• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Sugiyama Hirokazu  杉山 弘和

ORCIDConnect your ORCID iD *help
… Alternative Names

SUGIYAMA Hirokazu  杉山 弘和

Less
Researcher Number 70701340
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院工学系研究科(工学部), 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 東京大学, 大学院工学系研究科(工学部), 教授
2016 – 2020: 東京大学, 大学院工学系研究科(工学部), 准教授
2017: 東京大学, 大学院工学系研究科, 准教授
2013 – 2015: 東京大学, 工学(系)研究科(研究院), 准教授
2013: 東京大学, 大学院・工学系研究科, 准教授
Review Section/Research Field
Principal Investigator
Reaction engineering/Process system / Medium-sized Section 27:Chemical engineering and related fields / Basic Section 27020:Chemical reaction and process system engineering-related
Except Principal Investigator
Basic Section 27020:Chemical reaction and process system engineering-related / Social systems engineering/Safety system / Recycling engineering
Keywords
Principal Investigator
プロセス設計 / モデル化 / シミュレーション / 医薬品製造 / モデリング / 最適化 / ヒトiPS細胞 / iPS細胞 / 意思決定 / 多目的意思決定 … More / 注射剤 / プロセスシステム工学 / 単位操作 / 幹細胞培養 / パンデミック治療薬 / 診断・治療用ナノ粒子 / デュアルユース / ワクチン・治療薬 / ダイナミックシミュレーション / 感染症数理モデル / コンパニオン診断 / 感染予測 / COVID-19 / 治療薬供給 / ワクチン供給 / パンデミック / 医薬品製造プロセス / 凍結プロセス / 環境影響評価 / 保護剤 / ライフサイクルアセスメント / 計算化学 / 解凍 / 凍結 / 計算科学 / CFD / 費用対効果 / 多目的最適化 / ハイブリッドモデリング / 凍結保護剤 / ソフトウエア / 化学工学 / データ駆動型 / 多目的プロセス設計 / 感度解析 / 多目的評価 / ソフトウェア実装 / アルゴリズム / 医薬品開発 / 社会実装 / ソフトウェア / 固形剤 / バイオ医薬品 / 連続生産 / シングルユース / 数理モデル / スーパーストラクチャー / 注射剤製造 / 多目的設計 / 製剤製造 / 原薬製造 / 環境・健康・安全リスク / 製造技術選択 / 製品ロス低減 / プロセス改善 / 経済性 / 固形製剤 / 環境安全 / 生産性 / 品質 / 原薬 / 生産工学 / コスト削減 / 品質管理 … More
Except Principal Investigator
リサイクル / 機械学習 / デインスペース / モデリング / プロセス設計 / デジタルツイン / 制御 / モデル / デザインスペース / 製剤 / 異常検出 / プロセス制御 / 管理戦略 / 連続生産 / 医薬品 / シミュレーションモデル / 内部短絡 / 事故事例分析 / 難燃性電解液 / フォールトの木解析 / 環境負荷 / リユース / 安全設計 / フォルトツリー解析 / ライフサイクル / リチウムイオン電池 / 製品安全設計 / システム安全 / 紙 / 国際情報交換(台湾) / 環境政策 / LCA / 消費者行動 / 素材間連関 / 容器包装 / プラスチック / シナリオ分析 / 物質循環 / LCA / マテリアルフロー Less
  • Research Projects

    (9 results)
  • Research Products

    (288 results)
  • Co-Researchers

    (12 People)
  •  Multiscale design platform for stem cell cultivation processesPrincipal Investigator

    • Principal Investigator
      杉山 弘和
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 27:Chemical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  Development of innovative management strategy for pharmaceutical continuous manufacturing processes

    • Principal Investigator
      Kano Manabu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27020:Chemical reaction and process system engineering-related
    • Research Institution
      Kyoto University
  •  Development of rapid production-production support systems for pandemic drugsPrincipal Investigator

    • Principal Investigator
      杉山 弘和
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27020:Chemical reaction and process system engineering-related
    • Research Institution
      The University of Tokyo
  •  Multiscale design platform for innovating freezing processes of iPS cellsPrincipal Investigator

    • Principal Investigator
      Sugiyama Hirokazu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 27:Chemical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  Development of innovative process design methodology for pharmaceutical manufacturing and tool implementationPrincipal Investigator

    • Principal Investigator
      Sugiyama Hirokazu
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Reaction engineering/Process system
    • Research Institution
      The University of Tokyo
  •  Safety design method of Lithium ion battery using systems approach

    • Principal Investigator
      Hirao Masahiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Social systems engineering/Safety system
    • Research Institution
      The University of Tokyo
  •  Development of multiobjective process design method for quality and productivity improvement in pharmaceutical manufacturingPrincipal Investigator

    • Principal Investigator
      Sugiyama Hirokazu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Reaction engineering/Process system
    • Research Institution
      The University of Tokyo
  •  製薬プロセスの品質・生産性向上にむけた意思決定支援手法の開発Principal Investigator

    • Principal Investigator
      杉山 弘和
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Reaction engineering/Process system
    • Research Institution
      The University of Tokyo
  •  Material flow model for the evaluation of recycling considering relations between different materials

    • Principal Investigator
      HIRAO Masahiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Recycling engineering
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent

  • [Book] "Design Framework and Tools for Solid Drug Product Manufacturing Processes" in "Optimization of Pharmaceutical Processes"2022

    • Author(s)
      Kensaku Matsunami, Sara Badr, Hirokazu Sugiyama
    • Total Pages
      435
    • Publisher
      Springer
    • ISBN
      9783030909246
    • Data Source
      KAKENHI-PROJECT-21H01704
  • [Book] 固形剤の連続製造プロセス設計と経済性評価2020

    • Author(s)
      松並 研作, 杉山 弘和
    • Total Pages
      9
    • Publisher
      技術情報協会
    • ISBN
      9784861048203
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Book] "連続生産を対象とするプロセスシステム工学研究" 固形製剤とバイオ原薬の連続生産2019

    • Author(s)
      杉山 弘和, 松並 研作
    • Total Pages
      10
    • Publisher
      シーエムシー出版
    • ISBN
      9784781314259
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Book] 注射剤製造における無菌性保証・バリデーションと異物低減ノウハウ・検査事例2016

    • Author(s)
      杉山 弘和
    • Total Pages
      23
    • Publisher
      サイエンスアンドテクノロジー
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Book] 抗体医薬における細胞構築・培養・ダウンストリームのすべて 第8編第1章 医薬品生産における統合化工学とは2015

    • Author(s)
      杉山 弘和(分担著者) 大政 健史(監修)
    • Total Pages
      7
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Book] “医薬品生産における統合化工学とは” 抗体医薬品における細胞構築・培養・ダウンストリームのすべて, 大政健史(編)2015

    • Author(s)
      杉山 弘和
    • Total Pages
      9
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] A CFD model-based design of seeding processes for two-dimensional mesenchymal stem cell cultivation2023

    • Author(s)
      Scholz Benedikt X., Hayashi Yusuke, Udugama Isuru A., Kino-oka Masahiro, Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 171 Pages: 108157-108157

    • DOI

      10.1016/j.compchemeng.2023.108157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] A screening support method of cryoprotective agents for regenerative medical products considering environmental impacts2023

    • Author(s)
      Hayashi Yusuke, Shigeyama Akinori, Sugiyama Hirokazu
    • Journal Title

      Chemical Engineering Research and Design

      Volume: 191 Pages: 83-92

    • DOI

      10.1016/j.cherd.2023.01.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes2023

    • Author(s)
      Kensaku Matsunami, Tomohiro Miura, Keita Yaginuma, Shuichi Tanabe, Sara Badr, Hirokazu Sugiyama
    • Journal Title

      Computers & Chemical Engineering

      Volume: 171 Pages: 108141-108141

    • DOI

      10.1016/j.compchemeng.2023.108141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H01704
  • [Journal Article] 生産性と品質を考慮したヒトiPS細胞向け充填・凍結・解凍プロセスのハイブリッドモデルベースと設計2022

    • Author(s)
      林 勇佑, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 38 Pages: 585-588

    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] Cost-effectiveness analysis in the manufacture of allogeneic human induced pluripotent cells in Japan by agent-based modeling2022

    • Author(s)
      Hayashi Yusuke、Oishi Kota、Sugiyama Hirokazu
    • Journal Title

      Chemical Engineering Research and Design

      Volume: 182 Pages: 172-182

    • DOI

      10.1016/j.cherd.2022.03.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] Hybrid-model-based design of fill-freeze-thaw processes for human induced pluripotent stem cells considering productivity and quality2022

    • Author(s)
      Hayashi Yusuke、Kino-oka Masahiro、Sugiyama Hirokazu
    • Journal Title

