Sugiyama Hirokazu 杉山弘和

… Alternative Names

Researcher Number	70701340
Other IDs
Affiliation (Current)	2022: 東京大学, 大学院工学系研究科(工学部), 教授
Affiliation (based on the past Project Information) *help	2021: 東京大学, 大学院工学系研究科(工学部), 教授 2016 – 2020: 東京大学, 大学院工学系研究科(工学部), 准教授 2017: 東京大学, 大学院工学系研究科, 准教授 2013 – 2015: 東京大学, 工学(系)研究科(研究院), 准教授 2013: 東京大学, 大学院・工学系研究科, 准教授
Review Section/Research Field	Principal Investigator Reaction engineering/Process system / Basic Section 27020:Chemical reaction and process system engineering-related / Medium-sized Section 27:Chemical engineering and related fields Except Principal Investigator Recycling engineering / Social systems engineering/Safety system / Basic Section 27020:Chemical reaction and process system engineering-related
Keywords	Principal Investigator プロセス設計 / 医薬品製造 / シミュレーション / プロセスシステム工学 / 注射剤 / 多目的意思決定 / 意思決定 / iPS細胞 / モデル化 / 最適化 … More Except Principal Investigator リサイクル / マテリアルフロー / LCA / 物質循環 / シナリオ分析 / プラスチック / 容器包装 / 素材間連関 / 消費者行動 / ＬＣＡ / 環境政策 / 国際情報交換(台湾) / 紙 / システム安全 / 製品安全設計 / リチウムイオン電池 / ライフサイクル / フォルトツリー解析 / 安全設計 / リユース / 環境負荷 / フォールトの木解析 / 難燃性電解液 / 事故事例分析 / 内部短絡 / シミュレーションモデル / 連続生産 / 医薬品 / デインスペース / 機械学習 Less

Development of rapid manufacturing support system for anti-pandemic drugsPrincipal Investigator
- Principal Investigator
  
  杉山弘和
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27020:Chemical reaction and process system engineering-related
- Research Institution
  The University of Tokyo
Development of innovative management strategy for pharmaceutical continuous manufacturing processes
- Principal Investigator
  
  加納学
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27020:Chemical reaction and process system engineering-related
- Research Institution
  Kyoto University
Multiscale design platform for innovating freezing processes of iPS cellsPrincipal Investigator
- Principal Investigator
  
  杉山弘和
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  The University of Tokyo
Development of innovative process design methodology for pharmaceutical manufacturing and tool implementationPrincipal Investigator
- Principal Investigator
  
  Sugiyama Hirokazu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Reaction engineering/Process system
- Research Institution
  The University of Tokyo
Safety design method of Lithium ion battery using systems approach
- Principal Investigator
  
  Hirao Masahiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Social systems engineering/Safety system
- Research Institution
  The University of Tokyo
Development of multiobjective process design method for quality and productivity improvement in pharmaceutical manufacturingPrincipal Investigator
- Principal Investigator
  
  Sugiyama Hirokazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Reaction engineering/Process system
- Research Institution
  The University of Tokyo
製薬プロセスの品質・生産性向上にむけた意思決定支援手法の開発Principal Investigator
- Principal Investigator
  
  杉山弘和
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Reaction engineering/Process system
- Research Institution
  The University of Tokyo
Material flow model for the evaluation of recycling considering relations between different materials
- Principal Investigator
  
  HIRAO Masahiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Recycling engineering
- Research Institution
  The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent

[Book] 固形剤の連続製造プロセス設計と経済性評価2020
- Author(s)
  松並研作, 杉山弘和
- Total Pages
  9
- Publisher
  技術情報協会
- ISBN
  9784861048203
- Data Source
  KAKENHI-PROJECT-17H04964
[Book] "連続生産を対象とするプロセスシステム工学研究" 固形製剤とバイオ原薬の連続生産2019
- Author(s)
  杉山弘和, 松並研作
- Total Pages
  10
- Publisher
  シーエムシー出版
- ISBN
  9784781314259
- Data Source
  KAKENHI-PROJECT-17H04964
[Book] 注射剤製造における無菌性保証・バリデーションと異物低減ノウハウ・検査事例2016
- Author(s)
  杉山弘和
- Total Pages
  23
- Publisher
  サイエンスアンドテクノロジー
- Data Source
  KAKENHI-PROJECT-26820343
[Book] 抗体医薬における細胞構築・培養・ダウンストリームのすべて第8編第1章医薬品生産における統合化工学とは2015
- Author(s)
  杉山弘和（分担著者）大政健史（監修）
- Total Pages
  7
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-26820343
[Book] “医薬品生産における統合化工学とは” 抗体医薬品における細胞構築・培養・ダウンストリームのすべて, 大政健史（編）2015
- Author(s)
  杉山弘和
- Total Pages
  9
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells2021
- Author(s)
  Hayashi Yusuke, Horiguchi Ikki, Kino-oka Masahiro, Sugiyama Hirokazu
- Journal Title
  
  Computers & Chemical Engineering
  
  Volume: 144 Pages: 107150-107150
- DOI
  10.1002/term.3127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Computational screening of cryoprotective agents for regenerative medical products using quantum chemistry and molecular dynamics simulations2021
- Author(s)
  Hayashi Yusuke, Nakajima Yuka, Sugiyama Hirokazu
- Journal Title
  
  Cryobiology
  
  Volume: in press
- DOI
  10.1016/j.cryobiol.2021.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21102, KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第13回：ヒトiPS細胞の緩慢凍結プロセスにおける冷却温度プロファイルのモデルベースト評価2021
- Author(s)
  林勇佑, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 37 Pages: 255-259
- Data Source
  KAKENHI-PROJECT-20K21102
[Journal Article] 固形剤製造プロセスの経済性評価シミュレーションとツール実装2021
- Author(s)
  杉山弘和, 松並研作
- Journal Title
  
  化学装置
  
  Volume: 1 Pages: 57-62
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Data-driven anomaly detection and diagnostics for changeover processes in biopharmaceutical drug product manufacturing2021
- Author(s)
  Hayashi Yusuke, Horiguchi Ikki, Kino-oka Masahiro, Sugiyama Hirokazu
- Journal Title
  
  Chemical Engineering Research and Design
  
  Volume: 144 Pages: 107150-107150
- DOI
  10.1016/j.compchemeng.2020.107150
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21102, KAKENHI-PROJECT-17H04964
[Journal Article] Determining key parameters of continuous wet granulation for tablet quality and productivity: A case in ethenzamide2020
- Author(s)
  Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Hirokazu Sugiyama
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 579 Pages: 119160-119160
- DOI
  10.1016/j.ijpharm.2020.119160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
[Journal Article] Pharma PSE Spotlight 第12回：無菌製剤製造における除染プロセスとスケジューリングの統合設計2020
- Author(s)
  藪田啓奨, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 36 Pages: 2421-2426
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Impact of H2O2 Sorption by Polymers on the Duration of Aeration in Pharmaceutical Decontamination2020
- Author(s)
  Sugiyama Hirokazu, Shiokaramatsu Masaki, Kagihiro Masashi, Fukumori Kazuhiro, Horiguchi Ikki, Kino‐oka Masahiro
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 14 Pages: 1641-1651
- DOI
  10.1016/j.xphs.2020.05.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] 固形製剤の製法設計のためのシミュレーションツール2020
- Author(s)
  松並研作, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 36 Pages: 1257-1262
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing2020
- Author(s)
  Kensaku Matsunami, Fabian Sternal, Keita Yaginuma, Shuichi Tanabe, Hiroshi Nakagawa, Hirokazu Sugiyama
- Journal Title
  
