Zhang Yizhou ZHANG YIZHOU

Researcher Number	70711117
Other IDs
Affiliation (based on the past Project Information) *help	2017: 広島大学, 医歯薬保健学研究科(医), 研究員 2015 – 2016: 広島大学, 医歯薬保健学研究院(医), 研究員 2014: 広島大学, 医歯薬保健学研究院, 研究員
Review Section/Research Field	Principal Investigator Gastroenterology / General medical chemistry
Keywords	Principal Investigator 小胞体ストレス / BBF2H7 / ゲノム編集 / cancer targeted therapy / CRISPR-CAS9 / ER stress response / 分子標的治療 / 肝細胞癌 / 分子標的癌治療 / 小胞体ストレス応答 / がん分子標的治療 / 抗体医薬

Explore new therapies targeting endoplasmic reticulumn stress response for Hepatocellular CarcinomaPrincipal Investigator
- Principal Investigator
  
  Zhang Yizhou
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University
Analysis of the mechanism of cell proliferation regulated by the endoplasmic reticulum stress sensor BBF2H7Principal Investigator
- Principal Investigator
  
  Zhang Yizhou
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.2018
- Author(s)
  Masuda K, Ono A, Aikata H, Kawaoka T, Nelson Hayes C, Teraoka Y, Daijo K, Nakamura-Inagaki Y, Morio K, Fujino H, Kan H, Uchida T, Masaki K, Kobayashi T, Nakahara T, Makokha GN, Zhang Y, Nagaoki Y, Miki D, Tsuge M, Hiramatsu A, Imamura M, Abe-Chayama H, Kawakami Y, Ochi H, Chayama K.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 53 Issue: 1 Pages: 107-118
- DOI
  10.1007/s00535-017-1348-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09446, KAKENHI-PROJECT-16K19346
[Journal Article] The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients2017
- Author(s)
  Kurihara M, Tsuge M, Murakami E, Mori N, Ohishi W, Uchida T, Fujino H, Nakahara T, Abe-Chayama H, Kawaoka T, Miki D, Hiramatsu A, Imamura M, Kawakami Y, Aikata H, Ochi H, Zhang Y, Makokha GN, Hayes CN, Chayama K.
- Journal Title
  
  Antivir Ther
  
  Volume: Epub ahead of print Issue: 3 Pages: 239-248
- DOI
  10.3851/imp3196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19346
[Journal Article] Persistent loss of HBV markers in serum without cellular immunity by combination of PEG-IFN plus ETV therapy in humanized mice2017
- Author(s)
  Uchida T, Imamura M, Hayes CN, Hiraga N, Kan H, Tsuge M, Abe-Chayama H, Zhang Y, Makokha GN, Aikata H, Miki D, Ochi H, Ishida Y, Tateno C, Chayama K
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 61 Issue: 9
- DOI
  10.1128/aac.00725-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09427, KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-16K19346
[Journal Article] Early events in hepatitis B virus infection: From the cell surface to the nucleus.2016
- Author(s)
  Hayes CN, Zhang Y, Makokha GN, Hasan MZ, Omokoko MD, Chayama K.
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: Volume 31, Issue 2, Issue: 2 Pages: 302-309
- DOI
  10.1111/jgh.13175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860191, KAKENHI-PROJECT-15K15293
[Journal Article] Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection.2016
- Author(s)
  Tsuge M, Hiraga N, Uchida T, Kan H, Miyaki E, Masaki K, Ono A, Nakahara T, Abe-Chayama H, Zhang Y, Naswa MG, Kawaoka T, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Chayama K.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: In press Issue: 11 Pages: 1073-1080
- DOI
  10.1007/s00535-016-1189-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860191, KAKENHI-PROJECT-15K15293, KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-16K19346
[Journal Article] The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.2015
- Author(s)
  Honda Y, Takahashi S, Zhang Y, Ono A, Murakami E, Shi N, Kawaoka T, Miki D, Tsuge M, Hiraga N, Abe H, Ochi H, Imamura M, Aikata H, Chayama K.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 30 Issue: 3 Pages: 619-627
- DOI
  10.1111/jgh.12715
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-26860536, KAKENHI-PROJECT-26860191
[Journal Article] Chondrocyte Proliferation Regulated by Secreted Luminal Domain of ER Stress Transducer BBF2H7/CREB3L2.2014
- Author(s)
  Saito A, Kanemoto S, Zhang Y, Asada R, Hino K, Imaizumi K.
- Journal Title
  
