Ishikawa Daichi 石川大地

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ISHIKAWA Daichi 石川大地

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Researcher Number	70633882
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 徳島大学専門研究員
Affiliation (based on the past Project Information) *help	2024: 徳島大学, 病院, 助教 2018 – 2019: 徳島大学, 大学院医歯薬学研究部(医学域), 徳島大学専門研究員 2016 – 2017: 徳島大学, 病院, 特任助教
Review Section/Research Field	Principal Investigator 0905:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related / General surgery
Keywords	Principal Investigator 上皮間葉転換 / 腫瘍微小環境 / CAF / 腫瘍関連線維芽細胞 / microRNA-449a / 解糖系 / 癌幹細胞 / HDAC1 / 胃癌 / 大腸癌 … More / miR-449a / EMT / 内胚葉 / microRNA / 原発性肝癌 Less

腫瘍関連線維芽細胞の脂質代謝に着目した腫瘍免疫制御のメカニズムの解明Principal Investigator
- Principal Investigator
  
  石川大地
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0905:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  The University of Tokushima
The impact of microRNA-449a on the cancer malignancy such as cancer stemness, epithelial-mesenchymal transition, and glycolysis.Principal Investigator
- Principal Investigator
  
  ISHIKAWA Daichi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The University of Tokushima
The moleculer mechanisms of epithelial to mesenchymeal transition of primary gastrointestinal tumor from the point of view of endodermal embryologyPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Daichi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General surgery
- Research Institution
  The University of Tokushima

All 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] The Role of Neutrophil-to-lymphocyte Ratio on the Effect of CRT for Patients With Rectal Cancer2020
- Author(s)
  ISHIKAWA DAICHI、NISHI MASAAKI、TAKASU CHIE、KASHIHARA HIDEYA、TOKUNAGA TAKUYA、HIGASHIJIMA JUN、YOSHIKAWA KOZO、SHIMADA MITSUO
- Journal Title
  
  In Vivo
  
  Volume: 34 Issue: 2 Pages: 863-868
- DOI
  10.21873/invivo.11850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16257, KAKENHI-PROJECT-19K09072
[Journal Article] Utility of virtual three-dimensional image analysis for laparoscopic gastrectomy conducted by trainee surgeons2019
- Author(s)
  Nishi Masaaki、Yoshikawa Kozo、Higashijima Jun、Tokunaga Takuya、Takasu Chie、Kashihara Hideya、Ishikawa Daichi、Shimada Mitsuo
- Journal Title
  
  J. Med. Invest.
  
  Volume: 66 Issue: 3.4 Pages: 280-284
- DOI
  10.2152/jmi.66.280
- NAID
  130007733039
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09072, KAKENHI-PROJECT-18K16257
[Journal Article] Expression Level of MicroRNA-449a Predicts the Prognosis of Patients With Gastric Cancer2019
- Author(s)
  ISHIKAWA DAICHI、YOSHIKAWA KOZO、TAKASU CHIE、KASHIHARA HIDEYA、NISHI MASAAKI、TOKUNAGA TAKUYA、HIGASHIJIMA JUN、SHIMADA MITSUO
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 1 Pages: 239-244
- DOI
  10.21873/anticanres.13945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16257, KAKENHI-PROJECT-19K09072
[Journal Article] The Significance of MicroRNA-449a and Its Potential Target HDAC1 in Patients With Colorectal Cancer2019
- Author(s)
  ISHIKAWA DAICHI、TAKASU CHIE、KASHIHARA HIDEYA、NISHI MASAAKI、TOKUNAGA TAKUYA、HIGASHIJIMA JUN、YOSHIKAWA KOZO、YASUTOMO KOJI、SHIMADA MITSUO
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 6 Pages: 2855-2860
- DOI
  10.21873/anticanres.13414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09072, KAKENHI-PROJECT-19K18028, KAKENHI-PROJECT-18K16257
[Journal Article] Usefulness of virtual three-dimensional image analysis in inguinal hernia as an educational tool2019
- Author(s)
  Wada Y, Nishi M, Yoshikawa K, Higashijima J, Miyatani T, Tokunaga T, Takasu C, Kashihara H, Ishikawa D, Yoshimoto T, Shimada M
- Journal Title
  
  Surg Endosc.
  
