Sakamoto Akihiko 坂本明彦

… Alternative Names

坂本明彦サカモトアキヒコ

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Researcher Number	70740439
Other IDs	https://orcid.org/0000-0003-0788-3646
Affiliation (Current)	2024: 山口大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022: 金沢大学, 薬学系, 助教 2021: 金沢大学, 薬学系, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator S抗原 / COVID-19 / デルタ株 / COVID-19ワクチン / 純国産弱毒生ワクチン / メモリーT細胞 / 中和活性 / マウス / オミクロン株 / 新型コロナウイルス / プロモーター / ウイルスベクターワクチン … More Except Principal Investigator … More 感染防御 / 中和活性 / アデノ随伴ウイルス / ワクシニアウイルス / ワクチン / COVID-19 Less

Versatile next-generation vaccine platform -Application for COVID-19-
- Principal Investigator
  
  吉田栄人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kanazawa University
Development of novel heterologous virus-vectored vaccines for COVID-19Principal Investigator
- Principal Investigator
  
  坂本明彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kanazawa University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Adeno-associated virus-based malaria booster vaccine following attenuated replication-competent vaccinia virus LC16m8Δ priming2023
- Author(s)
  Hasyim Ammar A.、Iyori Mitsuhiro、Mizuno Tetsushi、Abe Yu-ichi、Yamagoshi Iroha、Yusuf Yenni、Syafira Intan、Shahnaij Mohammad、Sakamoto Akihiko、Yamamoto Yutaro、Mizukami Hiroaki、Shida Hisatoshi、Yoshida Shigeto
- Journal Title
  
  Parasitology International
  
  Volume: 92 Pages: 102652-102652
- DOI
  10.1016/j.parint.2022.102652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-22K19374
[Journal Article] A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine2022
- Author(s)
  Sakamoto Akihiko、Osawa Hiroaki、Hashimoto Hinata、Mizuno Tetsushi、Hasyim Ammar A.、Abe Yu-ichi、Okahashi Yuto、Ogawa Ryohei、Iyori Mitsuhiro、Shida Hisatoshi、Yoshida Shigeto
- Journal Title
  
