Shinmei Shunsuke 神明俊輔

Researcher Number	70749936
Affiliation (based on the past Project Information) *help	2017 – 2020: 広島大学, 病院(医), 助教 2019: 独立行政法人国立病院機構広島西医療センター(臨床研究部), 泌尿器科, 医長 2015 – 2016: 広島大学, 病院(医), 病院助教
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Urology / Basic Section 56030:Urology-related
Keywords	Principal Investigator 癌 / 抗がん剤耐性 / 抗癌剤耐性 / 膀胱癌 / 化学療法耐性 / p38 / 尿路上皮癌 Except Principal Investigator 前立腺癌 / 去勢抵抗性前立腺癌 / 薬剤耐性 … More / 泌尿器癌 / 薬剤感受性 / オルガノイド / 再生医学 / 磁気ターゲティング / 膀胱再生 / 膀胱癌 / 抗がん剤耐性 / 抗がん剤耐性膀胱癌 Less

Establishment of personalized medicine through analysis of organoid derived from castration-resistant prostate cancer.
- Principal Investigator
  
  TEISHIMA JUN
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Hiroshima University
p38 MAPK is involved in the development of resistance to chemotherapy in urothelial carcinomaPrincipal Investigator
- Principal Investigator
  
  Shinmei Shunsuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima Nishi Medical Center
  Hiroshima University
To develop novel therapeutic targets in bladder cancer based on stemness
- Principal Investigator
  
  Hayashi Tetsutaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
To development serum Reg4 and OLFM4 as tumor markers and therapeutic targets in castration resistance prostate cancer
- Principal Investigator
  
  Matsubara Akio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
Development of urinary bladder regeneration using magnetically labeled mesenchymal stem cells with magnetic targeting system
- Principal Investigator
  
  Inoue Shogo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
Establishment of novel therapeutic strategies for castration-resistant prostate cancer by elucidation of molecular mechanism including endocrine FGFs
- Principal Investigator
  
  Teishima Jun
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University

All 2018 2017 2016

All Journal Article Presentation

[Journal Article] The effect of kinetics of C-reactive protein in the prediction of overall survival in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor.2017
- Author(s)
  Teishima J, Kobatake K, Shinmei S, Inoue S, Hayashi T, Ohara S, Mita K, Hasegawa Y, Maruyama S, Kajiwara M, Shigeta M, Mochizuki H, Moriyama H, Fujiwara S, Matsubara A.
- Journal Title
  
  Urol Oncol.
  
  Volume: Nov;35(11) Issue: 11 Pages: 662.e1-662.e7
- DOI
  10.1016/j.urolonc.2017.07.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10591
[Journal Article] Impact of neutrophil-to-lymphocyte ratio on effects of targeted therapy for metastatic renal cell carcinoma patients with extrapulmonary metastasis.2017
- Author(s)
  Teishima J, Ohara S, Sadahide K, Fujii S, Kitano H, Kobatake K, Shinmei S, Hieda K, Inoue S, Hayashi T, Mita K, Matsubara A.
- Journal Title
  
  Can Urol Assoc J.
  
  Volume: May;11(5) Issue: 5 Pages: 207-207
- DOI
  10.5489/cuaj.4106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10591
[Journal Article] Combination therapy using molecular-targeted drugs modulates tumor microenvironment and impairs tumor growth in renal cell carcinoma.2017
- Author(s)
  Kitano H, Kitadai Y, Teishima J, Yuge R, Shinmei S, Goto K, Inoue S, Hayashi T, Sentani K, Yasui W, Matsubara A.
- Journal Title
  
  Cancer Med
  
  Volume: 6 Issue: 10 Pages: 2308-2320
- DOI
  10.1002/cam4.1124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08691, KAKENHI-PROJECT-15K10591
[Journal Article] The impact of change in serum C-reactive protein level on the prediction of effects of molecular targeted therapy in patients with metastatic renal cell carcinoma.2016
- Author(s)
  Teishima J, Kobatake K, Kitano H, Nagamatsu H, Sadahide K, Hieda K, Shinmei S, Shoji K, Inoue S, Hayashi T, Inoue Y, Ohara S, Mita K, Matsubara A.
- Journal Title
  
  BJU Int.
  
