Miyabe Megumi 宮部愛

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MIYABE Megumi 宮部愛

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Researcher Number	70734929
Other IDs
Affiliation (Current)	2025: 愛知学院大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 愛知学院大学, 歯学部, 講師 2014 – 2018: 愛知学院大学, 歯学部, 講師
Review Section/Research Field	Principal Investigator Periodontology / Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 歯周病 / 動脈硬化 / 炎症 / 歯周炎 / 慢性炎症 / マイオカイン / 診断学 / 歯周病態 / 血管リモデリング

The effect of myokines on the progression of arteriosclerosis associated with periodontal diseasePrincipal Investigator
- Principal Investigator
  
  Miyabe Megumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Aichi Gakuin University
Study on the progress of periodontal disease and arteriosclerosisPrincipal Investigator
- Principal Investigator
  
  Miyabe Megumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Aichi Gakuin University
The investigation of the effects of periodontitis on aterosclerosisPrincipal Investigator
- Principal Investigator
  
  MIYABE Megumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontology
- Research Institution
  Aichi Gakuin University

All 2023 2022 2021 2018 2017 2016 2014

All Journal Article Presentation

[Journal Article] Salivary gland polymorphous adenocarcinoma: Clinicopathological features and gene alterations in 36 Japanese patients2022
- Author(s)
  Fukumura Masahiro、Ishibashi Kenichiro、Nakaguro Masato、Kirita Tadaaki、Takata Takashi、Morinaga Shojiroh、Maeda Hatsuhiko、Warnakulasuriya Saman、Miyabe Satoru、Nagao Toru, et al.
- Journal Title
  
  Journal of Oral Pathology & Medicine
  
  Volume: 51 Issue: 8 Pages: 710-720
- DOI
  10.1111/jop.13336
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10272, KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-22K09938, KAKENHI-PROJECT-21K16981, KAKENHI-PROJECT-19K10081, KAKENHI-PROJECT-20K07417, KAKENHI-PROJECT-20K10149, KAKENHI-PROJECT-17K18213, KAKENHI-PROJECT-23K24116
[Journal Article] Impacts of Glucose-Dependent Insulinotropic Polypeptide on Orthodontic Tooth Movement-Induced Bone Remodeling2022
- Author(s)
  Yamauchi Taisuke、Miyabe Megumi、Nakamura Nobuhisa、Ito Mizuho、Sekiya Takeo、Kanada Saki、Hoshino Rina、Matsubara Tatsuaki、Miyazawa Ken、Goto Shigemi、Naruse Keiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 16 Pages: 8922-8922
- DOI
  10.3390/ijms23168922
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08948, KAKENHI-PROJECT-22K09974, KAKENHI-PROJECT-21K16981
[Journal Article] Increased expression of angiopoietin‐like protein 4 regulates matrix metalloproteinase‐13 expression in <i>Porphyromonas gingivalis</i> lipopolysaccharides‐stimulated gingival fibroblasts and ligature‐induced experimental periodontitis2022
- Author(s)
  Kondo Shun、Kojima Kento、Nakamura Nobuhisa、Miyabe Megumi、Kikuchi Takeshi、Ohno Tasuku、Sawada Noritaka、Minato Tomomi、Saiki Tomokazu、Ito Mizuho、Sasajima Sachiko、Matsubara Tatsuaki、Mitani Akio、Naruse Keiko
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 58 Issue: 1 Pages: 43-52
- DOI
  10.1111/jre.13067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10138, KAKENHI-PROJECT-20K09985, KAKENHI-PROJECT-22K08948, KAKENHI-PROJECT-22K09974, KAKENHI-PROJECT-21K16981, KAKENHI-PROJECT-23K09177
[Journal Article] Porphyromonas gingivalis Lipopolysaccharides Promote Proliferation and Migration of Human Vascular Smooth Muscle Cells through the MAPK/TLR4 Pathway2022
- Author(s)
  Miyabe Megumi、Nakamura Nobuhisa、Saiki Tomokazu、Miyabe Satoru、Ito Mizuho、Sasajima Sachiko、Minato Tomomi、Matsubara Tatsuaki、Naruse Keiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 1 Pages: 125-125
- DOI
  10.3390/ijms24010125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08948, KAKENHI-PROJECT-22K09974, KAKENHI-PROJECT-21K16981
[Journal Article] The Effects of Insulin on Immortalized Rat Schwann Cells, IFRS12021
- Author(s)
  Tomokazu Saiki, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Tomomi Minato, Kazunori Sango, Tatsuaki Matsubara, Keiko Naruse
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 11 Pages: 5505-5505
- DOI
  10.3390/ijms22115505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-21K16981
[Journal Article] β-Aminoisobutyric acid, L-BAIBA, protects PC12 cells from hydrogen peroxide-induced oxidative stress and apoptosis via activation of the AMPK and PI3K/Akt pathway2021
- Author(s)
  Tomomi Minato, Nobuhisa Nakamura, Tomokazu Saiki, Megumi Miyabe, Mizuho Ito, Tatsuaki Matsubara, Keiko Naruse
- Journal Title
  