  BMC Chemical Engineering
  
  Volume: 2 Pages: 6-6
- DOI
  10.1186/s42480-020-0028-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
[Journal Article] Multi-stage and multi-objective decision-support tool for biopharmaceutical drug product manufacturing: Equipment technology evaluation2020
- Author(s)
  Z?rcher Philipp, Shirahata Haruku, Badr Sara, Sugiyama Hirokazu
- Journal Title
  
  Chemical Engineering Research and Design
  
  Volume: 161 Pages: 240-252
- DOI
  10.1016/j.cherd.2020.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第13回：ヒトiPS細胞の緩慢凍結プロセスにおける冷却温度プロファイルのモデルベースト評価2020
- Author(s)
  林勇佑, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 37 Pages: 255-259
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Integrated design of H2O2 decontamination processes and scheduling in sterile drug product manufacturing2020
- Author(s)
  Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Hirokazu Sugiyama
- Journal Title
  
  Journal of Pharmaceutical Innovation
  
  Volume: accepted
- DOI
  10.1007/s12247-019-09410-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Multiobjective Dynamic Optimization of Slow Freezing Processes for Human Induced Pluripotent Stem Cells by Modeling Intracontainer Condition2020
- Author(s)
  Hayashi Yusuke, Horiguchi Ikki, Kino-oka Masahiro, Sugiyama Hirokazu
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 48 Pages: 265-270
- DOI
  10.1016/b978-0-12-823377-1.50045-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21102
[Journal Article] Online Decision-Support Tool “TECHoice” for the Equipment Technology Choice in Sterile Filling Processes of Biopharmaceuticals2019
- Author(s)
  Haruku Shirahata, Sara Badr, Yuki Shinno, Shuta Hagimori, Hirokazu Sugiyama
- Journal Title
  
  Processes
  
  Volume: 7 Pages: 448-448
- DOI
  10.3390/pr7070448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
[Journal Article] Pharma PSE Research at The University of Tokyo2019
- Author(s)
  Hirokazu Sugiyama
- Journal Title
  
  PD2M Newsletter
  
  Volume: 2 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Relevance of regulatory constraints in designing pharmaceutical manufacturing processes: A case study on waste solvent recovery2019
- Author(s)
  Sugiyama Hirokazu、Morikawa Yusuke、Matsuura Mai、Xu Menghe
- Journal Title
  
  Sustainable Production and Consumption
  
  Volume: 17 Pages: 136-147
- DOI
  10.1016/j.spc.2018.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第9回：バイオ医薬品無菌充填工程を対象とするオンライン技術選択支援ツール"TECHoice"2019
- Author(s)
  白畑春来, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 35 Pages: 2605-2610
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Data mining algorithm for pre-processing biopharmaceutical drug product manufacturing records2019
- Author(s)
  Casola Gioele、Siegmund Christian、Mattern Markus、Sugiyama Hirokazu
- Journal Title
  
  Computers & Chemical Engineering
  
  Volume: 124 Pages: 253-269
- DOI
  10.1016/j.compchemeng.2018.12.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Integrated white-box models for designing freezing processes of human induced pluripotent stem cells considering diversity within a container2019
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 46 Pages: 877-882
- DOI
  10.1016/b978-0-12-818634-3.50147-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation2019
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
- Journal Title
  
  Computers and Chemical Engineering
  
  Volume: 132 Pages: 106597-106597
- DOI
  10.1016/j.compchemeng.2019.106597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] A distribution-based approach for determining lot sizes in the filling of human-induced pluripotent stem cells2019
- Author(s)
  Hirokazu Sugiyama, Masaki Shiokaramatsu, Masahiro Kino-oka
- Journal Title
  
  Regenerative Therapy
  
  Volume: 12 Pages: 94-101
- DOI
  10.1016/j.reth.2019.04.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Dynamic Modelling and Simulation of Chinese Hamster Ovary (CHO) Cell Fermentation for Advanced Biopharmaceutical Manufacturing2019
- Author(s)
  Haruku Shirahata, Samir Diab, Hirokazu Sugiyama, Dimitrios I. Gerogiorgi
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 46 Pages: 673-678
- DOI
  10.1016/b978-0-12-818634-3.50113-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
[Journal Article] Pharma PSE Spotlight 第7回：バイオ医薬品無菌充填におけるシングルユース・マルチユース技術の多目的選択支援ツール2019
- Author(s)
  白畑春来, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 35 Pages: 377-383
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第10回：容器内ばらつきのモデル化によるヒトiPS細胞の緩慢凍結プロセス設計2019
- Author(s)
  林勇佑, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 35 Pages: 2965-2968
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Alternative generation and multiobjective evaluation using a design framework: Case study on sterile filling processes of biopharmaceuticals2019
- Author(s)
  Shirahata Haruku、Badr Sara、Dakessian Shant、Sugiyama Hirokazu
- Journal Title
  
  Computers & Chemical Engineering
  
  Volume: 123 Pages: 286-299
- DOI
  10.1016/j.compchemeng.2018.12.019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
[Journal Article] Multiobjective decision-support tools for the choice between single-use and multi-use technologies in sterile filling of biopharmaceuticals2019
- Author(s)
  Shirahata Haruku、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  Computers & Chemical Engineering
  
  Volume: 122 Pages: 114-128
- DOI
  10.1016/j.compchemeng.2018.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
[Journal Article] Dynamic modelling, simulation and economic evaluation of two CHO cell-based production modes towards developing biopharmaceutical manufacturing processes2019
- Author(s)
  Haruku Shirahata, Samir Diab, Hirokazu Sugiyama, Dimitrios I. Gerogiorgis
- Journal Title
  
  Chemical Engineering Research and Design
  
  Volume: 150 Pages: 218-233
- DOI
  10.1016/j.cherd.2019.07.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
[Journal Article] A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide2019
- Author(s)
  Matsunami Kensaku、Nagato Takuya、Hasegawa Koji、Sugiyama Hirokazu
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 559 Pages: 210-219
- DOI
  10.1016/j.ijpharm.2019.01.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
[Journal Article] Pharma PSE Spotlight 第11回：経済性評価に基づく注射剤製造プロセスのロットサイズ決定2019
- Author(s)
  山田真弘, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 36 Pages: 871-875
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第8回：エテンザミドを用いた医薬品錠剤製造におけるバッチ・連続技術の大スケール実験的検討2019
- Author(s)
  松並研作, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 35 Pages: 1533-1537
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Approach for Multicriteria Equipment Redesign in Sterile Manufacturing of Biopharmaceuticals2018
- Author(s)
  Zeberli Anicia、Casola Gioele、Badr Sara、Siegmund Christian、Mattern Markus、Sugiyama Hirokazu
- Journal Title
  
  Journal of Pharmaceutical Innovation
  
  Volume: in press
- DOI
  10.1007/s12247-018-9355-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Decision Support Method for the Choice between Batch and Continuous Technologies in Solid Drug Product Manufacturing2018
- Author(s)
  Matsunami Kensaku、Miyano Takuya、Arai Hiroaki、Nakagawa Hiroshi、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  Industrial & Engineering Chemistry Research
  
  Volume: 57 Pages: 9798-9809
- DOI
  10.1021/acs.iecr.7b05230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
[Journal Article] Models for Designing Hydrogen Peroxide Decontamination Processes in Sterile Drug Product Manufacturing2018
- Author(s)
  Yabuta Keisho、Futamura Haruka、Kawasaki Koji、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  Computer Aided Process Engineering
  
  Volume: 43 Pages: 1613-1618
- DOI
  10.1016/b978-0-444-64235-6.50281-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第5回：無菌製剤製造における収率向上のためのプロセスモデル2018
- Author(s)
  藪田啓奨, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 34 Pages: 1329-1334
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Design-oriented regression models for H 2 O 2 decontamination processes in sterile drug product manufacturing considering rapidity and sterility2018
- Author(s)
  Yabuta Keisho、Futamura Haruka、Kawasaki Koji、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 548 Pages: 466-473
- DOI
  10.1016/j.ijpharm.2018.06.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Quantitative Analysis on the Relevance of Regulatory Constraints in Designing Pharmaceutical Manufacturing Processes2018
- Author(s)
  Sugiyama Hirokazu、Morikawa Yusuke、Matsuura Mai、Xu Menghe
- Journal Title
  
