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Ono Hitomi  皆木 瞳

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… Alternative Names

Minagi Hitomi  皆木 瞳

小野 瞳  オノ ヒトミ

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Researcher Number 70754810
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院歯学研究科, 招へい教員
Affiliation (based on the past Project Information) *help 2025: 岡山大学, 医歯薬学総合研究科, 特別研究員(RPD)
2020 – 2023: 岡山大学, 医歯薬学総合研究科, 特別研究員(RPD)
2020: 岡山大学, 大学院医歯薬学総合研究科, 特別研究員(RPD)
2019: 大阪大学, 歯学研究科, 特別研究員(RPD)
2016 – 2018: 大阪大学, 歯学研究科, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Except Principal Investigator
Medium-sized Section 57:Oral science and related fields
Keywords
Principal Investigator
再生 / 唾液腺 / 発生 / シェーグレン症候群 / 口腔乾燥症 / 組織再生 / ピロカルピン塩酸塩 / 顎下腺 / 再生医療
Except Principal Investigator
臓器再生 / 唾液腺
  • Research Projects

    (6 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (7 People)
  •  オミクス解析から紐解くシェーグレン症候群の疾患多様性解明Principal Investigator

    • Principal Investigator
      皆木 瞳
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Okayama University
  •  An Attempt at Functional Salivary Gland Regeneration Based on the Origin of the Salivary GlandPrincipal Investigator

    • Principal Investigator
      Minagi Hitomi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Okayama University
  •  Japan/US collaboration research for organ regeneration reusing unused FDA-approved drug

    • Principal Investigator
      阪井 丘芳
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Osaka University
  •  シェーグレン症候群の発症メカニズムの解明-Runx1との関与-Principal Investigator

    • Principal Investigator
      皆木 瞳
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Okayama University
      Osaka University
  •  Differences between regenerating salivary glands after salivary gland duct ligation and embryonic salivary glandsPrincipal Investigator

    • Principal Investigator
      Minagi Hitomi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Okayama University
      Osaka University
  •  The elucidation of stem cell in salivary gland reproduction by using drugPrincipal Investigator

    • Principal Investigator
      Minagi Hitomi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

  • [Book] 歯界展望2023

    • Author(s)
      皆木 瞳 , 上原 史帆 , 福井 美恵 , 伍賀 浩子 , 阪井 丘芳
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Journal Article] Evaluation of oral care using MA-T gel for high-risk patients: a pilot study.2023

    • Author(s)
      Ono-Minagi H, Gojo N, Nohno T, Inoue T, Ohuchi H, Sakai T.
    • Journal Title

      BMC Oral Health.

      Volume: 23(1) Issue: 1 Pages: 108-108

    • DOI

      10.1186/s12903-023-02779-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ2303, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-21K10093
  • [Journal Article] Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia2023

    • Author(s)
      Kano Fumiya、Hashimoto Noboru、Liu Yao、Xia Linze、Nishihara Takaaki、Oki Wakana、Kawarabayashi Keita、Mizusawa Noriko、Aota Keiko、Sakai Takayoshi、Azuma Masayuki、Hibi Hideharu、Iwasaki Tomonori、Iwamoto Tsutomu、Horimai Nobuyasu、Yamamoto Akihito
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 2706-2706

    • DOI

      10.1038/s41598-023-29176-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03055, KAKENHI-PROJECT-19K18241, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19H03851
  • [Journal Article] The Germinal Origin of Salivary and Lacrimal Glands and the Contributions of Neural Crest Cell-Derived Epithelium to Tissue Regeneration2023

    • Author(s)
      Ono-Minagi Hitomi、Nohno Tsutomu、Serizawa Takashi、Usami Yu、Sakai Takayoshi、Okano Hideyuki、Ohuchi Hideyo
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 18 Pages: 13692-13692

    • DOI

      10.3390/ijms241813692

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ2303, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-21K10093, KAKENHI-PROJECT-20K21655
  • [Journal Article] Analysis of medication-induced xerostomia in elderly Japanese patients2021

    • Author(s)
      Minagi Hitomi Ono、Yamanaka Yoshie、Nohara Kanji、Ikai Kazuki、Sakai Takayoshi
    • Journal Title

      Clinical Oral Investigations

      Volume: 26 Issue: 2 Pages: 2021-2029

    • DOI

      10.1007/s00784-021-04182-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-21K10093, KAKENHI-PROJECT-21K10251, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-22KJ2303, KAKENHI-PROJECT-19H03852
  • [Journal Article] Morphological differences between regenerating salivary glands after salivary gland duct ligation and embryonic salivary glands2020

    • Author(s)
      Ono Minagi Hitomi、Usami Yu、Sakai Manabu、Sakai Takayoshi
    • Journal Title

      Annals of Anatomy - Anatomischer Anzeiger

      Volume: 229 Pages: 151482-151482

    • DOI

      10.1016/j.aanat.2020.151482

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-19H03852
  • [Journal Article] Effect of xanthan gum-thickened liquid aspiration on the lungs in a mouse model2020

