Ishizaka Aya 石坂彩

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ISHIZAKA Aya 石坂彩

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Researcher Number	70746859
Other IDs	https://orcid.org/0000-0003-2800-2430
Affiliation (Current)	2025: 東京大学, 医科学研究所, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京大学, 医科学研究所, 助教 2017 – 2018: 東京大学, 医科学研究所, 特任研究員 2016: 公益財団法人微生物化学研究会, 微生物化学研究所, 博士研究員 2015: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員
Review Section/Research Field	Principal Investigator Virology / Basic Section 54030:Infectious disease medicine-related / 0904:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 慢性炎症 / HIV / 腸内細菌叢 / 細胞外小胞 / 潜伏感染 / 免疫活性化 / 腸内細菌 / ウィルス / 残存感染細胞

Mechanism of maintenance of chronic inflammation mediated by extracellular vesicles derived from gut microbiomePrincipal Investigator
- Principal Investigator
  
  石坂彩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  The University of Tokyo
腸内細菌の異所性感染に着目したHIV持続感染の慢性炎症維持機構の解析Principal Investigator
- Principal Investigator
  
  石坂彩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  The University of Tokyo
Analysis of inflammatory mechanisms associated with HIVPrincipal Investigator
- Principal Investigator
  
  Ishizaka Aya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Identification of host factors associated with persistent transactivation of HIVPrincipal Investigator
- Principal Investigator
  
  ISHIZAKA Aya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Microbial Chemistry Research Foundation

All 2024 2023 2019 2016 2015

All Journal Article Presentation Patent

[Journal Article] Longitudinal analysis of microbiome composition in Ghanaians living with HIV-12024
- Author(s)
  Runtuwene Lucky Ronald、Parbie Prince Kofi、Mizutani Taketoshi、Ishizaka Aya、Matsuoka Saori、Abana Christopher Zaab-Yen、Kushitor Dennis、Bonney Evelyn Yayra、Ofori Sampson Badu、Kiyono Hiroshi、Ishikawa Koichi、Ampofo William Kwabena、Matano Tetsuro
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 15 Pages: 1359402-1359402
- DOI
  10.3389/fmicb.2024.1359402
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20926, KAKENHI-PROJECT-21H02745
[Journal Article] Association of gut microbiota with the pathogenesis of SARS-CoV-2 Infection in people living with HIV2024
- Author(s)
  Ishizaka Aya、Koga Michiko、Mizutani Taketoshi、Yamayoshi Seiya、Iwatsuki-Horimoto Kiyoko、Adachi Eisuke、Suzuki Yutaka、Kawaoka Yoshihiro、Yotsuyanagi Hiroshi
- Journal Title
  
  BMC Microbiology
  
  Volume: 24 Issue: 1 Pages: 6-6
- DOI
  10.1186/s12866-023-03157-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K20926, KAKENHI-PROJECT-21K07314, KAKENHI-PROJECT-21K11592
[Journal Article] Antibody induction and immune response in nasal cavity by third dose of SARS-CoV-2 mRNA vaccination2023
- Author(s)
  Ishizaka Aya、Koga Michiko、Mizutani Taketoshi、Uraki Ryuta、Yamayoshi Seiya、Iwatsuki-Horimoto Kiyoko、Yamamoto Shinya、Imai Masaki、Tsutsumi Takeya、Suzuki Yutaka、Kawaoka Yoshihiro、Yotsuyanagi Hiroshi
- Journal Title
  
  Virology Journal
  
  Volume: 20 Issue: 1 Pages: 146-146
- DOI
  10.1186/s12985-023-02113-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K20926, KAKENHI-PROJECT-21K07314, KAKENHI-PROJECT-21K11592
[Journal Article] Short intracellular HIV-1 transcripts as biomarkers of residual immune activation in patients on antiretroviral therapy.2016
- Author(s)
  A. Ishizaka, H. Sato, H. Nakamura, M. Koga, T. Kikuchi, N. Hosoya, T. Koibuchi, A. Nomoto, A. Kawana-Tachikawa and T. Mizutani
- Journal Title
  