  Computer Aided Process Engineering
  
  Volume: 44 Pages: 2119-2124
- DOI
  10.1016/b978-0-444-64241-7.50348-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第4回：注射剤製造における賦形剤使用プロセスの多目的設計手法2018
- Author(s)
  杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 34 Pages: 300-304
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Industrial Scale Experiments towards the Development of Process Evaluation Models for Continuous Pharmaceutical Tablet Manufacturing2018
- Author(s)
  Matsunami Kensaku、Nagato Takuya、Hasegawa Koji、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 43 Pages: 1655-1660
- DOI
  10.1016/b978-0-444-64235-6.50288-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
[Journal Article] Data mining-based algorithm for pre-processing biopharmaceutical manufacturing records2018
- Author(s)
  Casola Gioele、Siegmund Christian、Mattern Markus、Sugiyama Hirokazu
- Journal Title
  
  Computer Aided Process Engineering
  
  Volume: 44 Pages: 2263-2268
- DOI
  10.1016/b978-0-444-64241-7.50372-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Multilayer and Multiobjective Design Platform for Drug Product Manufacturing Processes of Biopharmaceuticals2018
- Author(s)
  Shirahata Haruku、Dakessian Shant、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 44 Pages: 301-306
- DOI
  10.1016/b978-0-444-64241-7.50045-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J13892
[Journal Article] 製剤と粒子設計：意思決定の切り口からみた製剤の連続生産2018
- Author(s)
  杉山弘和, 松並研作
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 34 Pages: 2261-2265
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第6回：過酸化水素除染プロセスの多目的設計に向けた統計モデル2018
- Author(s)
  藪田啓奨, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 34 Pages: 2941-2946
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Economic Evaluation of Batch and Continuous Manufacturing Technologies for Solid Drug Products during Clinical Development2018
- Author(s)
  Matsunami Kensaku、Tanabe Shuichi、Nakagawa Hiroshi、Hirao Masahiko、Sugiyama Hirokazu
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 44 Pages: 2131-2136
- DOI
  10.1016/b978-0-444-64241-7.50350-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964, KAKENHI-PROJECT-18J22793
[Journal Article] Uncertainty-conscious Methodology for Process Performance Assessment in Biopharmaceutical Drug Product Manufacturing2017
- Author(s)
  Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Journal Title
  
  AIChE Journal
  
  Volume: 64 Pages: 1272-1284
- DOI
  10.1002/aic.16020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第3回： ISPE日本本部 Pharma PSE COPの紹介2017
- Author(s)
  杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 33 Pages: 2911-2916
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Pharma PSE Spotlight 第１回：無菌製剤製造における製品ロス低減のための計画手法2017
- Author(s)
  杉山弘和, 伊藤正晃
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 33 Pages: 975-979
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Innovative approach for identifying root causes of glass defects in sterile drug product manufacturing2017
- Author(s)
  Lukas Eberle, Alexander Svensson, Andreas Graser, Joerg Luemkemann, Hirokazu Sugiyama, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  European Journal of Pharmaceutical Sciences
  
  Volume: 104 Pages: 162-170
- DOI
  10.1016/j.ejps.2017.03.015
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Pharma PSE Spotlight 第2回：注射剤製造におけるシングルユース・マルチユース技術の選択支援手法2017
- Author(s)
  白畑春来, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 33 Pages: 1529-1535
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Integrated Process Performance Assessment Considering Uncertainty in Biopharmaceutical Manufacturing Operations2017
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 40 Pages: 2227-2232
- DOI
  10.1016/b978-0-444-63965-3.50373-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Decision-support method for the choice between single-use and multi-use technologies in sterile drug product manufacturing2017
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Journal of Pharmaceutical Innovation
  
  Volume: 12 Pages: 1-13
- DOI
  10.1007/s12247-016-9264-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] 連続生産を対象とするプロセスシステム工学研究2017
- Author(s)
  松並研作, 杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 33 Pages: 2619-2625
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Process Systems Engineering Approaches for Drug Product Manufacturing: from Tablets to Injectables2017
- Author(s)
  Hirokazu Sugiyama, Kensaku Matsunami, Keisho Yabuta
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 40 Pages: 2785-2790
- DOI
  10.1016/b978-0-444-63965-3.50466-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Process model for enhancing yield in sterile drug product manufacturing2017
- Author(s)
  Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Journal of Pharmaceutical Innovation
  
  Volume: accepted for publication
- DOI
  10.1007/s12247-017-9278-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Risk Evaluation Models for the Design of Parenterals Manufacturing Processes2017
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 40 Pages: 2791-2796
- DOI
  10.1016/b978-0-444-63965-3.50467-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04964
[Journal Article] Product loss reduction in batch manufacturing of sterile drug products2016
- Author(s)
  Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Design method for pharmaceutical tablet production considering batch & continuous technologies2016
- Author(s)
  Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] 製薬プロセスシステム工学Pharma PSEの開拓2016
- Author(s)
  杉山弘和
- Journal Title
  
  Pharm Tech Japan
  
  Volume: 32 Pages: 2421-2426
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Multiobjective retrofitting methodology for manufacturing processes of active pharmaceutical ingredients considering environmental, health and safety risks2016
- Author(s)
  Hirokazu Sugiyama, Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao
- Journal Title
  
  Computer Aided Chemical Engineering (Proceedings of 26th European Symposium on Computer Aided Process Engineering)
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Rigorous approach to scheduling of sterile drug product manufacturing2016
- Author(s)
  Lukas Gallus Eberle, Elisabet Capon Carcia, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  Computers and Chemical Engineering
  
  Volume: 87 Pages: 82-89
- DOI
  10.1016/j.compchemeng.2016.07.028
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Design method for pharmaceutical tablet production considering batch & continuous technologies2016
- Author(s)
  Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] 医薬品製造を対象とするプロセスシステム工学の最新動向2016
- Author(s)
  杉山弘和
- Journal Title
  
  化学工学
  
  Volume: 80 Pages: 450-450
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Data-driven tiered procedure for enhancing yield in drug product manufacturing2016
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  Computers and Chemical Engineering
  
  Volume: 87 Pages: 82-89
- DOI
  10.1016/j.compchemeng.2015.12.012
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Hybrid approach for improving drug product manufacturing efficiency2016
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Product loss reduction in batch manufacturing of sterile drug products2016
- Author(s)
  Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Mid-term scheduling model based on state-task-network considering plant specific constraints in pharmaceutical manufacturing2016
- Author(s)
  Gioele Casola, Lukas Gallus Eberle, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Journal Title
  
  Computer Aided Chemical Engineering (Proceedings of 26th European Symposium on Computer Aided Process Engineering)
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] 医薬品製造を対象とするモデル化・シミュレーション・最適化研究2016
- Author(s)
  杉山弘和
- Journal Title
  
  クリーンテクノロジー
  
  Volume: 26 Pages: 65-68
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Process model of sterile drug product manufacturing for yield enhancement2016
- Author(s)
  Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Conducting process systems engineering research on pharmaceutical Mmnufacturing2016
- Author(s)
  Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Multiobjective retrofitting methodology for manufacturing processes of active pharmaceutical ingredients considering environmental, health and safety risks2016
- Author(s)
  Hirokazu Sugiyama, Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 38 Pages: 79-84
- DOI
  10.1016/b978-0-444-63428-3.50018-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Method for reducing environmental, health, and safety risks in active pharmaceutical ingredient manufacturing based on multiobjective evaluation2016
- Author(s)
  Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Process Safety and Environmental Protection
  
