MATSUMOTO HISATAKE 松本寿健

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Matsumoto Hisatake 松本寿健

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Researcher Number	70644003
Other IDs
Affiliation (Current)	2025: 大阪大学, 医学部附属病院, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2021 – 2025: 大阪大学, 医学部附属病院, 特任助教(常勤) 2020: 大阪大学, 医学部附属病院, 医員 2017: 大阪大学, 医学系研究科, 招へい教員 2016: 大阪大学, 医学系研究科, 特任研究員 2015: 大阪大学, 医学部附属病院, その他 2014 – 2015: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related Except Principal Investigator Basic Section 55060:Emergency medicine-related / Emergency medicine / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator クラッシュ症候群 / サブタイプ / 分子病態分類 / バイオインフォマティクス / 敗血症 / RNAシークエンス / NFκB / 集中治療医学 / 骨髄由来間葉系幹細胞移植 / 再生医療 … More / 幹細胞移植 / 骨髄由来間葉系幹細胞 / DNGR1 / DAMPｓ / ＤＮＧＲ１受容体 / Ｆアクチン / ＤＡＭＰｓ / DNGR１受容体 / Fアクチン … More Except Principal Investigator 敗血症 / 熱傷 / エピジェネテイクス / 質量分析 / トランスクリプトーム / RNA解析 / CyTOF / 炎症 / 侵襲 / 幹細胞 / 再生 / バイオマーカー / 臓器障害 / 頭部外傷 / 爆傷 / 衝撃波 / 全身性炎症反応 / Single cell analysis / Mass Cytometry / Immunology / T-cells / B-cells / CITEseq / scRNAseq / トランスクリプトーム解析 / エピジェネティクス / 慢性外傷性脳症 / 軽傷頭部外傷 / POU2F2 / 転写因子 / ジェネティクス / 統合解析 / 血管内皮 / ジェネテイクス / 幹細胞移植 / 多臓器障害 / 敗血症脳症 / 敗血症性脳症 / 予後 / 免疫応答 / MDSC / PIICS / 急性脳腫脹 / 外傷後早期痙攣 / 網羅的生体分子情報解析 / 網羅的蛋白発現解析 / 外傷後てんかん / 網羅的ゲノム解析 / 低ナトリウム血症 / サイトカイン / アディポカイン / 血管内皮障害 / CD63 / カドヘリン / GDF-15 / エクソソーム / Tカドヘリン / アディポネクチン / オートファジー / 気管支肺胞洗浄液 / 免疫フェノタイプ / 網羅的解析 / 肺局所免疫 / 肺炎 / BALF / 急性呼吸窮迫症候群 / RNAシークエンス / バイオインフォマティクス / 分子ネットワーク / 予後予測 / 心停止 / PD-1 / シングルセルRNA解析 / 免疫抑制 / 長寿 / 救急医学 / グリコカリックス / Arid-5 / IL-6 / 細胞移植 / 骨髄単核球細胞 / Extracellular vesicles / micro RNA / マイクロRNA / 自然免疫 / 全身炎症反応 / 脳損傷 / 迷走神経 / 反射 / 中枢神経 / 外傷外科学 / 活性化マクロファージ / 遅発性脳損傷 / Iba-1 / 行動試験 / うつ状態 / 記憶障害 / 制御性T細胞 / 外傷 / セプシス / B細胞 / 免疫細胞 / リンパ球 / 好中球 / CD4＋T細胞 / 免疫担当細胞 / 吸引痰 / フローサイトメトリー / 保存 / 痰 / T細胞 / インフラマソーム / 免疫 Less

Molecular Pathophysiological Role of the Novel Transcription Factor POU2F2 in Sepsis
- Principal Investigator
  
  光山裕美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  The University of Osaka
侵襲時再生治療に関する新規制御因子の解明：ゲノム・エピゲノム統合解析
- Principal Investigator
  
  小倉裕司
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
慢性期外傷性脳損傷はなぜ起きるのか -爆傷による軽症頭部外傷の病態を明らかにする-
- Principal Investigator
  
  米田和弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
敗血症におけるエピジェネティクス制御因子のメカニズム解明
- Principal Investigator
  
  横野良典
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Development of novels methods for single cell analysis of antigen specific cells
- Principal Investigator
  
  ウィングジェイムス
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University
免疫応答バランスからみた熱傷後の免疫不全メカニズムに関する統合的解析
- Principal Investigator
  
  大須賀章倫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
敗血症性脳症の分子病態統合解析と新規生体指標による積極的治療介入方法の提案
- Principal Investigator
  
