FURUIKE Yoshihiko 古池美彦

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Furuike Yoshihiko 古池美彦

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Researcher Number	70757400
Other IDs
Affiliation (Current)	2025: 分子科学研究所, 協奏分子システム研究センター, 助教
Affiliation (based on the past Project Information) *help	2016 – 2024: 分子科学研究所, 協奏分子システム研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Structural biochemistry Except Principal Investigator Broad Section G / Structural biochemistry / Biophysics
Keywords	Principal Investigator 時計タンパク質 / 概日時計 / ATP加水分解反応 / リン酸化 / ATP加水分解 / 概日リズム / タンパク質進化 / ATPase / シアノバクテリア / X線結晶構造解析 … More / KaiC / アロステリー / 自己脱リン酸化・自己リン酸化 / 祖先配列 / リン酸化・脱リン酸化反応 / 生物時計 / 時計タンパク質KaiC … More Except Principal Investigator 生物時計 / シアノバクテリア / 概日時計 / 分子進化 / 周波数特性 / 24時間周期 / タンパク質 / リズム / アロステリー / リン酸化 / ATPase / KaiC / 温度補償性 Less

Complex Allosteric Regulations in Clock ProteinsPrincipal Investigator
- Principal Investigator
  
  古池美彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Institute for Molecular Science
Simplifying complexity and diversity of circadian clocks
- Principal Investigator
  
  秋山修志
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  Institute for Molecular Science
Atomic Structures of Clock Protein Reflecting Ancient Earth's RotationPrincipal Investigator
- Principal Investigator
  
  Furuike Yoshihiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Institute for Molecular Science
An Integrated Multi-scale Approach for Studying Cyanobacterial Circadian Clock System
- Principal Investigator
  
  Akiyama Shuji
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biophysics
- Research Institution
  Institute for Molecular Science
生物時計システムの周期と温度補償制御ロジックの構造化学的解明
- Principal Investigator
  
  秋山修志
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Institute for Molecular Science
Structures and Activities of Clock Protein KaiC Encoding the Earth Rotation from the Ancient TimePrincipal Investigator
- Principal Investigator
  
  Furuike Yoshihiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Institute for Molecular Science

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] The priming phosphorylation of KaiC is activated by the release of its autokinase autoinhibition2024
- Author(s)
  Furuike Yoshihiko、Onoue Yasuhiro、Saito Shinji、Mori Toshifumi、Akiyama Shuji
- Journal Title
  
  biorxiv
  
  Volume: -
- DOI
  10.1101/2024.03.21.584037
- Open Access
- Data Source
  KAKENHI-PROJECT-22K15051, KAKENHI-PROJECT-22K19279, KAKENHI-PROJECT-22H04984
[Journal Article] Structure-function relationship of KaiC around dawn2024
- Author(s)
  Furuike Yoshihiko、Yamashita Eiki、Akiyama Shuji
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 21 Issue: 1 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v21.0001
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15051, KAKENHI-PROJECT-22K19279, KAKENHI-PROJECT-22H04984
[Journal Article] 時計タンパク質KaiCの構造にみる概日リズムの起源2023
- Author(s)
  古池美彦
- Journal Title
  
  日本結晶学会誌
  
  Volume: 65 Pages: 113-121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04984
[Journal Article] Master allostery in clock protein KaiC orchestrates circadian rhythm2023
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Shuji Akiyama
- Journal Title
  
  Pring-8/SACLA Research Frontiers 2022
  
  Volume: - Pages: 26-27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04984
[Journal Article] 生命は「アロステリー」でリズムを奏でる2023
- Author(s)
  古池美彦
- Journal Title
  
  生物物理
  
  Volume: 63 Pages: 173-174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04984
[Journal Article] Cross-scale analysis of temperature compensation in the cyanobacterial circadian clock system2022
- Author(s)
  Furuike Yoshihiko、Ouyang Dongyan、Tominaga Taiki、Matsuo Tatsuhito、Mukaiyama Atsushi、Kawakita Yukinobu、Fujiwara Satoru、Akiyama Shuji
- Journal Title
  
