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Nukaga Shigenari  額賀 重成

ORCIDConnect your ORCID iD *help
Researcher Number 70645613
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 助教
Affiliation (based on the past Project Information) *help 2025: 慶應義塾大学, 医学部(信濃町), 助教
2016 – 2019: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field
Principal Investigator
Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine
Keywords
Principal Investigator
非小細胞肺癌 / 耐性化機序 / EGFR-TKI / 血管新生阻害薬 / imaging massspectrometry / 腫瘍内代謝 / 分子標的薬 / 肺癌
  • Research Projects

    (3 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (4 People)
  •  RNAスプライシング解析に基づくドライバー変異陰性肺癌の新規治療標的の同定Principal Investigator

    • Principal Investigator
      額賀 重成
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Keio University
  •  Analysis of resistance mechanism to third generation EGFR-TKI and clinical applicationPrincipal Investigator

    • Principal Investigator
      Nukaga Shigenari
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Keio University
  •  Elucidation of pharmacokinetics of molecular targeted drugs by Imaging massspectrometryPrincipal Investigator

    • Principal Investigator
      Nukaga Shigenari
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Keio University

All 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Amplification of EGFR Wild-Type Alleles in Non-Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors.2017

    • Author(s)
      Nukaga S, Yasuda H, Tsuchihara K, Hamamoto J, Masuzawa K, Kawada I, Naoki K, Matsumoto S, Mimaki S, Ikemura S, Goto K, Betsuyaku T, Soejima K.
    • Journal Title

      Cancer Research

      Volume: 77(8) Issue: 8 Pages: 2078-2089

    • DOI

      10.1158/0008-5472.can-16-2359

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H05666, KAKENHI-PROJECT-15K14398, KAKENHI-PROJECT-15K09229, KAKENHI-PROJECT-16K19465
  • [Presentation] 血管新生阻害剤が肺癌細胞の代謝に与える影響の検討2018

    • Author(s)
      増澤啓太、荒井大輔、安田浩之、額賀重成、川田一郎、猶木克彦、江本桂、杉浦悠毅、末松誠、副島研造、別役智子
    • Organizer
      第58回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-16K19465
  • [Presentation] Imaging-massspectrometry(MS)を用いたBIBF1120による腫瘍内代謝に与える影響についての検討2016

    • Author(s)
      額賀 重成
    • Organizer
      第56回日本呼吸器学会学術講演会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-04-10
    • Data Source
      KAKENHI-PROJECT-16K19465
  • 1.  SOEJIMA Kenzo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  YASUDA Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  MASUZAWA Keita
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  ARAI Daisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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