Sugiyama Ryuichi 杉山隆一

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SUGIYAMA Ryuichi 杉山隆一

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Researcher Number	70714476
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所インフルエンザ研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2016 – 2017: 国立感染症研究所, ウイルス第二部, 研究員 2015: 横浜市立大学, 医学(系)研究科(研究院), 特任助教 2014: 国立感染症研究所, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Virology
Keywords	Principal Investigator 薬剤感受性 / インターフェロン / NS5A / C型肝炎ウイルス

Elucidation of the effect of HCV propagationa and IFN sensitivity by amino acid substitution in interferon sensitivity-determining region.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Ryuichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
  Yokohama City University

All 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Evaluation of Heating Conditions for Inactivation of Hepatitis E Virus Genotypes 3 and 4.2018
- Author(s)
  IMAGAWA T, SUGIYAMA R, SHIOTA T, LI TC, YOSHIZAKI S, WAKITA T, AND ISHII K.
- Journal Title
  
  Journal of Food Protection
  
  Volume: 81(6) Issue: 6 Pages: 947-952
- DOI
  10.4315/0362-028x.jfp-17-290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08090, KAKENHI-PROJECT-15K19118, KAKENHI-PROJECT-26860309, KAKENHI-PROJECT-16K08825
[Journal Article] Resistance mutations of hepatitis B virus in entecavir-refractory patients2017
- Author(s)
  Yamada Norie、Sugiyama Ryuichi、Nitta Sayuri、Murayama Asako、Kobayashi Minoru、Okuse Chiaki、Suzuki Michihiro、Yasuda Kiyomi、Yotsuyanagi Hiroshi、Moriya Kyoji、Koike Kazuhiko、Wakita Takaji、Kato Takanobu
- Journal Title
  
  Hepatology Communications
  
  Volume: 1 Issue: 2 Pages: 110-121
- DOI
  10.1002/hep4.1022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860309
[Journal Article] Interferon sensitivity-determining region of hepatitis C virus influences virus production and interferon signaling2017
- Author(s)
  Sugiyama R., Murayama A., Nitta S., Yamada N., Tasaka-Fujita M., Masaki T., Aly H. H., Shiina M., Ryo A., Ishii K., Wakita T. and Kato T.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 5 Pages: 5627-5640
- DOI
  10.18632/oncotarget.23562
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08825, KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-26860309, KAKENHI-PROJECT-18F18098
[Journal Article] ATP1B3 Modulates the Restriction of HIV-1 Production and NF-κB Activation by BST-2.2016
- Author(s)
  Hironori Nishitsuji, Ryuichi Sugiyama, Makoto Abe and Hiroshi Takaku.
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 (9) Issue: 9 Pages: 4754-4762
- DOI
  10.1074/jbc.m115.679357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860309
[Journal Article] Effects of resistance-associated NS5A mutations in hepatitis C virus on viral production and susceptibility to antiviral reagents.2016
- Author(s)
  Nitta S, Asahina Y, Matsuda M, Yamada N, Sugiyama R, Masaki T, Suzuki R, Kato N, Watanabe M, Wakita T, Kato T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34652-34652
- DOI
  10.1038/srep34652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-26860309
[Journal Article] ZNF10 inhibits HIV-1 LTR activity through interaction with NF-κB and Sp1 binding motifs.2015
- Author(s)
  Hironori Nishitsuji, Leila Sawada, Ryuichi Sugiyama and Hiroshi Takaku.
- Journal Title
  
  FEBS Lett.
  
  Volume: 589 Issue: 15 Pages: 2019-2025
- DOI
  10.1016/j.febslet.2015.06.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860309
[Journal Article] Amino acid polymorphisms in hepatitis C virus core affect infectious virus production and major histocompatibility complex class I molecule expression2015
- Author(s)
  Tasaka-Fujita M, Sugiyama N, Kang W, Masaki T, Murayama A, Yamada N, Sugiyama R, Tsukuda S, Watashi K, Asahina Y, Sakamoto N, Wakita T, Shin EC, Kato T
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 13994-14002
- DOI
  10.1038/srep13994
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-26860309, KAKENHI-PLANNED-24115003, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-25293169
[Journal Article] A new role for PGA1 in inhibiting hepatitis C virus-IRES-mediated translation by targeting viral translation factors.2015
- Author(s)
  Tsukimoto A, Sugiyama R, Abe M, Nishitsuji H, Shimizu Y, Shimotohno K, Kawai G, Takaku H.
- Journal Title
  