  Communications Physics
  
  Volume: 5 Issue: 1 Pages: 75-75
- DOI
  10.1038/s42005-022-00852-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-20H03232, KAKENHI-PROJECT-22K06175, KAKENHI-PROJECT-22K15051, KAKENHI-ORGANIZER-21H05129, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-22H04984
[Journal Article] Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system2022
- Author(s)
  Mukaiyama Atsushi、Furuike Yoshihiko、Yamashita Eiki、Akiyama Shuji
- Journal Title
  
  Biochemical Journal
  
  Volume: 479 Issue: 14 Pages: 1505-1515
- DOI
  10.1042/bcj20210544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06175, KAKENHI-PROJECT-22K15051, KAKENHI-ORGANIZER-21H05129, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-22H04984
[Journal Article] 放射光X線で照らす時計タンパク質KaiCの概日振動メカニズム2022
- Author(s)
  古池美彦
- Journal Title
  
  SPring-8/SACLA利用者情報
  
  Volume: 27 (4) Pages: 306-310
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15051
[Journal Article] Regulation mechanisms of the dual ATPase in KaiC2022
- Author(s)
  Furuike Yoshihiko、Mukaiyama Atsushi、Koda Shin-ichi、Simon Damien、Ouyang Dongyan、Ito-Miwa Kumiko、Saito Shinji、Yamashita Eiki、Nishiwaki-Ohkawa Taeko、Terauchi Kazuki、Kondo Takao、Akiyama Shuji
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 19
- DOI
  10.1073/pnas.2119627119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-22K06175, KAKENHI-PROJECT-22K15051, KAKENHI-ORGANIZER-21H05129, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-22H04984, KAKENHI-PROJECT-21H04676, KAKENHI-PROJECT-19K05833
[Journal Article] 放射光X線で照らす時計タンパク質KaiCの概日振動メカニズム2022
- Author(s)
  古池美彦
- Journal Title
  
  SPring-8/SACLA利用者情報
  
  Volume: 27 (4) Pages: 306-310
- Open Access
- Data Source
  KAKENHI-PROJECT-22H04984
[Journal Article] Slow and temperature-compensated autonomous disassembly of KaiB–KaiC complex2022
- Author(s)
  Simon Damien、Mukaiyama Atsushi、Furuike Yoshihiko、Akiyama Shuji
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0008
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16061, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-17H06165, KAKENHI-ORGANIZER-21H05129
[Journal Article] Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria2022
- Author(s)
  Furuike Yoshihiko、Mukaiyama Atsushi、Ouyang Dongyan、Ito-Miwa Kumiko、Simon Damien、Yamashita Eiki、Kondo Takao、Akiyama Shuji
- Journal Title
  
  Science Advances
  
  Volume: 8 Issue: 15
- DOI
  10.1126/sciadv.abm8990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-22K06175, KAKENHI-PROJECT-22K15051, KAKENHI-ORGANIZER-21H05129, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-22H04984
[Journal Article] Tuning the circadian period of cyanobacteria up to 6.6 days by the single amino acid substitutions in KaiC2020
- Author(s)
  Ito-Miwa Kumiko、Furuike Yoshihiko、Akiyama Shuji、Kondo Takao
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 34 Pages: 20926-20931
- DOI
  10.1073/pnas.2005496117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165
[Journal Article] KaiC from a cyanobacterium Gloeocapsa sp. PCC 7428 retains functional and structural properties required as the core of circadian clock system.2019
- Author(s)
  Mukaiyama A, Ouyang D, Furuike Y, Akiyama S
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 131 Pages: 67-73
- DOI
  10.1016/j.ijbiomac.2019.03.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-16K14685, KAKENHI-PROJECT-19K16061
[Journal Article] Development and optimization of expression, purification and ATPase assay of KaiC for medium throughput screening of circadian clock mutants in cyanobacteria2019
- Author(s)
  Ouyang D, Furuike Y, Mukaiyama A, Ito-Miwa K, Kondo T and Akiyama S
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 20 Issue: 11 Pages: 2789-2789
- DOI
  10.3390/ijms20112789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-17H01427
[Journal Article] A kinetic mechanism gating the assembly of KaiB-KaiC complex in the cyanobacterial circadian clock system2019
- Author(s)
  Mukaiyama A, Furuike Y, Akiyama S
- Journal Title
  
