Tamura Ryo 田村亮

Researcher Number	70650620
Other IDs
Affiliation (Current)	2025: 新潟大学, 医歯学系, 講師 2025: 新潟大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2021 – 2025: 新潟大学, 医歯学総合研究科, 客員研究員 2018 – 2022: 新潟大学, 医歯学総合病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 扁平上皮癌 / 成熟嚢胞性奇形腫悪性転化 / 全エクソンシーケンス / 抗PD1/PD-L1抗体 / XCL1 / personized therapy / tissue factor / microenvironment / hypercoagulation / RNA シーケンス … More / マルチサンプリング / 腫瘍内異質性 / 卵巣成熟嚢胞性奇形腫悪性転化 / 悪性転化 / 卵巣成熟奇形腫 / 免疫チェックポイント阻害薬 / APOBEC / 腫瘍内不均一性 / 卵巣成熟奇形腫悪性転化 / UPK3B-PMS2 / TACSTD2-OMA1 / FGFR3-TACC3 / 融合遺伝子 / PD-L1 / CD8 / RMAシーケンス / PIK3CA / TP53 / RNAシーケンス / 卵巣成熟嚢胞性奇形腫 … More Except Principal Investigator 子宮内膜症 / 子宮内膜 / 正常子宮内膜 / ゲノム / 卵巣癌 / 質量分析 / オルガノイド / 地下茎構造 / 癌関連遺伝子 / 内膜症関連卵巣癌 / 癌遺伝子 / シングルセルシークエンス / 単一腺管シークエンス / 明細胞癌 / 単一細胞シークエンス / 卵巣類内膜癌 Less

Elucidation of the pathologenesis of endometrium-related diseases based on the rhizome in uterine endometrium
- Principal Investigator
  
  吉原弘祐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University
子宮内膜オルガノイドを用いた子宮内膜症の病態解明
- Principal Investigator
  
  安達聡介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University
Novel therapeutic strategy for ovarian clear cell carcinoma focusing on hypercoagulation and tumor Immune microenvironmentPrincipal Investigator
- Principal Investigator
  
  田村亮
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University
Novel therapeutic strategy based on XCL1 expression for squamous cell carcinoma arising from mature cystic teratoma of the ovaryPrincipal Investigator
- Principal Investigator
  
  Tamura Ryo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University
Elucidation of the pathogenesis of ovarian endometrioid carcinoma using single cell sequencing
- Principal Investigator
  
  Adachi Sosuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University
Identification of pathogenesis of ovarian clear cell carcinoma by topographic single cell sequencing
- Principal Investigator
  
  Enomoto Takayuki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Niigata University
Elucidation of pathogenesis of endometriosis and endometriosis-associated ovarian cancer based on genomic analyses for normal endometrium
- Principal Investigator
  
  ENOMOTO Takayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University
Molecular characterization of carcinoma arising in mature cystic teratoma of the ovaryPrincipal Investigator
- Principal Investigator
  
  Tamura Ryo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Niigata University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Refractory ovarian squamous cell carcinoma arising from a seromucinous borderline tumor with squamous overgrowth: A case report2024
- Author(s)
  Ryo Tamura, Naohisa Kushiya, Masayuki Yamaguchi, Nobumichi Nishikawa, Teiichi Motoyama, Takashi Kawasaki, Akira Kikuchi
- Journal Title
  
  Gynecologic Oncology Reports
  
  Volume: 51 Pages: 101323-101323
- DOI
  10.1016/j.gore.2024.101323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16785
[Journal Article] Spatial genomic diversity associated with <scp>APOBEC</scp> mutagenesis in squamous cell carcinoma arising from ovarian teratoma2023
- Author(s)
  Tamura Ryo、Nakaoka Hirofumi、Yachida Nozomi、Ueda Haruka、Ishiguro Tatsuya、Motoyama Teiichi、Inoue Ituro、Enomoto Takayuki、Yoshihara Kosuke
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 5 Pages: 2145-2157
- DOI
  10.1111/cas.15754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09635, KAKENHI-PROJECT-21K16785, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K27447
[Journal Article] Successful treatment of advanced squamous cell carcinoma arising from mature cystic teratoma of the ovary with homologous recombination deficiency: A case report2023
- Author(s)
  Ryo Tamura, Masayuki Yamaguchi, Yohei Kitani, Nobumichi Nishikawa, Takashi Kawasaki, Akira Kikuchi
- Journal Title
  
