Ono Hitomi 皆木瞳

… Alternative Names

Minagi Hitomi 皆木瞳

小野瞳オノヒトミ

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Researcher Number	70754810
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院歯学研究科, 招へい教員
Affiliation (based on the past Project Information) *help	2025: 岡山大学, 医歯薬学総合研究科, 特別研究員(RPD) 2020 – 2023: 岡山大学, 医歯薬学総合研究科, 特別研究員(RPD) 2020: 岡山大学, 大学院医歯薬学総合研究科, 特別研究員(RPD) 2019: 大阪大学, 歯学研究科, 特別研究員(RPD) 2016 – 2018: 大阪大学, 歯学研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 再生 / 唾液腺 / 発生 / シェーグレン症候群 / 口腔乾燥症 / 組織再生 / ピロカルピン塩酸塩 / 顎下腺 / 再生医療 Except Principal Investigator 臓器再生 / 唾液腺

オミクス解析から紐解くシェーグレン症候群の疾患多様性解明Principal Investigator
- Principal Investigator
  
  皆木瞳
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
An Attempt at Functional Salivary Gland Regeneration Based on the Origin of the Salivary GlandPrincipal Investigator
- Principal Investigator
  
  Minagi Hitomi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
Japan/US collaboration research for organ regeneration reusing unused FDA-approved drug
- Principal Investigator
  
  阪井丘芳
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
シェーグレン症候群の発症メカニズムの解明-Runx1との関与-Principal Investigator
- Principal Investigator
  
  皆木瞳
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
  Osaka University
Differences between regenerating salivary glands after salivary gland duct ligation and embryonic salivary glandsPrincipal Investigator
- Principal Investigator
  
  Minagi Hitomi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
  Osaka University
The elucidation of stem cell in salivary gland reproduction by using drugPrincipal Investigator
- Principal Investigator
  
  Minagi Hitomi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 歯界展望2023
- Author(s)
  皆木瞳 , 上原史帆 , 福井美恵 , 伍賀浩子 , 阪井丘芳
- Total Pages
  5
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-21K10093
[Journal Article] Evaluation of oral care using MA-T gel for high-risk patients: a pilot study.2023
- Author(s)
  Ono-Minagi H, Gojo N, Nohno T, Inoue T, Ohuchi H, Sakai T.
- Journal Title
  
  BMC Oral Health.
  
  Volume: 23(1) Issue: 1 Pages: 108-108
- DOI
  10.1186/s12903-023-02779-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2303, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-21K10093
[Journal Article] Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia2023
- Author(s)
  Kano Fumiya、Hashimoto Noboru、Liu Yao、Xia Linze、Nishihara Takaaki、Oki Wakana、Kawarabayashi Keita、Mizusawa Noriko、Aota Keiko、Sakai Takayoshi、Azuma Masayuki、Hibi Hideharu、Iwasaki Tomonori、Iwamoto Tsutomu、Horimai Nobuyasu、Yamamoto Akihito
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 2706-2706
- DOI
  10.1038/s41598-023-29176-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03055, KAKENHI-PROJECT-19K18241, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19H03851
[Journal Article] The Germinal Origin of Salivary and Lacrimal Glands and the Contributions of Neural Crest Cell-Derived Epithelium to Tissue Regeneration2023
- Author(s)
  Ono-Minagi Hitomi、Nohno Tsutomu、Serizawa Takashi、Usami Yu、Sakai Takayoshi、Okano Hideyuki、Ohuchi Hideyo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 18 Pages: 13692-13692
- DOI
  10.3390/ijms241813692
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2303, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-21K10093, KAKENHI-PROJECT-20K21655
[Journal Article] Analysis of medication-induced xerostomia in elderly Japanese patients2021
- Author(s)
  Minagi Hitomi Ono、Yamanaka Yoshie、Nohara Kanji、Ikai Kazuki、Sakai Takayoshi
- Journal Title
  
