OKAZAKI SATOSHI 岡崎賢志

… Alternative Names

OKAZAKI Satoshi 岡崎賢志

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Researcher Number	70722867
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 神戸大学, 医学部附属病院, 助教 2016 – 2018: 神戸大学, 医学部附属病院, 医員 2015: 神戸大学, 医学(系)研究科(研究院), 医員
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science
Keywords	Principal Investigator iPS細胞 / アストロサイト / MIF / 統合失調症 / 神経幹細胞 / ニューロン / SNP / エピジェネティック年齢 / 低酸素 / HIF … More / ES細胞 / ヒストンアセチル化 / クロザピン / 神経前駆細胞 / 死後脳 / マイクロサテライト Less

Epigenetic pathomechanisms of accelerated aging in schizophreniaPrincipal Investigator
- Principal Investigator
  
  岡崎賢志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kobe University
Molecular mechanisms linking hypoxia exposure and schizophrenia with a focus on MIF.Principal Investigator
- Principal Investigator
  
  Okazaki Satoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kobe University
Molecular pathology of schizophrenia and novel mechanisms of antipsychotics from the perspective of MIFPrincipal Investigator
- Principal Investigator
  
  Okazaki Satoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kobe University
The role of macrophage migration inhibitory factor (MIF) in the neuroimmunological hypothesis of schizophreniaPrincipal Investigator
- Principal Investigator
  
  OKAZAKI Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Association study of a single nucleotide polymorphism in the hypoxia response element of the macrophage migration inhibitory factor gene promoter with suicide completers in the Japanese population2024
- Author(s)
  Shirai Toshiyuki、Okazaki Satoshi、Tanifuji Takaki、Otsuka Ikuo、Miyachi Masao、Okada Shohei、Shindo Ryota、Horai Tadasu、Mouri Kentaro、Takahashi Motonori、Kondo Takeshi、Ueno Yasuhiro、Hishimoto Akitoyo
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 44 Issue: 1 Pages: 262-266
- DOI
  10.1002/npr2.12410
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K07545, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Epigenome‐wide association study on methamphetamine dependence2024
- Author(s)
  Shirai Toshiyuki、Okazaki Satoshi、Tanifuji Takaki、Otsuka Ikuo、Horai Tadasu、Mouri Kentaro、Takemura Yukihiro、Aso Katsuro、Yamamoto Noriya、Hishimoto Akitoyo
- Journal Title
  
  Addiction Biology
  
  Volume: 29 Issue: 3
- DOI
  10.1111/adb.13383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K07545, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia2024
- Author(s)
  Kogure M, Kanahara N, MIyazawa A, Shiko Y, Otsuka I, Matsuyama K, Takase M, Kimura M, Kimura H, Ota K, Idemoto K, Tamura M, Oda Y, Yoshida T, Okazaki S, Yamasaki F, Nakata Y, Watanabe Y, Niitsu T, Hishimoto A, Iyo M.
- Journal Title
  
  Front Psychiatry
  
  Volume: 14 Pages: 1334335-1334335
- DOI
  10.3389/fpsyt.2023.1334335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors2023
- Author(s)
  Docherty Anna R.、Satoshi Okazaki（78／256番目）、他略
- Journal Title
  
  American Journal of Psychiatry
  
  Volume: 180 Issue: 10 Pages: 723-738
- DOI
  10.1176/appi.ajp.21121266
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Epigenetic clock analysis reveals increased plasma cystatin C levels based on DNA methylation in major depressive disorder.2023
- Author(s)
  Tanifuji T, Okazaki S, Otsuka I, Mouri K, Horai T, Shindo R, Shirai T, Hishimoto A.
- Journal Title
  
  Psychiatry Research
  
  Volume: Epub ahead of print Pages: 115103-115103
- DOI
  10.1016/j.psychres.2023.115103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans2023
- Author(s)
  Kimbrel Nathan A.、Hishimoto Akitoyo、Okazaki Satoshi、Otsuka Ikuo、et al.
- Journal Title
  