  Volume: 117 Issue: 6B
- DOI
  10.1111/bju.13260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10591
[Presentation] Immunohistochemical classification using urothelial differentiation markers can stratify prognosis in patients with muscle invasive bladder cancer.2018
- Author(s)
  T. Hayashi, K. Sentani, K Goto, H.Z. Oo, H. Abdi, K. Mutaguchi, S. Shinmei, S. Inoue, J. Teishima, W. Yasui, P.C. Black, A. Matsubara.
- Organizer
  2018 AUA Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11050
[Presentation] Significance of endocrine fibroblast growth factor subfamily as serum biomarkers in castration-resistant prostate cancer.2018
- Author(s)
  Teishima J, Yamaguchi Y, Nagamatsu H, Shikuma H, Fujii S, Goto K, Shinmei S, Inoue S, Hayashi T, Matsubara A.
- Organizer
  第77回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K09134
[Presentation] The impact of endocrine fibroblast growth factor subfamily as serum biomarkers in castration-resistant prostate cancer2017
- Author(s)
  Jun Teishima, Yuka Yamaguchi, Hirotaka Nagamatsu, Shinsuke Fujii, Naoya Yabumoto, Keisuke Goto, Shunsuke Shinmei, Shogo Inoue, Tetsutaro Hayashi, Akio Matsubara
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10591
[Presentation] 転移性腎細胞癌に対するcytoreductive nephrectomy前後のCRP変動の意義.2017
- Author(s)
  亭島淳、大原慎也、神明俊輔、井上省吾、林哲太郎、望月英樹、三田耕司、松原昭郎.
- Organizer
  第3回日本泌尿器腫瘍学会
- Data Source
  KAKENHI-PROJECT-15K10591
[Presentation] STAT1 シグナルは抗がん剤耐性膀胱癌で亢進し、STAT1発現抑制が抗がん剤感受性を回復させ、新規併用治療法となる.2017
- Author(s)
  林哲太郎、郷力昭宏、神明俊輔、ピーターブラック、井上省吾、亭島淳、松原昭郎
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11006
[Presentation] 去勢抵抗性前立腺癌患者における治療前NSE値およびpro-GRP値の意義.2017
- Author(s)
  福岡憲一郎、栗村嘉昌、上野剛志、稗田景介、神明俊輔、井上省吾、林哲太郎、亭島淳、松原昭郎.
- Organizer
  第3回日本泌尿器腫瘍学会
- Data Source
  KAKENHI-PROJECT-15K10591
[Presentation] The impact of kinetics of biomarkers on the prediction of overall survival in patients with metastatic renal cell carcinoma treated with a tyrosine kinase inhibitor.2017
- Author(s)
  Jun Teishima, Shinya Ohara, Kousuke Sadahide, Shinsuke Fujii, Hiroyuki Kitano, Shunsuke Shinmei, Keisuke Hieda, Shogo Inoue, Tetsutaro Hayashi, Koji Mita, Akio Matsubara.
- Organizer
  AUA 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10591
[Presentation] STAT1 シグナルは抗がん剤耐性膀胱癌で亢進し、STAT1発現抑制が抗がん剤感受性を回復させ、新規併用治療法となる2017
- Author(s)
  林哲太郎、郷力昭宏、神明俊輔、ピーターブラック、井上省吾、亭島淳、松原昭郎
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11139
[Presentation] REGⅣは去勢抵抗性前立腺癌患者における新規のバイオマーカー候補となる.2016
- Author(s)
  藤井慎介、亭島淳、永松弘孝、正路晃一、北野弘之、後藤景介、神明俊輔、林哲太郎、大上直秀、安井弥、松原昭郎
- Organizer
  第75回日本癌学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K11007

1. Teishima Jun (20397962)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. Matsubara Akio (10239064)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
3. Inoue Shogo (90457177)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
4. Hayashi Tetsutaro (60612835)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
5. 安井弥 (40191118)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. 仲一仁 (70372688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. GORIKI akihiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. Black Peter C

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Oo Htoo Zarni

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 正路晃一 (90565805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 北野弘之 (60721933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 坂本直也 (20571798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Watt Alexander W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SENTANI Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shinmei Shunsuke 神明 俊輔

Research Projects

Research Products

Co-Researchers

Establishment of personalized medicine through analysis of organoid derived from castration-resistant prostate cancer.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

p38 MAPK is involved in the development of resistance to chemotherapy in urothelial carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To develop novel therapeutic targets in bladder cancer based on stemness

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To development serum Reg4 and OLFM4 as tumor markers and therapeutic targets in castration resistance prostate cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of urinary bladder regeneration using magnetically labeled mesenchymal stem cells with magnetic targeting system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of novel therapeutic strategies for castration-resistant prostate cancer by elucidation of molecular mechanism including endocrine FGFs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The effect of kinetics of C-reactive protein in the prediction of overall survival in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of neutrophil-to-lymphocyte ratio on effects of targeted therapy for metastatic renal cell carcinoma patients with extrapulmonary metastasis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination therapy using molecular-targeted drugs modulates tumor microenvironment and impairs tumor growth in renal cell carcinoma.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The impact of change in serum C-reactive protein level on the prediction of effects of molecular targeted therapy in patients with metastatic renal cell carcinoma.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Immunohistochemical classification using urothelial differentiation markers can stratify prognosis in patients with muscle invasive bladder cancer.2018

Author(s)

Organizer

Data Source

[Presentation] Significance of endocrine fibroblast growth factor subfamily as serum biomarkers in castration-resistant prostate cancer.2018

Author(s)

Organizer

Data Source

[Presentation] The impact of endocrine fibroblast growth factor subfamily as serum biomarkers in castration-resistant prostate cancer2017

Author(s)

Organizer

Data Source

[Presentation] 転移性腎細胞癌に対するcytoreductive nephrectomy前後のCRP変動の意義.2017

Author(s)

Organizer

Data Source

[Presentation] STAT1 シグナルは抗がん剤耐性膀胱癌で亢進し、STAT1発現抑制が抗がん剤感受性を回復させ、新規併用治療法となる.2017

Author(s)

Organizer

Data Source

Shinmei Shunsuke 神明俊輔