Hatanaka Yuki 畑中勇輝

Researcher Number	70719450
Other IDs
Affiliation (Current)	2025: 大阪大学, 微生物病研究所, 助教
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤) 2015 – 2016: 国立研究開発法人理化学研究所, バイオリソースセンター, 特別研究員
Review Section/Research Field	Principal Investigator 0702:Biology at cellular to organismal levels, and related fields / Developmental biology
Keywords	Principal Investigator ヒストン修飾 / 精子形成 / エピジェネティクス / 5mCの酸化 / エピゲノム / エピジェネティックリプログラミング / DNA脱メチル化 / ES細胞 / 受精卵

精子形成過程における次世代に必要なエピジェネティクス機構の解明Principal Investigator
- Principal Investigator
  
  畑中勇輝
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0702:Biology at cellular to organismal levels, and related fields
- Research Institution
  Osaka University
Functional analysis of newly identified DNA demethylation factors in mouse ES cells and its application to somatic cell reprogrammingPrincipal Investigator
- Principal Investigator
  
  Hatanaka Yuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Institute of Physical and Chemical Research

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene2017
- Author(s)
  Michiko Hirose, Ayumi Hasegawa, Keiji Mochida, Shogo Matoba, Yuki Hatanaka, Kimiko Inoue, Tatsuhiko Goto, Hideki Kaneda, Ikuko Yamada, Tamio Furuse, Kuniya Abe, Yoshihisa Uenoyama, Hiroko Tsukamura, Shigeharu Wakana, Arata Honda, and Atsuo Ogura
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 42476-42476
- DOI
  10.1038/srep42476
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04286, KAKENHI-PUBLICLY-16H01225, KAKENHI-PLANNED-25112009, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-26250025, KAKENHI-PROJECT-26252046, KAKENHI-PROJECT-16H04687, KAKENHI-PROJECT-16H06146, KAKENHI-PROJECT-15K18545, KAKENHI-PROJECT-16K14644, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-17J00058, KAKENHI-PROJECT-15K06816
[Journal Article] The rodent-specific microRNA cluster within the Sfmbt2 gene is imprinted and essential for placental development.2017
- Author(s)
  Inoue K, Hirose M, Inoue H, Hatanaka Y, Honda A, Hasegawa A, Mochida K, Ogura A.
- Journal Title
  
  Cell Reports
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18545
[Journal Article] Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells2016
- Author(s)
  Inoue H, Ogonuki N, Hirose M, Hatanaka Y, Matoba S, Chuma S, Kobayashi K, Wakana S, Noguchi J, Inoue K, Tanemura K, *Ogura A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 478 Issue: 2 Pages: 592-8
- DOI
  10.1016/j.bbrc.2016.07.109
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25112004, KAKENHI-PLANNED-25112009, KAKENHI-PROJECT-16H04687, KAKENHI-PROJECT-16H06146, KAKENHI-PROJECT-26430100, KAKENHI-PROJECT-15K18545, KAKENHI-ORGANIZER-25112001
[Journal Article] Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposon.2015
- Author(s)
  Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodam E, Ohkawa Y, Tsukada Y, Ogura A.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 112 Issue: 47 Pages: 14641-14646
- DOI
  10.1073/pnas.1512775112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430100, KAKENHI-PROJECT-15K18545, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112008, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25670255, KAKENHI-PROJECT-26290064
[Presentation] Histone H3R17me2a mark recruits Tet3 to initiate active DNA demethylation in mouse zygotes2016
- Author(s)
  Hatanaka Y, Shimizu N, Morita K, Satoh M, Honda A, Hirose M, Kamimura S, Ogonuki N, Nakamura N, Inoue K, Hosoi Y, Nakano T, Matsumoto K, Ogura A.
- Organizer
  Mouse Genetics 2016
- Place of Presentation
  Florida, USA
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18545
[Presentation] マウス受精卵における能動的DNA脱メチル化制御因子の役割2016
- Author(s)
  畑中勇輝, 越後貫成美, 廣瀬美智子, 本多新, 井上貴美子, 松本和也,　小倉淳郎
- Organizer
  第109回日本繁殖生物学会
- Place of Presentation
  麻布大学獣医学部 (神奈川県相模原市)
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-15K18545
[Presentation] 着床前胚においてヒストンシャペロンCAF-1 は抑制性ヒストン修飾を調節することでレトロトランスポゾン抑制に機能する。2015
- Author(s)
  畑中勇輝，井上貴美子，及川真実，上村悟氏，越後貫成美，児玉栄一，大川恭行，束田裕一，小倉淳郎
- Organizer
  第38回日本分子生物学会大会
- Place of Presentation
  神戸ポートアイランド (神戸)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18545
[Presentation] 受精卵における能動的DNA脱メチル化機構2015
- Author(s)
  畑中勇輝
- Organizer
  第60回日本生殖医学会学術講演会
- Place of Presentation
  パシフィコ横浜 (横浜)
- Year and Date
  2015-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-15K18545
[Presentation] Histone H3R17me2a Mark Recruits Tet3 to Initiate Active DNA Demethylation in Mouse Zygotes2015
- Author(s)
  Hatanaka Y, Shimizu N, Morita K, Satoh M, Honda A, Hirose M, Kamimura S, Ogonuki N, Nakamura T, Inoue K, Hosoi Y, Nakano T, Matsumoto K, Ogura A
- Organizer
  THE 40th NAITO CONFERENCE “Epigenetics―From Histone Code to Therapeutic Strategy”
- Place of Presentation
  シャトレーゼ　ガトーキングダム　サッポロ（北海道）
- Year and Date
  2015-09-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18545

1. 本多新

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 小倉淳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 越後貫成美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 中馬新一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatanaka Yuki 畑中 勇輝

Research Projects

Research Products

Co-Researchers

精子形成過程における次世代に必要なエピジェネティクス機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of newly identified DNA demethylation factors in mouse ES cells and its application to somatic cell reprogrammingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The rodent-specific microRNA cluster within the Sfmbt2 gene is imprinted and essential for placental development.2017

Author(s)

Journal Title

Data Source

[Journal Article] Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposon.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Histone H3R17me2a mark recruits Tet3 to initiate active DNA demethylation in mouse zygotes2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウス受精卵における能動的DNA脱メチル化制御因子の役割2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 着床前胚においてヒストンシャペロンCAF-1 は抑制性ヒストン修飾を調節することでレトロトランスポゾン抑制に機能する。2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 受精卵における能動的DNA脱メチル化機構2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Histone H3R17me2a Mark Recruits Tet3 to Initiate Active DNA Demethylation in Mouse Zygotes2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Hatanaka Yuki 畑中勇輝