  JAMA Psychiatry
  
  Volume: 80 Issue: 2 Pages: 135-135
- DOI
  10.1001/jamapsychiatry.2022.3896
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] 精神疾患とエピゲノム、そしてエピゲノム年齢2023
- Author(s)
  白井寿行 , 岡崎賢志 , 谷藤貴紀 , 大塚郁夫 , 毛利健太朗 , 菱本明豊
- Journal Title
  
  仁明会精神医学研究
  
  Volume: 21 Pages: 51-71
- Data Source
  KAKENHI-PROJECT-21K07520
[Journal Article] Association of two variable number of tandem repeats in the monoamine oxidase A gene promoter with suicide completion: The present study and meta‐analysis2023
- Author(s)
  Hasegawa Masashi、Tanifuji Takaki、Okazaki Satoshi、Otsuka Ikuo、Shirai Toshiyuki、Shindo Ryota、Horai Tadasu、Mouri Kentaro、Takahashi Motonori、Kondo Takeshi、Ueno Yasuhiro、Hishimoto Akitoyo
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 43 Issue: 3 Pages: 338-345
- DOI
  10.1002/npr2.12344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K07545, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Telencephalon Organoids Derived from an Individual with ADHD Show Altered Neurodevelopment of Early Cortical Layer Structure2023
- Author(s)
  Zhang Danmeng、Eguchi Noriomi、Okazaki Satoshi、Sora Ichiro、Hishimoto Akitoyo
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: - Issue: 5 Pages: 1482-1491
- DOI
  10.1007/s12015-023-10519-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03584, KAKENHI-PROJECT-22K15750, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Ribosomal DNA gene copies are increased in blood and brain of Japanese schizophrenia patients2023
- Author(s)
  Li Sen、Otsuka Ikuo、Tanifuji Takaki、Okazaki Satoshi、Horai Tadasu、Takahashi Motonori、Kondo Takeshi、Ueno Yasuhiro、Hishimoto Akitoyo
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 1 Pages: e0280694-e0280694
- DOI
  10.1371/journal.pone.0280694
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder2023
- Author(s)
  Shindo Ryota、Tanifuji Takaki、Okazaki Satoshi、Otsuka Ikuo、Shirai Toshiyuki、Mouri Kentaro、Horai Tadasu、Hishimoto Akitoyo
- Journal Title
  
  npj Aging
  
  Volume: 9 Issue: 1 Pages: 19-19
- DOI
  10.1038/s41514-023-00117-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K07545, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852
[Journal Article] Accelerated epigenetic age and shortened telomere length based on DNA methylation in Nicolaides?Baraitser syndrome2022
- Author(s)
  Shinko Yutaka、Okazaki Satoshi、Otsuka Ikuo、Horai Tadasu、Kim Saehyeon、Tanifuji Takaki、Hishimoto Akitoyo
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 10 Issue: 3
- DOI
  10.1002/mgg3.1876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194
[Journal Article] Epigenetic aging in Williams syndrome2022
- Author(s)
  Okazaki Satoshi、Kimura Ryo、Otsuka Ikuo、Tomiwa Kiyotaka、Funabiki Yasuko、Hagiwara Masatoshi、Murai Toshiya、Hishimoto Akitoyo
- Journal Title
  
  Journal of Child Psychology and Psychiatry
  
  Volume: 63 Issue: 12 Pages: 1553-1562
- DOI
  10.1111/jcpp.13613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-19K08251, KAKENHI-PROJECT-21K15712, KAKENHI-PUBLICLY-21H05326, KAKENHI-PROJECT-23K22257
[Journal Article] Epigenetic clock analysis in methamphetamine dependence2022
- Author(s)
  Takemura Yukihiro、Tanifuji Takaki、Okazaki Satoshi、Shinko Yutaka、Otsuka Ikuo、Horai Tadasu、Shirai Toshiyuki、Aso Katsuro、Yamamoto Noriya、Hishimoto Akitoyo
- Journal Title
  
  Psychiatry Research
  
  Volume: 317 Pages: 114901-114901
- DOI
  10.1016/j.psychres.2022.114901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors2022
- Author(s)
  Mullins N, Ikuo Otsuka, Akitoyo Hishimoto et al.
- Journal Title
  
