SASAKI KATSUHIRO 佐々木克博

Researcher Number	70739862
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2018 – 2022: 京都大学, 医学研究科, 講師 2016 – 2017: 京都大学, 医学研究科, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Basic Section 49030:Experimental pathology-related / Experimental pathology
Keywords	Principal Investigator 免疫 / LUBAC / 細胞死 / 炎症 / 制御性T細胞 / 自己炎症 / 自己免疫 / Treg / T細胞 / M1-Ub … More / サイトカイン / 癌免疫 / ネクローシス / 癌内炎症 / 炎症寛容 / 癌 / 直鎖状ユビキチン鎖 / ユビキチン / Ｔ細胞 / TNF / ユビキチンリガーゼ / 細胞死誘導 / 免疫学 / SHARPIN / 自己炎症性疾患 / 自己免疫疾患 / Sharpin / cpdm Less

Targeting of LUBAC-dependent inflammatory adaptation for the cancer therapyPrincipal Investigator
- Principal Investigator
  
  SASAKI Katsuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto University
T cell-induced autoinflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  Sasaki Katsuhiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kyoto University
A role of anti-inflammatory T cell subset on LUBAC-deficient autoinflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  SASAKI KATSUHIRO
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2017 2016

All Journal Article Presentation

[Journal Article] Differential involvement of <scp>LUBAC</scp> ‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation2022
- Author(s)
  Sakamoto Yusuke、Sasaki Katsuhiro、Omatsu Mayuki、Hamada Kensuke、Nakanishi Yuki、Itatani Yoshiro、Kawada Kenji、Obama Kazutaka、Seno Hiroshi、Iwai Kazuhiro
- Journal Title
  
  The Journal of Pathology
  
  Volume: 259 Issue: 3 Pages: 304-317
- DOI
  10.1002/path.6042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20K07337, KAKENHI-PLANNED-18H05499
[Journal Article] ABIN1 is a signal‐induced autophagy receptor that attenuates NF‐κB activation by recognizing linear ubiquitin chains2022
- Author(s)
  Shinkawa Y, Imami K, Fuseya Y, Sasaki K, Ohmura K, Ishihama Y, Morinobu A, Iwai K.
- Journal Title
  
  FEBS Letters
  
  Volume: In press Issue: 9 Pages: 1147-1164
- DOI
  10.1002/1873-3468.14323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05499, KAKENHI-PUBLICLY-20H04844, KAKENHI-PUBLICLY-21H05720, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-22K15379
[Journal Article] Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia2022
- Author(s)
  Jimbo Koji、Hattori Ayuna、Koide Shuhei、Ito Takahiro、Sasaki Katsuhiro、Iwai Kazuhiro、Nannya Yasuhito、Iwama Atsushi、Tojo Arinobu、Konuma Takaaki
- Journal Title
  
  Leukemia
  
  Volume: 37 Issue: 1 Pages: 122-133
- DOI
  10.1038/s41375-022-01750-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-22K16317, KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-20K08748
[Journal Article] Role of linear ubiquitination in inflammatory responses and tissue homeostasis2022
- Author(s)
  Sasaki Katsuhiro、Iwai Kazuhiro
- Journal Title
  
  International Immunology
  
  Volume: 35 Issue: 1 Pages: 19-25
- DOI
  10.1093/intimm/dxac047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499
[Journal Article] LUBAC, the E3 ligase complex generating linear polyubiquitin chains2020
- Author(s)
  佐々木克博、岩井一宏
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 20-27
- DOI
  10.14952/SEIKAGAKU.2020.920020
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15118, KAKENHI-ORGANIZER-18H05497
[Journal Article] Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.2019
- Author(s)
  Sasaki, K., Himeno, A., Nakagawa, T., Sasaki, Y., Kiyonari, H. and Iwai, K.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 3878-3878
- DOI
  10.1038/s41467-019-11858-7
- NAID
  120006716601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08880, KAKENHI-PROJECT-18K15118, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-17H06174
[Presentation] 直鎖状ユビキチン鎖翻訳後修飾に基づいた炎症環境適応機構2023
- Author(s)
  佐々木克博
- Organizer
  がん研究会セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K07337
[Presentation] 直鎖状ユビキチン鎖シグナルが創り出す病的・恒常的炎症環境2022
- Author(s)
  佐々木克博
- Organizer
  第95回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07337
[Presentation] 癌進展を加速させる炎症駆動型直鎖状ユビキチン修飾機構2021
- Author(s)
  佐々木克博、早水慶恵、岩井一宏
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07337
[Presentation] An autoinflammatory mechanism by TNF-expressing T cells2019
- Author(s)
  Katsuhiro Sasaki and Kazuhiro Iwai
- Organizer
  17th TNF conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15118
[Presentation] 直鎖状ユビキチン鎖生成酵素LUBACによる免疫恒常性維持と炎症制御2017
- Author(s)
  佐々木　克博
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）ワークショップ
- Data Source
  KAKENHI-PROJECT-16K19106
[Presentation] LUBAC deficiency of regulatory T cells induces autoinflammatory-like pathology as an alternative autoimmune manifestation2016
- Author(s)
  Katsuhiro Sasaki, Kazuhiro Iwai
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K19106
[Presentation] SHARPIN欠損マウスにおける免疫恒常性の破綻2016
- Author(s)
  佐々木　克博
- Organizer
  第8回シグナルネットワーク研究会
- Place of Presentation
  大阪大学微生物病研究所（大阪府吹田市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-16K19106

1. 岩井一宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 佐々木義輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 小出周平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAKI KATSUHIRO 佐々木 克博

Research Projects

Research Products

Co-Researchers

Targeting of LUBAC-dependent inflammatory adaptation for the cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

T cell-induced autoinflammatory diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A role of anti-inflammatory T cell subset on LUBAC-deficient autoinflammatory diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential involvement of <scp>LUBAC</scp> ‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ABIN1 is a signal‐induced autophagy receptor that attenuates NF‐κB activation by recognizing linear ubiquitin chains2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of linear ubiquitination in inflammatory responses and tissue homeostasis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LUBAC, the E3 ligase complex generating linear polyubiquitin chains2020

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 直鎖状ユビキチン鎖翻訳後修飾に基づいた炎症環境適応機構2023

Author(s)

Organizer

Data Source

[Presentation] 直鎖状ユビキチン鎖シグナルが創り出す病的・恒常的炎症環境2022

Author(s)

Organizer

Data Source

[Presentation] 癌進展を加速させる炎症駆動型直鎖状ユビキチン修飾機構2021

Author(s)

Organizer

Data Source

[Presentation] An autoinflammatory mechanism by TNF-expressing T cells2019

Author(s)

Organizer

Data Source

[Presentation] 直鎖状ユビキチン鎖生成酵素LUBACによる免疫恒常性維持と炎症制御2017

Author(s)

Organizer

Data Source

[Presentation] LUBAC deficiency of regulatory T cells induces autoinflammatory-like pathology as an alternative autoimmune manifestation2016

Author(s)

Organizer

Place of Presentation

SASAKI KATSUHIRO 佐々木克博