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SASAKI KATSUHIRO  佐々木 克博

ORCIDConnect your ORCID iD *help
Researcher Number 70739862
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help 2018 – 2022: 京都大学, 医学研究科, 講師
2016 – 2017: 京都大学, 医学研究科, 特定研究員
Review Section/Research Field
Principal Investigator
Basic Section 49010:Pathological biochemistry-related / Basic Section 49030:Experimental pathology-related / Experimental pathology
Keywords
Principal Investigator
免疫 / LUBAC / 細胞死 / 炎症 / 制御性T細胞 / 自己炎症 / 自己免疫 / Treg / T細胞 / M1-Ub … More / サイトカイン / 癌免疫 / ネクローシス / 癌内炎症 / 炎症寛容 / 癌 / 直鎖状ユビキチン鎖 / ユビキチン / T細胞 / TNF / ユビキチンリガーゼ / 細胞死誘導 / 免疫学 / SHARPIN / 自己炎症性疾患 / 自己免疫疾患 / Sharpin / cpdm Less
  • Research Projects

    (3 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (3 People)
  •  Targeting of LUBAC-dependent inflammatory adaptation for the cancer therapyPrincipal Investigator

    • Principal Investigator
      SASAKI Katsuhiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Kyoto University
  •  T cell-induced autoinflammatory diseasesPrincipal Investigator

    • Principal Investigator
      Sasaki Katsuhiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  A role of anti-inflammatory T cell subset on LUBAC-deficient autoinflammatory diseasesPrincipal Investigator

    • Principal Investigator
      SASAKI KATSUHIRO
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University

All 2023 2022 2021 2020 2019 2017 2016

All Journal Article Presentation

  • [Journal Article] Differential involvement of <scp>LUBAC</scp> ‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation2022

    • Author(s)
      Sakamoto Yusuke、Sasaki Katsuhiro、Omatsu Mayuki、Hamada Kensuke、Nakanishi Yuki、Itatani Yoshiro、Kawada Kenji、Obama Kazutaka、Seno Hiroshi、Iwai Kazuhiro
    • Journal Title

      The Journal of Pathology

      Volume: 259 Issue: 3 Pages: 304-317

    • DOI

      10.1002/path.6042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20K07337, KAKENHI-PLANNED-18H05499
  • [Journal Article] ABIN1 is a signal‐induced autophagy receptor that attenuates NF‐κB activation by recognizing linear ubiquitin chains2022

    • Author(s)
      Shinkawa Y, Imami K, Fuseya Y, Sasaki K, Ohmura K, Ishihama Y, Morinobu A, Iwai K.
    • Journal Title

      FEBS Letters

      Volume: In press Issue: 9 Pages: 1147-1164

    • DOI

      10.1002/1873-3468.14323

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05499, KAKENHI-PUBLICLY-20H04844, KAKENHI-PUBLICLY-21H05720, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-22K15379
  • [Journal Article] Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia2022

    • Author(s)
      Jimbo Koji、Hattori Ayuna、Koide Shuhei、Ito Takahiro、Sasaki Katsuhiro、Iwai Kazuhiro、Nannya Yasuhito、Iwama Atsushi、Tojo Arinobu、Konuma Takaaki
    • Journal Title

      Leukemia

      Volume: 37 Issue: 1 Pages: 122-133

    • DOI

      10.1038/s41375-022-01750-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-22K16317, KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-20K08748
  • [Journal Article] Role of linear ubiquitination in inflammatory responses and tissue homeostasis2022

    • Author(s)
      Sasaki Katsuhiro、Iwai Kazuhiro
    • Journal Title

      International Immunology

      Volume: 35 Issue: 1 Pages: 19-25

    • DOI

      10.1093/intimm/dxac047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499
  • [Journal Article] LUBAC, the E3 ligase complex generating linear polyubiquitin chains2020

    • Author(s)
      佐々木克博、岩井一宏
    • Journal Title

      生化学

      Volume: 92 Issue: 1 Pages: 20-27

    • DOI

      10.14952/SEIKAGAKU.2020.920020

    • ISSN
      0037-1017
    • Year and Date
      2020-02-25
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15118, KAKENHI-ORGANIZER-18H05497
  • [Journal Article] Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.2019

    • Author(s)
      Sasaki, K., Himeno, A., Nakagawa, T., Sasaki, Y., Kiyonari, H. and Iwai, K.
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 3878-3878

    • DOI

      10.1038/s41467-019-11858-7

    • NAID

      120006716601

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08880, KAKENHI-PROJECT-18K15118, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-17H06174
  • [Presentation] 直鎖状ユビキチン鎖翻訳後修飾に基づいた炎症環境適応機構2023

    • Author(s)
      佐々木 克博
    • Organizer
      がん研究会セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07337
  • [Presentation] 直鎖状ユビキチン鎖シグナルが創り出す病的・恒常的炎症環境2022

    • Author(s)
      佐々木 克博
    • Organizer
      第95回日本生化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07337
  • [Presentation] 癌進展を加速させる炎症駆動型直鎖状ユビキチン修飾機構2021

    • Author(s)
      佐々木克博、早水慶恵、岩井一宏
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07337
  • [Presentation] An autoinflammatory mechanism by TNF-expressing T cells2019

    • Author(s)
      Katsuhiro Sasaki and Kazuhiro Iwai
    • Organizer
      17th TNF conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15118
  • [Presentation] 直鎖状ユビキチン鎖生成酵素LUBACによる免疫恒常性維持と炎症制御2017

    • Author(s)
      佐々木 克博
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)ワークショップ
    • Data Source
      KAKENHI-PROJECT-16K19106
  • [Presentation] LUBAC deficiency of regulatory T cells induces autoinflammatory-like pathology as an alternative autoimmune manifestation2016

    • Author(s)
      Katsuhiro Sasaki, Kazuhiro Iwai
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16K19106
  • [Presentation] SHARPIN欠損マウスにおける免疫恒常性の破綻2016

    • Author(s)
      佐々木 克博
    • Organizer
      第8回シグナルネットワーク研究会
    • Place of Presentation
      大阪大学微生物病研究所(大阪府吹田市)
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-16K19106
  • 1.  岩井 一宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 2.  佐々木 義輝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  小出 周平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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