  Biological Psychiatry
  
  Volume: 91 Issue: 3 Pages: 313-327
- DOI
  10.1016/j.biopsych.2021.05.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712
[Journal Article] Polymorphisms in the hypoxia inducible factor binding site of the macrophage migration inhibitory factor gene promoter in schizophrenia2022
- Author(s)
  Okazaki Satoshi、Boku Shuken、Watanabe Yuichiro、Otsuka Ikuo、Horai Tadasu、Morikawa Ryo、Kimura Atsushi、Shimmyo Naofumi、Tanifuji Takaki、Someya Toshiyuki、Hishimoto Akitoyo
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 3 Pages: e0265738-e0265738
- DOI
  10.1371/journal.pone.0265738
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-20H03597
[Journal Article] Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis2022
- Author(s)
  Tanifuji Takaki、Otsuka Ikuo、Okazaki Satoshi、Horai Tadasu、So Ryuhei、Shiroiwa Kyoichi、Mouri Kentaro、Tanaka Motofumi、Ohmoto Nobuko、Sora Ichiro、Hirai Midori、Fukumoto Takumi、Ku Yonson、Hishimoto Akitoyo
- Journal Title
  
  Asian Journal of Psychiatry
  
  Volume: 78 Pages: 103282-103282
- DOI
  10.1016/j.ajp.2022.103282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K07545, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] Epigenetic clock analysis and increased plasminogen activator inhibitor-1 in high-functioning autism spectrum disorder2022
- Author(s)
  Okazaki Satoshi、Kimura Ryo、Otsuka Ikuo、Funabiki Yasuko、Murai Toshiya、Hishimoto Akitoyo
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 2 Pages: e0263478-e0263478
- DOI
  10.1371/journal.pone.0263478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-19K08251, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K18554, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21KK0041, KAKENHI-PUBLICLY-21H05326
[Journal Article] Clozapine increases macrophage migration inhibitory factor (MIF) expression via increasing histone acetylation of MIF promoter in astrocytes.2021
- Author(s)
  Okazaki S, Boku S, Otsuka I, Horai T, Kimura A, Shimmyo N, Yamaki N, Hishimoto A.
- Journal Title
  
  J Psychiatr Res.
  
  Volume: 135 Pages: 237-242
- DOI
  10.1016/j.jpsychires.2021.01.033
- NAID
  120006996932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-18K15483
[Journal Article] Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia2021
- Author(s)
  Tanifuji Takaki、Okazaki Satoshi、Otsuka Ikuo、Horai Tadasu、Shinko Yutaka、Kim Saehyeon、Sora Ichiro、Hishimoto Akitoyo
- Journal Title
  
  Neuropsychiatric Disease and Treatment
  
  Volume: Volume 17 Pages: 3315-3323
- DOI
  10.2147/ndt.s338854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194
[Journal Article] A preliminary genetic association study of GAD1 and GABAB receptor genes in patients with treatment-resistant schizophrenia2021
- Author(s)
  Miyazawa Atsuhiro、Kanahara Nobuhisa、Kogure Masanobu、Otsuka Ikuo、Okazaki Satoshi、Watanabe Yoshinori、Yamasaki Fumiaki、Nakata Yusuke、Oda Yasunori、Hishimoto Akitoyo、Iyo Masaomi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 3 Pages: 2015-2024
- DOI
  10.1007/s11033-021-07019-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07476, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-21K15724, KAKENHI-PROJECT-20KK0194
[Journal Article] Searching for biomarkers in schizophrenia and psychosis: Case‐control study using capillary electrophoresis and liquid chromatography time‐of‐flight mass spectrometry and systematic review for biofluid metabolites2021
- Author(s)
  Kim Saehyeon、Okazaki Satoshi、Otsuka Ikuo、Shinko Yutaka、Horai Tadasu、Shimmyo Naofumi、Hirata Takashi、Yamaki Naruhisa、Tanifuji Takaki、Boku Shuken、Sora Ichiro、Hishimoto Akitoyo
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 42 Issue: 1 Pages: 42-51
- DOI
  10.1002/npr2.12223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194
[Journal Article] Epigenetic Clock Analysis in Children With Fetal Alcohol Spectrum Disorder2021
- Author(s)
  Okazaki Satoshi、Otsuka Ikuo、Shinko Yutaka、Horai Tadasu、Hirata Takashi、Yamaki Naruhisa、Sora Ichiro、Hishimoto Akitoyo
- Journal Title
  