  Clinical Oral Investigations
  
  Volume: 26 Issue: 2 Pages: 2021-2029
- DOI
  10.1007/s00784-021-04182-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-21K10093, KAKENHI-PROJECT-21K10251, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-22KJ2303, KAKENHI-PROJECT-19H03852
[Journal Article] Morphological differences between regenerating salivary glands after salivary gland duct ligation and embryonic salivary glands2020
- Author(s)
  Ono Minagi Hitomi、Usami Yu、Sakai Manabu、Sakai Takayoshi
- Journal Title
  
  Annals of Anatomy - Anatomischer Anzeiger
  
  Volume: 229 Pages: 151482-151482
- DOI
  10.1016/j.aanat.2020.151482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-19H03852
[Journal Article] Effect of xanthan gum-thickened liquid aspiration on the lungs in a mouse model2020
- Author(s)
  Araie T, Ono Minagi H, Usami Y, Ikai K, Sakai M, Gojo N, Nohara K, Sakai T.
- Journal Title
  
  Oral Sci Int
  
  Volume: 1 Pages: 1348-8643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J40027
[Journal Article] Evaluation of the Saxon test for patients with hyposalivation without Sj?gren’s syndrome2020
- Author(s)
  Ono Minagi Hitomi、Yamanaka Yoshie、Sakai Takayoshi
- Journal Title
  
  Journal of Oral Rehabilitation
  
  Volume: 47 Issue: 12 Pages: 1550-1556
- DOI
  10.1111/joor.13093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19H03852, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-22KJ2303
[Journal Article] ΔNp63 is upregulated during salivary gland regeneration following duct ligation and irradiation in mice2020
- Author(s)
  Ikai Kazuki、Sakai Manabu、Minagi Hitomi Ono、Gojo Nao、Sakai Takayoshi
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 19 Pages: 3216-3226
- DOI
  10.1002/1873-3468.13896
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19K19155, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19K24070, KAKENHI-PROJECT-19H03852
[Journal Article] Anterior cleft palate due to Cbfb deficiency and its rescue by folic acid2019
- Author(s)
  Sarper Safiye E.、Inubushi Toshihiro、Kurosaka Hiroshi、Ono Minagi Hitomi、Murata Yuka、Kuremoto Koh-ichi、Sakai Takayoshi、Taniuchi Ichiro、Yamashiro Takashi
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 12 Issue: 6 Pages: 038851-038851
- DOI
  10.1242/dmm.038851
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19KK0230, KAKENHI-PLANNED-19H05747, KAKENHI-PROJECT-17H04090, KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-18K19645
[Journal Article] Role of the mTOR signalling pathway in salivary gland development2019
- Author(s)
  Sakai Manabu、Fukumoto Moe、Ikai Kazuki、Ono Minagi Hitomi、Inagaki Shinobu、Kogo Mikihiko、Sakai Takayoshi
- Journal Title
  