  Volume: 34(5) Issue: 5 Pages: 1923-1928
- DOI
  10.1007/s00464-019-06964-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16257, KAKENHI-PROJECT-19K09072
[Journal Article] Programmed Cell Death Ligand 1 Expression Is an Independent Prognostic Factor in Colorectal Cancer2018
- Author(s)
  ENKHBAT TUMENJIN、NISHI MASAAKI、TAKASU CHIE、YOSHIKAWA KOZO、JUN HIGASHIJIMA、TOKUNAGA TAKUYA、KASHIHARA HIDEYA、ISHIKAWA DAICHI、SHIMADA MITSUO
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 6 Pages: 3367-3373
- DOI
  10.21873/anticanres.12603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16257
[Journal Article] The Impact of Indoleamine 2,3-dioxygenase (IDO) Expression on Stage III Gastric Cancer2018
- Author(s)
  NISHI MASAAKI、YOSHIKAWA KOZO、HIGASHIJIMA JUN、TOKUNAGA TAKUYA、KASHIHARA HIDEYA、TAKASU CHIE、ISHIKAWA DAICHI、WADA YUMA、SHIMADA MITSUO
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 6 Pages: 3387-3392
- DOI
  10.21873/anticanres.12605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16257
[Journal Article] Usefulness of the Transoral Anvil Delivery System for Esophagojejunostomy After Laparoscopic Total Gastrectomy: A Single-institution Comparative Study of Transoral Anvil Delivery System and the Overlap Method.2018
- Author(s)
  Yoshikawa K, Shimada M, Higashijima J, Tokunaga T, Nishi M, Takasu C, Kashihara H, Ishikawa D
- Journal Title
  
  Surg Laparosc Endosc Percutan Tech.
  
  Volume: 28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015
[Journal Article] Epigallocatechin-3-gallate Enhances Radiation Sensitivity in Colorectal Cancer Cells Through Nrf2 Activation and Autophagy2018
- Author(s)
  ENKHBAT TUMENJIN、NISHI MASAAKI、YOSHIKAWA KOZO、JUN HIGASHIJIMA、TOKUNAGA TAKUYA、TAKASU CHIE、KASHIHARA HIDEYA、ISHIKAWA DAICHI、TOMINAGA MASAHIDE、SHIMADA MITSUO
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 11 Pages: 6247-6252
- DOI
  10.21873/anticanres.12980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16257
[Journal Article] The Outcome of Sorafenib Therapy on Unresectable Hepatocellular Carcinoma: Experience of Conversion and Salvage Hepatectomy2018
- Author(s)
  Yoshimoto T, Imura S, Morine Y, Ikemoto Y, Arakawa Y, Iwahashi S, Saito YU, Takasu C, Ishikawa D, Teraoku H, Bando Y, Shimada M
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 1 Pages: 501-507
- DOI
  10.21873/anticanres.12250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015, KAKENHI-PROJECT-18K16257
[Journal Article] Results of Hepatic Resection for Liver Metastasis of Gastric Cancer2018
- Author(s)
  Nishi M, Shimada M, Yoshikawa K, Higashijima J, Tokunaga J, Kashihara H, Takasu C, Ishikawa D, Wada Y, Eto S
- Journal Title
  
  J Med Invest.
  
  Volume: 65 Pages: 27-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015
[Journal Article] Elevated Preoperative Serum CEA Level Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma Through the Epithelial-Mesenchymal Transition.2017
- Author(s)
  Yoshikawa M, Morine Y, Ikemoto T, Imura S, Higashijima J, Iwahashi S, Saito YU, Takasu C, Yamada S, Ishikawa D, Teraoku H, Takata A, Yoshimoto T, Shimada M
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Issue: 3 Pages: 1169-1175
- DOI
  10.21873/anticanres.11430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015, KAKENHI-PROJECT-26293288, KAKENHI-PROJECT-16K10428
[Journal Article] High STAT4 Expression Indicates Better Disease-free Survival in Patients with Gastric Cancer2017
- Author(s)
  Nishi M, Batsaikhan BE, Yoshikawa K, Higashijima J, Tokunaga T, Takasu C, Kashihara H, Ishikawa D, Shimada M
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Issue: 12 Pages: 6723-6729
- DOI
  10.21873/anticanres.12131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015, KAKENHI-PROJECT-16K19896
[Journal Article] MicroRNA-449a deficiency promotes colon carcinogenesis2017
- Author(s)
  Niki Masanori、Nakajima Kohei、Ishikawa Daichi、Nishida Jun、Ishifune Chieko、Tsukumo Shin-ichi、Shimada Mitsuo、Nagahiro Shinji、Mitamura Yoshinori、Yasutomo Koji
- Journal Title
  