      Computers and Chemical Engineering

      Volume: 156 Pages: 107566-107566

    • DOI

      10.1016/j.compchemeng.2021.107566

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] Pharma PSE Spotlight 第14回:生産性と品質を考慮したヒトiPS細胞向け充填・凍結・解凍プロセスのハイブリッドモデルベースと設計2022

    • Author(s)
      林 勇佑、杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 38 Pages: 585-588

    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] A multilayered approach to scale-up forced convection-based freezing of human induced pluripotent stem cells2022

    • Author(s)
      Scholz Benedikt X., Hayashi Yusuke, Udugama Isuru A., Kino-oka Masahiro, Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 163 Pages: 107851-107851

    • DOI

      10.1016/j.compchemeng.2022.107851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells2021

    • Author(s)
      Hayashi Yusuke, Horiguchi Ikki, Kino-oka Masahiro, Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 144 Issue: 11 Pages: 107150-107150

    • DOI

      10.1002/term.3127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Computational screening of cryoprotective agents for regenerative medical products using quantum chemistry and molecular dynamics simulations2021

    • Author(s)
      Hayashi Yusuke, Nakajima Yuka, Sugiyama Hirokazu
    • Journal Title

      Cryobiology

      Volume: in press Pages: 101-109

    • DOI

      10.1016/j.cryobiol.2021.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102, KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第13回:ヒトiPS細胞の緩慢凍結プロセスにおける冷却温度プロファイルのモデルベースト評価2021

    • Author(s)
      林 勇佑, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 37 Pages: 255-259

    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] 固形剤製造プロセスの経済性評価シミュレーションとツール実装2021

    • Author(s)
      杉山 弘和, 松並 研作
    • Journal Title

      化学装置

      Volume: 1 Pages: 57-62

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells2021

    • Author(s)
      Hayashi Yusuke, Horiguchi Ikki, Kino-oka Masahiro, Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 144 Pages: 107150-107150

    • DOI

      10.1016/j.compchemeng.2020.107150

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102, KAKENHI-PROJECT-17H04964
  • [Journal Article] Determination of critical decision points for COVID-19 measures in Japan2021

    • Author(s)
      Kim Junu、Matsunami Kensaku、Okamura Kozue、Badr Sara、Sugiyama Hirokazu
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 107541-107541

    • DOI

      10.1038/s41598-021-95617-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K21057
  • [Journal Article] Determining key parameters of continuous wet granulation for tablet quality and productivity: A case in ethenzamide2020

    • Author(s)
      Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Hirokazu Sugiyama
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 579 Pages: 119160-119160

    • DOI

      10.1016/j.ijpharm.2020.119160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
  • [Journal Article] Pharma PSE Spotlight 第12回:無菌製剤製造における除染プロセスとスケジューリングの統合設計2020

    • Author(s)
      藪田 啓奨, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 36 Pages: 2421-2426

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Apoptosis‐based method for determining lot sizes in the filling of human‐induced pluripotent stem cells2020

    • Author(s)
      Sugiyama Hirokazu, Shiokaramatsu Masaki, Kagihiro Masashi, Fukumori Kazuhiro, Horiguchi Ikki, Kino‐oka Masahiro
    • Journal Title

      Journal of Tissue Engineering and Regenerative Medicine

      Volume: 14 Issue: 9 Pages: 1641-1651

    • DOI

      10.1016/j.xphs.2020.05.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] 固形製剤の製法設計のためのシミュレーションツール2020

    • Author(s)
      松並 研作, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 36 Pages: 1257-1262

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing2020

    • Author(s)
      Kensaku Matsunami, Fabian Sternal, Keita Yaginuma, Shuichi Tanabe, Hiroshi Nakagawa, Hirokazu Sugiyama
    • Journal Title

      BMC Chemical Engineering

      Volume: 2 Issue: 1 Pages: 6-6

    • DOI

      10.1186/s42480-020-0028-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
  • [Journal Article] Multi-stage and multi-objective decision-support tool for biopharmaceutical drug product manufacturing: Equipment technology evaluation2020

    • Author(s)
      Z?rcher Philipp, Shirahata Haruku, Badr Sara, Sugiyama Hirokazu
    • Journal Title

      Chemical Engineering Research and Design

      Volume: 161 Pages: 240-252

    • DOI

      10.1016/j.cherd.2020.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第13回:ヒトiPS細胞の緩慢凍結プロセスにおける冷却温度プロファイルのモデルベースト評価2020

    • Author(s)
      林 勇佑, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 37 Pages: 255-259

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Integrated design of H2O2 decontamination processes and scheduling in sterile drug product manufacturing2020

    • Author(s)
      Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Hirokazu Sugiyama
    • Journal Title

      Journal of Pharmaceutical Innovation

      Volume: accepted Issue: 1 Pages: 38-52

    • DOI

      10.1007/s12247-019-09410-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Multiobjective Dynamic Optimization of Slow Freezing Processes for Human Induced Pluripotent Stem Cells by Modeling Intracontainer Condition2020

    • Author(s)
      Hayashi Yusuke, Horiguchi Ikki, Kino-oka Masahiro, Sugiyama Hirokazu
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 48 Pages: 265-270

    • DOI

      10.1016/b978-0-12-823377-1.50045-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Journal Article] Online decision-support tool "TECHoice" for the equipment technology choice in sterile filling processes of biopharmaceuticals2019

    • Author(s)
      Haruku Shirahata, Sara Badr, Yuki Shinno, Shuta Hagimori, Hirokazu Sugiyama
    • Journal Title

      Processes

      Volume: 7 Issue: 7 Pages: 448-448

    • DOI

      10.3390/pr7070448

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
  • [Journal Article] Pharma PSE Research at The University of Tokyo2019

    • Author(s)
      Hirokazu Sugiyama
    • Journal Title

      PD2M Newsletter

      Volume: 2 Pages: 1-1

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Relevance of regulatory constraints in designing pharmaceutical manufacturing processes: A case study on waste solvent recovery2019

    • Author(s)
      Sugiyama Hirokazu、Morikawa Yusuke、Matsuura Mai、Xu Menghe
    • Journal Title

      Sustainable Production and Consumption

      Volume: 17 Pages: 136-147

    • DOI

      10.1016/j.spc.2018.09.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第9回: バイオ医薬品無菌充填工程を対象とするオンライン技術選択支援ツール"TECHoice"2019

    • Author(s)
      白畑 春来, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 35 Pages: 2605-2610

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Data mining algorithm for pre-processing biopharmaceutical drug product manufacturing records2019

    • Author(s)
      Casola Gioele、Siegmund Christian、Mattern Markus、Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 124 Pages: 253-269

    • DOI

      10.1016/j.compchemeng.2018.12.001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Integrated white-box models for designing freezing processes of human induced pluripotent stem cells considering diversity within a container2019

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 46 Pages: 877-882

    • DOI

      10.1016/b978-0-12-818634-3.50147-8

    • ISBN
      9780128186343
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation2019

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
    • Journal Title

      Computers and Chemical Engineering

      Volume: 132 Pages: 106597-106597

    • DOI

      10.1016/j.compchemeng.2019.106597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] A distribution-based approach for determining lot sizes in the filling of human-induced pluripotent stem cells2019

    • Author(s)
      Hirokazu Sugiyama, Masaki Shiokaramatsu, Masahiro Kino-oka
    • Journal Title

      Regenerative Therapy

      Volume: 12 Pages: 94-101

    • DOI

      10.1016/j.reth.2019.04.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Dynamic modelling and simulation of Chinese hamster ovary (CHO) cell fermentation for advanced biopharmaceutical manufacturing2019

    • Author(s)
      Haruku Shirahata, Samir Diab, Hirokazu Sugiyama, Dimitrios I. Gerogiorgi
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 46 Pages: 673-678

    • DOI

      10.1016/b978-0-12-818634-3.50113-2

    • ISBN
      9780128186343
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
  • [Journal Article] Pharma PSE Spotlight 第7回: バイオ医薬品無菌充填におけるシングルユース・マルチユース技術の多目的選択支援ツール2019

    • Author(s)
      白畑 春来, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 35 Pages: 377-383

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第10回:容器内ばらつきのモデル化によるヒトiPS細胞の緩慢凍結プロセス設計2019

    • Author(s)
      林 勇佑, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 35 Pages: 2965-2968

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Alternative generation and multiobjective evaluation using a design framework: Case study on sterile filling processes of biopharmaceuticals2019

    • Author(s)
      Shirahata Haruku、Badr Sara、Dakessian Shant、Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 123 Pages: 286-299

    • DOI

      10.1016/j.compchemeng.2018.12.019

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
  • [Journal Article] Multiobjective decision-support tools for the choice between single-use and multi-use technologies in sterile filling of biopharmaceuticals2019

    • Author(s)
      Shirahata Haruku、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      Computers & Chemical Engineering