  IBRO Neurosci Rep
  
  Volume: 12 Pages: 65-72
- DOI
  10.1016/j.ibneur.2021.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-21K16981
[Journal Article] Case Report: Non-episodic Angioedema With Eosinophilia in a Young Lactating Woman.2021
- Author(s)
  Mizuho Hirmatsu-Ito, Nobuhisa Nakamura, Megumi Miyabe, Tatsuaki Matsubar, Keiko Naruse
- Journal Title
  
  Front Immunol
  
  Volume: 12 Pages: 627360-627360
- DOI
  10.3389/fimmu.2021.627360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-21K16981
[Journal Article] Sustainable Effects of Human Dental Pulp Stem Cell Transplantation on Diabetic Polyneuropathy in Streptozotocine-Induced Type 1 Diabetes Model Mice.2021
- Author(s)
  Masaki Hata, Maiko Omi, Yasuko Kobayashi, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Tasuku Ohno, Yuka Imanishi, Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura, Hitoshi Miyachi, Shogo Ozawa, Ken Miyazawa, Akio Mitani, Toru Nagao, Shigemi Goto, Jun Takebe, Tatsuaki Matsubara, Keiko Naruse
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 9 Pages: 2473-2473
- DOI
  10.3390/cells10092473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-19K10138, KAKENHI-PROJECT-20K10082, KAKENHI-PROJECT-21K16981
[Journal Article] Chemerin promotes angiogenesis in vivo.2018
- Author(s)
  Nakamura N, Naruse K, Kobayashi Y, Miyabe M, Saiki T, Enomoto A, Takahashi M, Matsubara T.
- Journal Title
  
  Physiological Reports
  
  Volume: 6 Issue: 24 Pages: e13962-e13962
- DOI
  10.14814/phy2.13962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11846, KAKENHI-PROJECT-16K20682
[Journal Article] Transplantation of dental pulp stem cells improves long-term diabetic polyneuropathy together with improvement of nerve morphometrical evaluation.2017
- Author(s)
  3.Omi M, Hata M, Nakamura N, Miyabe M, Ozawa S, Nukada H, Tsukamoto M, Sango K, Himeno T, Kamiya H, Nakamura J, Takebe J, Matsubara T, Naruse K.
- Journal Title
  
  Stem Cell Research and Therapy
  
  Volume: 8 Issue: 1 Pages: 279-279
- DOI
  10.1186/s13287-017-0729-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07048, KAKENHI-PROJECT-16K11616, KAKENHI-PROJECT-16K11846, KAKENHI-PROJECT-16K20682, KAKENHI-PROJECT-15K11181
[Journal Article] Role of poly(ADP-ribose) polymerase activation in the pathogenesis of periodontitis in diabetes.2017
- Author(s)
  Adachi K, Miyajima SI, Nakamura N, Miyabe M, Kobayashi Y, Nishikawa T, Suzuki Y, Kikuchi T, Kobayashi S, Saiki T, Mizutani M, Ohno N, Noguchi T, Mitani A, Matsubara T, Naruse K.
- Journal Title
  