    • Author(s)
      Araie T, Ono Minagi H, Usami Y, Ikai K, Sakai M, Gojo N, Nohara K, Sakai T.
    • Journal Title

      Oral Sci Int

      Volume: 1 Pages: 1348-8643

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19J40027
  • [Journal Article] Evaluation of the Saxon test for patients with hyposalivation without Sj?gren’s syndrome2020

    • Author(s)
      Ono Minagi Hitomi、Yamanaka Yoshie、Sakai Takayoshi
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 12 Pages: 1550-1556

    • DOI

      10.1111/joor.13093

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19H03852, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-22KJ2303
  • [Journal Article] ΔNp63 is upregulated during salivary gland regeneration following duct ligation and irradiation in mice2020

    • Author(s)
      Ikai Kazuki、Sakai Manabu、Minagi Hitomi Ono、Gojo Nao、Sakai Takayoshi
    • Journal Title

      FEBS Letters

      Volume: 594 Issue: 19 Pages: 3216-3226

    • DOI

      10.1002/1873-3468.13896

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19K19155, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19K24070, KAKENHI-PROJECT-19H03852
  • [Journal Article] Anterior cleft palate due to Cbfb deficiency and its rescue by folic acid2019

    • Author(s)
      Sarper Safiye E.、Inubushi Toshihiro、Kurosaka Hiroshi、Ono Minagi Hitomi、Murata Yuka、Kuremoto Koh-ichi、Sakai Takayoshi、Taniuchi Ichiro、Yamashiro Takashi
    • Journal Title

      Disease Models & Mechanisms

      Volume: 12 Issue: 6 Pages: 038851-038851

    • DOI

      10.1242/dmm.038851

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19KK0230, KAKENHI-PLANNED-19H05747, KAKENHI-PROJECT-17H04090, KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-19J40027, KAKENHI-PROJECT-18K19645
  • [Journal Article] Role of the mTOR signalling pathway in salivary gland development2019

    • Author(s)
      Sakai Manabu、Fukumoto Moe、Ikai Kazuki、Ono Minagi Hitomi、Inagaki Shinobu、Kogo Mikihiko、Sakai Takayoshi
    • Journal Title

      The FEBS Journal

      Volume: 286 Issue: 18 Pages: 3701-3717

    • DOI

      10.1111/febs.14937

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K17223, KAKENHI-PROJECT-19K19155, KAKENHI-PROJECT-19KK0230
  • [Journal Article] Benefits of long-term pilocarpine due to increased muscarinic acetylcholine receptor 3 in salivary glands.2018

    • Author(s)
      Minagi HO, Ikai K, Araie T, Sakai M, Sakai T
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 503 Issue: 2 Pages: 1098-1102

    • DOI

      10.1016/j.bbrc.2018.06.125

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15737, KAKENHI-PROJECT-16K20573, KAKENHI-PROJECT-17K17244, KAKENHI-PROJECT-15H02575, KAKENHI-PROJECT-18K17223
  • [Journal Article] Runx1 mediates the development of the granular convoluted tubules in the submandibular glands2017

    • Author(s)
      Ono Minagi Hitomi、Sarper Safiye Esra、Kurosaka Hiroshi、Kuremoto Koh-ichi、Taniuchi Ichiro、Sakai Takayoshi、Yamashiro Takashi
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 9 Pages: 0184395-0184395

    • DOI

      10.1371/journal.pone.0184395

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11592, KAKENHI-PROJECT-16K15836, KAKENHI-PUBLICLY-17H05805, KAKENHI-PROJECT-15H02577, KAKENHI-PROJECT-15H05687, KAKENHI-PROJECT-16K20573
  • [Presentation] The embryonic origins of exocrine Glands and the role neural crest-derived epithelium in tissue regeneration.2024

    • Author(s)
      Hitomi Minagi, Tsutomu Nohno, Takashi Serizawa, Yu Usami, Takayoshi Sakai, Hideyuki Okano, John A Chiorini and Hideyo Ohuchi
    • Organizer
      International Association for Dental Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 病棟との連携により歯科訪問診療での非経口摂取高齢者の 口腔内環境が改善した3症例2023

    • Author(s)
      皆木瞳
    • Organizer
      老年歯科医学会
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 院内感染予防のための MA - T 含有口腔ケアジェルの社会実装2023

    • Author(s)
      皆木 瞳、五條 菜央、濃野 勉 、大内 淑代、阪井 丘芳
    • Organizer
      MA-T学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] Predictor of Sjogren’s syndrome severity by spatial analysis of labial glands2023

    • Author(s)
      Hitomi Ono-Minagi, Tsutomu Nohno, Takayoshi Sakai, Hideyo Ohuchi
    • Organizer
      Gordon research conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 口唇腺の Spatial 解析によるシェーグレン症候群の予後予測因子解明2023

    • Author(s)
      皆木 瞳 、高畠清文 、伊原木聰一郎 、飯田征二 、 長塚 仁 、阪井丘芳 、大内淑代
    • Organizer
      日本口腔科学会
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 口腔乾燥症の層別化に基づく新たな治療戦略2022