  Volume: 104 Pages: 304-313
- DOI
  10.1016/j.psep.2016.09.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Mid-term scheduling model based on state-task-network considering plant specific constraints in pharmaceutical manufacturing2016
- Author(s)
  Gioele Casola, Lukas Gallus Eberle, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 38 Pages: 1141-1146
- DOI
  10.1016/b978-0-444-63428-3.50195-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Conducting process systems engineering research on pharmaceutical manufacturing2016
- Author(s)
  Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Process model of sterile drug product manufacturing for yield enhancement2016
- Author(s)
  Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Hybrid approach for improving drug product manufacturing efficiency2016
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  Proceedings of the 7th International Symposium on Design, Operation and Control of Chemical Processes
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Optimal scheduling of liquid drug product manufacturing2015
- Author(s)
  Lukas Gallus Eberle, Elisabet Capón-Garcia, Martin Senninger, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  Computer Aided Chemical Engineering
  
  Volume: 36 Pages: 2033-2038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Planning Method for Reducing Product Losses in Manufacturing Sterile Drug Products2015
- Author(s)
  Hirokazu Sugiyama, Masaaki Ito, Masahiko Hirao
- Journal Title
  
  Journal of Chemical Engineering of Japan
  
  Volume: ?
- NAID
  130005104386
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Systematic retrofitting methodology for recrystallization of thermally unstable active pharmaceutical ingredients2015
- Author(s)
  Gioele Casola, Hirokazu Sugiyama, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao
- Journal Title
  
  Computer Aided Chemical Engineering (Proceedings of 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering)
  
  Volume: 36 Pages: 2171-2176
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Process-based method for reducing product losses in pharmaceutical manufacturing2015
- Author(s)
  Hirokazu Sugiyama, Masaaki Ito, Masahiko Hirao
- Journal Title
  
  Computer Aided Chemical Engineering (Proceedings of 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering)
  
  Volume: 36 Pages: 2189-2194
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] 医薬品製造プロセスの多目的設計2015
- Author(s)
  杉山弘和
- Journal Title
  
  化学工業
  
  Volume: 66 Pages: 952-958
- NAID
  40020659171
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Improving pharmaceutical batch production processes with data-based tiered approach2015
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  Computer Aided Chemical Engineering (Proceedings of 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering)
  
  Volume: 36 Pages: 1967-1972
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] 医薬品製造を対象とする新しいプロセスシステム工学「Pharma PSE」2015
- Author(s)
  杉山弘和
- Journal Title
  
  化学工学会バイオ部会ニュースレター
  
  Volume: 40 Pages: 3-6
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Systematic retrofitting methodology for pharmaceutical drug purification processes2015
- Author(s)
  Gioele Casola, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
- Journal Title
  
  Computers and Chemical Engineering
  
  Volume: 88 Pages: 177-188
- DOI
  10.1016/j.compchemeng.2015.05.024
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Multiobjective Design Method for the Use Processes of Pharmaceutical Excipients Considering Quality and Cost-Effectiveness2015
- Author(s)
  Takayuki Iida, Kosuke Ota, Tomohito Sasozaki, Hirokazu Sugiyama
- Journal Title
  
  Journal of Pharmaceutical Innovation
  
  Volume: 10 Pages: 313-323
- DOI
  10.1007/s12247-015-9228-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26820343, KAKENHI-PROJECT-15J07161
[Journal Article] Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes2014
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Journal Title
  
  24th European Symposium on Computer Aided Process Engineering
  
  Volume: A Pages: 463-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Reducing Energy Consumption in Pharmaceutical Production Processes: Framework and Case Study2014
- Author(s)
  Georg Mueller, Hirokazu Sugiyama, Simon Stocker, Rainer Schmidt
- Journal Title
  
  Journal of Pharmaceutical Innovation
  
  Volume: 9 Pages: 212-216
- DOI
  10.1007/s12247-014-9188-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Integration Framework for Improving Quality and Cost-Effectiveness in Pharmaceutical Production Processes2014
- Author(s)
  Sugiyama, H., Hirao, M.
- Journal Title
  
  24th European Symposium on Computer Aided Process Engineering
  
  Volume: in print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25889016
[Journal Article] Design of recycling system for poly(methyl methacrylate) (PMMA). Part 2: process hazards and material flow analysis2014
- Author(s)
  Y. Kikuchi, M. Hirao, H. Sugiyama, S. Papadokonstantakis, K.Hungerbuehler, T. Ookubo, A. Sasaki
- Journal Title
  
  International Journal of Life Cycle Assessment
  
  Volume: 19 Pages: 307-319
- DOI
  10.1007/s11367-013-0625-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23360404, KAKENHI-PROJECT-24246150
[Journal Article] Business Process Model of Continuous Improvement in Pharmaceutical Manufacturing2014
- Author(s)
  杉山弘和、シュミットライナー
- Journal Title
  
  KAGAKU KOGAKU RONBUNSHU
  
  Volume: 5 Issue: 3 Pages: 201-210
- DOI
  10.1252/kakoronbunshu.40.201
- NAID
  130004855782
- ISSN
  0386-216X, 1349-9203
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25889016
[Journal Article] Integration Framework for Improving Quality and Cost-Effectiveness in Pharmaceutical Production Processes2014
- Author(s)
  Hirokazu Sugiyama, Masahiko Hirao
- Journal Title
  
  24th European Symposium on Computer Aided Process Engineering
  
  Volume: A Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Improving Lead Time of Pharmaceutical Production Processes Using Monte Carlo Simulation2014
- Author(s)
  Eberle, L., Sugiyama, H., Schmidt, R.
- Journal Title
  
  Computers & Chemical Engineering
  
  Volume: accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25889016
[Journal Article] Improving Lead Time of Pharmaceutical Production Processes Using Monte Carlo Simulation2014
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Rainer Schmidt
- Journal Title
  
  Computers and Chemical Engineering
  
  Volume: 68 Pages: 255-263
- DOI
  10.1016/j.compchemeng.2014.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26820343
[Journal Article] Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes2014
- Author(s)
  Eberle, L., Sugiyama, H., Papadokonstantakis, S., Graser, A., Schmidt, R., Hungerbuehler, K.
- Journal Title
  