      Volume: 122 Pages: 114-128

    • DOI

      10.1016/j.compchemeng.2018.06.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
  • [Journal Article] Dynamic modelling, simulation and economic evaluation of two CHO cell-based production modes towards developing biopharmaceutical manufacturing processes2019

    • Author(s)
      Haruku Shirahata, Samir Diab, Hirokazu Sugiyama, Dimitrios I. Gerogiorgis
    • Journal Title

      Chemical Engineering Research and Design

      Volume: 150 Pages: 218-233

    • DOI

      10.1016/j.cherd.2019.07.016

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
  • [Journal Article] A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide2019

    • Author(s)
      Matsunami Kensaku、Nagato Takuya、Hasegawa Koji、Sugiyama Hirokazu
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 559 Pages: 210-219

    • DOI

      10.1016/j.ijpharm.2019.01.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
  • [Journal Article] Pharma PSE Spotlight 第11回:経済性評価に基づく注射剤製造プロセスのロットサイズ決定2019

    • Author(s)
      山田 真弘, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 36 Pages: 871-875

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第8回: エテンザミドを用いた医薬品錠剤製造におけるバッチ・連続技術の大スケール実験的検討2019

    • Author(s)
      松並 研作, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 35 Pages: 1533-1537

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Approach for Multicriteria Equipment Redesign in Sterile Manufacturing of Biopharmaceuticals2018

    • Author(s)
      Zeberli Anicia、Casola Gioele、Badr Sara、Siegmund Christian、Mattern Markus、Sugiyama Hirokazu
    • Journal Title

      Journal of Pharmaceutical Innovation

      Volume: in press Issue: 1 Pages: 15-25

    • DOI

      10.1007/s12247-018-9355-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Decision Support Method for the Choice between Batch and Continuous Technologies in Solid Drug Product Manufacturing2018

    • Author(s)
      Matsunami Kensaku、Miyano Takuya、Arai Hiroaki、Nakagawa Hiroshi、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      Industrial & Engineering Chemistry Research

      Volume: 57 Issue: 30 Pages: 9798-9809

    • DOI

      10.1021/acs.iecr.7b05230

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
  • [Journal Article] Models for Designing Hydrogen Peroxide Decontamination Processes in Sterile Drug Product Manufacturing2018

    • Author(s)
      Yabuta Keisho、Futamura Haruka、Kawasaki Koji、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      Computer Aided Process Engineering

      Volume: 43 Pages: 1613-1618

    • DOI

      10.1016/b978-0-444-64235-6.50281-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第5回: 無菌製剤製造における収率向上のためのプロセスモデル2018

    • Author(s)
      藪田 啓奨, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 34 Pages: 1329-1334

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Design-oriented regression models for H 2 O 2 decontamination processes in sterile drug product manufacturing considering rapidity and sterility2018

    • Author(s)
      Yabuta Keisho、Futamura Haruka、Kawasaki Koji、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 548 Issue: 1 Pages: 466-473

    • DOI

      10.1016/j.ijpharm.2018.06.055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Quantitative Analysis on the Relevance of Regulatory Constraints in Designing Pharmaceutical Manufacturing Processes2018

    • Author(s)
      Sugiyama Hirokazu、Morikawa Yusuke、Matsuura Mai、Xu Menghe
    • Journal Title

      Computer Aided Process Engineering

      Volume: 44 Pages: 2119-2124

    • DOI

      10.1016/b978-0-444-64241-7.50348-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第4回: 注射剤製造における賦形剤使用プロセスの多目的設計手法2018

    • Author(s)
      杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 34 Pages: 300-304

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Industrial Scale Experiments towards the Development of Process Evaluation Models for Continuous Pharmaceutical Tablet Manufacturing2018

    • Author(s)
      Matsunami Kensaku、Nagato Takuya、Hasegawa Koji、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      Computer Aided Process Engineering

      Volume: 43 Pages: 1655-1660

    • DOI

      10.1016/b978-0-444-64235-6.50288-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
  • [Journal Article] Data mining-based algorithm for pre-processing biopharmaceutical manufacturing records2018

    • Author(s)
      Casola Gioele、Siegmund Christian、Mattern Markus、Sugiyama Hirokazu
    • Journal Title

      Computer Aided Process Engineering

      Volume: 44 Pages: 2263-2268

    • DOI

      10.1016/b978-0-444-64241-7.50372-4

    • ISBN
      9780444642417
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Multilayer and Multiobjective Design Platform for Drug Product Manufacturing Processes of Biopharmaceuticals2018

    • Author(s)
      Shirahata Haruku、Dakessian Shant、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      Computer Aided Process Engineering

      Volume: 44 Pages: 301-306

    • DOI

      10.1016/b978-0-444-64241-7.50045-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
  • [Journal Article] 製剤と粒子設計: 意思決定の切り口からみた製剤の連続生産2018

    • Author(s)
      杉山 弘和, 松並 研作
    • Journal Title

      Pharm Tech Japan

      Volume: 34 Pages: 2261-2265

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第6回: 過酸化水素除染プロセスの多目的設計に向けた統計モデル2018

    • Author(s)
      藪田 啓奨, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 34 Pages: 2941-2946

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Economic Evaluation of Batch and Continuous Manufacturing Technologies for Solid Drug Products during Clinical Development2018

    • Author(s)
      Matsunami Kensaku、Tanabe Shuichi、Nakagawa Hiroshi、Hirao Masahiko、Sugiyama Hirokazu
    • Journal Title

      Computer Aided Process Engineering

      Volume: 44 Pages: 2131-2136

    • DOI

      10.1016/b978-0-444-64241-7.50350-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
  • [Journal Article] Uncertainty-conscious Methodology for Process Performance Assessment in Biopharmaceutical Drug Product Manufacturing2017

    • Author(s)
      Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Journal Title

      AIChE Journal

      Volume: 64 Issue: 4 Pages: 1272-1284

    • DOI

      10.1002/aic.16020

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第3回: ISPE日本本部 Pharma PSE COPの紹介2017

    • Author(s)
      杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 33 Pages: 2911-2916

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Pharma PSE Spotlight 第1回:無菌製剤製造における製品ロス低減のための計画手法2017

    • Author(s)
      杉山 弘和, 伊藤 正晃
    • Journal Title

      Pharm Tech Japan

      Volume: 33 Pages: 975-979

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Innovative approach for identifying root causes of glass defects in sterile drug product manufacturing2017

    • Author(s)
      Lukas Eberle, Alexander Svensson, Andreas Graser, Joerg Luemkemann, Hirokazu Sugiyama, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      European Journal of Pharmaceutical Sciences

      Volume: 104 Pages: 162-170

    • DOI

      10.1016/j.ejps.2017.03.015

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Pharma PSE Spotlight 第2回: 注射剤製造におけるシングルユース・マルチユース技術の選択支援手法2017

    • Author(s)
      白畑 春来, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 33 Pages: 1529-1535

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Integrated Process Performance Assessment Considering Uncertainty in Biopharmaceutical Manufacturing Operations2017

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 40 Pages: 2227-2232

    • DOI

      10.1016/b978-0-444-63965-3.50373-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Decision-support method for the choice between single-use and multi-use technologies in sterile drug product manufacturing2017

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Journal of Pharmaceutical Innovation

      Volume: 12 Issue: 1 Pages: 1-13

    • DOI

      10.1007/s12247-016-9264-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] 連続生産を対象とするプロセスシステム工学研究2017

    • Author(s)
      松並 研作, 杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 33 Pages: 2619-2625

    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Process Systems Engineering Approaches for Drug Product Manufacturing: from Tablets to Injectables2017

    • Author(s)
      Hirokazu Sugiyama, Kensaku Matsunami, Keisho Yabuta
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 40 Pages: 2785-2790

    • DOI

      10.1016/b978-0-444-63965-3.50466-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Process model for enhancing yield in sterile drug product manufacturing2017

    • Author(s)
      Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Journal of Pharmaceutical Innovation

      Volume: accepted for publication Issue: 3 Pages: 194-205

    • DOI

      10.1007/s12247-017-9278-9

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Risk Evaluation Models for the Design of Parenterals Manufacturing Processes2017

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 40 Pages: 2791-2796

    • DOI

      10.1016/b978-0-444-63965-3.50467-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Journal Article] Product loss reduction in batch manufacturing of sterile drug products2016

    • Author(s)
      Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Design method for pharmaceutical tablet production considering batch & continuous technologies2016

    • Author(s)
      Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] 製薬プロセスシステム工学Pharma PSEの開拓2016

    • Author(s)
      杉山 弘和
    • Journal Title

      Pharm Tech Japan

      Volume: 32 Pages: 2421-2426

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Multiobjective retrofitting methodology for manufacturing processes of active pharmaceutical ingredients considering environmental, health and safety risks2016

    • Author(s)
      Hirokazu Sugiyama, Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao
    • Journal Title

