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Maki Takakuni  眞木 崇州

ORCIDConnect your ORCID iD *help
Researcher Number 70762334
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help 2020 – 2023: 京都大学, 医学研究科, 講師
2016 – 2018: 京都大学, 医学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 46010:Neuroscience-general-related / Neurochemistry/Neuropharmacology
Keywords
Principal Investigator
オリゴデンドロサイト前駆細胞 / 形質変化 / 再生医療 / 細胞治療 / 低酸素 / 血管新生 / 脳梗塞 / オリゴデンドロサイト / 血管周皮細胞 / 神経グリア血管単位 / アミロイドβ / 血液脳関門 / アルツハイマー病
  • Research Projects

    (2 results)
  • Research Products

    (11 results)
  •  Elucidation of phenotype changes of oligodendrocyte precursor cells in cerebral infarction and therapeutic applicationPrincipal Investigator

    • Principal Investigator
      Maki Takakuni
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      Kyoto University
  •  Elucidation of the roles of oligodendrocytes on Alzheimer's disease and its clinical applicationPrincipal Investigator

    • Principal Investigator
      Maki Takakuni
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyoto University

All 2024 2023 2021 2018 2017

All Journal Article Presentation

  • [Journal Article] Efficacy of oligodendrocyte precursor cells as delivery vehicles for single-chain variable fragment to misfolded SOD1 in ALS rat model2023

    • Author(s)
      Minamiyama Sumio、Sakai Madoka、Yamaguchi Yuko、Kusui Makiko、Wada Hideki、Hikiami Ryota、Tamaki Yoshitaka、Asada-Utsugi Megumi、Shodai Akemi、Makino Akiko、Fujiwara Noriko、Ayaki Takashi、Maki Takakuni、Warita Hitoshi、Aoki Masashi、Tomonaga Keizo、Takahashi Ryosuke、Urushitani Makoto
    • Journal Title

      Molecular Therapy - Methods & Clinical Development

      Volume: 28 Pages: 312-329

    • DOI

      10.1016/j.omtm.2023.01.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06853, KAKENHI-PROJECT-21K07053, KAKENHI-PROJECT-23K24211, KAKENHI-PROJECT-20H05682
  • [Presentation] Transplantation of hypoxia-preconditioned oligodendrocyte precursor cells for ischemic stroke2024

    • Author(s)
      桑田 康弘, 安田 謙, 高山 直樹, 戸田 真太郎, 綾木 孝 , 高橋 良輔, 眞木 崇州
    • Organizer
      第65回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K06853
  • [Presentation] Heterogeneity of oligodendrocyte precursor cells in health and disease2023

    • Author(s)
      眞木崇州
    • Organizer
      US-Japan Joint Workshop on the Neurovascular Unit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06853
  • [Presentation] 脳梗塞におけるオリゴデンドロサイト前駆細胞の役割2021

    • Author(s)
      眞木崇州
    • Organizer
      第139回 日本薬理学会近畿部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06853
  • [Presentation] 脳梗塞後のオリゴデンドロサイト系統細胞の形質変化2021

    • Author(s)
      眞木崇州
    • Organizer
      STROKE2021
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06853
  • [Presentation] オリゴデンドロサイトにおけるアミロイド前駆タンパク由来のアミロイド産生経路と非産生経路2018

    • Author(s)
      眞木崇州、飛田弥咲、浅田めぐみ、高橋良輔、木下彩栄
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K07056
  • [Presentation] ペリサイト、オリゴデンドロサイト前駆細胞、血管内皮細胞間の相互作用に対するアミロイドβの病的意義2018

    • Author(s)
      豊川 勝、眞木崇州、浅田めぐみ、梶 誠兒、田代善崇、高橋良輔、木下彩栄
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K07056
  • [Presentation] γ-secretase inhibitor suppresses amyloid-β production from oligodendrocyte lineage cells and inhibits maturation of oligodendrocyte precursor cells.2017

    • Author(s)
      飛田弥咲、眞木崇州、浅田めぐみ、高橋良輔、木下彩栄
    • Organizer
      日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K07056
  • [Presentation] The pathogenic roles of amyloid-β on interactions among pericytes, oligodendrocyte precursor cells, and endothelial cells2017

    • Author(s)
      豊川勝、眞木崇州、浅田めぐみ、梶誠兒、田代善崇、高橋良輔、木下彩栄
    • Organizer
      日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K07056
  • [Presentation] Oligodendrocytes and oligodendrocyte precursor cells produce amyloid-β and express different isoforms of amyloid precursor protein.2017

    • Author(s)
      飛田弥咲、眞木崇州、浅田めぐみ、高橋良輔、木下彩栄
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16K07056
  • [Presentation] The pathogenic roles of amyloid-β on interactions among pericytes, oligodendrocyte precursor cells, and endothelial cells2017

    • Author(s)
      豊川勝、眞木崇州、浅田めぐみ、梶誠兒、田代善崇、高橋良輔、木下彩栄
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16K07056

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