Jeong Hee-Jin 鄭煕陳

Researcher Number	70737981
Affiliation (based on the past Project Information) *help	2017: 東京工業大学, 資源化学研究所, 助教 2015: 東京工業大学, 資源化学研究所, 助教 2014: 東京工業大学, 資源化学研究所, 特任助教
Review Section/Research Field	Principal Investigator Biofunction/Bioprocess Except Principal Investigator Biofunction/Bioprocess
Keywords	Principal Investigator 生細胞イメージング / 蛍光解除 / 抗体工学 / 蛋白質工学 / 細胞イメージング / 免疫センサー / クローディン / クエンチボディー Except Principal Investigator タンパク質 / マイクロアレイ … More / プロテオーム / 免疫学 / 蛋白質 / 結合タンパク質 / 部位特異的修飾 / ケミカルバイオロジー / クエンチ / 蛍光 / 抗原 / 抗体 / バイオテクノロジー / バイオセンサー Less

Development of innovative immunoassay through the application of quench-release principle to natural antibodies
- Principal Investigator
  
  UEDA Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tokyo Institute of Technology
Development of Quenchbody to image and quantify tumor-associated membrane protein claudinPrincipal Investigator
- Principal Investigator
  
  Jeong Hee-Jin
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tokyo Institute of Technology

All 2018 2017 2016 2015 Other

All Journal Article Presentation Patent

[Journal Article] Preparation of Quenchbodies by protein transamination reaction（アミノ基転移反応によるクエンチ抗体の調製）2018
- Author(s)
  董金華, 鄭熙陳, 上田　宏
- Journal Title
  
  生物工学
  
  Volume: 96 Pages: 69-69
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04191
[Journal Article] Construction of dye-stapled Quenchbodies by photochemical crosslinking to antibody nucleotide-binding sites2017
- Author(s)
  Jeong Hee-Jin、Matsumoto Kenji、Itayama Shuya、Kodama Kozue、Abe Ryoji、Dong Jinhua、Shindo Mitsuru、Ueda Hiroshi
- Journal Title
  
  Chem. Commun.
  
  Volume: 53 Issue: 73 Pages: 10200-10203
- DOI
  10.1039/c7cc03043f
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01157, KAKENHI-PROJECT-15H04191
[Journal Article] Development of a Quenchbody for the Detection and Imaging of the Cancer-Related Tight-Junction-Associated Membrane Protein Claudin2017
- Author(s)
  Jeong Hee-Jin、Kawamura Takuya、Iida Manami、Kawahigashi Yumi、Takigawa Mutsumi、Ohmuro-Matsuyama Yuki、Chung Chan-I、Dong Jinhua、Kondoh Masuo、Ueda Hiroshi
- Journal Title
  
  Analytical Chemistry
  
  Volume: 89 Issue: 20 Pages: 10783-10789
- DOI
  10.1021/acs.analchem.7b02047
- NAID
  120006825608
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04191
[Journal Article] One-pot construction of Quenchbodies using antibody-binding proteins2016
- Author(s)
  Jeong Hee-Jin、Kojima Tomoki、Dong Jinhua、Ohashi Hiroyuki、Ueda Hiroshi
- Journal Title
  
  Analytical Methods
  
  Volume: 8 Issue: 43 Pages: 7774-7779
- DOI
  10.1039/c6ay02108e
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04191
[Journal Article] Q-bodies from recombinant single-chain Fv fragment with better yield and expanded palette of fluorophores2016
- Author(s)
  H.-J. Jeong, T. Kawamura, J. Dong and H. Ueda
- Journal Title
  
  ACS Sensors
  
  Volume: 1 Issue: 1 Pages: 88-94
- DOI
  10.1021/acssensors.5b00089
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04191
[Journal Article] Preparation of Quenchbodies by protein transamination reaction2016
- Author(s)
  Jinhua Dong, Hee-jin Jeong, Hiroshi Ueda
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 印刷中 Issue: 1 Pages: 504-509
- DOI
  10.1016/j.jbiosc.2015.12.010
- NAID
  40020886017
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26420793, KAKENHI-PROJECT-15H04191
[Journal Article] Insight into the Working Mechanism of Quenchbody: Transition of the Dye around Antibody Variable Region That Fluoresces upon Antigen Binding2016
- Author(s)
  Hiroyuki Ohashi, Toshio Matsumoto, Hee-JinJeong, Jinhua Dong,Ryoji Abe, Hiroshi Ueda
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 27(10) Issue: 10 Pages: 2248-2253
- DOI
  10.1021/acs.bioconjchem.6b00217
- NAID
  120006795377
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26420793, KAKENHI-PROJECT-15H04191
[Journal Article] ネオバイオ分子としてのQ-body2016
- Author(s)
  上田宏, 董金華, 鄭熙陳, 阿部亮二
- Journal Title
  
