Zhu, Fumiko Takayama, Ryo Okada, Yicong Liu, Yuka Harada, Shizheng Wu, Hiroshi Nakanishi
- Journal Title
  
  Oxid. Med. Cell Longev
  
  Volume: 2013巻 Pages: 906726-906726
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Apoptosis-dependent externalization and involvement in apoptotic cell clearance of DmCaBP1, an endoplasmic reticulum protein of Drosophila2012
- Author(s)
  Ryo Okada, Kaz Nagaosa, Takayuki Kuraishi, Hiroshi Nakayama, Naoko Yamamoto, Yukiko Nakagawa, Naoshi Dohmae, Akiko Shiratsuchi, Yoshinobu Nakanishi
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287巻 Pages: 3138-3146
- NAID
  120003959460
- Data Source
  KAKENHI-PROJECT-24890161
[Journal Article] Integrinβν-mediated phagocytosis of apoptotic cells in Drosophila embryos2011
- Author(s)
  Kaz Nagaosa, Ryo Okada, Saori Nonaka, Kazuki Takeuchi, Yu Fujita, Tomoyuki Miyasaka, Junko Manaka, István Ando, Yoshinobu Nakanishi
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286巻 Pages: 25770-25777
- Data Source
  KAKENHI-PROJECT-24890161
[Presentation] Targeting the coiled-coil domain of TRPC6 channel with the CRISPR/Cas9 system in mouse-podocyte cell line2023
- Author(s)
  Ryo Okada，Reiko Sakaguchi，Masayuki X. Mori
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K06295
[Presentation] Ca2+依存的不活性化機構の破綻につながる変異型TRPC6を内在的に発現するポドサイト細胞株におけるTRPC6チャネル活性変化2023
- Author(s)
  岡田亮，小牧竜也，坂口怜子，木原隆典，森誠之
- Organizer
  第41回産業医科大学学会
- Data Source
  KAKENHI-PROJECT-23K06295
[Presentation] カテプシンH欠損マウスにおける実験的自己免疫性脳脊髄炎の早期発症に関する解析2014
- Author(s)
  岡田　亮、中西　博
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26861555
[Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻2013
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第18回グリア研究会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24890161
[Presentation] Batten病モデルマウスにおける脳ペリサイトの消失と血液脳関門の破綻2013
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学
- Data Source
  KAKENHI-PROJECT-24890161
[Presentation] カテプシンD欠損マウスの脳病変における脳ペリサイト消失と免疫細胞の脳内浸潤の関与2013
- Author(s)
  岡田　亮、武　洲、倪軍軍、中西　博
- Organizer
  第55回　歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24890161

1. 武洲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 林良憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 中西博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okada Ryo 岡田 亮

岡田 亮 オカダ リョウ

OKADA Ryo 岡田 亮

Research Projects

Research Products

Co-Researchers

TRPチャネル活性制御機構の破綻によるP-糖タンパク質活性亢進機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of periodontal disease-related cognitive impairment by controlling microglial phenotype changePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of relationship between periodontal tissue para-inflammation induced neuroinflammation and phagocytic activity regulation by circadian cloclk systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphatidylserine recognition and induction of apoptotic cell clearance by Drosophila engulfment receptor Draper2013

Author(s)

Journal Title

Data Source

[Journal Article] Diurnal spatial rearrangement of microglial processes through the rhythmic expression of P2Y12 receptors2013

Author(s)

Journal Title

Data Source

[Journal Article] The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin2013

Author(s)

Journal Title

Data Source

[Journal Article] The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S2013

Author(s)

Journal Title

Data Source

[Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kappaB activation in microglia2013

Author(s)

Journal Title

Data Source

[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013

Author(s)

Journal Title

Data Source

[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013

Author(s)

Journal Title

Data Source

[Journal Article] Diurnal spatial reorganization of Microglial Processes through the rhythmic expression of P2Y12 receptors2013

Author(s)

Journal Title

Data Source

[Journal Article] Differential pathways for interleukin-1βproduction activated by chromogranin A and amyloidβin microglia2013

Author(s)

Journal Title

Data Source

[Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-κB activation in microglia2013

Author(s)

Journal Title

Data Source

[Journal Article] Apoptosis-dependent externalization and involvement in apoptotic cell clearance of DmCaBP1, an endoplasmic reticulum protein of Drosophila2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Integrinβν-mediated phagocytosis of apoptotic cells in Drosophila embryos2011

Author(s)

Journal Title

Data Source

[Presentation] Targeting the coiled-coil domain of TRPC6 channel with the CRISPR/Cas9 system in mouse-podocyte cell line2023

Author(s)

Okada Ryo 岡田亮

岡田亮オカダリョウ

OKADA Ryo 岡田亮