  Emerging Microbes & Infections
  
  Volume: 11 Issue: 1 Pages: 2359-2370
- DOI
  10.1080/22221751.2022.2122580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-22K19374
[Journal Article] Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study2022
- Author(s)
  Iyori Mitsuhiro、Blagborough Andrew M.、Mizuno Tetsushi、Abe Yu-ichi、Nagaoka Mio、Hori Naoto、Yamagoshi Iroha、Da Dari F.、Gregory William F.、Hasyim Ammar A.、Yamamoto Yutaro、Sakamoto Akihiko、Yoshida Kunitaka、Mizukami Hiroaki、Shida Hisatoshi、Yoshida Shigeto
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 1-13
- DOI
  10.3389/fimmu.2022.1005476
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545, KAKENHI-PROJECT-21K06559, KAKENHI-PROJECT-22K19374
[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023
- Author(s)
  水野哲志、Blagborough Andrew、新倉保、Hasyim Ammar A.、伊從光洋、山本祐太朗、坂本明彦、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023
- Author(s)
  Hasyim Ammar A.、水野哲志、阿部優一、山越彩葉、Yusuf Yenni、Syafira Intan、坂本明彦、山本祐太朗、伊從光洋、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 感染防御・伝播阻止両機能を有する次世代型三日熱マラリアマルチステージワクチン開発研究2023
- Author(s)
  山本祐太朗、Fabbri Camila、奥原大輝、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、水野哲志、Lopes Stefanie、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023
- Author(s)
  Hasyim Ammar A.、水野哲志、阿部優一、山越彩葉、Yusuf Yenni、Syafira Intan、坂本明彦、山本祐太朗、伊從光洋、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 熱帯熱マラリアワクチンLC16m8Δ/AAV-Pf(s25-CSP)のエピトープ変異原虫に対する感染防御効果の評価（マウスモデル）2023
- Author(s)
  奥山竣介、山本祐太朗、村井駿介、金村若葉、水野哲志、坂本明彦、伊從光洋、福本晋也、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 感染防御・伝播阻止両機能を有する次世代型三日熱マラリアマルチステージワクチン開発研究2023
- Author(s)
  山本祐太朗、Fabbri Camila、奥原大輝、片山拓和、坂本明彦、水上浩明、志田壽利、伊從光洋、水野哲志、Lopes Stefanie、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 熱帯熱マラリア・COVID-19・サル痘に有効な3価ワクチンの開発研究2023
- Author(s)
  佐藤侑奈、山本祐太朗、坂本明彦、伊從光洋、森田武志、渡士幸一、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 熱帯熱マラリア・COVID-19・サル痘に有効な3価ワクチンの開発研究2023
- Author(s)
  佐藤侑奈、山本祐太朗、坂本明彦、伊從光洋、森田武志、渡士幸一、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 熱帯熱マラリアワクチンLC16m8Δ/AAV-Pf(s25-CSP)のエピトープ変異原虫に対する感染防御効果の評価（マウスモデル）2023
- Author(s)
  奥山竣介、山本祐太朗、村井駿介、金村若葉、水野哲志、坂本明彦、伊從光洋、福本晋也、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023
- Author(s)
  水野哲志、Blagborough Andrew、新倉保、Hasyim Ammar A.、伊從光洋、山本祐太朗、坂本明彦、水上浩明、志田壽利、吉田栄人
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 弱毒・増殖性ワクシニアウイルスをベクターとするCOVID-19ワクチンの開発2022
- Author(s)
  橋本ひなた、坂本明彦、大澤弘明、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Improved immunogenicity of the recombinant vaccinia virus by targeting the immunomodulatory A46R gene locus2022
- Author(s)
  坂本明彦、橋本ひなた、大澤弘明、山内彩椰、水野哲志、山形恭平、三橋慧吾、小川良平、車京儒、伊從光洋、志田壽利、吉田栄人
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Optimization of Plasmodium falciparum multistage vaccine based on the heterologous viral-vectored platform in a murine mod2022
- Author(s)
  Miyabe Ryo, Yamamoto Yutaro, Zainal Kartika H., Hasyim Ammar A., Abe Yu-ichi, Iyori Mitsuhiro, Mizuno Tetsushi, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 弱毒・増殖性ワクシニアウイルスをベクターとするCOVID-19ワクチンの開発2022
- Author(s)
  橋本ひなた、坂本明彦、大澤弘明、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] A Novel Malaria Multistage Vaccine Based on Vaccinia virus-Prime/AAV5-Boost Elicits Sterile Protection and Transmission Blocking Efficacy2022
- Author(s)
  Hasyim Ammar A., Iyori Mitsuhiro, Mizuno Tetsushi, Abe Yu-ichi, Mizukami Hiroaki, Yamagoshi Iroha, Yusuf Yenni, Syafira Intan, Sakamoto Akihiko, Yamamoto Yutaro, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 国産種痘ワクチンをベクターとしたCOVID-19ワクチンは中和抗体・細胞性免疫応答を効果的に誘導（マウスモデル）2022
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] 国産種痘ワクチンをベクターとしたCOVID-19ワクチンは中和抗体・細胞性免疫応答を効果的に誘導（マウスモデル）2022
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、小川良平、三橋慧吾、山内彩椰、山形恭平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Improved immunogenicity of the recombinant vaccinia virus by targeting the immunomodulatory A46R gene locus2022
- Author(s)
  坂本明彦、橋本ひなた、大澤弘明、山内彩椰、水野哲志、山形恭平、三橋慧吾、小川良平、車京儒、伊從光洋、志田壽利、吉田栄人
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] A Novel Malaria Multistage Vaccine Based on Vaccinia virus-Prime/AAV5-Boost Elicits Sterile Protection and Transmission Blocking Efficacy2022
- Author(s)
  Hasyim Ammar A., Iyori Mitsuhiro, Mizuno Tetsushi, Abe Yu-ichi, Mizukami Hiroaki, Yamagoshi Iroha, Yusuf Yenni, Syafira Intan, Sakamoto Akihiko, Yamamoto Yutaro, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Pre-erythrocytic and transmission-blocking multi-stage malaria vaccine strategy shows a strong synergic effect to control malaria disease2022
- Author(s)
  Mizuno Tetsushi, Blagborough Andrew M., Niikura Mamoru, Hasyim Ammar A., Iyori Mitsuhiro, Yamamoto Yutaro, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shiget
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Availability of the highly attenuated replication-competent vaccinia virus strain LC16m8Δ as a COVID-19 vaccine platfo2022
- Author(s)
  Sakamoto Akihiko、Osawa Hiroaki、Mizuno Tetsushi、Hashimoto Hinata、Yamagata Kyouhei、Yamauchi Saya、Mitsuhashi Keigo、Ogawa Ryohei、Iyori Mitsuhiro、Shida Hisatoshi、Yoshida Shigeto
- Organizer
  16th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Plasmodium vivax multistage vaccine based on the heterologous viral-vectored platform achieves sterile protection and transmission blocking2022
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Okuhara Daiki、Katayama Takuto、Takagi Rina、Kawabata Yuna、Iyori Mitsuhiro、Mizuno Tetsushi、Sakamoto Akihiko、Hasyim Ammar A.、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Plasmodium vivax multistage vaccine based on the heterologous viral-vectored platform achieves sterile protection and transmission blocking2022
- Author(s)
  Yamamoto Yutaro、Fabbri Camila、Okuhara Daiki、Katayama Takuto、Takagi Rina、Kawabata Yuna、Iyori Mitsuhiro、Mizuno Tetsushi、Sakamoto Akihiko、Hasyim Ammar A.、Mizukami Hiroaki、Shida Hisatoshi、Lopes Stefanie、Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19374
[Presentation] Optimization of Plasmodium falciparum multistage vaccine based on the heterologous viral-vectored platform in a murine model2022
- Author(s)
  Miyabe Ryo, Yamamoto Yutaro, Zainal Kartika H., Hasyim Ammar A., Abe Yu-ichi, Iyori Mitsuhiro, Mizuno Tetsushi, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Pre-erythrocytic and transmission-blocking multi-stage malaria vaccine strategy shows a strong synergic effect to control malaria disease2022
- Author(s)
  Mizuno Tetsushi, Blagborough Andrew M., Niikura Mamoru, Hasyim Ammar A., Iyori Mitsuhiro, Yamamoto Yutaro, Sakamoto Akihiko, Mizukami Hiroaki, Shida Hisatoshi, Yoshida Shigeto
- Organizer
  ASTMH 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] Availability of the highly attenuated replication-competent vaccinia virus strain LC16m8Δ as a COVID-19 vaccine platform2022
- Author(s)
  Sakamoto Akihiko、Osawa Hiroaki、Mizuno Tetsushi、Hashimoto Hinata、Yamagata Kyouhei、Yamauchi Saya、Mitsuhashi Keigo、Ogawa Ryohei、Iyori Mitsuhiro、Shida Hisatoshi、Yoshida Shigeto
- Organizer
  16th Vaccine Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 純国産弱毒生ワクチンをベクターとした新規COVID-19ワクチンはマウスモデルでS-偽型ウイルスに対して中和抗体を誘導する2021
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、阿部優一、小川良平、伊從光洋、志田壽利、吉田栄人
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06545
[Presentation] 次世代型COVID-19ワクチンの開発 -遺伝子組換えウイルスワクチンは高レベルでの中和抗体を誘導-2021
- Author(s)
  大澤弘明、坂本明彦、橋本ひなた、水野哲志、阿部優一、小川良平、伊從光洋、志田壽利、吉田栄人
- Organizer
  日本薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-21K06545