  Antiviral Res
  
  Volume: 117 Pages: 1-9
- DOI
  10.1016/j.antiviral.2015.01.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590557, KAKENHI-PROJECT-26860309
[Presentation] E型肝炎ウイルスに対する熱不活化条件の検討2017
- Author(s)
  杉山隆一，今川稔文，塩田智之，李天成，吉崎佐矢香，脇田隆字，石井孝司．
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-26860309
[Presentation] Amino acid substitutions in IFN sensitivity-determining region of HCV-NS5A affect infectious virus production and ISG induction.2016
- Author(s)
  Ryuichi Sugiyama, Nao Sugiyama, Asako Murayama, Megumi Tasaka-Fujita, Norie Yamada, Sayuri Nitta, Takahiro Masaki, Koji Ishii, Akihide Ryo, Takaji Wakita, Takanobu Kato.
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Kyoto, Japan.
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860309
[Presentation] Amino acid substitutions in ISDR of HCV-NS5A affect infectious virus production and ISG induction.2016
- Author(s)
  Ryuichi Sugiyama, Nao Sugiyama, Asako Murayama, Megumi Tasaka-Fujita, Norie Yamada, Sayuri Nitta, Takahiro Masaki, Akihide Ryo, Takaji Wakita, Takanobu Kato.
- Organizer
  25th Conference of the Asian Pacific Association for the Study of the Libber
- Place of Presentation
  グランドプリンスホテル新高輪 (東京都港区)
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860309
[Presentation] NS5A-ISDRアミノ酸変異によるHCV増殖およびIFN感受性への影響.
- Author(s)
  杉山隆一，杉山奈央，村山麻子，藤田めぐみ，山田典栄，新田沙由梨，脇田隆字，加藤孝宣.
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26860309
[Presentation] NS5A-ISDRアミノ酸変異がHCV増殖に与える影響の解析.
- Author(s)
  杉山隆一，杉山奈央，村山麻子，藤田めぐみ，山田典栄，脇田隆字，加藤孝宣.
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  山梨
- Year and Date
  2014-05-07 – 2014-05-09
- Data Source
  KAKENHI-PROJECT-26860309
[Presentation] Elucidation of the effect of HCV propagation by amino acid substitution in interferon sensitivity-determining region.
- Author(s)
  Sugiyama R, Sugiyaam N, Murayama A, Tasaka-Fujita M, Masaki T, Wakita T, Kato T.
- Organizer
  21th International Symposium on Hepatitis C virus and Related Viruses.
- Place of Presentation
  Banff, Cnada.
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-26860309

1. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. ABE Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 李天成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 加藤宣之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 高久洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 石井孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugiyama Ryuichi 杉山 隆一

SUGIYAMA Ryuichi 杉山 隆一

Research Projects

Research Products

Co-Researchers

Elucidation of the effect of HCV propagationa and IFN sensitivity by amino acid substitution in interferon sensitivity-determining region.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Evaluation of Heating Conditions for Inactivation of Hepatitis E Virus Genotypes 3 and 4.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Resistance mutations of hepatitis B virus in entecavir-refractory patients2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interferon sensitivity-determining region of hepatitis C virus influences virus production and interferon signaling2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ATP1B3 Modulates the Restriction of HIV-1 Production and NF-κB Activation by BST-2.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of resistance-associated NS5A mutations in hepatitis C virus on viral production and susceptibility to antiviral reagents.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ZNF10 inhibits HIV-1 LTR activity through interaction with NF-κB and Sp1 binding motifs.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Amino acid polymorphisms in hepatitis C virus core affect infectious virus production and major histocompatibility complex class I molecule expression2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A new role for PGA1 in inhibiting hepatitis C virus-IRES-mediated translation by targeting viral translation factors.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] E型肝炎ウイルスに対する熱不活化条件の検討2017

Author(s)

Organizer

Data Source

[Presentation] Amino acid substitutions in IFN sensitivity-determining region of HCV-NS5A affect infectious virus production and ISG induction.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Amino acid substitutions in ISDR of HCV-NS5A affect infectious virus production and ISG induction.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] NS5A-ISDRアミノ酸変異によるHCV増殖およびIFN感受性への影響.

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] NS5A-ISDRアミノ酸変異がHCV増殖に与える影響の解析.

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Elucidation of the effect of HCV propagation by amino acid substitution in interferon sensitivity-determining region.

Sugiyama Ryuichi 杉山隆一

SUGIYAMA Ryuichi 杉山隆一