  Alcoholism: Clinical and Experimental Research
  
  Volume: 45 Issue: 2 Pages: 329-337
- DOI
  10.1111/acer.14532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-18K15483
[Journal Article] Decelerated Epigenetic Aging Associated With Mood Stabilizers in the Blood of Patients With Bipolar Disorder.2020
- Author(s)
  Okazaki S, Numata S, Otsuka I, Horai T, Kinoshita M, Sora I, Ohmori T, Hishimoto A.
- Journal Title
  
  Translational Psychiatry
  
  Volume: 10 Issue: 1 Pages: 129-129
- DOI
  10.1038/s41398-020-0813-y
- NAID
  120006850492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-18H02751, KAKENHI-PROJECT-18K15483
[Journal Article] miR-19b is elevated in peripheral blood of schizophrenic patients and attenuates proliferation of hippocampal neural progenitor cells2020
- Author(s)
  Horai T, Boku S, Okazaki S, Otsuka I, Ratta-Apha W, Mouri K, Yamaki N, Hirata T, Hishimoto A.
- Journal Title
  
  J Psychiatr Res .
  
  Volume: 131 Pages: 102-107
- DOI
  10.1016/j.jpsychires.2020.09.006
- NAID
  120006952760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484
[Journal Article] Chemokine Alterations in the Postmortem Brains of Suicide Completers2020
- Author(s)
  Shinko Y, Otsuka I, Okazaki S, Horai T, Boku S, Takahashi M, Ueno Y, Sora I, Hishimoto A.
- Journal Title
  
  J Psychiatr Res .
  
  Volume: 120 Pages: 29-33
- DOI
  10.1016/j.jpsychires.2019.10.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249
[Journal Article] ATP and Repetitive Electric Stimulation Increases Leukemia Inhibitory Factor Expression in Astrocytes: A Potential Role for Astrocytes in the Action Mechanism of Electroconvulsive Therapy2020
- Author(s)
  Maruyama S, Boku S, Okazaki S, Kikuyama H, Mizoguchi Y, Monji A, Otsuka I, Sora I, Kanazawa T, Hishimoto A, Yoneda H.
- Journal Title
  
  Psychiatry Clin Neurosci .
  
  Volume: . Issue: 5 Pages: 12986-12986
- DOI
  10.1111/pcn.12986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-17K10275
[Journal Article] Accelerated Extrinsic Epigenetic Aging and Increased Natural Killer Cells in Blood of Suicide Completers2020
- Author(s)
  Okazaki S, Otsuka I, Horai T, Hirata T, Takahashi M, Ueno Y, Boku S, Sora I, Hishimoto A.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry .
  
  Volume: 98 Pages: 109805-109805
- DOI
  10.1016/j.pnpbp.2019.109805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249
[Journal Article] Epigenetic clock analysis of blood samples from Japanese schizophrenia patients.2019
- Author(s)
  Okazaki S, Otsuka I, Numata S, Horai T, Mouri K, Boku S, Ohmori T, Sora I, Hishimoto A.
- Journal Title
  
  NPJ Schizophrenia
  
  Volume: 5 Issue: 1 Pages: 4-4
- DOI
  10.1038/s41537-019-0072-1
- NAID
  120006629323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-18H02751
[Journal Article] Mitochondrial DNA Copy Number Raises the Potential of Left Frontopolar Hemodynamic Response as a Diagnostic Marker for Distinguishing Bipolar Disorder From Major Depressive Disorder2019
- Author(s)
  Tsujii N, Otsuka I, Okazaki S, Yanagi M, Numata S, Yamaki N, Kawakubo Y, Shirakawa O, Hishimoto A.
- Journal Title
  
