Arima Yasunobu 有馬康伸

Researcher Number	70724748
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2017: 北海道大学, 遺伝子病制御研究所, 助教
Review Section/Research Field	Principal Investigator Immunology
Keywords	Principal Investigator 神経活性化 / 炎症 / ゲートウェイ反射 / 脳神経疾患 / 活性化モノサイト / 多発性硬化症 / 疼痛ストレス / ストレス

中枢炎症の再発に重要な長期生存型活性化モノサイトの生存因子の同定と分子機構解析Principal Investigator
- Principal Investigator
  
  有馬康伸
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Investigation of inflammation mechanisms via the stress-mediated endothelial cell activationPrincipal Investigator
- Principal Investigator
  
  Arima Yasunobu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University

All 2017 2016 2015

All Journal Article Presentation Book

[Book] Multiple Sclerosis2015
- Author(s)
  Kamimura, D., Y. Arima, T. Atsumi, J. Meng, L. Sabharwal, H. Bando, J-J. Jiang, ES. Huseby, M. Murakami.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-15K19122
[Journal Article] Gateway reflexes are stimulated by neural activations and promote the pathogenesis of multiple sclerosis models.2017
- Author(s)
  Higuchi, K., D. Kamimura, A. Stofkova, N. Nishikawa, T. Ohki, Y. Arima, M. Murakami.
- Journal Title
  
  Nutrition and Lifestyle in Neurological Autoimmune Diseases
  
  Volume: Chapter 5 Pages: 39-45
- DOI
  10.1016/b978-0-12-805298-3.00005-0
- ISBN
  9780128052983
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19122
[Journal Article] Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit.2017
- Author(s)
  Arima, Y., T. Ohki, N. Nishikawa, K. Higuchi, M. Ota, Y. Tanaka, J. Nio-Kobayashi, M. Elfeky, R. Sakai, Y. Mori, T. Kawamoto, A. Stofkova, Y. Sakashita, Y. Morimoto, M. Kuwatani, T. Iwanaga, Y. Yoshioka, N. Sakamoto, A. Yoshimura, M. Takiguchi, S. Sakoda, M. Prinz, D. Kamimura, M. Murakami.
- Journal Title
  
  eLife
  
  Volume: 6:e25517 Pages: 1-27
- DOI
  10.7554/elife.25517
- NAID
  120006360081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19537, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-15K08518, KAKENHI-PROJECT-17K15712
[Journal Article] Recent advances in neuroimmune interactions.2017
- Author(s)
  Murakami, M.
- Journal Title
  
  Clin Exp Neuroimmunol.
  
  Volume: 8 Issue: 1 Pages: 3-4
- DOI
  10.1111/cen3.12382
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-17K19537, KAKENHI-PROJECT-15H04741
[Journal Article] The gateway reflex, a novel neuro-immune interaction for the regulation of regional vessels.2017
- Author(s)
  Tanaka, Y., Y. Arima, D. Kamimura, and M. Murakami.
- Journal Title
  
  Front Immunol.
  
  Volume: 8 Pages: 1-9
- DOI
  10.3389/fimmu.2017.01321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19537, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-15K08518, KAKENHI-PROJECT-17K15712
[Journal Article] EAE Induction by Passive Transfer of MOG-specific CD4+ T Cells.2017
- Author(s)
  Tanaka, Y., Y. Arima, K. Higuchi, T. Ohki, M. Elfeky, M. Ota, D. Kamimura and M. Murakami.
- Journal Title
  
  Bio-protocol.
  
  Volume: 7(13) Issue: 13 Pages: 1-13
- DOI
  10.21769/bioprotoc.2370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19537, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-17K15712
[Journal Article] Breakpoint cluster region-mediated inflammation is dependent on casein kinase II.2016
- Author(s)
  Meng, J., J-J Jiang, T. Atsumi, H. Bando, Y. Okuyama, L. Sabharwal, I. Nakagawa, H. Higuchi, M. Ota, M. Okawara, R. Ishitani, O. Nureki, D. Higo, Y. Arima, H. Ogura, D. Kamimura and M. Murakami.
- Journal Title
  
  J Immunol.
  
  Volume: 197(8) Issue: 8 Pages: 3111-3119
- DOI
  10.4049/jimmunol.1601082
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26460574, KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122
[Journal Article] Control of chronic inflammation by the inflammation amplifier and gateway reflexes.2016
- Author(s)
  Ota, M., D. Kamimura, I. Nakagawa, H. Higuchi, Y. Tanaka, M. Fujita, S. Hiratsuka, M. Okawara, K. Murakami, T. Atsumi, Y. Arima and M. Murakami.
- Journal Title
  
  Advances in Medicine and Biology
  
  Volume: 104: Chapter 4 Pages: 65-86
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19122
[Journal Article] Strong TCR-mediated signals suppress integrated stress responses induced by KDELR1 deficiency in naive T cells.2016
- Author(s)
  Kamimura, D. Y. Arima, M. Tsuruoka, J-J Jiang, H. Bando, J. Meng, L. Sabharwal, A. Stofkova, N. Nishikawa, K. Higuchi, H. Ogura, T. Atsumi, M. Murakami.
- Journal Title
  
  Int Immunol.
  