      Computer Aided Chemical Engineering (Proceedings of 26th European Symposium on Computer Aided Process Engineering)

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Rigorous approach to scheduling of sterile drug product manufacturing2016

    • Author(s)
      Lukas Gallus Eberle, Elisabet Capon Carcia, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      Computers and Chemical Engineering

      Volume: 87 Pages: 82-89

    • DOI

      10.1016/j.compchemeng.2016.07.028

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Design method for pharmaceutical tablet production considering batch & continuous technologies2016

    • Author(s)
      Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] 医薬品製造を対象とするプロセスシステム工学の最新動向2016

    • Author(s)
      杉山 弘和
    • Journal Title

      化学工学

      Volume: 80 Pages: 450-450

    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Data-driven tiered procedure for enhancing yield in drug product manufacturing2016

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      Computers and Chemical Engineering

      Volume: 87 Pages: 82-89

    • DOI

      10.1016/j.compchemeng.2015.12.012

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Hybrid approach for improving drug product manufacturing efficiency2016

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Product loss reduction in batch manufacturing of sterile drug products2016

    • Author(s)
      Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Mid-term scheduling model based on state-task-network considering plant specific constraints in pharmaceutical manufacturing2016

    • Author(s)
      Gioele Casola, Lukas Gallus Eberle, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Journal Title

      Computer Aided Chemical Engineering (Proceedings of 26th European Symposium on Computer Aided Process Engineering)

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] 医薬品製造を対象とするモデル化・シミュレーション・最適化研究2016

    • Author(s)
      杉山 弘和
    • Journal Title

      クリーンテクノロジー

      Volume: 26 Pages: 65-68

    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Process model of sterile drug product manufacturing for yield enhancement2016

    • Author(s)
      Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Conducting process systems engineering research on pharmaceutical Mmnufacturing2016

    • Author(s)
      Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)

      Volume: N/A

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Multiobjective retrofitting methodology for manufacturing processes of active pharmaceutical ingredients considering environmental, health and safety risks2016

    • Author(s)
      Hirokazu Sugiyama, Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 38 Pages: 79-84

    • DOI

      10.1016/b978-0-444-63428-3.50018-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Method for reducing environmental, health, and safety risks in active pharmaceutical ingredient manufacturing based on multiobjective evaluation2016

    • Author(s)
      Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Process Safety and Environmental Protection

      Volume: 104 Pages: 304-313

    • DOI

      10.1016/j.psep.2016.09.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Mid-term scheduling model based on state-task-network considering plant specific constraints in pharmaceutical manufacturing2016

    • Author(s)
      Gioele Casola, Lukas Gallus Eberle, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 38 Pages: 1141-1146

    • DOI

      10.1016/b978-0-444-63428-3.50195-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Conducting process systems engineering research on pharmaceutical manufacturing2016

    • Author(s)
      Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Process model of sterile drug product manufacturing for yield enhancement2016

    • Author(s)
      Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Hybrid approach for improving drug product manufacturing efficiency2016

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Optimal scheduling of liquid drug product manufacturing2015

    • Author(s)
      Lukas Gallus Eberle, Elisabet Capón-Garcia, Martin Senninger, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      Computer Aided Chemical Engineering

      Volume: 36 Pages: 2033-2038

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Planning Method for Reducing Product Losses in Manufacturing Sterile Drug Products2015

    • Author(s)
      Hirokazu Sugiyama, Masaaki Ito, Masahiko Hirao
    • Journal Title

      Journal of Chemical Engineering of Japan

      Volume: ?

    • NAID

      130005104386

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Systematic retrofitting methodology for recrystallization of thermally unstable active pharmaceutical ingredients2015

    • Author(s)
      Gioele Casola, Hirokazu Sugiyama, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao
    • Journal Title

      Computer Aided Chemical Engineering (Proceedings of 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering)

      Volume: 36 Pages: 2171-2176

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Process-based method for reducing product losses in pharmaceutical manufacturing2015

    • Author(s)
      Hirokazu Sugiyama, Masaaki Ito, Masahiko Hirao
    • Journal Title

      Computer Aided Chemical Engineering (Proceedings of 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering)

      Volume: 36 Pages: 2189-2194

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] 医薬品製造プロセスの多目的設計2015

    • Author(s)
      杉山 弘和
    • Journal Title

      化学工業

      Volume: 66 Pages: 952-958

    • NAID

      40020659171

    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Improving pharmaceutical batch production processes with data-based tiered approach2015

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      Computer Aided Chemical Engineering (Proceedings of 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering)

      Volume: 36 Pages: 1967-1972

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] 医薬品製造を対象とする新しいプロセスシステム工学「Pharma PSE」2015

    • Author(s)
      杉山 弘和
    • Journal Title

      化学工学会バイオ部会ニュースレター

      Volume: 40 Pages: 3-6

    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Systematic retrofitting methodology for pharmaceutical drug purification processes2015

    • Author(s)
      Gioele Casola, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
    • Journal Title

      Computers and Chemical Engineering

      Volume: 88 Pages: 177-188

    • DOI

      10.1016/j.compchemeng.2015.05.024

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Multiobjective design method for the use processes of pharmaceutical excipients considering quality and cost-effectiveness2015

    • Author(s)
      Takayuki Iida, Kosuke Ota, Tomohito Sasozaki, Hirokazu Sugiyama
    • Journal Title

      Journal of Pharmaceutical Innovation

      Volume: 10 Issue: 4 Pages: 313-323

    • DOI

      10.1007/s12247-015-9228-3

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26820343, KAKENHI-PROJECT-15J07161
  • [Journal Article] Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes2014

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Journal Title

      24th European Symposium on Computer Aided Process Engineering

      Volume: A Pages: 463-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Reducing Energy Consumption in Pharmaceutical Production Processes: Framework and Case Study2014

    • Author(s)
      Georg Mueller, Hirokazu Sugiyama, Simon Stocker, Rainer Schmidt
    • Journal Title

      Journal of Pharmaceutical Innovation

      Volume: 9 Issue: 3 Pages: 212-216

    • DOI

      10.1007/s12247-014-9188-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Integration Framework for Improving Quality and Cost-Effectiveness in Pharmaceutical Production Processes2014

    • Author(s)
      Sugiyama, H., Hirao, M.
    • Journal Title

      24th European Symposium on Computer Aided Process Engineering

      Volume: in print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Journal Article] Design of recycling system for poly(methyl methacrylate) (PMMA). Part 2 : process hazards and material flow analysis2014

    • Author(s)
      Y. Kikuchi, M. Hirao, H. Sugiyama, S. Papadokonstantakis, K.Hungerbuehler, T. Ookubo, A. Sasaki
    • Journal Title

      Int. J. LCA

      Volume: 19 Issue: 2 Pages: 307-319

    • DOI

      10.1007/s11367-013-0625-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23360404, KAKENHI-PROJECT-24246150
  • [Journal Article] Business Process Model of Continuous Improvement in Pharmaceutical Manufacturing2014

    • Author(s)
      杉山 弘和、シュミット ライナー
    • Journal Title

      KAGAKU KOGAKU RONBUNSHU

      Volume: 40 Issue: 3 Pages: 201-210

    • DOI

      10.1252/kakoronbunshu.40.201

    • NAID

      130004855782

    • ISSN
      0386-216X, 1349-9203
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Journal Article] Integration Framework for Improving Quality and Cost-Effectiveness in Pharmaceutical Production Processes2014

    • Author(s)
      Hirokazu Sugiyama, Masahiko Hirao
    • Journal Title

      24th European Symposium on Computer Aided Process Engineering

      Volume: A Pages: 379-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Improving Lead Time of Pharmaceutical Production Processes Using Monte Carlo Simulation2014

    • Author(s)
      Eberle, L., Sugiyama, H., Schmidt, R.
    • Journal Title

      Computers & Chemical Engineering

      Volume: accepted

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Journal Article] Improving Lead Time of Pharmaceutical Production Processes Using Monte Carlo Simulation2014

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Rainer Schmidt
    • Journal Title

      Computers and Chemical Engineering

      Volume: 68 Pages: 255-263

    • DOI

      10.1016/j.compchemeng.2014.05.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Journal Article] Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes2014

    • Author(s)
      Eberle, L., Sugiyama, H., Papadokonstantakis, S., Graser, A., Schmidt, R., Hungerbuehler, K.
    • Journal Title

      Proceedings of 24th European Symposium on Computer Aided Process Engineering

      Volume: in print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Patent] 情報提供装置及びプログラム2018

    • Inventor(s)
      杉山 弘和, 白畑 春来, ツルヒャー フィリップ サミュエル
    • Industrial Property Rights Holder
      杉山 弘和, 白畑 春来, ツルヒャー フィリップ サミュエル
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-163033
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] プロセスとして見た錠剤連続生産2023