  Front Psychiatry
  
  Volume: 10 Pages: 312-312
- DOI
  10.3389/fpsyt.2019.00312
- NAID
  120006869526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15483
[Journal Article] Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population.2019
- Author(s)
  Otsuka I, Akiyama M, Shirakawa O, Okazaki S, Momozawa Y, Kamatani Y, Izumi T, Numata S, Takahashi M, Boku S, Sora I, Yamamoto K, Ueno Y, Toda T, Kubo M, Hishimoto A
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 44 Issue: 12 Pages: 2119-2124
- DOI
  10.1038/s41386-019-0506-5
- NAID
  120007027666
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08079, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-17H04249
[Journal Article] Major depressive disorder-associated SIRT1 locus affects the risk for suicide in women after middle age.2019
- Author(s)
  Hirata T, Otsuka I, Okazaki S, Mouri K, Horai T, Boku S, Takahashi M, Ueno Y, Sora I, Shirakawa O, Hishimoto A.
- Journal Title
  
  Psychiatry Res
  
  Volume: 278 Pages: 141-145
- DOI
  10.1016/j.psychres.2019.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249
[Journal Article] Investigation of chromosome Y loss in men with schizophrenia.2018
- Author(s)
  Hirata T, Hishimoto A, Otsuka I, Okazaki S, Boku S, Kimura A, Horai T, Sora I.
- Journal Title
  
  Neuropsychiatr Dis Treat.
  
  Volume: 14 Pages: 2115-2122
- DOI
  10.2147/ndt.s172886
- NAID
  120006510199
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276
[Journal Article] Mitochondrial DNA copy number of peripheral blood in bipolar disorder: The present study and a meta-analysis.2018
- Author(s)
  Yamaki N, Otsuka I, Numata S, Yanagi M, Mouri K, Okazaki S, Boku S, Horai T, Ohmori T, Shirakawa O, Sora I, Hishimoto A.
- Journal Title
  
  Psychiatry Research
  
  Volume: 269 Pages: 115-117
- DOI
  10.1016/j.psychres.2018.08.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765
[Journal Article] Loss of chromosome Y in blood, but not in brain, of suicide completers2018
- Author(s)
  Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 1 Pages: e0190667-e0190667
- DOI
  10.1371/journal.pone.0190667
- NAID
  120006382347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-16K10183, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276
[Journal Article] Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.2018
- Author(s)
  Okazaki S, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Boku S, Shimmyo N, Kinoshita M, Inoue E, Ohmori T, Someya T, Sora I.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry.
  
  Volume: 83 Pages: 33-41
- DOI
  10.1016/j.pnpbp.2018.01.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-17K16371, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276
[Journal Article] Aberrant telomere length and mitochondrial DNA copy number in suicide completers.2017
- Author(s)
  Otsuka I, Izumi T, Boku S, Kimura A, Zhang Y, Mouri K, Okazaki S, Shiroiwa K, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A
- Journal Title
  
  Scientific Report
  
  Volume: 7 Issue: 1 Pages: 3176-3176
- DOI
  10.1038/s41598-017-03599-8
- NAID
  120006373780
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10183, KAKENHI-PROJECT-16K19766, KAKENHI-PROJECT-15K19727
[Journal Article] Association study of MIF promoter polymorphisms with suicide completers in the Japanese population2017
- Author(s)
  Naofumi Shimmyo, Akitoyo Hishimoto, Ikuo Otsuka, Satoshi Okazaki, Shuken Boku, Kentaro Mouri, Tadasu Horai, Motonori Takahashi, Yasuhiro Ueno, Osamu Shirakawa, Ichiro Sora
- Journal Title
  
  Neuropsychiatric Disease and Treatment
  
  Volume: 13 Pages: 899-908
- DOI
  10.2147/ndt.s130855
- NAID
  120006024452
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461718, KAKENHI-PROJECT-15K19728, KAKENHI-PROJECT-15K19727
[Journal Article] The cell cycle-related genes as biomarkers for schizophrenia.2016
- Author(s)
  Okazaki S, Boku S, Otsuka I, Mouri K, Aoyama S, Shiroiwa K, Sora I, Fujita A, Shirai Y, Shirakawa O, Kokai M, Hishimoto A.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry
  