  Biological Rhythms
  
  Volume: - Pages: 29-34
- Data Source
  KAKENHI-PROJECT-17H06165
[Journal Article] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB2018
- Author(s)
  Mukaiyama A, Furuike Y, Abe J, Yamashita E, Kondo T, Akiyama S
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8803-8803
- DOI
  10.1038/s41598-018-27131-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-16K14685
[Journal Article] 変化し続ける概日時計研究のかたち2018
- Author(s)
  秋山修志、古池美彦、向山厚
- Journal Title
  
  時間生物学
  
  Volume: 24-2 Pages: 92-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14685
[Journal Article] 変化し続ける概日時計のかたち2018
- Author(s)
  秋山　修志、古池　美彦、向山　厚
- Journal Title
  
  時間生物学
  
  Volume: Vol. 24, No. 2 Pages: 92-99
- Open Access
- Data Source
  KAKENHI-PROJECT-17H06165
[Journal Article] Cyanobacterial circadian clock system: how and why can it be so slow and stable?2017
- Author(s)
  Akiyama S, Mukaiyama A, Abe J, Furuike Y
- Journal Title
  
  Biological Clocks: with reference to suprachiasmatic nucleus
  
  Volume: - Pages: 73-77
- Data Source
  KAKENHI-PROJECT-17H06165
[Journal Article] Cyanobacterial circadian clock system: how and why can it be so slow and stable?2017
- Author(s)
  Shuji Akiyama, Atsushi Akiyama, Jun Abe, Yoshihiko Furuike
- Journal Title
  
  Biological Clocks: with reference to suprachiasmatic nucleus
  
  Volume: - Pages: 73-77
- Data Source
  KAKENHI-PROJECT-16K14685
[Journal Article] Observation of ADP-Ribose Pyrophosphatase Reaction in Crystalline-State Induced by Mn（II）Ion Binding2016
- Author(s)
  古池美彦、宮原郁子、神谷信夫
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 58 Issue: 4 Pages: 186-192
- DOI
  10.5940/jcrsj.58.186
- NAID
  130005261612
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14685
[Journal Article] ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors2016
- Author(s)
  Yoshihiko Furuike, Yuka Akita, Ikuko Miyahara, and Nobuo Kamiya
- Journal Title
  