  今村行雄
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kyoto University
網羅的生体分子情報に基づく重症熱傷病態の中心的分子解明と新規治療薬開発
- Principal Investigator
  
  大西伸也
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Immunomolecular pathogenesis of systemic and local lung immunity in ARDS based on integrated analysis
- Principal Investigator
  
  光山裕美
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
脂肪細胞による全身性炎症反応制御：オートファジーとアディポカイン産生
- Principal Investigator
  
  蛯原健
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
網羅的分子生体情報を用いた頭部外傷患者に対する新たな治療戦略の構築
- Principal Investigator
  
  中村洋平
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Elucidation of immunosuppressive mechanisms in sepsis using single-cell sequencing and development of novel therapeutic strategies
- Principal Investigator
  
  Ito Hiroshi
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Transcriptomic Analysis of Molecular Networks and Neurological Outcomes After Cardiac Arrest
- Principal Investigator
  
  Nakao Shunichiro
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Development of biomarker and molecular pathological classification for optimizing inflammation in sepsis:clinical application of HIVEP1Principal Investigator
- Principal Investigator
  
  Matsumoto Hisatake
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Profiling of circulating micro RNA expression in patients with sepsis
- Principal Investigator
  
  Umemura Yutaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
New developments in regenerative therapy for critical illness: the role of novel inflammatory amplification mechanisms.
- Principal Investigator
  
  Ogura Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Therapeutic effectiveness of human bone marrow mesenchymal stem cell transplantation in a rat model of crush InjuryPrincipal Investigator
- Principal Investigator
  
  Hisatake Matsumoto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Osaka University
Establishment of methods for immune response analysis of lymphocytes and neutrophils against sepsis and trauma
- Principal Investigator
  
  Shimizu Kentaro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Osaka University
Blast induced Traumatic Brain Injury and Cardiovascular Response
- Principal Investigator
  
  OHNISHI Mitsuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Osaka University
A new therapeutic strategy by suppression of F-actin/DNGR-1 signal in a rat model of crush injuryPrincipal Investigator
- Principal Investigator
  
  Matsumoto Hisatake
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Osaka University

All 2025 2024 2023 2020 2016

All Journal Article Presentation

[Journal Article] Relationship between growth differentiation factor 15 and functional prognosis and severity in traumatic brain injury2025
- Author(s)
  Ito Hiroshi、Ebihara Takeshi、Matsumoto Hisatake、Oda Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 15 Issue: 1 Pages: 2470-2470
- DOI
  10.1038/s41598-025-87062-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09140, KAKENHI-PROJECT-24K12153
[Journal Article] mRNA-miRNA integration analysis of T-cell exhaustion in sepsis from community-acquired pneumonia2025
- Author(s)
  Sayaka Oda, Hisatake Matsumoto, Yuki Togami, Jumpei Yoshimura, Hiroshi Ito, Shinya Onishi, Arisa Muratsu, Yumi Mitsuyama, Daisuke Okuzaki, Hiroshi Ogura, Susumu Tanaka Jun Oda
- Journal Title
  
  Acute Med Surg
  
  Volume: 12 Issue: 1
- DOI
  10.1002/ams2.70054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27701
[Journal Article] T cell dysfunction in elderly ARDS patients based on miRNA and mRNA integration analysis2024
- Author(s)
  Mitsuyama Yumi、Matsumoto Hisatake、Togami Yuki、Oda Sayaka、Onishi Shinya、Yoshimura Jumpei、Murtatsu Arisa、Ito Hiroshi、Ogura Hiroshi、Okuzaki Daisuke、Oda Jun
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15
- DOI
  10.3389/fimmu.2024.1368446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27671, KAKENHI-PROJECT-22K09132
[Journal Article] Atypical and non-classical CD45RBlo memory B cells are the majority of circulating SARS-CoV-2 specific B cells following mRNA vaccination or COVID-192024
- Author(s)
  Priest David G.、Ebihara Takeshi、Tulyeu Janyerkye、Sondergaard Jonas N.、Sakakibara Shuhei、Sugihara Fuminori、Nakao Shunichiro、Togami Yuki、Yoshimura Jumpei、Ito Hiroshi、Onishi Shinya、Muratsu Arisa、Mitsuyama Yumi、Ogura Hiroshi、Oda Jun、Okusaki Daisuke、Matsumoto Hisatake、Wing James B.
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-21
- DOI
  10.1038/s41467-024-50997-4
- Data Source
  KAKENHI-PROJECT-21K09017, KAKENHI-PROJECT-22K09132
[Journal Article] Bacterial sepsis causes more dramatic pathogenetic changes in the Th1 pathway than does viral (COVID-19) sepsis: a prospective observational study of whole blood transcriptomes2024
- Author(s)
  Muratsu Arisa、Oda Sayaka、Onishi Shinya、Yoshimura Jumpei、Matsumoto Hisatake、Togami Yuki、Mitsuyama Yumi、Ito Hiroshi、Okuzaki Daisuke、Ogura Hiroshi、Oda Jun
- Journal Title
  