1. 吉田栄人 (10296121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 水野哲志 (60882230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results

Sakamoto Akihiko 坂本 明彦

坂本 明彦 サカモト アキヒコ

Research Projects

Research Products

Co-Researchers

Versatile next-generation vaccine platform -Application for COVID-19-

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel heterologous virus-vectored vaccines for COVID-19Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Adeno-associated virus-based malaria booster vaccine following attenuated replication-competent vaccinia virus LC16m8Δ priming2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023

Author(s)

Organizer

Data Source

[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023

Author(s)

Organizer

Data Source

[Presentation] 感染防御・伝播阻止両機能を有する次世代型三日熱マラリアマルチステージワクチン開発研究2023

Author(s)

Organizer

Data Source

[Presentation] Multistage malaria booster vaccine based on Adeno-associated virus serotype 5 induces sterile protection and blocks parasite transmission2023

Author(s)

Organizer

Data Source

[Presentation] 熱帯熱マラリアワクチンLC16m8Δ/AAV-Pf(s25-CSP)のエピトープ変異原虫に対する感染防御効果の評価（マウスモデル）2023

Author(s)

Organizer

Data Source

[Presentation] 感染防御・伝播阻止両機能を有する次世代型三日熱マラリアマルチステージワクチン開発研究2023

Author(s)

Organizer

Data Source

[Presentation] 熱帯熱マラリア・COVID-19・サル痘に有効な3価ワクチンの開発研究2023

Author(s)

Organizer

Data Source

[Presentation] 熱帯熱マラリア・COVID-19・サル痘に有効な3価ワクチンの開発研究2023

Author(s)

Organizer

Data Source

[Presentation] 熱帯熱マラリアワクチンLC16m8Δ/AAV-Pf(s25-CSP)のエピトープ変異原虫に対する感染防御効果の評価（マウスモデル）2023

Author(s)

Organizer

Data Source

[Presentation] The synergy of the multi-stage vaccine against Plasmodium falciparum enhances the reduction of parasite prevalence in a murine model2023

Author(s)

Organizer

Data Source

[Presentation] 弱毒・増殖性ワクシニアウイルスをベクターとするCOVID-19ワクチンの開発2022

Author(s)

Organizer

Data Source

[Presentation] Improved immunogenicity of the recombinant vaccinia virus by targeting the immunomodulatory A46R gene locus2022

Author(s)

Organizer

Data Source

Sakamoto Akihiko 坂本明彦

坂本明彦サカモトアキヒコ