    • Author(s)
      杉山弘和
    • Organizer
      粉体工学会第58回夏期シンポジウム
    • Data Source
      KAKENHI-PROJECT-21H01704
  • [Presentation] 供給安定性を考慮した医薬品添加剤の選択支援手法2023

    • Author(s)
      根本 耕輔, 林 勇佑, 杉山 弘和
    • Organizer
      化学工学会 第88年会
    • Data Source
      KAKENHI-PROJECT-23K21057
  • [Presentation] 固形製剤連続生産 プロセスシステム工学の視点から2023

    • Author(s)
      杉山弘和
    • Organizer
      立命館大学創剤・製剤技術研究コンソーシアム 第3回研究会
    • Data Source
      KAKENHI-PROJECT-21H01704
  • [Presentation] CFDシミュレーションを用いたヒトiPS細胞の連続凍結プロセス設計2023

    • Author(s)
      林 勇佑, Scholz Benedikt, 杉山 弘和
    • Organizer
      化学工学会 第88年会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] A hybrid-model-based approach to continuous freezing process design for human induced pluripotent stem cells2022

    • Author(s)
      Yusuke Hayashi, Hirokazu Sugiyama
    • Organizer
      10th Asian Symposium on Process Systems Engineering
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] コンパニオン診断の費用対効果モデリングと分析2022

    • Author(s)
      岡村 梢, 濵田 梨渚, 土屋 裕輝, 太田 誠一, 杉山 弘和
    • Organizer
      化学工学会第87年会
    • Data Source
      KAKENHI-PROJECT-23K21057
  • [Presentation] Pharma PSE:医薬品製造を"reimagine"するマルチスケール・アプローチ2022

    • Author(s)
      杉山 弘和
    • Organizer
      2022年 ISPE日本本部 年次大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] 感染症数理モデルを用いたCOVID-19のワクチン供給シナリオ分析2022

    • Author(s)
      市田 侑亮, 松並 研作, Kim Junu, 岡村 梢, Badr Sara, 杉山 弘和
    • Organizer
      化学工学会第87年会
    • Data Source
      KAKENHI-PROJECT-23K21057
  • [Presentation] Framework for designing solid drug product manufacturing processes based on economic and quality assessment2022

    • Author(s)
      Kensaku Matsunami, Sara Badr, Hirokazu Sugiyama
    • Organizer
      The 14th International Symposium on Process Systems Engineering (PSE 2021+)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H01704
  • [Presentation] Role of physical, statistical, and hybrid modelling approaches for pharmaceutical manufacturing2022

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      10th Asian Symposium on Process Systems Engineering
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] ヒトiPS細胞凍結プロセスにおけるトンネルフリーザーの適用2022

    • Author(s)
      林 勇佑, 杉山 弘和
    • Organizer
      化学工学会 第53回秋季大会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] コンパニオン診断の費用対効果分析のためのモデリング・アプローチ2022

    • Author(s)
      岡村 梢, 太田 誠一, 杉山 弘和
    • Organizer
      化学工学会 第53回秋季大会
    • Data Source
      KAKENHI-PROJECT-23K21057
  • [Presentation] ヒトiPS細胞向け凍結保存プロセスのマルチスケール設計2022

    • Author(s)
      林 勇佑、杉山 弘和
    • Organizer
      化学工学会第87年会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] ヒトiPS細胞に対する連続凍結プロセスの適用2022

    • Author(s)
      林 勇佑, 杉山 弘和
    • Organizer
      第65回 自動制御連合講演会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] An agent-based model for cost-effectiveness analysis in the manufacture of allogeneic human induced pluripotent cells in Japan2022

    • Author(s)
      Yusuke Hayashi, Kota Oishi, Hirokazu Sugiyama
    • Organizer
      The 14th International Symposium on Process Systems Engineering
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] エージェントベーストモデルを用いた他家iPS細胞治療の費用対効果分析2021

    • Author(s)
      林 勇佑, 大石 宏太, 杉山 弘和
    • Organizer
      化学工学会第86年会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] ハイブリッドモデルを用いたヒトiPS細胞の充填・凍結・解凍プロセス設計2021

    • Author(s)
      林 勇佑、紀ノ岡 正博、杉山 弘和
    • Organizer
      化学工学会第52回秋季大会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] Model-Based Assessment of Freezing Temperature Profiles for Human Induced Pluripotent Stem Cells2021

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-Oka, Hirokazu Sugiyama
    • Organizer
      2020 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] 数値流体力学シミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討2021

    • Author(s)
      林 勇佑, Scholz Benedikt, 杉山 弘和
    • Organizer
      第20回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] 連続生産を考慮した製法選択 Selection of production methods considering continuous manufacturing2020

    • Author(s)
      杉山 弘和
    • Organizer
      連続生産の実現・推進を考える会 特別講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Multiobjective dynamic optimization of slow freezing processes for human induced pluripotent stem cells by modeling intracontainer condition2020

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-Oka, Hirokazu Sugiyama
    • Organizer
      The 30th European Symposium on Computer-Aided Process Engineering (ESCAPE-30)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] 医薬品製造プロセスにおけるAI活用2020

    • Author(s)
      杉山 弘和
    • Organizer
      AI・IoT・ビッグデータ活用の基礎とプロセスへの実装
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 原薬製造におけるバッチ・フロー合成の選択支援手法2020

    • Author(s)
      金 俊佑, 米倉 寛智, 渡邊 健朗, 吉川 覚, 中西 勇夫, 杉山 弘和
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 連続・バッチ方式を考慮した注射剤製造プロセスの設計手法2020

    • Author(s)
      山田 真弘, 吉岡 泰之, 中西 勇夫, 杉山 弘和
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] ヒトiPS細胞の緩慢凍結における温度プロファイルの最適化シミュレーション2020

    • Author(s)
      林 勇佑, 堀口 一樹, 紀ノ岡 正博, 杉山 弘和
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] プロセスの視点から見た過酸化水素除染:迅速性と連続性2020

    • Author(s)
      杉山 弘和
    • Organizer
      第8回 最新の医薬、再生医療に関するGMP、技術動向を考える会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Quantum chemistry and molecular dynamics simulations on cryoprotective agents for human stem cells2020

    • Author(s)
      Yusuke Hayashi, Yuka Nakajima, Hirokazu Sugiyama
    • Organizer
      The 9th Asian Symposium on Process Systems Engineering (9th PSE Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] CFDシミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討2020

    • Author(s)
      林 勇佑, Scholz Benedikt, 杉山 弘和
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 無菌製剤製造における過酸化水素除染プロセスのモデルベースト設計2020

    • Author(s)
      藪田 啓奨, 二村 はるか, 川崎 康司, 杉山 弘和
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Model-based design of freezing temperature profile for human induced pluripotent stem cells2020

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
    • Organizer
      The 57th Annual Meeting of the Society for Cryobiology (CRYO2020)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 数値流体力学シミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討2020

    • Author(s)
      林 勇佑, Scholz Benedikt, 杉山 弘和
    • Organizer
      第20回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Multiobjective dynamic optimization of slow freezing processes for human induced pluripotent stem cells by modeling intracontainer condition2020

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-Oka, Hirokazu Sugiyama
    • Organizer
      The 30th European Symposium on Computer-Aided Process Engineering (ESCAPE-30)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Analysis of the effects of process parameters on start-up operation in continuous wet granulation2020

    • Author(s)
      Matsunami Kensaku, Nopens Ingmar, Sugiyama Hirokazu, De Beer Thomas
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] シングルユース技術・連続生産を考慮したバイオ医薬品製造プロセスの俯瞰的設計2020

    • Author(s)
      白畑 春来, Badr Sara, 杉山 弘和
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] ヒトiPS細胞の緩慢凍結における温度プロファイルの最適化シミュレーション2020

    • Author(s)
      林 勇佑, 堀口 一樹, 紀ノ岡 正博, 杉山 弘和
    • Organizer
      化学工学会 第51回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] ヒトiPS細胞の緩慢凍結における温度プロファイルの最適化シミュレーション2020

    • Author(s)
      林 勇佑, 堀口 一樹, 紀ノ岡 正博, 杉山 弘和
    • Organizer
      化学工学会 第51回秋季大会
    • Data Source
      KAKENHI-PROJECT-20K21102
  • [Presentation] Holistic and model-based design of oral drug manufacturing processes considering uncertainty in clinical development2019

    • Author(s)
      Kensaku Matsunami, Hirokazu Sugiyama
    • Organizer
      The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Economic evaluation tool for holistic design of solid drug product manufacturing processes considering continuous technology2019

    • Author(s)
      Kensaku Matsunami, Fabian Sternal, Keita Yaginuma, Shuichi Tanabe, Hiroshi Nakagawa, Hirokazu Sugiyama
    • Organizer
      2019 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Model-based determination of lot-size in pharmaceutical injectable manufacturing2019