  Volume: 28(3) Issue: 3 Pages: 117-126
- DOI
  10.1093/intimm/dxv059
- NAID
  120005851045
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-14F04789, KAKENHI-PROJECT-26460574, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-15K08518
[Journal Article] Role of inflammation amplifier-induced growth factor expression in the development of inflammatory diseases.2015
- Author(s)
  Nakagawa, I., D. Kamimura, T. Atsumi, Y. Arima, M. Murakami.
- Journal Title
  
  Crit Rev Immunol.
  
  Volume: 35(5) Pages: 365-78
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19122
[Journal Article] A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model2015
- Author(s)
  Arima, Y., D. Kamimura, T. Atsumi, M. Harada, T. Kawamoto, N. Nishikawa, A. Stofkova1, T. Ohki, K. Higuchi, Y. Morimoto, P. Wieghofer, Y. Okada, Y. Mori, S. Sakoda, S. Saika, Y. Yoshioka, I. Komuro, T. Yamashita, T. Hirano, M. Prinz, M. Murakami.
- Journal Title
  
  eLife
  
  Volume: 4 Pages: 1-23
- DOI
  10.7554/elife.08733
- NAID
  120005757989
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-14F04789, KAKENHI-PROJECT-26860996
[Journal Article] Immune Cell Gateways in the CNS Regulated by Regional Neural Stimulations.2015
- Author(s)
  Kamimura, D., A. Stofkova, N. Nishikawa, T. Atsumi, Y. Arima, M. Murakami.
- Journal Title
  
  Clin Exp Neuroimmunol.
  
  Volume: 印刷中 Issue: 2 Pages: 120-128
- DOI
  10.1111/cen3.12198
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659221, KAKENHI-PROJECT-26460574, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-14F04789
[Journal Article] KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.2015
- Author(s)
  Kamimura, D., K. Katsunuma, Y. Arima, T. Atsumi, J-J Jiang, H. Bando, J. Meng, L. Sabharwal, A. Stofkova, N. Nishikawa, H. Suzuki, H. Ogura, N. Ueda, M. Tsuruoka, M. Harada, J. Kobayashi, T. Hasegawa, H. Yoshida, H. Koseki, I. Miura, S. Wakana, K. Nishida, H. Kitamura, T. Fukada, T. Hirano, and M. Murakami
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 7474-7474
- DOI
  10.1038/ncomms8474
- NAID
  120005647268
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08518, KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-14F04789
[Journal Article] Role of T cell- glial cell interactions in creating and amplifying Central Nervous System inflammation and Multiple Sclerosis disease symptoms.2015
- Author(s)
  Huseby, ES., D. Kamimura, Y. Arima, CS. Parello, K. Sasaki, M. Murakami.
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 9
- DOI
  10.3389/fncel.2015.00295
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08518, KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-15H04741
[Journal Article] Pain is an inducer for relapse in multiple sclerosis models via a regional neural signal.2015
- Author(s)
  Arima, Y., K. Higuchi, N. Nishikawa, A. Stofkova, T Ohki, D. Kamimura, M. Murakami.
- Journal Title
  
  Clin Exp Neuroimmunol.
  
  Volume: 6 Issue: 4 Pages: 343-344
- DOI
  10.1111/cen3.12250
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-14F04789
[Journal Article] Naive T cell homeostasis regulated by stress responses and TCR signaling.2015
- Author(s)
  Kamimura, D., T. Atsumi, A. Stofkova, N. Nishikawa, T. Ohki, H. Suzuki, K. Katsunuma, J-J Jiang, H. Bando, J. Meng, L. Sabharwal, H. Ogura, T. Hirano, Y. Arima, M. Murakami.
- Journal Title
  