  Biochemistry
  
  Volume: 55(12) Issue: 12 Pages: 1801-1812
- DOI
  10.1021/acs.biochem.5b00886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14685
[Journal Article] Accelerating in vitro studies on circadian clock systems using an automated sampling device2016
- Author(s)
  Furuike Y, Abe J, Mukaiyama A, Akiyama S
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 13 Issue: 0 Pages: 235-241
- DOI
  10.2142/biophysico.13.0_235
- NAID
  130005249808
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00785, KAKENHI-PROJECT-16K14685, KAKENHI-PROJECT-24000016
[Presentation] ATPase Regulation in KaiC Triggers Assembly and Disassembly of Clock Proteins in Cyanobacteria2023
- Author(s)
  Yoshihiko Furuike, Shuji Akiyama
- Organizer
  日本生物物理学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 概日時計を指揮する時計タンパク質KaiCのアクセル・ブレーキ制御2023
- Author(s)
  古池美彦、向山厚、秋山修志
- Organizer
  令和4年度日本生物物理学会中部支部研究会
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 概日時計を指揮する時計タンパク質KaiCのアクセル・ブレーキ制御2023
- Author(s)
  古池美彦
- Organizer
  日本生物物理学会中部支部例会
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] 概日時計タンパク質のアロステリックな律動を捉える構造生物化学2023
- Author(s)
  古池美彦
- Organizer
  第94回SPring-8先端利用技術ワークショップ/大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 時刻情報を生成／統合／伝達するシアノバクテリア時計タンパク質KaiCの分子構造2023
- Author(s)
  古池美彦
- Organizer
  第30回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] ATPase Regulation in KaiC Triggers Assembly and Disassembly of Clock Proteins in Cyanobacteria2023
- Author(s)
  Yoshihiko FURUIKE and Shuji AKIYAMA
- Organizer
  日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] 概日時計タンパク質のアロステリックな律動を捉える構造生物化学2023
- Author(s)
  古池美彦
- Organizer
  大阪大学蛋白研セミナー/SPring-8 先端利用技術ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] 時刻情報を生成/統合/伝達するシアノバクテリア時計タンパク質KaiCの構造2023
- Author(s)
  古池美彦、秋山修志
- Organizer
  日本時間生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] Visualizing a Day of Circadian Clock at Atomic Resolution2022
- Author(s)
  古池美彦
- Organizer
  第60回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 概日リズムを奏でる時計タンパク質のアロステリック制御機構の解明2022
- Author(s)
  古池美彦
- Organizer
  令和4年度日本結晶学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 原子レベルでみた時計タンパク質KaiCの概日サイクル2022
- Author(s)
  古池美彦
- Organizer
  2021年度日本生物物理学会中部支部例会
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] シアノバクテリア概日時計のアロステリー機構2022
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] Exploring ancient origins of the circadian clock system through molecular evolution2022
- Author(s)
  Mukaiyama A, Furuike Y, Akiyama S
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 分子進化的アプローチに基づく概日時計の進化的起源の探究2022
- Author(s)
  向山厚、古池美彦、秋山修志
- Organizer
  令和3年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 概日リズムを奏でる時計タンパク質のアロステリック制御機構の解明2022
- Author(s)
  古池美彦
- Organizer
  日本結晶学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] 概日振動を統御する時計タンパク質KaiCの原子メカニズム2022
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本時間生物学会年会
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] 放射光X線で照らす時計タンパク質KaiCの概日振動メカニズム2022
- Author(s)
  古池美彦
- Organizer
  SPring-8シンポジウム2022
- Invited
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 時計タンパク質のアロステリーに基づく複雑なシアノバクテリア概日振動の理解2022
- Author(s)
  古池美彦
- Organizer
  2021年度名古屋リズム研究会
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] KaiCの２つのATP加水分解サイトを捉える構造解析2022
- Author(s)
  古池美彦
- Organizer
  CyanoClock4.0
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] 放射光X線で照らす時計タンパク質KaiCの概日振動メカニズム2022
- Author(s)
  古池美彦
- Organizer
  SPring-8シンポジウム2022
- Invited
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] KaiCの２つのATP加水分解サイトを捉える構造解析2022
- Author(s)
  古池美彦
- Organizer
  CyanoClock4.0
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] 概日振動を統御する時計タンパク質KaiCの原子メカニズム2022
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  第29回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] シアノバクテリア概日時計のアロステリー機構2022
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22H04984
[Presentation] Visualizing a Day of Circadian Clock at Atomic Resolution2022
- Author(s)
  古池美彦
- Organizer
  日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15051
[Presentation] Mechanisms behind the disassembly of KaiB-KaiC complex2022
- Author(s)
  Damien S, Mukaiyama A, Furuike Y, Akiyama S
- Organizer
  令和3年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質のアロステリーに基づく複雑なシアノバクテリア概日振動の理解2022
- Author(s)
  古池美彦
- Organizer
  第五回名古屋リズム研究会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 原子レベルでみた時計タンパク質KaiCの概日サイクル2022
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  令和3年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] シアノバクテリア概日時計における進化的多様性の分子メカニズム2021
- Author(s)
  向山厚、古池美彦、秋山修志
- Organizer
  令和2年度　生物物理中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 藍藻の概日リズムを制御する時計タンパク質KaiCのアロステリー2021
- Author(s)
  古池美彦, 向山厚, 欧陽東彦, 伊藤(三輪)久美子,Damien SIMON, 山下栄樹, 近藤孝男, 秋山修志
- Organizer
  2021年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] Exploring ancient origin of circadian oscillation through KaiC evolution2021
- Author(s)
  Mukaiyama A, Furuike Y, Akiyama S
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質KaiCにおけるリン酸化過程の原子レベルでの理解2021
- Author(s)
  古池美彦
- Organizer
  2020年度名古屋リズム研究会
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] Core Allosteric Regulation in Cyanobacterial Circadian Clock Protein KaiC2021