  J Clin Periodontol
  
  Volume: 44(10) Issue: 10 Pages: 971-980
- DOI
  10.1111/jcpe.12758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11845, KAKENHI-PROJECT-16K11846, KAKENHI-PROJECT-17K11999, KAKENHI-PROJECT-16K20682, KAKENHI-PROJECT-26463149
[Journal Article] Muscle-derived follistatin-like 1 function to reduce neointimal formation after vascular injury.2014
- Author(s)
  Megumi Miyabe
- Journal Title
  
  Cardiovasc Res
  
  Volume: 103 Issue: 1 Pages: 111-120
- DOI
  10.1093/cvr/cvu105
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26893303
[Presentation] The involvement of ANGPTL4 in periodontitis and the influence of high glucose.2023
- Author(s)
  Kondo S, Kojima K, Nakamura N, Miyabe M, Kikuchi T, Ohno T, Sawada N, Minato T, Saiki T, Ito M, Sasajima S, Matsubara T, Mitani A, Naruse K
- Organizer
  American Diabetes Association’s 83rd Scientific Sessions
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] Impacts of Glucose-Dependent Insulinotropic Polypeptide on Bone Remodeling.2023
- Author(s)
  Yamauchi T, Nakamura N, Miyabe M, Ito M, Hosino R, Kanada S, Miyazawa K, Goto S, Naruse K
- Organizer
  IDF-WPR Congress 2023 / 15thAASD Scientific Meeting in Conjunction with JADEC Annual Scientific Meeting
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] メタボリックシンドローム合併歯周炎に対するGLP-1受容体作動薬の効果-Zucker fattyラットを用いた検討-．2023
- Author(s)
  近藤　駿、澤田憲孝、小島健人、笹島沙知子、湊　智美、中村信久、菊池　毅、鈴木佑基、宮部　愛、伊藤瑞穂、三谷章雄、成瀬桂子
- Organizer
  第36回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] マイオカインによる歯周炎が関与する動脈硬化の進展抑制に対する効果と歯周組織の再生における効果の検討．2023
- Author(s)
  宮部　愛、中村信久、伊藤瑞穂、笹島佐知子、成瀬桂子
- Organizer
  愛知学院大学歯学会第102回学術大会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] DPNcheckで測定した腓腹神経伝導速度の有用性の検討2023
- Author(s)
  伊藤瑞穂、中村信久、小林泰子、宮部愛、笹島沙知子、成瀬桂子
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] Transplantation of dental pulp stem cells ameliorates hindlimb skeletal muscle atrophy and peripheral nerve dysfunction in diabetic rats2023
- Author(s)
  Naruse K, Omi M, Hata M, Nakamura N, Miyabe M, Sasajima S, Ozawa S, Takebe J, Matsubara T.
- Organizer
  33rd Annual Meeting of the Diabetic Neuropathy Study Group
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] 歯周炎におけるANGPTL4の関与と高グルコースの影響2023
- Author(s)
  近藤駿、小島健人、中村信久、宮部愛、菊池毅、大野　祐、澤田憲孝、湊　智美、斉木智一、伊藤瑞穂、笹島沙知子、松原達昭、三谷章雄、成瀬桂子
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] Extrapancreatic effects of GIP on bone.2023
- Author(s)
  Yamauchi T, Nakamura N, Miyabe M, Ito M, Hosino R, Kanada S, Sekiya T, Miyazawa K, Goto S, Naruse K
- Organizer
  American Diabetes Association’s 83rd Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] マイオカインによる歯周炎が関与する動脈硬化の進展抑制に対する効果と再生医療への展望2022
- Author(s)
  宮部愛、中村信久、伊藤瑞穂、斎木智一、松原達昭、成瀬桂子
- Organizer
  第100回愛知学院大学歯学会総会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] 歯周病の存在が動脈硬化促進に影響を及ぼす可能性についての検討2022
- Author(s)
  宮部愛、中村信久、伊藤瑞穂、斎木智一、松原達昭、成瀬桂子
- Organizer
  第54回動脈硬化学会総会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] 歯周病原細菌由来LPSは血管平滑筋細胞の増殖・遊走を促進する2021
- Author(s)
  宮部　愛、中村　信久、伊藤　瑞穂、斎木　智一、松原　達昭、成瀬　桂子
- Organizer
  第36回糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] 歯周病が動脈硬化の促進に及ぼす可能性についての検討2021
- Author(s)
  宮部　愛、中村　信久、伊藤　瑞穂、斎木　智一、松原　達昭、成瀬　桂子
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-21K16981
[Presentation] Chemerinの血管形成作用とChemerin受容体の同定2018
- Author(s)
  中村信久、成瀬桂子、宮部愛、伊藤瑞穂、松原達昭
- Organizer
  第50回日本動脈硬化学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20682
[Presentation] GIPによる歯周炎抑制作用についての検討2016
- Author(s)
  鈴木佑基，宮部愛 (他　16名、4番目）
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  みやこめっせ（京都府京都市左京区）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K20682
[Presentation] GIPによる歯周炎抑制経路の検討2016
- Author(s)
  鈴木佑基, 宮部愛 (他　6名、3番目）
- Organizer
  第11回日本歯周病学会中部地区大学・日本臨床歯周病学会中部支部合同研究会
- Place of Presentation
  朝日大学(岐阜県瑞穂市穂積）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-16K20682