  The FEBS Journal
  
  Volume: 286 Issue: 18 Pages: 3701-3717
- DOI
  10.1111/febs.14937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19K19155, KAKENHI-PROJECT-19KK0230
[Journal Article] Benefits of long-term pilocarpine due to increased muscarinic acetylcholine receptor 3 in salivary glands.2018
- Author(s)
  Minagi HO, Ikai K, Araie T, Sakai M, Sakai T
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 503 Issue: 2 Pages: 1098-1102
- DOI
  10.1016/j.bbrc.2018.06.125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15737, KAKENHI-PROJECT-16K20573, KAKENHI-PROJECT-17K17244, KAKENHI-PROJECT-15H02575, KAKENHI-PROJECT-18K17223
[Journal Article] Runx1 mediates the development of the granular convoluted tubules in the submandibular glands2017
- Author(s)
  Ono Minagi Hitomi、Sarper Safiye Esra、Kurosaka Hiroshi、Kuremoto Koh-ichi、Taniuchi Ichiro、Sakai Takayoshi、Yamashiro Takashi
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 9 Pages: 0184395-0184395
- DOI
  10.1371/journal.pone.0184395
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11592, KAKENHI-PROJECT-16K15836, KAKENHI-PUBLICLY-17H05805, KAKENHI-PROJECT-15H02577, KAKENHI-PROJECT-15H05687, KAKENHI-PROJECT-16K20573
[Presentation] The embryonic origins of exocrine Glands and the role neural crest-derived epithelium in tissue regeneration.2024
- Author(s)
  Hitomi Minagi, Tsutomu Nohno, Takashi Serizawa, Yu Usami, Takayoshi Sakai, Hideyuki Okano, John A Chiorini and Hideyo Ohuchi
- Organizer
  International Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 病棟との連携により歯科訪問診療での非経口摂取高齢者の口腔内環境が改善した３症例2023
- Author(s)
  皆木瞳
- Organizer
  老年歯科医学会
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 院内感染予防のための MA - T 含有口腔ケアジェルの社会実装2023
- Author(s)
  皆木瞳、五條菜央、濃野勉、大内淑代、阪井丘芳
- Organizer
  MA-T学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] Predictor of Sjogren’s syndrome severity by spatial analysis of labial glands2023
- Author(s)
  Hitomi Ono-Minagi, Tsutomu Nohno, Takayoshi Sakai, Hideyo Ohuchi
- Organizer
  Gordon research conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 口唇腺の Spatial 解析によるシェーグレン症候群の予後予測因子解明2023
- Author(s)
  皆木瞳、高畠清文、伊原木聰一郎、飯田征二、長塚仁、阪井丘芳、大内淑代
- Organizer
  日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 口腔乾燥症の層別化に基づく新たな治療戦略2022
- Author(s)
  皆木　瞳
- Organizer
  日本唾液腺学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 唾液腺組織の再生過程は発生過程を模倣しているか？2021
- Author(s)
  皆木　瞳、宇佐美悠、酒井学、井階一樹、大内　淑代、阪井　丘芳
- Organizer
  日本口腔科学会
- Data Source
  KAKENHI-PROJECT-18K17223
[Presentation] 高齢者の服薬と口腔乾燥症の実態解明-治療法の確立を目指して-2021
- Author(s)
  皆木瞳、山中賀惠、野原幹司、大内淑代、阪井丘芳
- Organizer
  日本唾液腺学会
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 高齢者の服薬と口腔乾燥症の実態解明-治療法の確立を目指して-2021
- Author(s)
  皆木瞳、山中賀惠、野原幹司、大内淑代、阪井丘芳
- Organizer
  日本唾液腺学会
- Data Source
  KAKENHI-PROJECT-19J40027
[Presentation] サクソンテストはすべての患者で有効か -非シェーグレン症候群患者における調査-2021
- Author(s)
  皆木　瞳、山中惠賀、大内淑代、阪井丘芳
- Organizer
  日本老年歯科医学会
- Data Source
  KAKENHI-PROJECT-18K17223
[Presentation] 高齢者の服薬と口腔乾燥症の実態解明-治療法の確立を目指して-2021
- Author(s)
  皆木瞳、山中賀惠、野原幹司、大内淑代、阪井丘芳
- Organizer
  日本唾液腺学会
- Data Source
  KAKENHI-PROJECT-18K17223
[Presentation] サクソンテストはすべての患者で有効か -非シェーグレン症候群患者における調査-2021
- Author(s)
  皆木　瞳、山中惠賀、大内淑代、阪井丘芳
- Organizer
  日本老年歯科医学会
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 非シェーグレン症候群患者におけるサクソンテストの有効性の検討2021
- Author(s)
  皆木　瞳、大内　淑代、阪井　丘芳
- Organizer
  日本口腔科学会
- Data Source
  KAKENHI-PROJECT-18K17223
[Presentation] 唾液腺組織の再生過程は発生過程を模倣しているか？2021
- Author(s)
  皆木　瞳、宇佐美悠、酒井学、井階一樹、大内　淑代、阪井　丘芳
- Organizer
  日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] サクソンテストはすべての患者で有効か -非シェーグレン症候群患者における調査-2021
- Author(s)
  皆木　瞳、山中惠賀、大内淑代、阪井丘芳
- Organizer
  日本老年歯科医学会
- Data Source
  KAKENHI-PROJECT-19J40027
[Presentation] 非シェーグレン症候群患者におけるサクソンテストの有効性の検討2021
- Author(s)
  皆木　瞳、大内　淑代、阪井　丘芳
- Organizer
  日本口腔科学会
- Data Source
  KAKENHI-PROJECT-21K10093
[Presentation] 唾液腺障害モデルから探索する再生医療への可能性2020
- Author(s)
  皆木瞳
- Organizer
  歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19J40027
[Presentation] 発生過程の解明に基づく唾液腺再生への可能性2020
- Author(s)
  皆木　瞳, 宇佐美　悠, 酒井　学, 大内　淑代, 阪井　丘芳
- Organizer
  日本歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K17223
[Presentation] 唾液腺障害モデルから探索する再生医療への可能性2019
- Author(s)
  皆木瞳
- Organizer
  歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19J40027
[Presentation] 唾液腺障害モデルから探索する再生医療への可能性2019
- Author(s)
  皆木　瞳, 宇佐美　悠, 井階　一樹, 阪井　丘芳
- Organizer
  日本歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K17223
[Presentation] 唾液腺性差とRunx1cKOマウスの唾液分泌制御機構2017
- Author(s)
  皆木瞳
- Organizer
  歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-16K20573
[Presentation] Pilocarpine benefit in stem cell therapy2017
- Author(s)
  Ono Hitomi
- Organizer
  Gordon research conference
- Place of Presentation
  Texas, U.S.A
- Year and Date
  2017-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20573
[Presentation] 口腔乾燥症状に対するピロカルピンの継続的服用の有効性2016
- Author(s)
  小野　瞳
- Organizer
  日本基礎歯科医学界
- Place of Presentation
  札幌コンベンションセンター、札幌、北海道
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K20573