  Scientific Reports
  
  Volume: 7（1） Issue: 1 Pages: 10696-10696
- DOI
  10.1038/s41598-017-10500-0
- NAID
  120006535013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H07015, KAKENHI-PROJECT-15K08307, KAKENHI-PROJECT-15K19131
[Journal Article] Feasibility of Transanal Local Excision Following Chemoradiation for Lower Rectal Cancer2017
- Author(s)
  Tokunaga T, Nishi M, Higashijima J, Yoshikawa K, Kashihara H, Takasu C, Ishikawa D, Bando Y,Shimada M
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Issue: 10 Pages: 5617-5622
- DOI
  10.21873/anticanres.11996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015
[Journal Article] Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.2016
- Author(s)
  Wubetu GY, Shimada M, Morine Y, Ikemoto T, Ishikawa D, Iwahashi S, Yamada S, Saito Y, Arakawa Y, Imura S.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 1 Pages: 256-264
- DOI
  10.1111/jgh.13069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462092, KAKENHI-PROJECT-16H07015
[Journal Article] High NEK2 Expression Is a Predictor of Tumor Recurrence in Hepatocellular Carcinoma Patients After Hepatectomy.2016
- Author(s)
  Wubetu GY, Morine Y, Teraoku H, Yoshikawa M, Ishikawa D, Yamada S, Ikemoto T, Saito YU, Imura S, Shimada M
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 757-762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] 絞扼性イレウスを来たし緊急手術を行った大網裂孔ヘルニアの1例2019
- Author(s)
  石川大地、佐藤宏彦、豊田剛、鷹村和人、三浦連人
- Organizer
  第81回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-18K16257
[Presentation] 胃癌組織中に発現するmicroRNA-449aの意義解明についての研究2018
- Author(s)
  石川大地、高須千絵、柏原秀也、西正暁、徳永卓哉、東島潤、吉川耕造、島田光生
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K16257
[Presentation] 再発及び前立腺摘出術後の鼠径ヘルニア症例に対するTAPP法の有用性2018
- Author(s)
  石川大地、高須千絵、柏原秀也、西正暁、徳永卓哉、東島潤、吉川幸造、島田光生
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K16257
[Presentation] 大腸癌の発癌・腫瘍進展におけるmicroRNA-449aの役割解明2018
- Author(s)
  石川大地、高須千絵、柏原秀也、徳永卓哉、東島潤、吉川幸造、島田光生
- Organizer
  第51回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] Preoperative chemoradiotherapy for advanced lower rectal cancer using SOX+Bev regimen and role of microRNA-223 as a predictive indicator for the responder2017
- Author(s)
  Ishikawa D, Higashijima J, Takasu C, Kashihara H, Nishi M, Tokunaga T, Yoshikawa K, Shimada M
- Organizer
  Japanese Mongolian joint IX symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] 青色LED光の光受容体(opsin)を介した癌細胞増殖抑制効果の検討2017
- Author(s)
  石川大地、良元俊昭、島田光生、吉川幸造、東島潤、西正暁、柏原秀也、高須千絵
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] 局所進行下部直腸癌に対するSOX+Bevレジメンによる術前化学放射線療法と効果予測因子としてのmiR-223の役割2017
- Author(s)
  石川大地、東島潤、島田光生、吉川幸造、西正暁、柏原秀也、高須千絵
- Organizer
  第26回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] 大腸癌の発癌・腫瘍進展におけるmicroRNA-449aの役割解明2017
- Author(s)
  石川大地、良元俊昭、高須千絵、柏原秀也、東島潤、吉川幸造、島田光生
- Organizer
  第72回日本消化器外科学会
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] 大腸癌の発癌・腫瘍進展におけるmicroRNA-449aの意義2017
- Author(s)
  石川大地、良元俊昭、高田厚史、吉川雅登、齋藤裕、高須千絵、岩橋衆一、池本哲也、居村暁、森根裕二、島田光生
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] 転移性肝癌における腫瘍悪性度制御因子としてのTHBS-1の役割2016
- Author(s)
  石川大地, 寺奥大貴, 髙田厚史, 吉川雅登, 高須千絵, 齋藤裕, 岩橋衆一, 池本哲也, 居村暁, 森根裕二, 島田光生
- Organizer
  第27回日本消化器癌発生学会総会
- Place of Presentation
  城山観光ホテル(鹿児島県鹿児島市)
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] Signigficance of CD4+CD49b+regulatory T cells and Foxp3+regulatory T cells in the peripheral blood of cancer patients2016
- Author(s)
  Ishikawa D, Ikemoto T, Yoshimoto T, Takata A, Yoshikawa M,Takasu C, Saito Y, Iwahashi S, Morine Y, Imura S, Shimada M
- Organizer
  40th World Congress of the International College of Surgeons
- Place of Presentation
  京都国際会館(京都府京都市)
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07015
[Presentation] FBXW7発現は転移性肝癌における切除後再発予測因子となる2016
- Author(s)
  石川大地, 川下陽一郎, 良元俊昭, 髙田厚史, 吉川雅登, 齋藤裕, 岩橋衆一, 池本哲也, 森根裕二, 居村暁, 島田光生
- Organizer
  第54回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-16H07015