  Proceedings of 24th European Symposium on Computer Aided Process Engineering
  
  Volume: in print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25889016
[Patent] 情報提供装置及びプログラム2018
- Inventor(s)
  杉山弘和, 白畑春来, ツルヒャー　フィリップ　サミュエル
- Industrial Property Rights Holder
  杉山弘和, 白畑春来, ツルヒャー　フィリップ　サミュエル
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-163033
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] エージェントベーストモデルを用いた他家iPS細胞治療の費用対効果分析2021
- Author(s)
  林勇佑, 大石宏太, 杉山弘和
- Organizer
  化学工学会第86年会
- Data Source
  KAKENHI-PROJECT-20K21102
[Presentation] Model-Based Assessment of Freezing Temperature Profiles for Human Induced Pluripotent Stem Cells2021
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-Oka, Hirokazu Sugiyama
- Organizer
  2020 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21102
[Presentation] 数値流体力学シミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討2021
- Author(s)
  林勇佑, Scholz Benedikt, 杉山弘和
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K21102
[Presentation] 連続生産を考慮した製法選択 Selection of production methods considering continuous manufacturing2020
- Author(s)
  杉山弘和
- Organizer
  連続生産の実現・推進を考える会特別講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Multiobjective dynamic optimization of slow freezing processes for human induced pluripotent stem cells by modeling intracontainer condition2020
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-Oka, Hirokazu Sugiyama
- Organizer
  The 30th European Symposium on Computer-Aided Process Engineering (ESCAPE-30)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21102
[Presentation] 医薬品製造プロセスにおけるAI活用2020
- Author(s)
  杉山弘和
- Organizer
  AI・IoT・ビッグデータ活用の基礎とプロセスへの実装
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 原薬製造におけるバッチ・フロー合成の選択支援手法2020
- Author(s)
  金俊佑, 米倉寛智, 渡邊健朗, 吉川覚, 中西勇夫, 杉山弘和
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 連続・バッチ方式を考慮した注射剤製造プロセスの設計手法2020
- Author(s)
  山田真弘, 吉岡泰之, 中西勇夫, 杉山弘和
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] ヒトiPS細胞の緩慢凍結における温度プロファイルの最適化シミュレーション2020
- Author(s)
  林勇佑, 堀口一樹, 紀ノ岡正博, 杉山弘和
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] プロセスの視点から見た過酸化水素除染：迅速性と連続性2020
- Author(s)
  杉山弘和
- Organizer
  第8回最新の医薬、再生医療に関するGMP、技術動向を考える会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Quantum chemistry and molecular dynamics simulations on cryoprotective agents for human stem cells2020
- Author(s)
  Yusuke Hayashi, Yuka Nakajima, Hirokazu Sugiyama
- Organizer
  The 9th Asian Symposium on Process Systems Engineering (9th PSE Asia)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21102
[Presentation] CFDシミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討2020
- Author(s)
  林勇佑, Scholz Benedikt, 杉山弘和
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 無菌製剤製造における過酸化水素除染プロセスのモデルベースト設計2020
- Author(s)
  藪田啓奨, 二村はるか, 川崎康司, 杉山弘和
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Model-based design of freezing temperature profile for human induced pluripotent stem cells2020
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
- Organizer
  The 57th Annual Meeting of the Society for Cryobiology (CRYO2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 数値流体力学シミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討2020
- Author(s)
  林勇佑, Scholz Benedikt, 杉山弘和
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Multiobjective dynamic optimization of slow freezing processes for human induced pluripotent stem cells by modeling intracontainer condition2020
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-Oka, Hirokazu Sugiyama
- Organizer
  The 30th European Symposium on Computer-Aided Process Engineering (ESCAPE-30)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Analysis of the effects of process parameters on start-up operation in continuous wet granulation2020
- Author(s)
  Matsunami Kensaku, Nopens Ingmar, Sugiyama Hirokazu, De Beer Thomas
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] シングルユース技術・連続生産を考慮したバイオ医薬品製造プロセスの俯瞰的設計2020
- Author(s)
  白畑春来, Badr Sara, 杉山弘和
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] ヒトiPS細胞の緩慢凍結における温度プロファイルの最適化シミュレーション2020
- Author(s)
  林勇佑, 堀口一樹, 紀ノ岡正博, 杉山弘和
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] ヒトiPS細胞の緩慢凍結における温度プロファイルの最適化シミュレーション2020
- Author(s)
  林勇佑, 堀口一樹, 紀ノ岡正博, 杉山弘和
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-20K21102
[Presentation] Holistic and model-based design of oral drug manufacturing processes considering uncertainty in clinical development2019
- Author(s)
  Kensaku Matsunami, Hirokazu Sugiyama
- Organizer
  The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Economic evaluation tool for holistic design of solid drug product manufacturing processes considering continuous technology2019
- Author(s)
  Kensaku Matsunami, Fabian Sternal, Keita Yaginuma, Shuichi Tanabe, Hiroshi Nakagawa, Hirokazu Sugiyama
- Organizer
  2019 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Model-based determination of lot-size in pharmaceutical injectable manufacturing2019
- Author(s)
  Masahiro Yamada, Sara Badr, Shouko Fukuda, Manabu Nakaya, Yasuyuki Yoshioka, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] バイオ医薬品注射剤製造における装置技術選択のためのオンライン支援ツール2019
- Author(s)
  白畑春来, 新納裕樹, 萩森秀太, Badr Sara, 杉山弘和
- Organizer
  化学工学会第84年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 製剤製造を対象とする多目的かつ実践的なプロセス設計手法の開発2019
- Author(s)
  杉山弘和
- Organizer
  第17回技術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Simulation-based design of slow freezing processes for human induced pluripotent stem cells considering intracontainer variation2019
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
- Organizer
  18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Alternative generation and evaluation using a design framework: Case study on drug substance manufacturing processes of biopharmaceuticals2019
- Author(s)
  Haruku Shirahata, Sara Badr, Hirokazu Sugiyama
- Organizer
  2019 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 連続生産とプロセス設計2019
- Author(s)
  杉山弘和
- Organizer
  第9回レギュラトリーサイエンス学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Data-driven predictive monitoring and operation support for change-over processes in biopharmaceutical drug product manufacturing2019
- Author(s)
  Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  2019 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation2019
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
- Organizer
  2019 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Roles of process systems engineering in the design and operation of pharmaceutical manufacturing processes2019
- Author(s)
  Hirokazu Sugiyama
- Organizer
  The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Dynamic modelling and simulation of Chinese hamster ovary (CHO) cell fermentation for advanced biopharmaceutical manufacturing2019
- Author(s)
  Haruku Shirahata, Samir Diab, Hirokazu Sugiyama, Dimitrios Gerogiorgis
- Organizer
  The 29th European Symposium on Computer-Aided Process Engineering (ESCAPE-29)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Process Systems Engineering for Pharmaceutical Process Design and Operation2019
- Author(s)
  Hirokazu Sugiyama
- Organizer
  3rd International Conference on Functional Materials and Chemical Engineering (ICFMCE-2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 連続生産を考慮した固形製剤製造プロセスの経済性評価2019
- Author(s)
  松並研作, 田邉修一, 柳沼啓太, 杉山弘和
- Organizer
  化学工学会第84年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 製薬プロセスシステム工学と意思決定支援2019
- Author(s)
  杉山弘和
- Organizer
  インターフェックスジャパンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Machine learning applications for predictive operation support in change-over processes of biopharmaceutical drug product manufacturing2019
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Continuous Manufacturing from Decision-Making Perspective2019
- Author(s)
  Hirokazu Sugiyama
- Organizer
  2019 ISPE Asia Pacific Pharmaceutical Manufacturing Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Freeze-thaw process design of induced pluripotent stem cells using white-box models2019
- Author(s)
  Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  The 29th European Symposium on Computer-Aided Process Engineering (ESCAPE-29)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Simultaneous design of process and scheduling for pharmaceutical decontamination2019
- Author(s)
  Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Hirokazu Sugiyama
- Organizer
  18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Data-driven predictive monitoring and operation support for decontamination processes in biopharmaceutical manufacturing2018
- Author(s)
  Zeberli Anicia, Badr Sara, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Data mining-based algorithm for pre-processing biopharmaceutical manufacturing records2018
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  13th International Symposium on Process Systems Engineering (PSE 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] バイオ医薬品製造における技術選択のオンライン支援ツール2018
- Author(s)
  白畑春来, 新納裕樹, 萩森秀太, Rizki Darmawan, Sara Badr, 杉山弘和
- Organizer
  MATLAB EXPO 2018 Japan
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Industrial scale experiments towards the development of process evaluation models for continuous pharmaceutical tablet manufacturing2018
- Author(s)
  Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  28th European Symposium on Computer Aided Process Engineering (ESCAPE-28)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Economic evaluation of batch and continuous manufacturing technologies for solid drug products during clinical development2018
- Author(s)
  Kensaku Matsunami, Shuichi Tanabe, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  13th International Symposium on Process Systems Engineering (PSE 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Data-driven real-time operation support for decontamination processes in biopharmaceutical drug product manufacturing2018
- Author(s)
  Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  2018 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品製造におけるシステムズ・アプローチの役割2018
- Author(s)
  杉山弘和
- Organizer
  医療薬学フォーラム2018・第26回クリニカルファーマシーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] ライフサイクルを考慮したリチウムイオン電池の安全設計支援手法2018
- Author(s)
  山西智紀, 天沢逸里, 杉山弘和, 平尾雅彦
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-15K12469
[Presentation] プロセス情報の統合利用による注射剤製造のロットサイズ決定2018
- Author(s)
  山田真弘, Badr Sara, 福田咲香, 中家学, 吉岡泰之, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] バイオ医薬品注射剤製造におけるシングルユース・マルチユース技術の選択支援モデル2018
- Author(s)
