SAKURAI YOSHITAKA 桜井賛孝

… Alternative Names

Sakurai Yoshitaka 桜井賛孝

Less

Researcher Number	70748376
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 助教 2017 – 2023: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Pathological medical chemistry Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator ユビキチン / 膵β細胞 / インスリン分泌 / 糖尿病 / 糖尿病関連遺伝子 / インスリン / 肥満 / シグナル伝達 / インスリンシグナル / 肝癌 / インスリン受容体基質 … More Except Principal Investigator … More 膵β細胞 / インスリン分泌 / UBE2E2 / KCNQ1 / 疾患モデル動物 / 疾患感受性遺伝子 / 2型糖尿病 Less

2型糖尿病遺伝子KCNQ1の機能解析Principal Investigator
- Principal Investigator
  
  桜井賛孝
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  The University of Tokyo
糖代謝異常の病態形成における2型糖尿病遺伝子UBE2E2の役割Principal Investigator
- Principal Investigator
  
  桜井賛孝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  The University of Tokyo
Role of UBE2E2 in regulating pancreatic beta cell massPrincipal Investigator
- Principal Investigator
  
  Sakurai Yoshitaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  The University of Tokyo
Functional analysis of type 2 diabetes susceptibility genes using animal disease models
- Principal Investigator
  
  TAKAMOTO ISEKI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  International University of Health and Welfare
  Japan Association for Development of Community Medicine
Role of insulin receptor substrates in the progression of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Sakurai Yoshitaka
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] 医薬のあゆみ　Vol.286 No.10, 763-768.2023
- Author(s)
  桜井賛孝、山内敏正
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22K08620
[Journal Article] Bi-weekly Glycated Albumin Measurement was Useful to Encourage Behavioral Changes in People with Type 2 Diabetes Mellitus2023
- Author(s)
  Aihara Masakazu、Hayashi Takanori、Koizumi Chie、Sakurai Yoshitaka、Sawada Mika、Kubota Tetsuya、Kadowaki Takashi、Yamauchi Toshimasa、Kubota Naoto
- Journal Title
  
  Diabetes Therapy
  
  Volume: 14 Issue: 10 Pages: 1711-1721
- DOI
  10.1007/s13300-023-01452-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K16347
[Journal Article] Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass2023
- Author(s)
  Sakurai Yoshitaka、Kubota Naoto、Takamoto Iseki、Wada Nobuhiro、Aihara Masakazu、Hayashi Takanori、Kubota Tetsuya、Hiraike Yuta、Sasako Takayoshi、Nakao Harumi、Aiba Atsu、Chikaoka Yoko、Kawamura Takeshi、Kadowaki Takashi、Yamauchi Toshimasa
- Journal Title
  
  Diabetes
  
  Volume: 73 Issue: 3 Pages: 474-489
- DOI
  10.2337/db23-0150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-21K16347
[Journal Article] Evaluation of glycated albumin levels in tears and saliva as a marker in patients with diabetes mellitus2023
- Author(s)
  Aihara Masakazu、Jinnouchi Hideaki、Yoshida Akira、Ijima Hiroko、Sakurai Yoshitaka、Hayashi Takanori、Koizumi Chie、Kubota Tetsuya、Usami Satoshi、Yamauchi Toshimasa、Sakata Toshiya、Kadowaki Takashi、Kubota Naoto
- Journal Title
  
  Diabetes Research and Clinical Practice
  
  Volume: 199 Pages: 110637-110637
- DOI
  10.1016/j.diabres.2023.110637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K16347
[Journal Article] Associations of sleep quality with the skeletal muscle strength in patients with type 2 diabetes with poor glycemic control2023
- Author(s)
  Hayashi Takanori、Wada Nobuhiro、Kubota Tetsuya、Koizumi Chie、Sakurai Yoshitaka、Aihara Masakazu、Usami Satoshi、Yamauchi Toshimasa、Kubota Naoto
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 14 Issue: 6 Pages: 801-810
- DOI
  10.1111/jdi.14007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21K16347
[Journal Article] Chronic Intestinal Pseudo-obstruction with Mitochondrial Diseases2022
- Author(s)
  Jinnouchi Takanobu、Sakurai Yoshitaka、Miyoshi Kengo、Koizumi Chie、Waki Hironori、Kubota Naoto、Yamauchi Toshimasa
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 4 Pages: 469-474
- DOI
  10.2169/internalmedicine.7714-21
- NAID
  130008159809
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-02-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17977
[Journal Article] The sodium‐glucose co‐transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE‐deficient mice with streptozotocin‐induced diabetes2022
- Author(s)
  Iwamoto Masahiko、Kubota Tetsuya、Sakurai Yoshitaka、Wada Nobuhiro、Shioda Seiji、Yamauchi Toshimasa、Kadowaki Takashi、Kubota Naoto
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 10 Issue: 4
- DOI
  10.1002/prp2.971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08620, KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-20K20392, KAKENHI-PROJECT-23K24437
[Journal Article] Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone?Releasing Hormone in the Hypothalamus2021
- Author(s)
  Hayashi Takanori、Kubota Tetsuya、Mariko Inoue、Takamoto Iseki、Aihara Masakazu、Sakurai Yoshitaka、Wada Nobuhiro、Miki Takashi、Yamauchi Toshimasa、Kubota Naoto、Kadowaki Takashi
- Journal Title
  