  International Journal of Surgery Case Reports
  
  Volume: 107 Pages: 108329-108329
- DOI
  10.1016/j.ijscr.2023.108329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16785
[Journal Article] Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium2022
- Author(s)
  Yamaguchi Manako、Nakaoka Hirofumi、Suda Kazuaki、Yoshihara Kosuke、Ishiguro Tatsuya、Yachida Nozomi、Saito Kyota、Ueda Haruka、Sugino Kentaro、Mori Yutaro、Yamawaki Kaoru、Tamura Ryo、Revathidevi Sundaramoorthy、Motoyama Teiichi、Tainaka Kazuki、Verhaak Roel G. W.、Inoue Ituro、Enomoto Takayuki
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 943-943
- DOI
  10.1038/s41467-022-28568-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09822, KAKENHI-PROJECT-20K21246, KAKENHI-PROJECT-20K21647, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-20H03821, KAKENHI-PROJECT-20K07318, KAKENHI-PROJECT-16H06279
[Journal Article] The New Era of Three-Dimensional Histoarchitecture of the Human Endometrium2021
- Author(s)
  Yamaguchi Manako、Yoshihara Kosuke、Yachida Nozomi、Suda Kazuaki、Tamura Ryo、Ishiguro Tatsuya、Enomoto Takayuki
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 11 Issue: 8 Pages: 713-713
- DOI
  10.3390/jpm11080713
- Data Source
  KAKENHI-PROJECT-20K21647
[Journal Article] Establishment of in vitro 3D spheroid cell cultivation from human gynecologic cancer tissues2021
- Author(s)
  Ueda Haruka、Mori Yutaro、Yamawaki Kaoru、Ishiguro Tatsuya、Ohata Hirokazu、Sato Ai、Sugino Kentaro、Yachida Nozomi、Yamaguchi Manako、Suda Kazuaki、Tamura Ryo、Yoshihara Kosuke、Okamoto Koji、Enomoto Takayuki
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 1 Pages: 100354-100354
- DOI
  10.1016/j.xpro.2021.100354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09023, KAKENHI-PROJECT-20K21647, KAKENHI-PROJECT-20H03821, KAKENHI-PROJECT-18K09250, KAKENHI-PROJECT-21K09490
[Journal Article] Three-dimensional understanding of the morphological complexity of the human uterine endometrium2021
- Author(s)
  Yamaguchi Manako、Yoshihara Kosuke、Suda Kazuaki、Nakaoka Hirofumi、Yachida Nozomi、Ueda Haruka、Sugino Kentaro、Mori Yutaro、Yamawaki Kaoru、Tamura Ryo、Ishiguro Tatsuya、Motoyama Teiichi、Watanabe Yu、Okuda Shujiro、Tainaka Kazuki、Enomoto Takayuki
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 4 Pages: 102258-102258
- DOI
  10.1016/j.isci.2021.102258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09822, KAKENHI-PROJECT-20K21246, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-20H03821, KAKENHI-PROJECT-20K21647, KAKENHI-PROJECT-20K07318
[Journal Article] How Does Endometriosis Lead to Ovarian Cancer? The Molecular Mechanism of Endometriosis-Associated Ovarian Cancer Development2021
- Author(s)
  Yachida Nozomi、Yoshihara Kosuke、Yamaguchi Manako、Suda Kazuaki、Tamura Ryo、Enomoto Takayuki
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 6 Pages: 1439-1439
- DOI
  10.3390/cancers13061439
- Data Source
  KAKENHI-PROJECT-20K21647
[Journal Article] Proposing a molecular classification associated with hypercoagulation in ovarian clear cell carcinoma2021
- Author(s)
  Tamura Ryo、Yoshihara Kosuke、Matsuo Koji、Yachida Nozomi、Miyoshi Ai、Takahashi Kotaro、Sugino Kentaro、Yamaguchi Manako、Mori Yutaro、Suda Kazuaki、Ishiguro Tatsuya、Okuda Shujiro、Motoyama Teiichi、Nakaoka Hirofumi、Kikuchi Akira、Ueda Yutaka、Inoue Ituro、Enomoto Takayuki
- Journal Title
  