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Dongyan Ouyang, Kumiko Ito-Miwa, Damien Simon, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  2021年度日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] Core Allosteric Regulation in Cyanobacterial Circadian Clock Protein KaiC2021
- Author(s)
  Furuike Y, Mukaiyama A, Ouyang D, Ito-Miwa K, Simon D, Yamashita E, Akiyama S
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Modifying Kai cysteine mutants for investigating the interaction of Kai C, A, and B2021
- Author(s)
  Dongyan Ouyang, Atsushi Mukaiyama, Yoshihiko Furuike and Shuji Akiyama
- Organizer
  令和2年度　生物物理中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Lifetime analysis of nucleotides bound to KaiC2021
- Author(s)
  Simon D, Mukaiyama A, Furuike Y, Akiyama S
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Disassembly kinetics of the KaiBC complex in the cyanobacterial clock system2021
- Author(s)
  D. Simon, A. Mukaiyama, Y. Furuike and S. Akiyama
- Organizer
  令和2年度　生物物理中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] シアノバクテリア概日時計を駆動する時計タンパク質KaiCの動作転換メカニズム2020
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  第 27 回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] シアノバクテリア概日時計を駆動する時計タンパク質KaiCの動作転換メカニズム2020
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  第 27 回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Seeking for evolutionary diversity of Kai-protein clock system in cyanobacteria2019
- Author(s)
  Atsushi Mukaiyama, Dongyan Ouyang, Yoshihiko Furuike and Shuji Akiyama
- Organizer
  XVI Congress of the European Biological Rhythms Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Capability of the ATPase-based Screening System to Search Structural Units Determining the Function of Cyanobacterial Clock Protein KaiC2019
- Author(s)
  Ouyang D, Furuike Y, Mukaiyama A, Miwa K, Kondo T, Akiyama S
- Organizer
  第26回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質KaiCのリン酸化ドメインにおける水分子の同定2019
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本結晶学会2019年度年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] シアノバクテリアGloeocapsa sp. PCC 7428株由来KaiCの機能解析2019
- Author(s)
  向山　厚、欧陽　東彦、古池　美彦、秋山　修志
- Organizer
  平成30年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Structural Relationships between ATP-hydrolysis and Phosphorylation Domains in Cyanobacterial Clock Protein KaiC2019
- Author(s)
  Furuike Y, Mukaiyama A, Yamashita E, Kondo T, Akiyama S
- Organizer
  V World Congress of Chronobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] A screening through alanine scanning-mutagenesis to search structural units determining the function of cyanobacterial clock protein KaiC2019
- Author(s)
  Ouyang D, Furuike Y, Mukaiyama A, Miwa K, Kondo T, Akiyama S
- Organizer
  Cyanoclock2.0
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 好熱性藍藻に由来する時計タンパク質KaiCの活性部位における水和構造2019
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本生物物理学会中部支部例会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Structural Relationships between ATP-hydrolysis and Phosphorylation Domains in Cyanobacterial Clock Protein KaiC2019
- Author(s)
  Yoshihiko FURUIKE, Atsushi MUKAIYAMA, Eiki YAMASHITA, Takao KONDO, and Shuji AKIYAMA
- Organizer
  V World Congress of Chronobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] Cumulative Effect of Double Mutation on Cyanobacterial Clock Protein KaiC2019
- Author(s)
  Marie V, Furuike Y, Akiyama S
- Organizer
  Cyanoclock2.0
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 好熱性藍藻に由来する時計タンパク質KaiCの活性部位における水和構造2019
- Author(s)
  古池　美彦、向山　厚、山下　栄樹、近藤　孝男、秋山　修志
- Organizer
  平成30年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Structural Diversity of KaiC Hexamer in Cyanobacterial Circadian Clock2019
- Author(s)
  Furuike Y, Mukaiyama A, Yamashita E, Kondo T, Akiyama S
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Development of a medium-throughput in vitro screening system for circadian clock mutants of KaiC in cyanobacteria2019
- Author(s)
  Ouyang D, Mukaiyama A, Furuike Y, Miwa K, Kondo T, Akiyama S
- Organizer
  V World Congress of Chronobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質KaiCのリン酸化ドメインにおける水分子の同定2019
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] In vitro ATPase-based screening of circadian clock mutants of KaiC in cyanobacterial circadian clock system2019
- Author(s)
  Ouyang D, Furuike Y, Mukaiyama A, Miwa K, Kondo T, Akiyama S
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Evolutionary diversity of Kai-protein clock in cyanobacteria2019
- Author(s)
  Mukaiyama A, Ouyang D, Furuike Y, Akiyama S
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Structural Diversity of KaiC Hexamer in Cyanobacterial Circadian Clock2019
- Author(s)
  Yoshihiko FURUIKE, Atsushi MUKAIYAMA, Eiki YAMASHITA, Takao KONDO, and Shuji AKIYAMA
- Organizer
  日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K16061
[Presentation] 多種KaiCの機能解析によるシアノバクテリア生物時計の進化的多様性の考察2019
- Author(s)
  向山厚、欧陽東彦、古池美彦、秋山修志
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Identification of Clock Protein KaiC Mutants Losing Temperature Compensation Ability2018
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  平成29年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質 KaiC に組み込まれたアロステリック制御2018