    • Author(s)
      皆木 瞳
    • Organizer
      日本唾液腺学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 唾液腺組織の再生過程は発生過程を模倣しているか?2021

    • Author(s)
      皆木 瞳、宇佐美 悠、酒井 学、井階一樹、大内 淑代、阪井 丘芳
    • Organizer
      日本口腔科学会
    • Data Source
      KAKENHI-PROJECT-18K17223
  • [Presentation] 高齢者の服薬と口腔乾燥症の実態解明-治療法の確立を目指して-2021

    • Author(s)
      皆木 瞳、山中 賀惠、野原 幹司、大内 淑代、阪井 丘芳
    • Organizer
      日本唾液腺学会
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 高齢者の服薬と口腔乾燥症の実態解明-治療法の確立を目指して-2021

    • Author(s)
      皆木 瞳、山中 賀惠、野原 幹司、大内 淑代、阪井 丘芳
    • Organizer
      日本唾液腺学会
    • Data Source
      KAKENHI-PROJECT-19J40027
  • [Presentation] サクソンテストはすべての患者で有効か -非シェーグレン症候群患者における調査-2021

    • Author(s)
      皆木 瞳、山中惠賀、大内淑代、 阪井丘芳
    • Organizer
      日本老年歯科医学会
    • Data Source
      KAKENHI-PROJECT-18K17223
  • [Presentation] 高齢者の服薬と口腔乾燥症の実態解明-治療法の確立を目指して-2021

    • Author(s)
      皆木 瞳、山中 賀惠、野原 幹司、大内 淑代、阪井 丘芳
    • Organizer
      日本唾液腺学会
    • Data Source
      KAKENHI-PROJECT-18K17223
  • [Presentation] サクソンテストはすべての患者で有効か -非シェーグレン症候群患者における調査-2021

    • Author(s)
      皆木 瞳、山中惠賀、大内淑代、 阪井丘芳
    • Organizer
      日本老年歯科医学会
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 非シェーグレン症候群患者におけるサクソンテストの有効性の検討2021

    • Author(s)
      皆木 瞳、大内 淑代、阪井 丘芳
    • Organizer
      日本口腔科学会
    • Data Source
      KAKENHI-PROJECT-18K17223
  • [Presentation] 唾液腺組織の再生過程は発生過程を模倣しているか?2021

    • Author(s)
      皆木 瞳、宇佐美 悠、酒井 学、井階一樹、大内 淑代、阪井 丘芳
    • Organizer
      日本口腔科学会
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] サクソンテストはすべての患者で有効か -非シェーグレン症候群患者における調査-2021

    • Author(s)
      皆木 瞳、山中惠賀、大内淑代、 阪井丘芳
    • Organizer
      日本老年歯科医学会
    • Data Source
      KAKENHI-PROJECT-19J40027
  • [Presentation] 非シェーグレン症候群患者におけるサクソンテストの有効性の検討2021

    • Author(s)
      皆木 瞳、大内 淑代、阪井 丘芳
    • Organizer
      日本口腔科学会
    • Data Source
      KAKENHI-PROJECT-21K10093
  • [Presentation] 唾液腺障害モデルから探索する再生医療への可能性2020

    • Author(s)
      皆木 瞳
    • Organizer
      歯科基礎医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19J40027
  • [Presentation] 発生過程の解明に基づく唾液腺再生への可能性2020

    • Author(s)
      皆木 瞳, 宇佐美 悠, 酒井 学, 大内 淑代, 阪井 丘芳
    • Organizer
      日本歯科基礎医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K17223
  • [Presentation] 唾液腺障害モデルから探索する再生医療への可能性2019

    • Author(s)
      皆木 瞳
    • Organizer
      歯科基礎医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19J40027
  • [Presentation] 唾液腺障害モデルから探索する再生医療への可能性2019

    • Author(s)
      皆木 瞳, 宇佐美 悠, 井階 一樹, 阪井 丘芳
    • Organizer
      日本歯科基礎医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K17223
  • [Presentation] 唾液腺性差とRunx1cKOマウスの唾液分泌制御機構2017

    • Author(s)
      皆木 瞳
    • Organizer
      歯科基礎医学会
    • Data Source
      KAKENHI-PROJECT-16K20573
  • [Presentation] Pilocarpine benefit in stem cell therapy2017

    • Author(s)
      Ono Hitomi
    • Organizer
      Gordon research conference
    • Place of Presentation
      Texas, U.S.A
    • Year and Date
      2017-02-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20573
  • [Presentation] 口腔乾燥症状に対するピロカルピンの継続的服用の有効性2016

    • Author(s)
      小野 瞳
    • Organizer
      日本基礎歯科医学界
    • Place of Presentation
      札幌コンベンションセンター、札幌、北海道
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-16K20573
  • 1.  阪井 丘芳 (90379082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  井階 一樹 (00849432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  田中 信和 (20570295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  山本 朗仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  橋本 登
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  加納 史也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  呉本 晃一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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