    • Author(s)
      Masahiro Yamada, Sara Badr, Shouko Fukuda, Manabu Nakaya, Yasuyuki Yoshioka, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] バイオ医薬品注射剤製造における装置技術選択のためのオンライン支援ツール2019

    • Author(s)
      白畑 春来, 新納 裕樹, 萩森 秀太, Badr Sara, 杉山 弘和
    • Organizer
      化学工学会 第84年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 製剤製造を対象とする多目的かつ実践的なプロセス設計手法の開発2019

    • Author(s)
      杉山 弘和
    • Organizer
      第17回技術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Simulation-based design of slow freezing processes for human induced pluripotent stem cells considering intracontainer variation2019

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
    • Organizer
      18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Alternative generation and evaluation using a design framework: Case study on drug substance manufacturing processes of biopharmaceuticals2019

    • Author(s)
      Haruku Shirahata, Sara Badr, Hirokazu Sugiyama
    • Organizer
      2019 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 連続生産とプロセス設計2019

    • Author(s)
      杉山 弘和
    • Organizer
      第9回レギュラトリーサイエンス学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Data-driven predictive monitoring and operation support for change-over processes in biopharmaceutical drug product manufacturing2019

    • Author(s)
      Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      2019 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation2019

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
    • Organizer
      2019 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Roles of process systems engineering in the design and operation of pharmaceutical manufacturing processes2019

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Dynamic modelling and simulation of Chinese hamster ovary (CHO) cell fermentation for advanced biopharmaceutical manufacturing2019

    • Author(s)
      Haruku Shirahata, Samir Diab, Hirokazu Sugiyama, Dimitrios Gerogiorgis
    • Organizer
      The 29th European Symposium on Computer-Aided Process Engineering (ESCAPE-29)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Process Systems Engineering for Pharmaceutical Process Design and Operation2019

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      3rd International Conference on Functional Materials and Chemical Engineering (ICFMCE-2019)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 連続生産を考慮した固形製剤製造プロセスの経済性評価2019

    • Author(s)
      松並 研作, 田邉 修一, 柳沼 啓太, 杉山 弘和
    • Organizer
      化学工学会 第84年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 製薬プロセスシステム工学と意思決定支援2019

    • Author(s)
      杉山 弘和
    • Organizer
      インターフェックスジャパン セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Machine learning applications for predictive operation support in change-over processes of biopharmaceutical drug product manufacturing2019

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Continuous Manufacturing from Decision-Making Perspective2019

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      2019 ISPE Asia Pacific Pharmaceutical Manufacturing Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Freeze-thaw process design of induced pluripotent stem cells using white-box models2019

    • Author(s)
      Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      The 29th European Symposium on Computer-Aided Process Engineering (ESCAPE-29)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Simultaneous design of process and scheduling for pharmaceutical decontamination2019

    • Author(s)
      Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Hirokazu Sugiyama
    • Organizer
      18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Data-driven predictive monitoring and operation support for decontamination processes in biopharmaceutical manufacturing2018

    • Author(s)
      Zeberli Anicia, Badr Sara, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      化学工学会 第50回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Data mining-based algorithm for pre-processing biopharmaceutical manufacturing records2018

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      13th International Symposium on Process Systems Engineering (PSE 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] バイオ医薬品製造における技術選択のオンライン支援ツール2018

    • Author(s)
      白畑春来, 新納裕樹, 萩森秀太, Rizki Darmawan, Sara Badr, 杉山弘和
    • Organizer
      MATLAB EXPO 2018 Japan
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Industrial scale experiments towards the development of process evaluation models for continuous pharmaceutical tablet manufacturing2018

    • Author(s)
      Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      28th European Symposium on Computer Aided Process Engineering (ESCAPE-28)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Economic evaluation of batch and continuous manufacturing technologies for solid drug products during clinical development2018

    • Author(s)
      Kensaku Matsunami, Shuichi Tanabe, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      13th International Symposium on Process Systems Engineering (PSE 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Data-driven real-time operation support for decontamination processes in biopharmaceutical drug product manufacturing2018

    • Author(s)
      Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      2018 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品製造におけるシステムズ・アプローチの役割2018

    • Author(s)
      杉山 弘和
    • Organizer
      医療薬学フォーラム2018・第26回クリニカルファーマシーシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] ライフサイクルを考慮したリチウムイオン電池の安全設計支援手法2018

    • Author(s)
      山西 智紀, 天沢 逸里, 杉山 弘和, 平尾 雅彦
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-15K12469
  • [Presentation] プロセス情報の統合利用による注射剤製造のロットサイズ決定2018

    • Author(s)
      山田 真弘, Badr Sara, 福田 咲香, 中家 学, 吉岡 泰之, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会 第50回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] バイオ医薬品注射剤製造におけるシングルユース・マルチユース技術の選択支援モデル2018

    • Author(s)
      杉山 弘和, 白畑 春来, Zuercher Philipp, Badr Sara
    • Organizer
      化学工学会 第50回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Process systems engineering for pharmaceutical manufacturing2018

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      KIChE-SCEJ Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品製造のためのプロセスシステム工学2018

    • Author(s)
      杉山 弘和
    • Organizer
      第7回医薬品製造に関する技術動向を考える会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Process modelling, simulation and optimisation for continuous biopharmaceutical manufacturing2018

    • Author(s)
      Samir Diab, Haruku Shirahata, Hirokazu Sugiyama, Dimitrios I. Gerogiorgis
    • Organizer
      2018 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Framework for data-driven process improvement and operations support in biopharmaceutical drug product manufacturing2018

    • Author(s)
      Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      化学工学会 第50回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Multi-stage and multi-objective design tool for process design in sterile filling of biopharmaceuticals2018

    • Author(s)
      Haruku Shirahata, Philipp Zuercher, Sara Badr, Hirokazu Sugiyama
    • Organizer
      2018 AIChE Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] バイオ医薬品の製造プロセス設計における意思決定支援2018

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会関東支部 バイオプロセス講演・見学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Quantitative analysis on the relevance of regulatory constraints in designing pharmaceutical manufacturing processes2018

    • Author(s)
      Hirokazu Sugiyama, Yusuke Morikawa, Mai Matsuura, Menghe Xu
    • Organizer
      13th International Symposium on Process Systems Engineering (PSE 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 実験計画法に基づく錠剤連続製造のプロセス評価モデル2018

    • Author(s)
      松並 研作, 長門 琢也, 長谷川 浩司, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会 第50回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Models for designing hydrogen peroxide decontamination processes in sterile drug product manufacturing2018

    • Author(s)
      Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      28th European Symposium on Computer Aided Process Engineering (ESCAPE-28)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 意思決定の切り口から見た連続生産2018

    • Author(s)
      杉山 弘和
    • Organizer
      ISPE日本本部 第17回冬季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] バイオ医薬品の製造プロセス設計における意思決定支援-品質と効率の両立-2018

    • Author(s)
      杉山 弘和
    • Organizer
      国立医薬品食品衛生研究所特別講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Multilayer and multiobjective design platform for drug product manufacturing processes of biopharmaceuticals2018

    • Author(s)
      Haruku Shirahata, Shant Dakessian, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      13th International Symposium on Process Systems Engineering (PSE 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 製薬プロセスシステム工学の最近の進捗2018

    • Author(s)
      杉山 弘和
    • Organizer
      大阪大学細胞製造コトづくり講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品錠剤のバッチ・連続製造プロセスにおける製品品質評価2017

    • Author(s)
      松並 研作, 長門 琢也, 長谷川 浩司, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第49回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品製剤製造プロセスにおけるマテリアルロス低減手法2017

    • Author(s)
      伊藤 正晃, 秋本 泰明, 高橋 健二, 加藤 義和, 菊地 宣昭, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 経済性評価に基づく注射剤製造プロセスのロットサイズ決定手法2017

    • Author(s)
      山田 真弘, 吉岡 泰之, 中家 学, 福田 咲香, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 製剤製造における装置技術情報を統合したプロセス合成2017

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会第49回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品製造におけるモデルベースト設計の役割2017

    • Author(s)
      杉山 弘和
    • Organizer
      2017年ISPE日本本部年次大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品・再生医療製品の製造におけるモデルベースト設計2017

    • Author(s)
      杉山 弘和
    • Organizer
      第16回日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品製造の課題とプロセスシステム工学による解決のアプローチ2017

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会開発型企業の会 2017年度第2回技術交流会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 臨床開発時における固形製剤製造プロセスの設計手法2017

    • Author(s)
      松並 研作, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Monte Carlo シミュレーションを用いた他家iPS細胞のワーキングセルバンク設計2017

    • Author(s)
      塩唐松 正樹, 紀ノ岡 正博, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 連続製造を対象とするプロセスシステム工学研究2017

    • Author(s)
      杉山 弘和
    • Organizer
      第25回静岡フォーラム・第50回研究交流セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] プロセス特性を考慮した原薬製造における環境・健康・安全リスク低減手法2017