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Searching Allosteric Pathways in Clock Protein KaiC Responsible for Temperature Compensation2018
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質KaiCに組み込まれたアロステリック制御2018
- Author(s)
  古池美彦、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  CyanoClock 1.0
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB via a conformational selection mechanism2018
- Author(s)
  Atsushi Mukaiyama, Yoshihiko Furuike, Eiki Yamashita, Takao Kondo and Shuji Akiyama
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質KaiCの機能発現に関わる動的構造変化の解析2018
- Author(s)
  向山　厚、古池　美彦、山下　栄樹、近藤　孝男、秋山　修志
- Organizer
  平成29年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Optimizing expression and purification of His-tagged KaiC proteins for an effective in vitro screening of circadian clock mutants in cyanobacteria2018
- Author(s)
  Dongyan Ouyang, Atsushi Mukaiyama, Yoshihiko Furuike and Shuji Akiyama
- Organizer
  第二回名古屋リズム研究会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Optimizing the protocol for accelerating the analysis of the ATPase activity of circadian clock protein KaiC2018
- Author(s)
  Dongyan Ouyang, Atsushi Mukaiyama, Yoshihiko Furuike and Shuji Akiyama
- Organizer
  CyanoClock 1.0
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Identification of Clock Protein KaiC Mutants Losing Temperature Compensation Ability2018
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, Shuji Akiyama
- Organizer
  第二回名古屋リズム研究会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Searching Allosteric Pathways in Clock Protein KaiC Responsible for Temperature Compensation2018
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] 時計タンパク質KaiCに組み込まれたアロステリック制御2018
- Author(s)
  古池　美彦、向山　厚、山下　栄樹、近藤　孝男、秋山　修志
- Organizer
  CyanoClock 1.0
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] シアノバクテリア生物時計の分子起源とその進化2018
- Author(s)
  向山　厚、古池　美彦、秋山　修志
- Organizer
  第25回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Optimizing expression and purification of His-tagged KaiC proteins for an effective in vitro screening of circadian clock mutants in cyanobacteria2018
- Author(s)
  Dongyan Ouyang, Atsushi Mukaiyama, Yoshihiko Furuike and Shuji Akiyama
- Organizer
  平成29年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] 時計タンパク質 KaiC に組み込まれたアロステリック制御2018
- Author(s)
  古池　美彦、向山　厚、山下　栄樹、近藤　孝男、秋山　修志
- Organizer
  日本結晶学会2018年度年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Optimizing the protocol for accelerating the analysis of the ATPase activity of circadian clock protein KaiC2018
- Author(s)
  Dongyan Ouyang, Atsushi Mukaiyama, Yoshihiko Furuike and Shuji Akiyama
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Identification of Clock Protein KaiC Mutants Losing Temperature Compensation Ability2017
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] リン酸化および脱リン酸化した時計タンパク質KaiCの結晶構造解析2017
- Author(s)
  古池　美彦、向山　厚、山下　栄樹、近藤　孝男、秋山　修志
- Organizer
  平成29年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] リン酸化および脱リン酸化した時計タンパク質KaiCの結晶構造解析2017
- Author(s)
  古池　美彦、向山　厚、山下　栄樹、近藤　孝男、秋山　修志
- Organizer
  生理研研究会「クライオ電子顕微鏡によるタンパク質の高分解能単粒子構造解析」
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Functional and Structural Study on Peptide Isomerization in KaiC2017
- Author(s)
  Yoshihiko FURUIKE, Jun ABE, Atsushi MUKAIYAMA1, Eiki YAMASHITA,　Takao KONDO and Shuji AKIYAMA
- Organizer
  Circadian Clock of Cyanobacteria during 1991-2017
- Place of Presentation
  愛知県名古屋市名古屋大学
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Identification of Clock Protein KaiC Mutants Losing Temperature Compensation Ability2017
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  平成29年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] シアノバクテリア時計タンパク質KaiCにおける主鎖異性化反応の意義2017
- Author(s)
  古池美彦、阿部淳、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  日本生物物理学会中部支部例会
- Place of Presentation
  愛知県名古屋市名古屋大学
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Identification of Clock Protein KaiC Mutants Losing Temperature Compensation Ability2017
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] Identification of Clock Protein KaiC Mutants Losing Temperature Compensation Ability2017
- Author(s)
  Yoshihiko Furuike, Atsushi Mukaiyama, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  第二回名古屋リズム研究会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] リン酸化および脱リン酸化した時計タンパク質KaiCの結晶構造解析2017
- Author(s)
  古池美彦，向山厚, 山下栄樹, 近藤孝男, 秋山修志
- Organizer
  平成29年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] リン酸化および脱リン酸化した時計タンパク質KaiCの結晶構造解析2017
- Author(s)
  古池美彦，向山厚, 山下栄樹, 近藤孝男, 秋山修志
- Organizer
  クライオ電子顕微鏡によるタンパク質の高分解能単粒子構造解析
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Biochemical characterization of KaiC ATPases from cyanobcateria living in various habitants2017
- Author(s)
  向山　厚、古池　美彦、秋山　修志
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06165
[Presentation] KaiCにおける主鎖異性化反応の意義2016
- Author(s)
  古池美彦、阿部淳、向山厚、山下栄樹、近藤孝男、秋山修志
- Organizer
  時間生物学会年会
- Place of Presentation
  愛知県名古屋市名古屋大学
- Data Source
  KAKENHI-PROJECT-16K14685
[Presentation] Structural Differences between Phosphorylated and Dephosphorylated States of Clock Protein KaiC2016
- Author(s)
  Yoshihiko Furuike, Jun Abe, Eiki Yamashita, Takao Kondo, and Shuji Akiyama
- Organizer
  日本生物物理学会年会
- Place of Presentation
  茨城県つくば市つくば国際会議場
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K14685