  Volume: 70 Pages: 85-91
- DOI
  10.1016/j.pnpbp.2016.05.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19728, KAKENHI-PROJECT-15K19727
[Journal Article] Rare truncating variations and risk of schizophrenia: Whole-exome sequencing in three families with affected siblings and a three-stage follow-up study in a Japanese population.2016
- Author(s)
  Watanabe Y, Nunokawa A, Shibuya M, Ikeda M, Hishimoto A, Kondo K, Egawa J, Kaneko N, Muratake T, Saito T, Okazaki S, Shimasaki A, Igeta H, Inoue E, Hoya S, Sugai T, Sora I, Iwata N, Someya T
- Journal Title
  
  Psychiatry Research
  
  Volume: 235 Pages: 13-18
- DOI
  10.1016/j.psychres.2015.12.011
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09802, KAKENHI-PROJECT-26461718, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-25461724
[Journal Article] A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia.2015
- Author(s)
  Ratta-Apha W, Mouri K, Boku S, Ishiguro H, Okazaki S, Otsuka I, Sora I, Arinami T, Shirakawa O, Hishimoto A.
- Journal Title
  
  Psychiatry Res.
  
  Volume: 230 Issue: 2 Pages: 424-429
- DOI
  10.1016/j.psychres.2015.09.031
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461718, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-15K19728
[Journal Article] Association analysis of the Cadherin13 gene with schizophrenia in the Japanese population.2015
- Author(s)
  Otsuka I, Watanabe Y, Hishimoto A, Boku S, Mouri K, Shiroiwa K, Okazaki S, Nunokawa A, Shirakawa O, Someya T, Sora I.
- Journal Title
  
  Neuropsychiatr Dis Treat.
  
  Volume: 11 Pages: 1381-1393
- DOI
  10.2147/ndt.s84736
- NAID
  120005657654
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461718, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-15K19728
[Journal Article] Association analysis of the HLA-DRB1*01 and HLA-DRB1*04 with schizophrenia by tag SNP genotyping in the Japanese population.2015
- Author(s)
  Ratta-apha W, Boku S, Mouri K, Okazaki S, Otsuka I, Watanabe Y, Nunokawa A, Someya T, Shirakawa O, Sora I, Hishimoto A.
- Journal Title
  
  Psychiatry Res.
  