  Gynecologic Oncology
  
  Volume: 163 Issue: 2 Pages: 327-333
- DOI
  10.1016/j.ygyno.2021.08.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09822, KAKENHI-PROJECT-20K21647, KAKENHI-PROJECT-16H06279
[Journal Article] Biological significance of KRAS mutant allele expression in ovarian endometriosis2021
- Author(s)
  Yachida Nozomi、Yoshihara Kosuke、Suda Kazuaki、Nakaoka Hirofumi、Ueda Haruka、Sugino Kentaro、Yamaguchi Manako、Mori Yutaro、Yamawaki Kaoru、Tamura Ryo、Ishiguro Tatsuya、Kase Hiroaki、Motoyama Teiichi、Enomoto Takayuki
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 5 Pages: 2020-2032
- DOI
  10.1111/cas.14871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09822, KAKENHI-PROJECT-20K21647, KAKENHI-PROJECT-20H03821, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K07318
[Journal Article] XCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary2020
- Author(s)
  Tamura Ryo、Yoshihara Kosuke、Nakaoka Hirofumi、Yachida Nozomi、Yamaguchi Manako、Suda Kazuaki、Ishiguro Tatsuya、Nishino Koji、Ichikawa Hiroshi、Homma Keiichi、Kikuchi Akira、Ueda Yutaka、Takei Yuji、Fujiwara Hiroyuki、Motoyama Teiichi、Okuda Shujiro、Wakai Toshifumi、Inoue Ituro、Enomoto Takayuki
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 17 Pages: 3541-3554
- DOI
  10.1038/s41388-020-1237-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09822, KAKENHI-PROJECT-17H04336, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K07318, KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-18K16760
[Journal Article] ARID1A protein expression is retained in ovarian endometriosis with ARID1A loss-of-function mutations: implication for the two-hit hypothesis2020
- Author(s)
  Yachida Nozomi、Yoshihara Kosuke、Suda Kazuaki、Nakaoka Hirofumi、Ueda Haruka、Sugino Kentaro、Yamaguchi Manako、Mori Yutaro、Yamawaki Kaoru、Tamura Ryo、Ishiguro Tatsuya、Isobe Masanori、Motoyama Teiichi、Inoue Ituro、Enomoto Takayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 14260-14260
- DOI
  10.1038/s41598-020-71273-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09822, KAKENHI-PROJECT-20K07318, KAKENHI-PROJECT-20K21647, KAKENHI-PROJECT-20H03821, KAKENHI-PROJECT-16H06279
[Presentation] マルチオミックス統合解析に基づいた難治性卵巣がんの新規治療戦略2024
- Author(s)
  田村亮
- Organizer
  第76回産科婦人科学会総会　シンポジウム
- Data Source
  KAKENHI-PROJECT-21K16785
[Presentation] がん遺伝子検査が治療選択に有効であった難治性卵巣扁平上皮癌の2例2023
- Author(s)
  田村亮、櫛谷直寿、山口雅幸、西川伸道、菊池朗
- Organizer
  R5年新潟大学産婦人科同窓会集談会
- Data Source
  KAKENHI-PROJECT-21K16785
[Presentation] XCL1 expression as a diagnostic biomarker and a possible biomarker of immune checkpoint inhibitor therapy for squamous cell carcinoma arising from mature cystic teratoma of the ovary2020
- Author(s)
  Ryo Tamura, Kosuke Yoshihara, Nozomi Yachida, Manako Yamaguchi, Kazuaki Suda, Tatsuya Ishiguro, Koji Nishino, Akira Kikuchi, Yutaka Ueda, Yuji Takei, Hiroyuki Fujiwara and Takayuki Enomoto
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K16760
[Presentation] 卵巣成熟嚢胞性奇形腫悪性転化に対するオミックスデータ解析～新規治療戦略の構築を目指して～2019
- Author(s)
  田村亮
- Organizer
  第6回新潟産婦人科シンポジウム
- Data Source
  KAKENHI-PROJECT-18K16760

1. 吉原弘祐 (40547535)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. Adachi Sosuke (50613147)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Enomoto Takayuki (90283754)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 井ノ上逸朗 (00192500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 石黒竜也 (80625690)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 中岡博史 (70611193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 田井中一貴 (80506113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 須田一暁 (80650621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森裕太郎 (80883313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 杉山栄二 (90806332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tamura Ryo 田村 亮

Research Projects

Research Products

Co-Researchers

Elucidation of the pathologenesis of endometrium-related diseases based on the rhizome in uterine endometrium

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

子宮内膜オルガノイドを用いた子宮内膜症の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel therapeutic strategy for ovarian clear cell carcinoma focusing on hypercoagulation and tumor Immune microenvironmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel therapeutic strategy based on XCL1 expression for squamous cell carcinoma arising from mature cystic teratoma of the ovaryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of ovarian endometrioid carcinoma using single cell sequencing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of pathogenesis of ovarian clear cell carcinoma by topographic single cell sequencing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathogenesis of endometriosis and endometriosis-associated ovarian cancer based on genomic analyses for normal endometrium

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular characterization of carcinoma arising in mature cystic teratoma of the ovaryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Refractory ovarian squamous cell carcinoma arising from a seromucinous borderline tumor with squamous overgrowth: A case report2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatial genomic diversity associated with <scp>APOBEC</scp> mutagenesis in squamous cell carcinoma arising from ovarian teratoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful treatment of advanced squamous cell carcinoma arising from mature cystic teratoma of the ovary with homologous recombination deficiency: A case report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The New Era of Three-Dimensional Histoarchitecture of the Human Endometrium2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of in vitro 3D spheroid cell cultivation from human gynecologic cancer tissues2021

Author(s)

Journal Title

Tamura Ryo 田村亮

[Presentation] マルチオミックス統合解析に基づいた難治性卵巣がんの新規治療戦略2024

[Presentation] がん遺伝子検査が治療選択に有効であった難治性卵巣扁平上皮癌の2例2023

[Presentation] 卵巣成熟嚢胞性奇形腫悪性転化に対するオミックスデータ解析～新規治療戦略の構築を目指して～2019