Asada Rie 浅田梨絵

Researcher Number	70751882
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2019: 広島大学, 医系科学研究科(医), 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(医), 助教 2015 – 2016: 広島大学, 医歯薬保健学研究院(医), 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / General medical chemistry / Metabolomics
Keywords	Principal Investigator 糖尿病 / 小胞体ストレス / 核膜 / DNA損傷 / 小胞体 / 細胞老化 / XBP1 / IRE1α / UCP1 / 褐色脂肪細胞 / 小胞体ストレス応答

MANF利用による小胞体ストレスを標的としたⅠ型糖尿病治療法開発の基盤構築Principal Investigator
- Principal Investigator
  
  浅田梨絵
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
The role of ER-resident transmembrane protein OASIS in cellular senescencePrincipal Investigator
- Principal Investigator
  
  Asada Rie
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
The role of unfolded protein response in brown adipocytesPrincipal Investigator
- Principal Investigator
  
  Asada Rie
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University

All 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells.2019
- Author(s)
  Maeoka Y, Wu Y, Okamoto T, Kanemoto S, Guo XP, Saito A, Asada R, Matsuhisa K, Masaki T, Imaizumi K, Kaneko M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Issue: 1 Pages: 101-115
- DOI
  10.1074/jbc.ra118.002896
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10052, KAKENHI-PROJECT-18K06685, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06416, KAKENHI-PROJECT-17H01424, KAKENHI-PROJECT-18H06105, KAKENHI-PROJECT-17K15599
[Journal Article] Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.2018
- Author(s)
  Osaki Y, Saito A, Kanemoto S, Kaneko M, Matsuhisa K, Asada R, Masaki T, Orii K, Fukao T, Tomatsu S, Imaizumi K
- Journal Title
  
  Cell Death Dis.
  
  Volume: 9 Issue: 8 Pages: 808-808
- DOI
  10.1038/s41419-018-0871-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10052, KAKENHI-PROJECT-18K06685, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06416, KAKENHI-PROJECT-17H01424, KAKENHI-PROJECT-17K15599
[Journal Article] Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury.2018
- Author(s)
  Ohtake Y, Matsuhisa K, Kaneko M, Kanemoto S, Asada R, Imaizumi K, Saito A.
- Journal Title
  
  Neuroscience
  
  Volume: 375 Pages: 34-48
- DOI
  10.1016/j.neuroscience.2018.02.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10052, KAKENHI-PROJECT-17K15599, KAKENHI-PLANNED-17H06416, KAKENHI-PROJECT-17H06891, KAKENHI-PROJECT-18K06685, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01424
[Journal Article] Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma.2018
- Author(s)
  Saito A, Cai L, Matsuhisa K, Ohtake Y, Kaneko M, Kanemoto S, Asada R, Imaizumi K.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 144 Issue: 1 Pages: 35-49
- DOI
  10.1111/jnc.14221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10052, KAKENHI-PROJECT-17K15599, KAKENHI-PLANNED-17H06416, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01424
[Journal Article] Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183.2018
- Author(s)
  Wu Y, Guo XP, Kanemoto S, Maeoka Y, Saito A, Asada R, Matsuhisa K, Ohtake Y, Imaizumi K, Kaneko M.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 1 Pages: e0190407-e0190407
- DOI
  10.1371/journal.pone.0190407
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10052, KAKENHI-PROJECT-17K15599, KAKENHI-PLANNED-17H06416, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01424
[Journal Article] ER Stress and Disease: Toward Prevention and Treatment2017
- Author(s)
  Kaneko M, Imaizumi K, Saito A, Kanemoto S, Asada R, Matsuhisa K, Ohtake Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 9 Pages: 1337-1343
- DOI
  10.1248/bpb.b17-00342
- NAID
  130006038767
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10052, KAKENHI-PROJECT-17K15599
[Journal Article] The androgen-induced protein AIbZIP facilitates proliferation of prostate cancer cells through downregulation of p21 expression2016
- Author(s)
  Cui X, Cui M, Asada R, Kanemoto S, Saito A, Matsuhisa K, Kaneko M, Imaizumi K
- Journal Title
  
  Scientific reports
  
  Volume: 6 Issue: 1 Pages: 37310-37310
- DOI
  10.1038/srep37310
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21706, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001
[Journal Article] Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress2016
- Author(s)
  Kanemoto S, Nitani R, Murakami T, Kaneko M, Asada R, Matsuhisa K, Saito A, Imaizumi K
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 480 Issue: 2 Pages: 166-172
- DOI
  10.1016/j.bbrc.2016.10.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21706, KAKENHI-PROJECT-15K15067, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001
[Journal Article] Promotion of cancer cell proliferation by cleaved and secreted luminal domains of ER stress transducer BBF2H7.2015
- Author(s)
  Iwamoto H, Matsuhisa K, Saito A, Kanemoto S, Asada R, Hino K, Takai T, Cui M, Cui X, Kaneko M, Arihiro K, Sugiyama K, Kurisu K, Matsubara A, Imaizumi K.
- Journal Title
  
