KASHIYAMA TOMOKO 樫山智子

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Kashiyama Tomoko 樫山智子

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Researcher Number	70755719
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京大学, 医学部附属病院, 届出研究員 2017 – 2018: 東京大学, 医学部附属病院, 登録研究員 2015 – 2016: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 卵巣癌 / 婦人科悪性腫瘍 / 分子標的薬 / アポトーシス / 卵巣明細胞癌 / PI3K/mTOR阻害薬 / 酸化ストレス / 悪性腫瘍関連血栓症 / 血栓症 / 卵巣腫瘍 … More / 血栓治療 / 血小板活性化 / 血小板凝集塊 / がん関連血栓症 / 明細胞癌 / MDM2阻害薬 / Bcl-2 family / 子宮体癌 / 婦人科腫瘍 / 卵巣明細胞腺癌 / 分子標的治療 / 癌 / PI3K/mTOR阻害剤 Less

Elucidation of the mechanism of cancer-related thrombosis in ovarian clear cell carcinomaPrincipal Investigator
- Principal Investigator
  
  KASHIYAMA TOMOKO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Development of a new treatment based on induction of cell death by BH3 mimetics in ovarian cancerPrincipal Investigator
- Principal Investigator
  
  Kashiyama Tomoko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Establishment of novel molecular targeted therapy focused on apoptosis induction in ovarian clear cell adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  Kashiyama Tomoko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo

All 2019 2018 2016 2015 Other

All Journal Article Presentation Other

[Journal Article] A low albumin to globulin ratio with a high serum globulin level is a prognostic marker for poor survival in cervical cancer patients treated with radiation based therapy2019
- Author(s)
  Yoshino Yasunori、Taguchi Ayumi、Shimizuguchi Takuya、Nakajima Yujiro、Takao Maki、Kashiyama Tomoko、Furusawa Akiko、Kino Nao、Yasugi Toshiharu
- Journal Title
  
  International Journal of Gynecologic Cancer
  
  Volume: 29 Issue: 1 Pages: 17-22
- DOI
  10.1136/ijgc-2018-000025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16832, KAKENHI-PROJECT-18K16757
[Journal Article] Lymphopenia after induction chemotherapy correlates with incomplete surgical resection in patients with advanced ovarian cancer2018
- Author(s)
  Yoshino Yasunori、Taguchi Ayumi、Takao Maki、Kashiyama Tomoko、Furusawa Akiko、Uno Masaya、Okada Satoshi、Kino Nao、Yasugi Toshiharu
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 24 Issue: 4 Pages: 428-436
- DOI
  10.1007/s10147-018-1374-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16832, KAKENHI-PROJECT-18K16757
[Journal Article] Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies.2016
- Author(s)
  Oda K, Ikeda Y, Kashiyama T　et al.
- Journal Title
  
  The journal of obstetrics and gynecological research
  
  Volume: 42 Issue: 7 Pages: 757-62
- DOI
  10.1111/jog.13018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06173, KAKENHI-PROJECT-15K10704
[Journal Article] Synergistic antitumor effects of combination of PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging.2016
- Author(s)
  Inaba K, Oda K, Aoki K, Sone K, Ikeda Y, Miyasaka A, Kashiyama T, Fukuda T, Makii C, Arimoto T, Wada-Hiraike O, Kawana K, Yano T, Osuga Y, Fujii T
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 20 Pages: 29577-29591
- DOI
  10.18632/oncotarget.8807
- NAID
  120005820854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01425, KAKENHI-PUBLICLY-16H01447, KAKENHI-PROJECT-15H06173, KAKENHI-PROJECT-26290053, KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-16KT0069, KAKENHI-PROJECT-15K10704
[Journal Article] MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.2016
- Author(s)
  Makii C, Oda K, Ikeda Y, Sone K, Hasegawa K, Uehara Y, Nishijima A, Asada K, Koso T, Fukuda T, Inaba K, Oki S, Machino H, Kojima M, Kashiyama T, Mori-Uchino M, Arimoto T, Wada-Hiraike O, Yano KK, Fujiwara K, Aburatani H, Osuga Y, Fujii T.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 46 Pages: 75328-75338
- DOI
  10.18632/oncotarget.12175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15H06173, KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-16K20176
[Journal Article] 卵巣癌新規治療薬候補PI3K/mTOR 阻害薬DS–7423によるTP53依存性アポトーシス誘導能の活性化2015
- Author(s)
  織田克利、樫山智子
- Journal Title
  
  産科と婦人科
  
  Volume: vol.10 Pages: 1113-1118
- Data Source
  KAKENHI-PROJECT-15H06173
[Presentation] ベバシズマブ時代の卵巣がん再発―そのプラチナ感受性の判断は妥当か―2018
- Author(s)
  水野祥、樫山智子
- Organizer
  2018/6/17 第135回関東連合産科婦人科学会　総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K16832
[]
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1. 田口歩 (60756782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 谷川道洋 (70706944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. AOKI Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KASHIYAMA TOMOKO 樫山 智子

Kashiyama Tomoko 樫山 智子

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of cancer-related thrombosis in ovarian clear cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new treatment based on induction of cell death by BH3 mimetics in ovarian cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of novel molecular targeted therapy focused on apoptosis induction in ovarian clear cell adenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A low albumin to globulin ratio with a high serum globulin level is a prognostic marker for poor survival in cervical cancer patients treated with radiation based therapy2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lymphopenia after induction chemotherapy correlates with incomplete surgical resection in patients with advanced ovarian cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic antitumor effects of combination of PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 卵巣癌新規治療薬候補PI3K/mTOR 阻害薬DS&#8211;7423によるTP53依存性アポトーシス誘導能の活性化2015

Author(s)

Journal Title

Data Source

[Presentation] ベバシズマブ時代の卵巣がん再発―そのプラチナ感受性の判断は妥当か―2018

Author(s)

Organizer

Data Source

[]

[]

KASHIYAMA TOMOKO 樫山智子

Kashiyama Tomoko 樫山智子

[Journal Article] 卵巣癌新規治療薬候補PI3K/mTOR 阻害薬DS–7423によるTP53依存性アポトーシス誘導能の活性化2015