  Journal of Virology
  
  Volume: 未確定 Issue: 12 Pages: 5665-76
- DOI
  10.1128/jvi.03158-15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19117, KAKENHI-PROJECT-15K12694
[Journal Article] Transferrin Receptor 1 Facilitates Poliovirus Permeation of Mouse Brain Capillary Endothelial Cells.2016
- Author(s)
  Mizutani T, Ishizaka A, Nihei C.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 6 Pages: 2829-2836
- DOI
  10.1074/jbc.m115.690941
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14413, KAKENHI-PROJECT-26670204, KAKENHI-PROJECT-15K19117
[Journal Article] The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters2015
- Author(s)
  Mizutani T, Ishizaka A, Furuichi Y
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 30 Pages: 18391-18399
- DOI
  10.1074/jbc.m115.657155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19117
[Patent] 免疫状態の判定方法、ＣＤ４＋Ｔ細胞数の増加予測方法、及びＣＤ４＋Ｔ細胞数の減少予測方法、並びにそれらのためのキット2015
- Inventor(s)
  水谷壮利、石坂彩、立川愛
- Industrial Property Rights Holder
  公益財団法人微生物化学研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2015-10-07
- Overseas
- Data Source
  KAKENHI-PROJECT-15K19117
[Presentation] Gut-Microbiome Changes Over 4 Years in PLWH With Good Immune Status on ART.2024
- Author(s)
  Aya Ishizaka, Michiko Koga, Taketoshi Mizutani, Hiroshi Yotsuyanagi
- Organizer
  CROI 2024 (The 31st Conference on Retroviruses and Opportunistic Infection)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20926
[Presentation] HIV感染者における腸内細菌叢の時間変化と体重増加の関係2023
- Author(s)
  水谷壮利, 石坂彩, 古賀道子, 水谷壮利, 四柳宏
- Organizer
  第37回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K20926
[Presentation] 薬害被害者が悪性腫瘍に罹患した際の心理的支援についてのアンケート調査2023
- Author(s)
  福田あかり, 古賀道子, 田中貴大, 石坂彩, 保坂隆, 四柳宏
- Organizer
  第37回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K20926
[Presentation] 腸内細菌由来の細胞外小胞の分離と炎症惹起におけるその生理機能の解明2023
- Author(s)
  石坂彩, 古賀道子, 水谷壮利, 四柳宏
- Organizer
  第10回日本細胞小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-22K20926
[Presentation] HIV感染者における腸内細菌叢の時間変化と体重増加の関係2023
- Author(s)
  石坂彩, 古賀道子, 水谷壮利, 四柳宏
- Organizer
  第37回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K20926
[Presentation] 非加熱血液凝固因子製剤によるHIV感染血友病等患者に合併する腫瘍に関する研究2023
- Author(s)
  古賀道子, 福田あかり, 石坂彩, 田中貴大, 保坂隆, 伊藤俊広, 江口晋, 遠藤知之, 柿沼章子, 木内英, 後藤智巳, 高橋俊二, 武田飛呂城, 照屋勝治, 花井十五, 藤井輝久, 藤谷順子, 三田英治, 南留美, 茂呂寛, 横幕能行, 渡邊大, 渡邊珠代, 四柳宏
- Organizer
  第37回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K20926
[Presentation] Short transcriptを指標とした残存感染細胞の性状解析2019
- Author(s)
  石坂彩、古賀道子、佐藤秀憲、菊地正、安達英輔、鯉渕智彦、四柳宏、清野宏、立川（川名）愛、水谷壮利
- Organizer
  第32回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K15705
[Presentation] Short intracellular HIV-1 transcripts serve as biomarkers of residual immune activation in patients on antiretroviral therapy2016
- Author(s)
  Aya Ishizaka, Hidenori Sato, Hitomi Nakamura, Michiko Koga, Tomohiko Koibuchi, Ai Kawana-Tachikawa and Taketoshi Mizutani
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  くまもと県民交流館パレア（熊本県熊本市）
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19117
[Presentation] Cell associated HIV RNA (Short Transcripts)とT細胞活性化との関連2016
- Author(s)
  石坂彩、佐藤秀憲、中村仁美、古賀道子、鯉渕智彦、立川（川名）愛、水谷壮利
- Organizer
  第30回日本エイズ学会学術集会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K19117

1. 水谷壮利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishizaka Aya 石坂 彩

ISHIZAKA Aya 石坂 彩

Research Projects

Research Products

Co-Researchers

Mechanism of maintenance of chronic inflammation mediated by extracellular vesicles derived from gut microbiomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腸内細菌の異所性感染に着目したHIV持続感染の慢性炎症維持機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of inflammatory mechanisms associated with HIVPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of host factors associated with persistent transactivation of HIVPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Longitudinal analysis of microbiome composition in Ghanaians living with HIV-12024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of gut microbiota with the pathogenesis of SARS-CoV-2 Infection in people living with HIV2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibody induction and immune response in nasal cavity by third dose of SARS-CoV-2 mRNA vaccination2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Short intracellular HIV-1 transcripts as biomarkers of residual immune activation in patients on antiretroviral therapy.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transferrin Receptor 1 Facilitates Poliovirus Permeation of Mouse Brain Capillary Endothelial Cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters2015

Author(s)

Journal Title

DOI

Data Source

[Patent] 免疫状態の判定方法、ＣＤ４＋Ｔ細胞数の増加予測方法、 及びＣＤ４＋Ｔ細胞数の減少予測方法、並びにそれらのためのキット2015

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Gut-Microbiome Changes Over 4 Years in PLWH With Good Immune Status on ART.2024

Author(s)

Organizer

Data Source

[Presentation] HIV感染者における腸内細菌叢の時間変化と体重増加の関係2023

Author(s)

Organizer

Data Source

[Presentation] 薬害被害者が悪性腫瘍に罹患した際の心理的支援についてのアンケート調査2023

Author(s)

Organizer

Data Source

[Presentation] 腸内細菌由来の細胞外小胞の分離と炎症惹起におけるその生理機能の解明2023

Author(s)

Organizer

Ishizaka Aya 石坂彩

ISHIZAKA Aya 石坂彩

[Patent] 免疫状態の判定方法、ＣＤ４＋Ｔ細胞数の増加予測方法、及びＣＤ４＋Ｔ細胞数の減少予測方法、並びにそれらのためのキット2015