1. Akiyama Shuji (50391842)

# of Collaborated Projects: 3 results

# of Collaborated Products: 49 results
2. 藤原悟 (10354888)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 上久保裕生 (20311128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 近藤孝男 (10124223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
5. 片岡幹雄 (30150254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 成田哲博 (30360613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 向山厚 (80647446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

FURUIKE Yoshihiko 古池 美彦

Furuike Yoshihiko 古池 美彦

Research Projects

Research Products

Co-Researchers

Complex Allosteric Regulations in Clock ProteinsPrincipal Investigator

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Simplifying complexity and diversity of circadian clocks

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Atomic Structures of Clock Protein Reflecting Ancient Earth's RotationPrincipal Investigator

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An Integrated Multi-scale Approach for Studying Cyanobacterial Circadian Clock System

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生物時計システムの周期と温度補償制御ロジックの構造化学的解明

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Structures and Activities of Clock Protein KaiC Encoding the Earth Rotation from the Ancient TimePrincipal Investigator

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[Journal Article] The priming phosphorylation of KaiC is activated by the release of its autokinase autoinhibition2024

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[Journal Article] Structure-function relationship of KaiC around dawn2024

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[Journal Article] 時計タンパク質KaiCの構造にみる概日リズムの起源2023

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[Journal Article] Master allostery in clock protein KaiC orchestrates circadian rhythm2023

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[Journal Article] 生命は「アロステリー」でリズムを奏でる2023

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[Journal Article] Cross-scale analysis of temperature compensation in the cyanobacterial circadian clock system2022

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[Journal Article] Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system2022

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[Journal Article] 放射光X線で照らす時計タンパク質KaiCの概日振動メカニズム2022

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[Journal Article] Regulation mechanisms of the dual ATPase in KaiC2022

FURUIKE Yoshihiko 古池美彦

Furuike Yoshihiko 古池美彦