  Diabetes
  
  Volume: 70 Issue: 8 Pages: 1640-1653
- DOI
  10.2337/db20-0482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17977, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-21K19496
[Journal Article] Role of Insulin Resistance in MAFLD2021
- Author(s)
  Sakurai Yoshitaka、Kubota Naoto、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 8 Pages: 4156-4156
- DOI
  10.3390/ijms22084156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17977
[Journal Article] Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood2020
- Author(s)
  Aihara Masakazu、Kubota Naoto、Minami Takahiro、Shirakawa Rika、Sakurai Yoshitaka、Hayashi Takanori、Iwamoto Masahiko、Takamoto Iseki、Kubota Tetsuya、Suzuki Ryo、Usami Satoshi、Jinnouchi Hideaki、Aihara Makoto、Yamauchi Toshimasa、Sakata Toshiya、Kadowaki Takashi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 2 Pages: 266-276
- DOI
  10.1111/jdi.13344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17977, KAKENHI-PROJECT-18H02860
[Journal Article] [最新論文レビュー]ハダカデバネズミは果糖を用いた解糖系により無酸素に対応できる。2018
- Author(s)
  桜井賛孝
- Journal Title
  
  DIABETES UPDATE
  
  Volume: Vol.7 No.1 Pages: 18-19
- Data Source
  KAKENHI-PROJECT-17K15612
[Journal Article] 癌におけるインスリン受容体基質の役割とPI3 キナーゼ阻害剤による癌治療。2018
- Author(s)
  桜井賛孝、窪田直人、門脇孝
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 47(4) Pages: 318-322
- NAID
  40021714319
- Data Source
  KAKENHI-PROJECT-17K15612
[Journal Article] Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney2017
- Author(s)
  Sasaki Motohiro、Sasako Takayoshi、Kubota Naoto、Sakurai Yoshitaka、Takamoto Iseki、Kubota Tetsuya、Inagi Reiko、Seki George、Goto Moritaka、Ueki Kohjiro、Nangaku Masaomi、Jomori Takahito、Kadowaki Takashi
- Journal Title
  