1. SHUICHI Iwahashi

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# of Collaborated Products: 1 results
2. YOSHIKAWA Kozo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 宇都宮徹

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# of Collaborated Products: 1 results
4. 居村暁

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# of Collaborated Products: 1 results
5. 森根裕二

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6. 池本哲也

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# of Collaborated Products: 1 results
7. 島田光生

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8. 西正暁

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9. 柏原秀也

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10. 徳永卓哉

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# of Collaborated Products: 1 results

Ishikawa Daichi 石川 大地

ISHIKAWA Daichi 石川 大地

Research Projects

Research Products

Co-Researchers

腫瘍関連線維芽細胞の脂質代謝に着目した腫瘍免疫制御のメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The impact of microRNA-449a on the cancer malignancy such as cancer stemness, epithelial-mesenchymal transition, and glycolysis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The moleculer mechanisms of epithelial to mesenchymeal transition of primary gastrointestinal tumor from the point of view of endodermal embryologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Role of Neutrophil-to-lymphocyte Ratio on the Effect of CRT for Patients With Rectal Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Utility of virtual three-dimensional image analysis for laparoscopic gastrectomy conducted by trainee surgeons2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Expression Level of MicroRNA-449a Predicts the Prognosis of Patients With Gastric Cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Significance of MicroRNA-449a and Its Potential Target HDAC1 in Patients With Colorectal Cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Usefulness of virtual three-dimensional image analysis in inguinal hernia as an educational tool2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Programmed Cell Death Ligand 1 Expression Is an Independent Prognostic Factor in Colorectal Cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Impact of Indoleamine 2,3-dioxygenase (IDO) Expression on Stage III Gastric Cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Usefulness of the Transoral Anvil Delivery System for Esophagojejunostomy After Laparoscopic Total Gastrectomy: A Single-institution Comparative Study of Transoral Anvil Delivery System and the Overlap Method.2018

Author(s)

Journal Title

Data Source

[Journal Article] Epigallocatechin-3-gallate Enhances Radiation Sensitivity in Colorectal Cancer Cells Through Nrf2 Activation and Autophagy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Outcome of Sorafenib Therapy on Unresectable Hepatocellular Carcinoma: Experience of Conversion and Salvage Hepatectomy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Results of Hepatic Resection for Liver Metastasis of Gastric Cancer2018

Author(s)

Journal Title

Data Source

[Journal Article] Elevated Preoperative Serum CEA Level Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma Through the Epithelial-Mesenchymal Transition.2017

Ishikawa Daichi 石川大地

ISHIKAWA Daichi 石川大地