    • Author(s)
      福原 祥平, 西舘 修, 菊地 真, 高橋 美文, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Big data-platform for supporting design and operation of biopharmaceutical decontamination processes2017

    • Author(s)
      Zeberli Anicia, Roedl Thomas, Knueppel Stephanie, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Risk evaluation models for the design of parenterals manufacturing processes2017

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      The 27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Application of computational fluid dynamics for equipment redesign in sterile manufacturing of biopharmaceuticals2017

    • Author(s)
      Zeberli Anicia, Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] アクティビティモデリング手法IDEF0の基礎2017

    • Author(s)
      杉山 弘和
    • Organizer
      産業技術総合研究所福島再生可能エネルギー研究所 セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Decision-support tools for biopharmaceutical manufacturing2017

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      化学工学会第83年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 電気自動車用リチウムイオン電池のリユース及びリサイクルにおける技術選択支援2017

    • Author(s)
      阿部将宜、杉山弘和、平尾雅彦
    • Organizer
      第12回日本LCA学会研究発表会
    • Place of Presentation
      産業技術総合研究所つくばセンター(茨城県つくば市)
    • Year and Date
      2017-03-01
    • Data Source
      KAKENHI-PROJECT-15K12469
  • [Presentation] シングルユース・マルチユース技術の選択を考慮した注射剤製造プロセスの設計手法2017

    • Author(s)
      白畑 春来, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Data-driven approaches for process improvement and operation support in biopharmaceutical drug product manufacturing2017

    • Author(s)
      Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品の連続生産を対象とするプロセスシステム工学研究2017

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] バイオプロセスイノベーションと情報統合2017

    • Author(s)
      杉山 弘和
    • Organizer
      INCHEM TOKYO 2017産学官マッチングフォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] プロセス選択肢としての連続生産2017

    • Author(s)
      杉山 弘和
    • Organizer
      ISPE日本本部 第16回冬季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品錠剤製造プロセスにおけるバッチ・連続技術の製品品質評価2017

    • Author(s)
      松並 研作, 長門 琢也, 長谷川 浩司, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Research needs and opportunities for process systems engineering in pharmaceutical manufacturing2017

    • Author(s)
      Hiorkazu Sugiyama
    • Organizer
      6th Conference on Emerging Energy & Process Technology 2017 (CONCEPT 2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 患者特性を考慮した残薬削減対策の選択支援手法2017

    • Author(s)
      原田 典和, 矢作 尚久, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品・再生医療製品の製造におけるモデルベースト設計2017

    • Author(s)
      杉山 弘和
    • Organizer
      第16回日本再生医療学会総会
    • Place of Presentation
      仙台国際センター, 宮城県仙台市
    • Year and Date
      2017-03-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Process systems engineering approaches for drug product manufacturing: from tablets to injectables2017

    • Author(s)
      Hirokazu Sugiyama, Kensaku Matsunami, Keisho Yabuta
    • Organizer
      The 27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Integrated process performance assessment considering uncertainty in biopharmaceutical manufacturing operations2017

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      The 27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品・再生医療製品の製造におけるモデルベースト設計2017

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品製造における過酸化水素を用いた除染プロセスの設計手法2017

    • Author(s)
      藪田 啓奨, 二村 はるか, 川崎 康司, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス, 東京都江東区
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] iPS細胞の産業化に向けた凍結・解凍プロセス設計2017

    • Author(s)
      林 勇佑, 紀ノ岡 正博, 堀口 一樹, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第83年会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Pharma PSE 研究最前線 ~除染・シングルユース・連続製造~2017

    • Author(s)
      杉山 弘和
    • Organizer
      第6回最新の医薬・医療に関するGMP・技術動向を考える会 パイロットセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Large-scale experimental comparison of batch and continuous technologies for pharmaceutical tablet manufacturing2017

    • Author(s)
      Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 医薬品製造における意思決定とスマート化 ~プロセス設計から継続的改善まで~2017

    • Author(s)
      杉山 弘和
    • Organizer
      バレオコンエグゼクティブセミナー2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Pharma PSE: Developing Novel Design Methodologies for Pharmaceutical Manufacturing Processes2017

    • Author(s)
      杉山 弘和
    • Organizer
      日本学術振興会プロセスシステム工学第143委員会 平成29年度第3回研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] 注射剤製造プロセスの多階層・多目的設計プラットフォーム2017

    • Author(s)
      白畑 春来, Shant Dakessian, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第49回秋季大会
    • Data Source
      KAKENHI-PROJECT-17H04964
  • [Presentation] Process model of sterile drug product manufacturing for yield enhancement2016

    • Author(s)
      Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Multiobjective retrofitting methodology for manufacturing processes of active pharmaceutical ingredients considering environmental, health and safety risks2016

    • Author(s)
      Hirokazu Sugiyama, Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao
    • Organizer
      26th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Bernardin Congress Centre, Portoroz, Slovenia
    • Year and Date
      2016-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Conducting process systems engineering research on pharmaceutical manufacturing2016

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品製造を対象とするプロセスシステム工学2016

    • Author(s)
      杉山 弘和
    • Organizer
      第22回流動化・粒子プロセッシングシンポジウム
    • Place of Presentation
      東京大学生産技術研究所, 東京都目黒区
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] バッチ・連続技術を考慮した医薬品錠剤製造のプロセスシステム工学的アプローチ2016

    • Author(s)
      松並 研作, 宮野 拓也, 荒井 宏明, 中川 弘司, 平尾 雅彦, 杉山 弘和
    • Organizer
      第22回流動化・粒子プロセッシングシンポジウム
    • Place of Presentation
      東京大学生産技術研究所, 東京都目黒区
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Product loss reduction in batch manufacturing of sterile drug products2016

    • Author(s)
      Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Product loss reduction in batch manufacturing of sterile drug products2016

    • Author(s)
      Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品連続製造を対象とするプロセスシステム工学研究2016

    • Author(s)
      杉山 弘和, 松並 研作
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学常三島キャンパス, 徳島県徳島市
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Process performance assessment based on stochastic simulation in sterile drug product manufacturing2016

    • Author(s)
      Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学常三島キャンパス, 徳島県徳島市
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品製造プロセスの設計問題2016

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会 第81年会
    • Place of Presentation
      北海道大学 札幌キャンパス, 北海道札幌市北区
    • Year and Date
      2016-03-13
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Design problem of pharmaceutical manufacturing processes2016

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2016
    • Place of Presentation
      Hilton San Francisco Union Square, San Francisco, U.S.A
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品原薬製造における溶媒回収プロセス設計2016

    • Author(s)
      徐 夢荷, 松浦 麻衣, 森川 裕介, 杉山 弘和
    • Organizer
      化学工学会 第81年会
    • Place of Presentation
      関西大学 千里山キャンパス, 大阪府吹田市
    • Year and Date
      2016-03-13
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] バイオプロセスイノベーションにおける統合化工学の役割2016

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学常三島キャンパス, 徳島県徳島市
    • Year and Date
      2016-09-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Pharma PSE研究の今後とCOPとしての展開2016

    • Author(s)
      杉山 弘和
    • Organizer
      2016年ISPE日本本部年次大会
    • Place of Presentation
      タワーホール船堀, 東京都江戸川区
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Process model of sterile drug product manufacturing for yield enhancement2016

    • Author(s)
      Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Design method for pharmaceutical tablet production considering batch & continuous technologies2016

    • Author(s)
      Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Conducting process systems engineering research on pharmaceutical Mmnufacturing2016

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Design method for pharmaceutical tablet production considering batch & continuous technologies2016

    • Author(s)
      Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 注射剤製造プロセス設計のためのリスク評価モデル2016

    • Author(s)
      白畑 春来, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学常三島キャンパス, 徳島県徳島市
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Hybrid approach for improving drug product manufacturing efficiency2016

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Biopharmaceutical process optimization: needs and benefits of numerical simulation approaches2016

    • Author(s)
      Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
    • Organizer
      第22回流動化・粒子プロセッシングシンポジウム
    • Place of Presentation
      東京大学生産技術研究所, 東京都目黒区
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Developing process models of hydrogen peroxide decontamination in pharmaceutical manufacturing2016

    • Author(s)
      Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2016
    • Place of Presentation
      Hilton San Francisco Union Square, San Francisco, U.S.A
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Mid-term scheduling model based on state-task-network considering plant specific constraints in pharmaceutical manufacturing2016

    • Author(s)
      Gioele Casola, Lukas Gallus Eberle, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      26th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Bernardin Congress Centre, Portoroz, Slovenia
    • Year and Date
      2016-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Hybrid approach for improving drug product manufacturing efficiency2016

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Monte carlo simulation-based method for process performance assessment in sterile manufacturing of biopharmaceuticals2016