  杉山弘和, 白畑春来, Zuercher Philipp, Badr Sara
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Process systems engineering for pharmaceutical manufacturing2018
- Author(s)
  Hirokazu Sugiyama
- Organizer
  KIChE-SCEJ Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品製造のためのプロセスシステム工学2018
- Author(s)
  杉山弘和
- Organizer
  第7回医薬品製造に関する技術動向を考える会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Process modelling, simulation and optimisation for continuous biopharmaceutical manufacturing2018
- Author(s)
  Samir Diab, Haruku Shirahata, Hirokazu Sugiyama, Dimitrios I. Gerogiorgis
- Organizer
  2018 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Framework for data-driven process improvement and operations support in biopharmaceutical drug product manufacturing2018
- Author(s)
  Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Multi-stage and multi-objective design tool for process design in sterile filling of biopharmaceuticals2018
- Author(s)
  Haruku Shirahata, Philipp Zuercher, Sara Badr, Hirokazu Sugiyama
- Organizer
  2018 AIChE Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] バイオ医薬品の製造プロセス設計における意思決定支援2018
- Author(s)
  杉山弘和
- Organizer
  化学工学会関東支部バイオプロセス講演・見学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Quantitative analysis on the relevance of regulatory constraints in designing pharmaceutical manufacturing processes2018
- Author(s)
  Hirokazu Sugiyama, Yusuke Morikawa, Mai Matsuura, Menghe Xu
- Organizer
  13th International Symposium on Process Systems Engineering (PSE 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 実験計画法に基づく錠剤連続製造のプロセス評価モデル2018
- Author(s)
  松並研作, 長門琢也, 長谷川浩司, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Models for designing hydrogen peroxide decontamination processes in sterile drug product manufacturing2018
- Author(s)
  Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  28th European Symposium on Computer Aided Process Engineering (ESCAPE-28)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 意思決定の切り口から見た連続生産2018
- Author(s)
  杉山弘和
- Organizer
  ISPE日本本部第17回冬季大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] バイオ医薬品の製造プロセス設計における意思決定支援－品質と効率の両立－2018
- Author(s)
  杉山弘和
- Organizer
  国立医薬品食品衛生研究所特別講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Multilayer and multiobjective design platform for drug product manufacturing processes of biopharmaceuticals2018
- Author(s)
  Haruku Shirahata, Shant Dakessian, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  13th International Symposium on Process Systems Engineering (PSE 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 製薬プロセスシステム工学の最近の進捗2018
- Author(s)
  杉山弘和
- Organizer
  大阪大学細胞製造コトづくり講座
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品錠剤のバッチ・連続製造プロセスにおける製品品質評価2017
- Author(s)
  松並研作, 長門琢也, 長谷川浩司, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品製剤製造プロセスにおけるマテリアルロス低減手法2017
- Author(s)
  伊藤正晃, 秋本泰明, 高橋健二, 加藤義和, 菊地宣昭, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 経済性評価に基づく注射剤製造プロセスのロットサイズ決定手法2017
- Author(s)
  山田真弘, 吉岡泰之, 中家学, 福田咲香, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 製剤製造における装置技術情報を統合したプロセス合成2017
- Author(s)
  杉山弘和
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品製造におけるモデルベースト設計の役割2017
- Author(s)
  杉山弘和
- Organizer
  2017年ISPE日本本部年次大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品・再生医療製品の製造におけるモデルベースト設計2017
- Author(s)
  杉山弘和
- Organizer
  第16回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品製造の課題とプロセスシステム工学による解決のアプローチ2017
- Author(s)
  杉山弘和
- Organizer
  化学工学会開発型企業の会 2017年度第2回技術交流会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 臨床開発時における固形製剤製造プロセスの設計手法2017
- Author(s)
  松並研作, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Monte Carlo シミュレーションを用いた他家iPS細胞のワーキングセルバンク設計2017
- Author(s)
  塩唐松正樹, 紀ノ岡正博, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 連続製造を対象とするプロセスシステム工学研究2017
- Author(s)
  杉山弘和
- Organizer
  第25回静岡フォーラム・第50回研究交流セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] プロセス特性を考慮した原薬製造における環境・健康・安全リスク低減手法2017
- Author(s)
  福原祥平, 西舘修, 菊地真, 高橋美文, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Big data-platform for supporting design and operation of biopharmaceutical decontamination processes2017
- Author(s)
  Zeberli Anicia, Roedl Thomas, Knueppel Stephanie, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Risk evaluation models for the design of parenterals manufacturing processes2017
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  The 27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Application of computational fluid dynamics for equipment redesign in sterile manufacturing of biopharmaceuticals2017
- Author(s)
  Zeberli Anicia, Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] アクティビティモデリング手法IDEF0の基礎2017
- Author(s)
  杉山弘和
- Organizer
  産業技術総合研究所福島再生可能エネルギー研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Decision-support tools for biopharmaceutical manufacturing2017
- Author(s)
  Hirokazu Sugiyama
- Organizer
  化学工学会第83年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 電気自動車用リチウムイオン電池のリユース及びリサイクルにおける技術選択支援2017
- Author(s)
  阿部将宜、杉山弘和、平尾雅彦
- Organizer
  第12回日本LCA学会研究発表会
- Place of Presentation
  産業技術総合研究所つくばセンター（茨城県つくば市）
- Year and Date
  2017-03-01
- Data Source
  KAKENHI-PROJECT-15K12469
[Presentation] シングルユース・マルチユース技術の選択を考慮した注射剤製造プロセスの設計手法2017
- Author(s)
  白畑春来, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Data-driven approaches for process improvement and operation support in biopharmaceutical drug product manufacturing2017
- Author(s)
  Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品の連続生産を対象とするプロセスシステム工学研究2017
- Author(s)
  杉山弘和
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] バイオプロセスイノベーションと情報統合2017
- Author(s)
  杉山弘和
- Organizer
  INCHEM TOKYO 2017産学官マッチングフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] プロセス選択肢としての連続生産2017
- Author(s)
  杉山弘和
- Organizer
  ISPE日本本部第16回冬季大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品錠剤製造プロセスにおけるバッチ・連続技術の製品品質評価2017
- Author(s)
  松並研作, 長門琢也, 長谷川浩司, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Research needs and opportunities for process systems engineering in pharmaceutical manufacturing2017
- Author(s)
  Hiorkazu Sugiyama
- Organizer
  6th Conference on Emerging Energy & Process Technology 2017 (CONCEPT 2017)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 患者特性を考慮した残薬削減対策の選択支援手法2017
- Author(s)
  原田典和, 矢作尚久, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品・再生医療製品の製造におけるモデルベースト設計2017
- Author(s)
  杉山弘和
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター, 宮城県仙台市
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Process systems engineering approaches for drug product manufacturing: from tablets to injectables2017
- Author(s)
  Hirokazu Sugiyama, Kensaku Matsunami, Keisho Yabuta
- Organizer
  The 27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Integrated process performance assessment considering uncertainty in biopharmaceutical manufacturing operations2017
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  The 27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品・再生医療製品の製造におけるモデルベースト設計2017
- Author(s)
  杉山弘和
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品製造における過酸化水素を用いた除染プロセスの設計手法2017
- Author(s)
  藪田啓奨, 二村はるか, 川崎康司, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス, 東京都江東区
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] iPS細胞の産業化に向けた凍結・解凍プロセス設計2017
- Author(s)
  林勇佑, 紀ノ岡正博, 堀口一樹, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Pharma PSE 研究最前線～除染・シングルユース・連続製造～2017
- Author(s)
  杉山弘和
- Organizer
  第6回最新の医薬・医療に関するGMP・技術動向を考える会パイロットセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Large-scale experimental comparison of batch and continuous technologies for pharmaceutical tablet manufacturing2017
- Author(s)
  Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 医薬品製造における意思決定とスマート化～プロセス設計から継続的改善まで～2017
- Author(s)
  杉山弘和
- Organizer
  バレオコンエグゼクティブセミナー2017
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Pharma PSE: Developing Novel Design Methodologies for Pharmaceutical Manufacturing Processes2017
- Author(s)
  杉山弘和
- Organizer
  日本学術振興会プロセスシステム工学第143委員会平成29年度第3回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] 注射剤製造プロセスの多階層・多目的設計プラットフォーム2017
- Author(s)
  白畑春来, Shant Dakessian, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PROJECT-17H04964
[Presentation] Process model of sterile drug product manufacturing for yield enhancement2016
- Author(s)
  Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Multiobjective retrofitting methodology for manufacturing processes of active pharmaceutical ingredients considering environmental, health and safety risks2016
- Author(s)
  Hirokazu Sugiyama, Akiko Segawa, Satoshi Yoshikawa, Takayuki Toyama, Hayao Nakanishi, Emi Kikuchi-Uehara, Masahiko Hirao
- Organizer
  26th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Bernardin Congress Centre, Portoroz, Slovenia
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Conducting process systems engineering research on pharmaceutical manufacturing2016
- Author(s)
  Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品製造を対象とするプロセスシステム工学2016
- Author(s)
  杉山弘和
- Organizer
  第22回流動化・粒子プロセッシングシンポジウム
- Place of Presentation
  東京大学生産技術研究所, 東京都目黒区
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] バッチ・連続技術を考慮した医薬品錠剤製造のプロセスシステム工学的アプローチ2016
- Author(s)
  松並研作, 宮野拓也, 荒井宏明, 中川弘司, 平尾雅彦, 杉山弘和
- Organizer
  第22回流動化・粒子プロセッシングシンポジウム
- Place of Presentation
  東京大学生産技術研究所, 東京都目黒区
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Product loss reduction in batch manufacturing of sterile drug products2016
- Author(s)
  Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Product loss reduction in batch manufacturing of sterile drug products2016
- Author(s)
  Masaaki Ito, Yasuyuki Yoshioka, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品連続製造を対象とするプロセスシステム工学研究2016
- Author(s)
  杉山弘和, 松並研作
- Organizer
  化学工学会第48回秋季大会
- Place of Presentation
  徳島大学常三島キャンパス, 徳島県徳島市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Process performance assessment based on stochastic simulation in sterile drug product manufacturing2016
- Author(s)
  Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  化学工学会第48回秋季大会
- Place of Presentation
  徳島大学常三島キャンパス, 徳島県徳島市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品製造プロセスの設計問題2016
- Author(s)
  杉山弘和
- Organizer
  化学工学会第81年会
- Place of Presentation
  北海道大学札幌キャンパス, 北海道札幌市北区
- Year and Date
  2016-03-13
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Design problem of pharmaceutical manufacturing processes2016
- Author(s)
  Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2016
- Place of Presentation