  生物工学会誌
  
  Volume: 94 Pages: 489-491
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04191
[Patent] 抗体のヌクレオチド結合部位（NBS)を利用して蛍光標識された抗体2015
- Inventor(s)
  上田宏，鄭熙陳，董金華，阿部亮二
- Industrial Property Rights Holder
  東京工業大学，ウシオ電機
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-03
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] 蛍光抗体バイオセンサーQuenchbodyを用いたがん細胞検出と治療の試み2017
- Author(s)
  岡裕也, 鄭煕陳, 董金華, 上田宏
- Organizer
  化学工学会第82年会
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] 天然抗体をQuenchbody化するための抗体結合蛍光プローブの開発2017
- Author(s)
  三宅千絢, 鄭煕陳, 大室有紀, 董金華, 上田宏
- Organizer
  化学工学会第82年会
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] Detection and destruction of Her2 positive cancer cells by Quenchbody-siRNA complex2017
- Author(s)
  Hiroshi Ueda, Hee-Jin Jeong, Jinhua Dong, Yuya Oka
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] 蛍光免疫センサーQ-body迅速構築のための新しい戦略2017
- Author(s)
  上田宏, 三宅千絢, 塚原知也, 高橋昌樹, 児島智樹, 鄭熙陳, 北口哲也, 董金華, 大橋広行
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] 蛍光免疫センサーQuenchbodyを用いたがん抗原蛋白質HER2の検出2016
- Author(s)
  岡裕也，鄭熙陳，董金華，上田宏
- Organizer
  化学工学会第81年会
- Place of Presentation
  関西大学千里山キャンパス
- Year and Date
  2016-03-13
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] Antibody-based Fluorescent Probes: How Can We Convert Antigen Binding Signal to Fluorescence Signal?2016
- Author(s)
  Hiroshi Ueda, Yuya Oka, Chan-I Chung, Hee-Jin Jeong, Jinhua Dong
- Organizer
  Third FB3 (Fluorescent Biomolecules and their Building Blocks) Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] Development of Fluorescent Antibody Quenchbodies to Detect Tumor-Associated Membrane Protein Claudin2015
- Author(s)
  ジョンヒジン
- Organizer
  第１５回日本蛋白質科学会年会
- Place of Presentation
  徳島市あわぎんホール
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26889028
[Presentation] 抗体タンパク質からの蛍光免疫センサーQuenchbodyの構築2015
- Author(s)
  上田宏，鄭熙陳，松本健司，板山修也，阿部亮二，董金華，新藤充
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H04191
[Presentation] がん関連膜タンパク質クローディン高感度検出のための蛍光抗体プローブの開発2015
- Author(s)
  河村拓哉, 飯田愛未, 川東祐美, 滝川睦美, 鍾蝉伊, 鄭煕陳, 董金華, 近藤昌夫, 上田宏
- Organizer
  化学工学会第80年会
- Place of Presentation
  芝浦工業大学
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-26889028
[Presentation] がん関連膜蛋白質クローディンを認識するQuenchbodyの開発
- Author(s)
  鄭煕陳, 河村拓哉, 飯田愛未, 川東祐美, 滝川睦美, 鍾蝉伊, 董金華, 近藤昌夫, 上田宏
- Organizer
  第15回蛋白質科学会年会
- Place of Presentation
  徳島大学
- Year and Date
  2015-06-24 – 2015-06-26
- Data Source
  KAKENHI-PROJECT-26889028

1. UEDA Hiroshi (60232758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. KOBAYASHI Norihiro (90205477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 大室有紀 (30571088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 董金華 (80527838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. 新藤充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 松山有紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Jeong Hee-Jin 鄭 煕陳

Research Projects

Research Products

Co-Researchers

Development of innovative immunoassay through the application of quench-release principle to natural antibodies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Quenchbody to image and quantify tumor-associated membrane protein claudinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Preparation of Quenchbodies by protein transamination reaction（アミノ基転移反応によるクエンチ抗体の調製）2018

Author(s)

Journal Title

Data Source

[Journal Article] Construction of dye-stapled Quenchbodies by photochemical crosslinking to antibody nucleotide-binding sites2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Quenchbody for the Detection and Imaging of the Cancer-Related Tight-Junction-Associated Membrane Protein Claudin2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] One-pot construction of Quenchbodies using antibody-binding proteins2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Q-bodies from recombinant single-chain Fv fragment with better yield and expanded palette of fluorophores2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preparation of Quenchbodies by protein transamination reaction2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Insight into the Working Mechanism of Quenchbody: Transition of the Dye around Antibody Variable Region That Fluoresces upon Antigen Binding2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] ネオバイオ分子としてのQ-body2016

Author(s)

Journal Title

Data Source

[Patent] 抗体のヌクレオチド結合部位（NBS)を利用して蛍光標識された抗体2015

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] 蛍光抗体バイオセンサーQuenchbodyを用いたがん細胞検出と治療の試み2017

Author(s)

Organizer

Data Source

[Presentation] 天然抗体をQuenchbody化するための抗体結合蛍光プローブの開発2017

Author(s)

Organizer

Data Source

[Presentation] Detection and destruction of Her2 positive cancer cells by Quenchbody-siRNA complex2017

Author(s)

Organizer

Data Source

[Presentation] 蛍光免疫センサーQ-body迅速構築のための新しい戦略2017

Author(s)

Organizer

Data Source

[Presentation] 蛍光免疫センサーQuenchbodyを用いたがん抗原蛋白質HER2の検出2016

Jeong Hee-Jin 鄭煕陳