1. 阪井丘芳 (90379082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 井階一樹 (00849432)

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3. 田中信和 (20570295)

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4. 山本朗仁

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# of Collaborated Products: 1 results
5. 橋本登

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6. 加納史也

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7. 呉本晃一

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Ono Hitomi 皆木 瞳

Minagi Hitomi 皆木 瞳

小野 瞳 オノ ヒトミ

Research Projects

Research Products

Co-Researchers

オミクス解析から紐解くシェーグレン症候群の疾患多様性解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An Attempt at Functional Salivary Gland Regeneration Based on the Origin of the Salivary GlandPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Japan/US collaboration research for organ regeneration reusing unused FDA-approved drug

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シェーグレン症候群の発症メカニズムの解明-Runx1との関与-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Differences between regenerating salivary glands after salivary gland duct ligation and embryonic salivary glandsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of stem cell in salivary gland reproduction by using drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 歯界展望2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Evaluation of oral care using MA-T gel for high-risk patients: a pilot study.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Germinal Origin of Salivary and Lacrimal Glands and the Contributions of Neural Crest Cell-Derived Epithelium to Tissue Regeneration2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of medication-induced xerostomia in elderly Japanese patients2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Morphological differences between regenerating salivary glands after salivary gland duct ligation and embryonic salivary glands2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of xanthan gum-thickened liquid aspiration on the lungs in a mouse model2020

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of the Saxon test for patients with hyposalivation without Sj?gren’s syndrome2020

Author(s)

Journal Title

DOI

Ono Hitomi 皆木瞳

Minagi Hitomi 皆木瞳

小野瞳オノヒトミ

[Presentation] 病棟との連携により歯科訪問診療での非経口摂取高齢者の口腔内環境が改善した３症例2023