  Volume: 229 Issue: 1-2 Pages: 627-628
- DOI
  10.1016/j.psychres.2015.07.016
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461718, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-15K19728
[Presentation] 自殺既遂者におけるMAOA遺伝子プロモーター領域のミニサテライト多型の関連解析とメタアナリシス2023
- Author(s)
  谷藤貴紀, 長谷川雅史, 岡崎賢志, 大塚郁夫,白井寿行, 新藤良太，蓬莱政, 毛利健太郎，高橋玄倫，近藤武史, 上野易弘，菱本明豊
- Organizer
  第45回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] うつ病患者におけるエピジェネティククロック解析とメチル化推定に基づくシスタチンCの増加2023
- Author(s)
  谷藤貴紀, 岡崎賢志, 大塚郁夫 , 毛利健太郎, 蓬莱政, 新藤良太, 白井寿行, 菱本明豊
- Organizer
  第23回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] ニコライデス・バライスター症候群におけるエピジェネティクス的年齢とテロメアの解析2022
- Author(s)
  谷藤貴紀, 新光穣, 岡崎賢志, 大塚郁夫, 蓬莱政,白井寿行,菱本明豊
- Organizer
  第44回日本生物学的精神医学会年会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] 精神病性障害に対するブレクスピプラゾールの使用経験2021
- Author(s)
  蓬莱政, 青山慎介, 木村敦, 新名尚史, 平田尚士, 岡崎賢志, 江口典臣, 山木愛久, 新光穣, 曽良一郎
- Organizer
  第117回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] Epigenetic clock analysis of blood samples from Japanese schizophrenia patients2021
- Author(s)
  Satoshi Okazaki, Ikuo Otsuka, Shusuke Numata, Tadasu Horai, Kentaro Mouri, Shuken Boku, Tetsuro Ohmori, Ichiro Sora, Akitoyo Hishimoto
- Organizer
  7th Congress of Asian College of Neuropsychopharmacology (AsCNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] Accelerated extrinsic epigenetic aging and increased natural killer cells in blood of suicide completers2021
- Author(s)
  S. Okazaki, I. Otsuka, T. Horai, T. Hirata, M. Takahashi, Y. Ueno, S. Boku, I. Sora, A. Hishimoto
- Organizer
  The International College of Neuropsychopharmacology (CINP) 2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] メタボローム解析による統合失調症血液バイオマーカーの探究2020
- Author(s)
  金世賢, 岡崎賢志, 大塚郁夫, 新光穣, 木村敦, 蓬莱政, 新名尚史, 平田尚士, 谷藤貴紀, 山木愛久, 青山慎介, 菱本明豊, 曽良一郎
- Organizer
  第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第9回日本精神薬学会総会・学術集会合同年会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] ADHD患者由来の大脳皮質オルガノイドで見られた大脳皮質発達の遅延(Telencephalon organoid derived from ADHD patient showed delayed development of cerebral cortex)2020
- Author(s)
  張丹夢, 江口典臣, 岡崎賢志, 曽良一郎
- Organizer
  第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第9回日本精神薬学会総会・学術集会合同年会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] 自殺完遂者の死後脳におけるケモカインの変化2020
- Author(s)
  新光穣, 大塚郁夫, 岡崎賢志, 蓬莱政, 朴秀賢, 高橋玄倫, 上野易弘, 曽良一郎, 菱本明豊
- Organizer
  第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第9回日本精神薬学会総会・学術集会合同年会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] 男性アルコール依存症患者の骨密度低下に関する横断的研究2019
- Author(s)
  蓬莱政, 菱本明豊, 大塚郁夫, 新名尚史, 岡崎賢志, 毛利健太朗, 朴秀賢, 曽良一郎
- Organizer
  日本精神神経学会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] Mir-19b is increased in peripheral blood of schizophenic patients and a!ects proliferation and survival of hippocampal neural progenitor cells2019
- Author(s)
  Boku S, Horai T, Okazaki S, Otsuka I, Mouri K, Hishimoto A
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] 統合失調症におけるマクロファージ遊走阻止因子(MIF)の血清濃度増加と遺伝子多型関連解析2019
- Author(s)
  岡崎賢志, 大塚郁夫, 渡部雄一郎, 朴秀賢, 新名尚史, 平田尚士, 蓬莱政, 染矢俊幸, 曽良一郎, 菱本明豊
- Organizer
  日本精神神経学会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] 自殺既遂者の血液・脳組織におけるY染色体喪失の解析2019
- Author(s)
  木村敦, 菱本明豊, 平田尚士, 山本愛久, 蓬莱政, 新名尚史, 大塚郁夫, 岡崎賢志, 朴秀賢, 曽良一郎
- Organizer
  日本精神神経学会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] 統合失調症におけるY染色体モザイク欠損の検討2019
- Author(s)
  平田尚士, 菱本明豊, 大塚郁夫, 岡崎賢志, 朴秀賢, 木村敦, 蓬莱政, 曽良一郎
- Organizer
  日本精神神経学会
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] The cell cycle-related genes as biomarkers for schizophrenia2018
- Author(s)
  Okazaki S, Boku S, Otsuka I, Eguchi N, Sora I, Hishimoto A
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia2018
- Author(s)
  Okazaki S, Otsuka I, Wanatabe Y, Numata S, Boku S, Shimmyo N, Ormori T, Someya T, Sora I, Hishimoto A
- Organizer
  WFSBP Asia Pacific Regional Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] Loss of chromosome Y in blood, but not in brain, of suicide completers2018
- Author(s)
  Otsuka I, Okazaki S, Kimura A, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A
- Organizer
  WFSBP Asia Pacific Regional Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] Mosaic loss of chromosome Y in peripheral blood and its risk variants in men with schizophrenia2018
- Author(s)
  Hirata T, Okazaki S, Otsuka I, Boku S, Aoyama S, Eguch N, Kimura A, Horai T, Sora I, Hishimoto A
- Organizer
  WFSBP Asia Pacific Regional Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] Mechanism of modified electroconvulsive therapy - electrical stimulation to neurogenesis2018
- Author(s)
  Maruyama S, Boku S, Okazaki S, Kikuyama H, Kanazawa T, Yoneda H
- Organizer
  World Psychiatric Association’s Thematic Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19727
[Presentation] Mechanism of modified electroconvulsive therapy - electrical stimulation to neurogenesis2018
- Author(s)
  Maruyama S, Boku S, Okazaki S, Kikuyama H, Kanazawa T, Yoneda H
- Organizer
  WFSBP Asia Pacific Regional Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483
[Presentation] 日本人自殺既遂者におけるMIF遺伝子プロモーター領域機能多型の関連解析2017
- Author(s)
  新名尚史、菱本明豊、大塚郁夫、岡崎賢志、朴秀賢、毛利健太朗、蓬莱政、江口典臣、木村敦、山木愛久、平田尚士、高橋玄倫、上野易弘、白川治、曽良一郎
- Organizer
  日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-15K19727
[Presentation] 自殺既遂者におけるテロメア異常短縮2017
- Author(s)
  大塚郁夫、菱本明豊、泉剛、朴秀賢、木村敦、張園、毛利健太朗、岡崎賢志、高橋玄倫、上野易弘、白川治、曽良一郎
- Organizer
  日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-15K19727