  Plos One
  
  Volume: 10 Issue: 5 Pages: 1-17
- DOI
  10.1371/journal.pone.0125982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659678, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-15K18377
[Journal Article] Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.2015
- Author(s)
  Kanemoto S, Kobayashi Y, Yamashita T, Miyamoto T, Cui M, Asada R, Cui X, Hino K, Kaneko M, Takai T, Matsuhisa K, Takahashi N, Imaizumi K.
- Journal Title
  
  J Cell Sci
  
  Volume: 128 Pages: 4353-4365
- DOI
  10.1242/jcs.176057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-15K18377, KAKENHI-PROJECT-15K21706
[Journal Article] IRE1a-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes.2015
- Author(s)
  Asada R, Kanemoto S, Matsuhisa K, Hino K, Cui M, Cui X, Kaneko M, Imaizumi K.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16580-16580
- DOI
  10.1038/srep16580
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15067, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-15K21706
[Journal Article] OASIS modulates hypoxia pathway activity to regulate bone angiogenesis.2015
- Author(s)
  Min Cui, Soshi Kanemoto, Xiang Cui, Masayuki Kaneko, Rie Asada, Koji Matsuhisa, Keiji Tanimoto, Yuki Yoshimoto, Chisa Shukunami, Kazunori Imaizumi.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16455-16455
- DOI
  10.1038/srep16455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-26293395, KAKENHI-PROJECT-15K21706
[Presentation] 小胞体局在膜貫通型転写因子OASISの核ブレブ集積機構2019
- Author(s)
  松久幸司、浅田梨絵、金子雅幸、今泉和則
- Organizer
  新学術領域「オルガネラ・ゾーン」第1回若手の会
- Data Source
  KAKENHI-PROJECT-17K15599
[Presentation] アストロサイトの核膜ストレスを制御する小胞体膜タンパク質2019
- Author(s)
  松久幸司、金子雅幸、齋藤敦、浅田梨絵、今泉和則
- Organizer
  『広島神経医科学研究会』第3回学生・若手研究者のポスター発表会
- Data Source
  KAKENHI-PROJECT-17K15599
[Presentation] DNA品質管理を担う核－小胞体連携ゾーンの解析2018
- Author(s)
  今泉和則、松久幸司、浅田梨絵、金子雅幸
- Organizer
  第1回新学術領域「オルガネラ・ゾーン」全体班会議
- Data Source
  KAKENHI-PROJECT-17K15599
[Presentation] ER-resident transmembrane transcription factor OASIS accumulates in the nuclear bleb in response to the disruption of the nuclear lamina2018
- Author(s)
  Matsuhisa K, Asada R, Kaneko M, Imaizumi K.
- Organizer
  ASCB | EMBO 2018 Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15599
[Presentation] 小胞体ストレストランスデューサーOASISの核膜blebにおける特徴的な局在と機能について2018
- Author(s)
  松久幸司、浅田梨絵、金子雅幸、今泉和則
- Organizer
  第19回ORIGIN神経科学研究会2018
- Data Source
  KAKENHI-PROJECT-17K15599
[Presentation] 小胞体膜タンパク質OASISの核膜への局所的集積とその生理的意義2017
- Author(s)
  浅田梨絵、金子雅幸、今泉和則
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K15599
[Presentation] ER-resident transmembrane transcription factor OASIS plays important role in DNA damage response2016
- Author(s)
  Asada R, Kikushima K, Cui M, Imaizumi K
- Organizer
  ASCB Annual Meeting
- Place of Presentation
  サンフランシスコ, 米国
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19516
[Presentation] アストロサイトの細胞分化における小胞体膜貫通型転写因子OASISの働き2016
- Author(s)
  浅田梨絵、崔旻、今泉和則
- Organizer
  第59回日本神経化学会大会
- Place of Presentation
  福岡市
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K19516
[Presentation] IRE1α-XBP1経路による褐色脂肪細胞の熱産生遺伝子Ucp1の発現制御2015
- Author(s)
  浅田梨絵、今泉和則
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K19516
[Presentation] 小胞体ストレス応答による褐色脂肪細胞の機能調節2015
- Author(s)
  浅田梨絵、今泉和則
- Organizer
  第56回日本生化学会・中国・四国支部例会
- Place of Presentation
  島根大学（島根県松江市）
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K19516
[Presentation] 褐色脂肪細胞における小胞体ストレス応答の役割2015
- Author(s)
  浅田梨絵、今泉和則
- Organizer
  第10回小胞体ストレス研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K19516

1. SAITO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 山下照仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 金子雅幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 金本聡自

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
5. 今泉和則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 谷本圭司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Asada Rie 浅田 梨絵

Research Projects

Research Products

Co-Researchers

MANF利用による小胞体ストレスを標的としたⅠ型糖尿病治療法開発の基盤構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of ER-resident transmembrane protein OASIS in cellular senescencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of unfolded protein response in brown adipocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ER Stress and Disease: Toward Prevention and Treatment2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] The androgen-induced protein AIbZIP facilitates proliferation of prostate cancer cells through downregulation of p21 expression2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Promotion of cancer cell proliferation by cleaved and secreted luminal domains of ER stress transducer BBF2H7.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IRE1a-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes.2015

Author(s)

Journal Title

DOI

Data Source

Asada Rie 浅田梨絵