  Hilton San Francisco Union Square, San Francisco, U.S.A
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品原薬製造における溶媒回収プロセス設計2016
- Author(s)
  徐夢荷, 松浦麻衣, 森川裕介, 杉山弘和
- Organizer
  化学工学会第81年会
- Place of Presentation
  関西大学千里山キャンパス, 大阪府吹田市
- Year and Date
  2016-03-13
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] バイオプロセスイノベーションにおける統合化工学の役割2016
- Author(s)
  杉山弘和
- Organizer
  化学工学会第48回秋季大会
- Place of Presentation
  徳島大学常三島キャンパス, 徳島県徳島市
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Pharma PSE研究の今後とCOPとしての展開2016
- Author(s)
  杉山弘和
- Organizer
  2016年ISPE日本本部年次大会
- Place of Presentation
  タワーホール船堀, 東京都江戸川区
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Process model of sterile drug product manufacturing for yield enhancement2016
- Author(s)
  Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Design method for pharmaceutical tablet production considering batch & continuous technologies2016
- Author(s)
  Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Creating hybrid-model-based simulation environment for sterile drug product manufacturing2016
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Conducting process systems engineering research on pharmaceutical Mmnufacturing2016
- Author(s)
  Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Design method for pharmaceutical tablet production considering batch & continuous technologies2016
- Author(s)
  Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 注射剤製造プロセス設計のためのリスク評価モデル2016
- Author(s)
  白畑春来, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第48回秋季大会
- Place of Presentation
  徳島大学常三島キャンパス, 徳島県徳島市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Hybrid approach for improving drug product manufacturing efficiency2016
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Biopharmaceutical process optimization: needs and benefits of numerical simulation approaches2016
- Author(s)
  Casola Gioele, Siegmund Christian, Mattern Markus, Sugiyama Hirokazu
- Organizer
  第22回流動化・粒子プロセッシングシンポジウム
- Place of Presentation
  東京大学生産技術研究所, 東京都目黒区
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Developing process models of hydrogen peroxide decontamination in pharmaceutical manufacturing2016
- Author(s)
  Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2016
- Place of Presentation
  Hilton San Francisco Union Square, San Francisco, U.S.A
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Mid-term scheduling model based on state-task-network considering plant specific constraints in pharmaceutical manufacturing2016
- Author(s)
  Gioele Casola, Lukas Gallus Eberle, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  26th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Bernardin Congress Centre, Portoroz, Slovenia
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Hybrid approach for improving drug product manufacturing efficiency2016
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Monte carlo simulation-based method for process performance assessment in sterile manufacturing of biopharmaceuticals2016
- Author(s)
  Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2016
- Place of Presentation
  Hilton San Francisco Union Square, San Francisco, U.S.A
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Selection support method of single-use vs. multi-use technologies in sterile drug product manufacturing2016
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  7th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia 2016)
- Place of Presentation
  Ito International Research Center, Bunkyo-ku, Tokyo, Japan
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Selection support methodology between batch and continuous technologies for pharmaceutical tablet manufacturing processes2016
- Author(s)
  Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2016
- Place of Presentation
  Hilton San Francisco Union Square, San Francisco, U.S.A
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] バッチ・連続技術の選択を考慮した医薬品錠剤製造プロセスの設計手法2016
- Author(s)
  松並研作, 宮野拓也, 新井宏明, 中川弘司, 平尾雅彦, 杉山弘和
- Organizer
  化学工学会第81年会
- Place of Presentation
  関西大学千里山キャンパス, 大阪府吹田市
- Year and Date
  2016-03-13
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Systematic retrofitting methodology for pharmaceutical drug purification processes2015
- Author(s)
  Gioele Casola, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2015
- Place of Presentation
  Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Systematic retrofitting methodology for recrystallization of thermally unstable active pharmaceutical ingredients2015
- Author(s)
  Gioele Casola, Hirokazu Sugiyama, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao
- Organizer
  12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Improving yield of drug product manufacturing with hybrid approach2015
- Author(s)
  Lukas Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Organizer
  AIChE annual meeting 2015
- Place of Presentation
  Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 無菌製剤製造における収率改善のためのプロセスモデル構築2015
- Author(s)
  杉山弘和
- Organizer
  化学工学会第47年回秋季大会
- Place of Presentation
  北海道大学札幌キャンパス, 北海道札幌市北区
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Optimal scheduling of liquid drug product manufacturing2015
- Author(s)
  Lukas Gallus Eberle, Elisabet Capón-Garcia, Martin Senninger, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Organizer
  12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Systems engineering approaches for designing pharmaceutical manufacturing processes2015
- Author(s)
  Hirokazu Sugiyama
- Organizer
  Pharma Process Forum
- Place of Presentation
  Palau de Congressos, Barcelona, Spain
- Year and Date
  2015-10-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] The role of modeling, simulation and optimization approaches in the design of pharmaceutical production processes2015
- Author(s)
  Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2015
- Place of Presentation
  Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Systems engineering approaches for designing pharmaceutical manufacturing processes2015
- Author(s)
  Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama
- Organizer
  AIChE annual meeting 2015
- Place of Presentation
  Salt Palace Convention Center, Salt Lake City, Utah, U.S.A.
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Process-based method for reducing product losses in pharmaceutical manufacturing2015
- Author(s)
  Hirokazu Sugiyama, Masahiko Hirao
- Organizer
  12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Improving pharmaceutical batch production processes with data-based tiered approach2015
- Author(s)
  Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Organizer
  12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Data-Based Tiered Approach for Improving Pharmaceutical Batch Production Processes2014
- Author(s)
  Lukas Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbuehler
- Organizer
  24th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Budapest, Hungary
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] Applying Process Systems Engineering in Pharmaceutical Industry: A New Paradigm2014
- Author(s)
  Sugiyama Hirokazu
- Organizer
  化学工学会第79年会
- Place of Presentation
  岐阜大学柳戸キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] Integration Framework for Improving Quality and Cost-Effectiveness in Pharmaceutical Production Processes2014
- Author(s)
  Hirokazu Sugiyama, Masahiko Hirao
- Organizer
  24th European Symposium on Computer Aided Process Engineering
- Place of Presentation
  Budapest, Hungary
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 医薬品製造プロセスの継続的改善を支援する統合化アプローチ2014
- Author(s)
  杉山弘和
- Organizer
  インターフェックスジャパン専門技術セミナー
- Place of Presentation
  東京ビッグサイト
- Invited
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 医薬品製造を対象とするプロセス改善支援手法2014
- Author(s)
  伊藤正晃、杉山弘和、平尾雅彦
- Organizer
  化学工学会第79年会
- Place of Presentation
  岐阜大学柳戸キャンパス
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 医薬品製造の品質・生産性向上にむけたプロセスベースト・アプローチ2014
- Author(s)
  杉山弘和、伊藤正晃、平尾雅彦
- Organizer
  化学工学会第79年会
- Place of Presentation
  岐阜大学柳戸キャンパス
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 医薬品製造プロセスの品質・生産性向上に向けた統合化工学2013
- Author(s)
  杉山弘和
- Organizer
  INCHEM TOKYO 2013
- Place of Presentation
  東京ビッグサイト
- Invited
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 石油精製への影響を考慮したバイオマス利活用システム設計2013
- Author(s)
  Maghfuri Baharuddin, 杉山弘和, 菊池康紀, 平尾雅彦
- Organizer
  化学工学会第45回秋季大会
- Place of Presentation
  岡山大学(岡山)
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PROJECT-23360404
[Presentation] 医薬品製造プロセスの品質・生産性向上に向けた統合化工学2013
- Author(s)
  杉山弘和
- Organizer
  化学工学会第45回秋季大会
- Place of Presentation
  岡山大学津島（東）キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 石油精製への影響を考慮したバイオマス利活用システム設計2013
- Author(s)
  Maghfuri Baharuddin, 杉山弘和, 菊池康紀, 平尾雅彦
- Organizer
  化学工学会第45回秋季大会
- Place of Presentation
  岡山大学（岡山）
- Data Source
  KAKENHI-PROJECT-23360404
[Presentation] 医薬品原薬精製を対象とするシミュレーション技術を用いたプロセス改善手法
- Author(s)
  Casola Gioele, 杉山弘和, 吉川覚, 中西勇夫, 平尾雅彦
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品製造バッチプロセスを対象とする数理モデル構築
- Author(s)
  藪田啓奨, 杉山弘和, 平尾雅彦
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品製造を対象とするモデル化・シミュレーション・最適化研究
- Author(s)
  杉山弘和
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品原薬製造における多目的評価に基づく環境・健康・安全リスク低減手法
- Author(s)
  瀬川晶子, 杉山弘和, 吉川覚, 遠山貴之, 中西勇夫, 平尾雅彦
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 医薬品産業における品質・生産性向上に向けた新たな挑戦
- Author(s)
  杉山弘和
- Organizer
  2013年度ISPE日本本部冬季大会
- Place of Presentation
  メルパルク大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] 医薬品製造におけるプロセスシステム工学の新展開
- Author(s)
  杉山弘和
- Organizer
  日本学術振興会プロセスシステム工学第143委員会H25年度第5回研究会
- Place of Presentation
  キャンパスイノベーションセンター（CIC）東京
- Invited
- Data Source
  KAKENHI-PROJECT-25889016
[Presentation] モンテカルロ法を用いた医薬品製造プロセスのリードタイム改善
- Author(s)
  杉山弘和, Eberle Lukas, Schmidt Rainer
- Organizer
  化学工学会第46回秋季大会
- Place of Presentation
  九州大学伊都キャンパス（福岡県福岡市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 注射剤製造におけるシングルユース・マルチユース技術の選択支援手法
- Author(s)
  白畑春来, 杉山弘和, 平尾雅彦
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] 品質・経済性を考慮した医薬品原料使用プロセスの多目的設計手法
- Author(s)
  飯田剛之, 太田耕右, 哘崎智仁, 杉山弘和
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26820343
[Presentation] Integration approach for realizing superior production processes in the pharmaceutical industry
- Author(s)
  Hirokazu Sugiyama
- Organizer
  Sicherheit und Umweltschutz in der Chemie, Seminarreihe Fruehjahrssemester 2014
- Place of Presentation
  ETH Zurich, Switzerland
- Invited
- Data Source
  KAKENHI-PROJECT-25889016