  Molecular Cell
  
  Volume: 53 Issue: 1 Pages: 127-139
- DOI
  10.1016/j.molcel.2013.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-24659678, KAKENHI-PROJECT-24689058, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-25650069, KAKENHI-PROJECT-25861324, KAKENHI-PROJECT-26860191
[Presentation] New insights on the role of endoplasmic reticulum stress response in development of hepatocellular carcinoma2017
- Author(s)
  Yizhou Zhang, C Nelson Hayes, Tadahiko Yoshima, Masataka Tsuge, Hiromi Abe-Chayama, Kazuaki Chayama
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19346
[Presentation] Hepatocellular Carcinoma Promotion by Endoplasmic Reticulum Stress Transducer BBF2H7.2016
- Author(s)
  Yizhou Zhang, Nelson Hayes, Masataka Tsuge, Takuro Uchida, Daiki Miki, Hiromi Abe, Kazuaki Chayama
- Organizer
  AASLD 2016.
- Place of Presentation
  Boston, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19346
[Presentation] Involvement of Endoplasmic Reticulum Stress Transducer BBF2H7 in Hepatocellular Carcinoma Promotion.2015
- Author(s)
  Yizhou Zhang, Nelson Hayes, Masataka Tsuge, Nobuhiko Hiraga, Takuro Uchida, Daiki Miki, Hiromi Abe, Kazuaki Chayama.
- Organizer
  American Association for the Study of Liver Diseases (AASLD)
- Place of Presentation
  San Francisco, USA.
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860191
[Presentation] Hepatocellular Carcinoma Promotion by Endoplasmic Reticulum Stress Transducer BBF2H7.2015
- Author(s)
  YizhouZhang, Kazuaki Chayama
- Organizer
  World Conference on Interventional Oncology (WCIO)
- Place of Presentation
  New York, USA.
- Year and Date
  2015-05-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860191
[Presentation] Hepatocellular Carcinoma Promotion by Endoplasmic Reticulum Stress Transducer BBF2H7
- Author(s)
  Yizhou Zhang
- Organizer
  WCIO 2015
- Place of Presentation
  Hilton Hotel, New York, USA
- Year and Date
  2015-05-06 – 2015-05-09
- Data Source
  KAKENHI-PROJECT-26860191

1. IMAMURA Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. ABE Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 三木大樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Zhang Yizhou ZHANG YIZHOU

Research Projects

Research Products

Co-Researchers

Explore new therapies targeting endoplasmic reticulumn stress response for Hepatocellular CarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism of cell proliferation regulated by the endoplasmic reticulum stress sensor BBF2H7Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Persistent loss of HBV markers in serum without cellular immunity by combination of PEG-IFN plus ETV therapy in humanized mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Early events in hepatitis B virus infection: From the cell surface to the nucleus.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chondrocyte Proliferation Regulated by Secreted Luminal Domain of ER Stress Transducer BBF2H7/CREB3L2.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] New insights on the role of endoplasmic reticulum stress response in development of hepatocellular carcinoma2017

Author(s)

Organizer

Data Source

[Presentation] Hepatocellular Carcinoma Promotion by Endoplasmic Reticulum Stress Transducer BBF2H7.2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Involvement of Endoplasmic Reticulum Stress Transducer BBF2H7 in Hepatocellular Carcinoma Promotion.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hepatocellular Carcinoma Promotion by Endoplasmic Reticulum Stress Transducer BBF2H7.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hepatocellular Carcinoma Promotion by Endoplasmic Reticulum Stress Transducer BBF2H7

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source