1. 成瀬桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
2. 桐田忠昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 森英一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 中村信久

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 伊藤瑞穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 三谷章雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 菊池毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 三五一憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyabe Megumi 宮部 愛

MIYABE Megumi 宮部 愛

Research Projects

Research Products

Co-Researchers

The effect of myokines on the progression of arteriosclerosis associated with periodontal diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the progress of periodontal disease and arteriosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation of the effects of periodontitis on aterosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Salivary gland polymorphous adenocarcinoma: Clinicopathological features and gene alterations in 36 Japanese patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impacts of Glucose-Dependent Insulinotropic Polypeptide on Orthodontic Tooth Movement-Induced Bone Remodeling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased expression of angiopoietin‐like protein 4 regulates matrix metalloproteinase‐13 expression in <i>Porphyromonas gingivalis</i> lipopolysaccharides‐stimulated gingival fibroblasts and ligature‐induced experimental periodontitis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Porphyromonas gingivalis Lipopolysaccharides Promote Proliferation and Migration of Human Vascular Smooth Muscle Cells through the MAPK/TLR4 Pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Effects of Insulin on Immortalized Rat Schwann Cells, IFRS12021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] β-Aminoisobutyric acid, L-BAIBA, protects PC12 cells from hydrogen peroxide-induced oxidative stress and apoptosis via activation of the AMPK and PI3K/Akt pathway2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Case Report: Non-episodic Angioedema With Eosinophilia in a Young Lactating Woman.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sustainable Effects of Human Dental Pulp Stem Cell Transplantation on Diabetic Polyneuropathy in Streptozotocine-Induced Type 1 Diabetes Model Mice.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemerin promotes angiogenesis in vivo.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transplantation of dental pulp stem cells improves long-term diabetic polyneuropathy together with improvement of nerve morphometrical evaluation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of poly(ADP-ribose) polymerase activation in the pathogenesis of periodontitis in diabetes.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Muscle-derived follistatin-like 1 function to reduce neointimal formation after vascular injury.2014

Author(s)

Miyabe Megumi 宮部愛

MIYABE Megumi 宮部愛