1. HIRAO Masahiko (80282573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. UEHARA Emi (10648132)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. NAKATANI Jun (40436522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KIKUCHI Yasunori (70545649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. AMASAWA ERI (80804989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 矢作尚久 (30365431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 太田誠一 (40723284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 加納学 (30263114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 金尚弘 (60735504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 紀ノ岡正博 (40234314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. Hungerbuehler Konrad

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results

Sugiyama Hirokazu 杉山 弘和

SUGIYAMA Hirokazu 杉山 弘和

Research Projects

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Co-Researchers

Development of rapid manufacturing support system for anti-pandemic drugsPrincipal Investigator

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Development of innovative management strategy for pharmaceutical continuous manufacturing processes

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Multiscale design platform for innovating freezing processes of iPS cellsPrincipal Investigator

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Development of innovative process design methodology for pharmaceutical manufacturing and tool implementationPrincipal Investigator

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Safety design method of Lithium ion battery using systems approach

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Development of multiobjective process design method for quality and productivity improvement in pharmaceutical manufacturingPrincipal Investigator

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製薬プロセスの品質・生産性向上にむけた意思決定支援手法の開発Principal Investigator

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Material flow model for the evaluation of recycling considering relations between different materials

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[Book] 固形剤の連続製造プロセス設計と経済性評価2020

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[Book] "連続生産を対象とするプロセスシステム工学研究" 固形製剤とバイオ原薬の連続生産2019

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[Book] 注射剤製造における無菌性保証・バリデーションと異物低減ノウハウ・検査事例2016

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[Book] 抗体医薬における細胞構築・培養・ダウンストリームのすべて 第8編第1章 医薬品生産における統合化工学とは2015

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[Book] “医薬品生産における統合化工学とは” 抗体医薬品における細胞構築・培養・ダウンストリームのすべて, 大政健史（編）2015

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Sugiyama Hirokazu 杉山弘和

SUGIYAMA Hirokazu 杉山弘和

[Book] 抗体医薬における細胞構築・培養・ダウンストリームのすべて第8編第1章医薬品生産における統合化工学とは2015