  Front Immunol
  
  Volume: 6
- DOI
  10.3389/fimmu.2015.00638
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08518, KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-14F04789
[Presentation] Stress-Gateway Reflex, which establishes brain micro-inflammation at specific vessels, creates a new neural pathway, which induces the dysregulation of organ homeostasis2017
- Author(s)
  Yasunobu Arima
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15712
[Presentation] Stress-Gateway Reflex, how stress induces gastrointestinal diseases with high mortality2017
- Author(s)
  Yasunobu Arima
- Organizer
  第12回研究所ネットワーク国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15712
[Presentation] Brain micro-inflammation at specific vessels establishes a new neural circuit, which dysregulates the gastrointestinal homeostasis under stress conditions2017
- Author(s)
  Yasunobu Arima
- Organizer
  第5回国際インターフェロンサイトカイン学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15712
[Presentation] A Pain-mediated Neural Signal Induces Relapse in An Experimental Autoimmune Encephalomyelitis.2016
- Author(s)
  Yasunobu Arima
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄県
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 痛み刺激による感覚-交感神経活性化を介した多発性硬化症モデルEAEの再発機構の解析2016
- Author(s)
  有馬康伸
- Organizer
  第49回北海道病理談話会
- Place of Presentation
  北海道大学医学部学友会館フラテ、札幌市、北海道
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] Pain is an inducer for relapse in multiple sclerosis models via the sensory-sympathetic nerve activation2016
- Author(s)
  Yasunobu Arima
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  Merborne, Australia
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] Pain is an inducer for relapse in multiple sclerosis models via the sensory-sympathetic nerve activation.2016
- Author(s)
  有馬康伸
- Organizer
  Stromal Cells in Immunity
- Place of Presentation
  keystone (Colorado, US)
- Year and Date
  2016-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 痛み刺激は感覚神経-交感神経の活性化を介して多発性硬化症モデルの病態を再発させる2016
- Author(s)
  有馬康伸
- Organizer
  第89回日本生化学大会
- Place of Presentation
  東北大学、仙台市、宮城県
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 痛み刺激による感覚-交感神経活性化を介した多発性硬化症モデルEAEの再発機構の解析2016
- Author(s)
  有馬康伸
- Organizer
  第28回日本神経免疫学会学術集会
- Place of Presentation
  長崎ブリックホール、長崎市、長崎県
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 痛み刺激は感覚-交感神経活性化を介して多発性硬化症モデルEAEの再発を誘導する2016
- Author(s)
  有馬康伸
- Organizer
  第81回日本インターフェロンサイトカイン学会学術集会
- Place of Presentation
  長崎大学、長崎市、長崎県
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 痛み刺激による感覚-交感神経活性化を介した多発性硬化症モデルEAEの再発機構の解明2016
- Author(s)
  有馬康伸
- Organizer
  第53回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学鈴木章ホール、札幌市、北海道
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 神経刺激による炎症制御機構の解明2015
- Author(s)
  有馬康伸
- Organizer
  第2回JCRベーシックリサーチカンファレンス
- Place of Presentation
  東京大学 (東京都、文京区)
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] Regional Neural Activation Influences Immune Signals in The Central Nervous System via The Inflammation Amplifier Activation2015
- Author(s)
  有馬康伸
- Organizer
  UCL Molecular Cell Biology Symposium 2015
- Place of Presentation
  Senate House (London, UK)
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] A Cellular Metabolite in An Inflammation Site Regulates The Pathological Condition of Experimental Autoimmune Encephalomyelitis.2015
- Author(s)
  有馬康伸
- Organizer
  日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター (北海道、札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19122
[Presentation] 痛み刺激は感覚-交感神経活性化を介して多発性硬化症モデルEAEの再発を誘導する2015
- Author(s)
  有馬康伸
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド (兵庫県、神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19122

1. Kamimura Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
2. 村上正晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results

Arima Yasunobu 有馬 康伸

Research Projects

Research Products

Co-Researchers

中枢炎症の再発に重要な長期生存型活性化モノサイトの生存因子の同定と分子機構解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of inflammation mechanisms via the stress-mediated endothelial cell activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Multiple Sclerosis2015

Author(s)

Publisher

Data Source

[Journal Article] Gateway reflexes are stimulated by neural activations and promote the pathogenesis of multiple sclerosis models.2017

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Recent advances in neuroimmune interactions.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The gateway reflex, a novel neuro-immune interaction for the regulation of regional vessels.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EAE Induction by Passive Transfer of MOG-specific CD4+ T Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Breakpoint cluster region-mediated inflammation is dependent on casein kinase II.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of chronic inflammation by the inflammation amplifier and gateway reflexes.2016

Author(s)

Journal Title

Data Source

[Journal Article] Strong TCR-mediated signals suppress integrated stress responses induced by KDELR1 deficiency in naive T cells.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Role of inflammation amplifier-induced growth factor expression in the development of inflammatory diseases.2015

Author(s)

Journal Title

Data Source

[Journal Article] A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Immune Cell Gateways in the CNS Regulated by Regional Neural Stimulations.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.2015

Author(s)

Journal Title

Arima Yasunobu 有馬康伸

[Presentation] 痛み刺激は感覚神経-交感神経の活性化を介して多発性硬化症モデルの病態を再発させる2016

[Presentation] 痛み刺激による感覚-交感神経活性化を介した多発性硬化症モデルEAEの再発機構の解析2016