  Virology Journal
  
  Volume: 21 Issue: 1
- DOI
  10.1186/s12985-024-02451-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27671, KAKENHI-PROJECT-22K09132
[Journal Article] Ultrasound stimulation of the vagal nerve improves acute septic encephalopathy in mice2023
- Author(s)
  Imamura Yukio、Matsumoto Hisatake、Imamura Jun、Matsumoto Naoya、Yamakawa Kazuma、Yoshikawa Nao、Murakami Yuki、Mitani Satoko、Nakagawa Junichiro、Yamada Tomoki、Ogura Hiroshi、Oda Jun、Shimazu Takeshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 1-14
- DOI
  10.3389/fnins.2023.1211608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08475, KAKENHI-PROJECT-20K21587
[Journal Article] Bone Marrow-Derived Mononuclear Cell Transplantation can Reduce Systemic Inflammation and Endothelial Glycocalyx Damage in Sepsis2020
- Author(s)
  Matsubara Tsunehiro、Umemura Yutaka、Ogura Hiroshi、Matsuura Hiroshi、Ebiharara Takeshi、Matsumoto Hisatake、Yamakawa Kazuma、Shimizu Kentarou、Okada Hideshi、Shimazu Takeshi
- Journal Title
  
  Shock
  
  Volume: Publish Ahead of Print Issue: 2 Pages: 260-267
- DOI
  10.1097/shk.0000000000001710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03756, KAKENHI-PROJECT-19H03760
[Presentation] Analysis of Gene Expressions in Post-Cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest2025
- Author(s)
  Shunichiro Nakao, Yoshinori Yokono, Yumi Mitsuyama, Takeshi Ebihara, Hisatake Matsumoto, Jun Oda
- Organizer
  The 5th Joint Scientific Congress of TSCCM (Thai) and JSICM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09018
[Presentation] Analysis of Gene Expressions in Post-Cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest2025
- Author(s)
  Shunichiro Nakao, Yoshinori Yokono, Yumi Mitsuyama, Takeshi Ebihara, Hisatake Matsumoto, Jun Oda
- Organizer
  第52回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09018
[Presentation] サイトカインプロファイルによる敗血症患者の予後の評価2016
- Author(s)
  松本寿健, 清水健太郎, 池田光憲, 廣瀬智也, Kang Suijin, 小倉裕司, 田中敏郎, 嶋津岳士
- Organizer
  第44回日本救急医学会
- Place of Presentation
  グランドプリンスホテル高輪
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K10979

1. Ogura Hiroshi (70301265)

# of Collaborated Projects: 13 results

# of Collaborated Products: 4 results
2. Shimizu Kentaro (60379203)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
3. 奥崎大介 (00346131)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
4. 嶋津岳士 (50196474)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
5. 蛯原健 (10813975)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
6. 杉原文徳 (50381645)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. OHNISHI Mitsuo (70597830)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MATSUURA Hiroshi (10791709)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Umemura Yutaka (20743561)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Ito Hiroshi (80836594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 吉矢和久 (40379201)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 山川一馬 (50597507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 藤見聡 (70362720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 入澤太郎 (50379202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 大西伸也 (60892932)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 大須賀章倫 (60552081)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 光山裕美 (20787882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. ウィングジェイムス (00648694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 戸上由貴 (50866936)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 米田和弘 (90975137)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. HOSOMI Sanae (90644005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Nakao Shunichiro (80834150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 高橋弘毅 (30609590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 池田光憲 (60548444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 姜晋求 (50721114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 廣瀬智也 (70597509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 福田士郎 (00896467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 喜多俊文 (10746572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 中村洋平 (80644004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 今村行雄 (90447954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 村上由希 (50580106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. 織田順 (60459500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 横野良典 (00986911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 吉村旬平 (30835202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 西田岳史 (30986914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 坂口志文 (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 岡田英志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUMOTO HISATAKE 松本 寿健

Matsumoto Hisatake 松本 寿健

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Development of biomarker and molecular pathological classification for optimizing inflammation in sepsis:clinical application of HIVEP1Principal Investigator

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MATSUMOTO HISATAKE 松本寿健

Matsumoto Hisatake 松本寿健