  Diabetes
  
  Volume: 66 Issue: 9 Pages: 2339-2350
- DOI
  10.2337/db16-1602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15612, KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465, KAKENHI-PROJECT-26000012
[Journal Article] Role of insulin receptor substrates in the progression of hepatocellular carcinoma2017
- Author(s)
  Sakurai Yoshitaka、Kubota Naoto、Takamoto Iseki、Obata Atsushi、Iwamoto Masahiko、Hayashi Takanori、Aihara Masakazu、Kubota Tetsuya、Nishihara Hiroshi、Kadowaki Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 5387-5387
- DOI
  10.1038/s41598-017-03299-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15612, KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-26000012
[Presentation] Overexpression of UBE2E2 in mouse pancreatic β-cells leads to glucose intolerance via reduction of the β-cell mass2023
- Author(s)
  桜井賛孝、窪田直人、山内敏正
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K08620
[Presentation] モデルマウスを用いた糖尿病関連遺伝子の機能解析2022
- Author(s)
  桜井賛孝、窪田直人、山内敏正
- Organizer
  第65回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08620
[Presentation] インスリンの作用異常と分泌低下がもたらす代謝異常（癌進展に及ぼす影響と分泌低下の機序）2022
- Author(s)
  桜井賛孝、窪田直人、門脇孝、山内敏正
- Organizer
  第65回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08620
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2022
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、和田亘弘、相原允一、林高則、窪田哲也、笹子敬洋、門脇孝、山内敏正
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-22K08620
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2021
- Author(s)
  桜井賛孝　窪田直人　高本偉碩　和田亘弘　林高則　窪田哲也　笹子敬洋　門脇孝　山内敏正
- Organizer
  第94回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2021
- Author(s)
  桜井賛孝　窪田直人　高本　偉碩　和田亘弘　相原允一　林高則　窪田哲也　笹子敬洋　門脇孝　山内敏正
- Organizer
  第32回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2021
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、和田亘弘、林高則、窪田哲也、笹子敬洋、門脇孝、山内敏正
- Organizer
  第41回日本肥満学会
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] インスリンの作用異常と分泌低下がもたらす代謝異常（肝癌進展に及ぼす影響と分泌低下の機序）2021
- Author(s)
  桜井賛孝　窪田直人　山内敏正
- Organizer
  第39回日本内分泌学会　内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2021
- Author(s)
  桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 林高則, 相原允一, 窪田哲也, 笹子敬洋, 門脇孝, 山内敏正
- Organizer
  第41回日本肥満学会
- Data Source
  KAKENHI-PROJECT-18K08466
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2021
- Author(s)
  桜井賛孝　窪田直人　高本偉碩　和田亘弘　相原允一　林高則　窪田哲也　笹子敬洋　門脇孝　山内敏正
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2020
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、和田亘弘、林高則、窪田哲也、笹子敬洋、門脇孝、山内敏正
- Organizer
  第93回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2020
- Author(s)
  桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 林高則, 窪田哲也, 笹子敬洋, 門脇孝, 山内敏正
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08466
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2020
- Author(s)
  桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 林高則, 窪田哲也, 笹子敬洋, 門脇孝, 山内敏正
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08466
[Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2020
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、和田亘弘、林高則、窪田哲也、笹子敬洋、門脇孝、山内敏正
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 新規糖尿病関連遺伝子UBE2E2の膵β細胞における役割2019
- Author(s)
  桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 門脇孝, 山内敏正
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08466
[Presentation] 新規糖尿病関連遺伝子UBE2E2の膵β細胞における役割2019
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、和田亘弘、門脇孝、山内敏正
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K17977
[Presentation] 新規糖尿病関連遺伝子UBE2E2の膵β細胞における役割2018
- Author(s)
  桜井賛孝, 高本偉碩, 和田亘弘, 塩田清二, 窪田直人, 門脇孝
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08466
[Presentation] 2型糖尿病感受性遺伝子KCNQ1の機能解析2018
- Author(s)
  高本偉碩, 窪田直人, 中屋恵三, 桜井賛孝, 植木浩二郎, 門脇孝
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08466
[Presentation] 肝癌におけるインスリン受容体基質(Irs)の役割2017
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、門脇孝
- Organizer
  第90回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15612
[Presentation] Role of insulin receptor substrates in the progression of hepatocellular carcinoma2017
- Author(s)
  桜井賛孝、窪田直人、高本偉碩、門脇孝
- Organizer
  第38回　日本肥満学会
- Data Source
  KAKENHI-PROJECT-17K15612

1. TAKAMOTO ISEKI (60431871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. Kubota Naoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. KUBOTA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 三木隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKURAI YOSHITAKA 桜井 賛孝

Sakurai Yoshitaka 桜井 賛孝

Research Projects

Research Products

Co-Researchers

2型糖尿病遺伝子KCNQ1の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖代謝異常の病態形成における2型糖尿病遺伝子UBE2E2の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of UBE2E2 in regulating pancreatic beta cell massPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of type 2 diabetes susceptibility genes using animal disease models

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of insulin receptor substrates in the progression of hepatocellular carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医薬のあゆみ Vol.286 No.10, 763-768.2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Bi-weekly Glycated Albumin Measurement was Useful to Encourage Behavioral Changes in People with Type 2 Diabetes Mellitus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of glycated albumin levels in tears and saliva as a marker in patients with diabetes mellitus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Associations of sleep quality with the skeletal muscle strength in patients with type 2 diabetes with poor glycemic control2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic Intestinal Pseudo-obstruction with Mitochondrial Diseases2022

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The sodium‐glucose co‐transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE‐deficient mice with streptozotocin‐induced diabetes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone?Releasing Hormone in the Hypothalamus2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Insulin Resistance in MAFLD2021

SAKURAI YOSHITAKA 桜井賛孝

Sakurai Yoshitaka 桜井賛孝

[Book] 医薬のあゆみ　Vol.286 No.10, 763-768.2023