1. 蓬莱政 (90817826)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. 江口典臣 (80814566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 大塚郁夫 (40722880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
4. HISHIMOTO Akitoyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 20 results
5. BOKU Syuken

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. IZUMI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. NUNOKAWA Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. KANARAHA Nobuhisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 曽良一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
10. 毛利健太朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 渡辺雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 白河治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 仲田祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 高橋健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKAZAKI SATOSHI 岡崎 賢志

OKAZAKI Satoshi 岡崎 賢志

Research Projects

Research Products

Co-Researchers

Epigenetic pathomechanisms of accelerated aging in schizophreniaPrincipal Investigator

Principal Investigator

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Research Institution

Molecular mechanisms linking hypoxia exposure and schizophrenia with a focus on MIF.Principal Investigator

Principal Investigator

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Review Section

Research Institution

Molecular pathology of schizophrenia and novel mechanisms of antipsychotics from the perspective of MIFPrincipal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

The role of macrophage migration inhibitory factor (MIF) in the neuroimmunological hypothesis of schizophreniaPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Association study of a single nucleotide polymorphism in the hypoxia response element of the macrophage migration inhibitory factor gene promoter with suicide completers in the Japanese population2024

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[Journal Article] Epigenome‐wide association study on methamphetamine dependence2024

Author(s)

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[Journal Article] Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia2024

Author(s)

Journal Title

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Data Source

[Journal Article] GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors2023

Author(s)

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Data Source

[Journal Article] Epigenetic clock analysis reveals increased plasma cystatin C levels based on DNA methylation in major depressive disorder.2023

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[Journal Article] Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans2023

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[Journal Article] 精神疾患とエピゲノム、そしてエピゲノム年齢2023

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[Journal Article] Association of two variable number of tandem repeats in the monoamine oxidase A gene promoter with suicide completion: The present study and meta‐analysis2023

Author(s)

Journal Title

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Data Source

[Journal Article] Telencephalon Organoids Derived from an Individual with ADHD Show Altered Neurodevelopment of Early Cortical Layer Structure2023

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Journal Title

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Data Source

[Journal Article] Ribosomal DNA gene copies are increased in blood and brain of Japanese schizophrenia patients2023

Author(s)

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Data Source

[Journal Article] Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder2023

Author(s)

OKAZAKI SATOSHI 岡崎賢志

OKAZAKI Satoshi 岡崎賢志