    • Author(s)
      Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2016
    • Place of Presentation
      Hilton San Francisco Union Square, San Francisco, U.S.A
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
    • Place of Presentation
      Ito International Research Center, Bunkyo-ku, Tokyo, Japan
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Selection support methodology between batch and continuous technologies for pharmaceutical tablet manufacturing processes2016

    • Author(s)
      Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2016
    • Place of Presentation
      Hilton San Francisco Union Square, San Francisco, U.S.A
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] バッチ・連続技術の選択を考慮した医薬品錠剤製造プロセスの設計手法2016

    • Author(s)
      松並 研作, 宮野 拓也, 新井 宏明, 中川 弘司, 平尾 雅彦, 杉山 弘和
    • Organizer
      化学工学会 第81年会
    • Place of Presentation
      関西大学 千里山キャンパス, 大阪府吹田市
    • Year and Date
      2016-03-13
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Systematic retrofitting methodology for pharmaceutical drug purification processes2015

    • Author(s)
      Gioele Casola, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2015
    • Place of Presentation
      Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Systematic retrofitting methodology for recrystallization of thermally unstable active pharmaceutical ingredients2015

    • Author(s)
      Gioele Casola, Hirokazu Sugiyama, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao
    • Organizer
      12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Bella Center, Copenhagen, Denmark
    • Year and Date
      2015-05-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Improving yield of drug product manufacturing with hybrid approach2015

    • Author(s)
      Lukas Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Organizer
      AIChE annual meeting 2015
    • Place of Presentation
      Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 無菌製剤製造における収率改善のためのプロセスモデル構築2015

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会 第47年回秋季大会
    • Place of Presentation
      北海道大学 札幌キャンパス, 北海道札幌市北区
    • Year and Date
      2015-09-09
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Optimal scheduling of liquid drug product manufacturing2015

    • Author(s)
      Lukas Gallus Eberle, Elisabet Capón-Garcia, Martin Senninger, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Organizer
      12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Bella Center, Copenhagen, Denmark
    • Year and Date
      2015-05-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Systems engineering approaches for designing pharmaceutical manufacturing processes2015

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      Pharma Process Forum
    • Place of Presentation
      Palau de Congressos, Barcelona, Spain
    • Year and Date
      2015-10-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] The role of modeling, simulation and optimization approaches in the design of pharmaceutical production processes2015

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2015
    • Place of Presentation
      Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Systems engineering approaches for designing pharmaceutical manufacturing processes2015

    • Author(s)
      Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
    • Organizer
      AIChE annual meeting 2015
    • Place of Presentation
      Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Process-based method for reducing product losses in pharmaceutical manufacturing2015

    • Author(s)
      Hirokazu Sugiyama, Masahiko Hirao
    • Organizer
      12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Bella Center, Copenhagen, Denmark
    • Year and Date
      2015-05-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Improving pharmaceutical batch production processes with data-based tiered approach2015

    • Author(s)
      Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Organizer
      12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Bella Center, Copenhagen, Denmark
    • Year and Date
      2015-05-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes2014

    • Author(s)
      Lukas Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
    • Organizer
      24th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Budapest, Hungary
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] Applying Process Systems Engineering in Pharmaceutical Industry: A New Paradigm2014

    • Author(s)
      Sugiyama Hirokazu
    • Organizer
      化学工学会 第79年会
    • Place of Presentation
      岐阜大学柳戸キャンパス
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] Integration Framework for Improving Quality and Cost-Effectiveness in Pharmaceutical Production Processes2014

    • Author(s)
      Hirokazu Sugiyama, Masahiko Hirao
    • Organizer
      24th European Symposium on Computer Aided Process Engineering
    • Place of Presentation
      Budapest, Hungary
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 医薬品製造プロセスの継続的改善を支援する統合化アプローチ2014

    • Author(s)
      杉山 弘和
    • Organizer
      インターフェックスジャパン 専門技術セミナー
    • Place of Presentation
      東京ビッグサイト
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 医薬品製造を対象とするプロセス改善支援手法2014

    • Author(s)
      伊藤 正晃、杉山 弘和、平尾 雅彦
    • Organizer
      化学工学会 第79年会
    • Place of Presentation
      岐阜大学柳戸キャンパス
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 医薬品製造の品質・生産性向上にむけたプロセスベースト・アプローチ2014

    • Author(s)
      杉山 弘和、伊藤 正晃、平尾 雅彦
    • Organizer
      化学工学会 第79年会
    • Place of Presentation
      岐阜大学柳戸キャンパス
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 医薬品製造プロセスの品質・生産性向上に向けた統合化工学2013

    • Author(s)
      杉山 弘和
    • Organizer
      INCHEM TOKYO 2013
    • Place of Presentation
      東京ビッグサイト
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 石油精製への影響を考慮したバイオマス利活用システム設計2013

    • Author(s)
      Maghfuri Baharuddin, 杉山弘和, 菊池康紀, 平尾雅彦
    • Organizer
      化学工学会第45回秋季大会
    • Place of Presentation
      岡山大学(岡山)
    • Year and Date
      2013-09-16
    • Data Source
      KAKENHI-PROJECT-23360404
  • [Presentation] 医薬品製造プロセスの品質・生産性向上に向けた統合化工学2013

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会 第45回秋季大会
    • Place of Presentation
      岡山大学津島(東)キャンパス
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 石油精製への影響を考慮したバイオマス利活用システム設計2013

    • Author(s)
      Maghfuri Baharuddin, 杉山 弘和, 菊池 康紀, 平尾 雅彦
    • Organizer
      化学工学会第45回秋季大会
    • Place of Presentation
      岡山大学(岡山)
    • Data Source
      KAKENHI-PROJECT-23360404
  • [Presentation] 医薬品原薬精製を対象とするシミュレーション技術を用いたプロセス改善手法

    • Author(s)
      Casola Gioele, 杉山 弘和, 吉川 覚, 中西 勇夫, 平尾 雅彦
    • Organizer
      化学工学会 第80年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス(東京都江東区)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品製造バッチプロセスを対象とする数理モデル構築

    • Author(s)
      藪田 啓奨, 杉山 弘和, 平尾 雅彦
    • Organizer
      化学工学会 第80年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス(東京都江東区)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品製造を対象とするモデル化・シミュレーション・最適化研究

    • Author(s)
      杉山 弘和
    • Organizer
      化学工学会 第80年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス(東京都江東区)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品原薬製造における多目的評価に基づく環境・健康・安全リスク低減手法

    • Author(s)
      瀬川 晶子, 杉山 弘和, 吉川 覚, 遠山 貴之, 中西 勇夫, 平尾 雅彦
    • Organizer
      化学工学会 第80年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス(東京都江東区)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 医薬品産業における品質・生産性向上に向けた新たな挑戦

    • Author(s)
      杉山 弘和
    • Organizer
      2013年度ISPE日本本部冬季大会
    • Place of Presentation
      メルパルク大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] 医薬品製造におけるプロセスシステム工学の新展開

    • Author(s)
      杉山 弘和
    • Organizer
      日本学術振興会プロセスシステム工学第143委員会H25年度第5回研究会
    • Place of Presentation
      キャンパスイノベーションセンター(CIC)東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • [Presentation] モンテカルロ法を用いた医薬品製造プロセスのリードタイム改善

    • Author(s)
      杉山 弘和, Eberle Lukas, Schmidt Rainer
    • Organizer
      化学工学会 第46回秋季大会
    • Place of Presentation
      九州大学伊都キャンパス(福岡県福岡市)
    • Year and Date
      2014-09-17 – 2014-09-19
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 注射剤製造におけるシングルユース・マルチユース技術の選択支援手法

    • Author(s)
      白畑 春来, 杉山 弘和, 平尾 雅彦
    • Organizer
      化学工学会 第80年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス(東京都江東区)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] 品質・経済性を考慮した医薬品原料使用プロセスの多目的設計手法

    • Author(s)
      飯田 剛之, 太田 耕右, 哘崎 智仁, 杉山 弘和
    • Organizer
      化学工学会 第80年会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス(東京都江東区)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26820343
  • [Presentation] Integration approach for realizing superior production processes in the pharmaceutical industry

    • Author(s)
      Hirokazu Sugiyama
    • Organizer
      Sicherheit und Umweltschutz in der Chemie, Seminarreihe Fruehjahrssemester 2014
    • Place of Presentation
      ETH Zurich, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-25889016
  • 1.  HIRAO Masahiko (80282573)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  UEHARA Emi (10648132)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  NAKATANI Jun (40436522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KIKUCHI Yasunori (70545649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  AMASAWA ERI (80804989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  Kano Manabu (30263114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  紀ノ岡 正博 (40234314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 8.  金 尚弘 (60735504)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  矢作 尚久 (30365431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  太田 誠一 (40723284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  西川 昌輝 (40843149)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Hungerbuehler Konrad
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi