Kise Yoshiaki 木瀬孔明

Researcher Number	70769611
Affiliation (Current)	2023: 東京大学, 大学院理学系研究科(理学部), 特任准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京大学, 大学院理学系研究科(理学部), 特任准教授 2016 – 2020: 東京大学, 大学院理学系研究科(理学部), 特任助教
Review Section/Research Field	Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 43020:Structural biochemistry-related / Basic Section 44010:Cell biology-related / Cell biology Except Principal Investigator Developmental biology
Keywords	Principal Investigator イオンチャネル / シグナル伝達 / 軸索 / リポソーム / 自己交叉忌避 / 樹状突起 / 分枝 / 軸索分枝 Except Principal Investigator リン酸化酵素 / 維持 … More / 自己組織化 / 老化 / 神経回路 / 時空間制御 / 受容体 / 細胞内シグナル伝達 / シナプス / 空間配置 / 軸索 / 感覚ニューロン / タイリング / 受容領域 / 樹状突起 / ショウジョウバエ Less

イオンチャネル巨大複合体のモジュレーション機構Principal Investigator
- Principal Investigator
  
  木瀬孔明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokyo
新規リポソーム再構成法による膜電位、膜張力依存的イオンチャネルの作動機構の解明Principal Investigator
- Principal Investigator
  
  木瀬孔明
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Molecular mechanisms of neurite self-avoidancePrincipal Investigator
- Principal Investigator
  
  Kise Yoshiaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokyo
Mechanisms of axon collateral formation by cell-intrinsic Dscam1-Dscam1 interactionsPrincipal Investigator
- Principal Investigator
  
  Kise Yoshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
Molecular and cellular basis for dendritic development and maintenance
- Principal Investigator
  
  Emoto Kazuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Developmental biology
- Research Institution
  The University of Tokyo

All 2021 2019 2018 2016

All Journal Article Presentation

[Journal Article] Structural basis of gating modulation of Kv4 channel complexes.2021
- Author(s)
  Kise Y, Kasuya G, Okamoto HH, Yamanouchi D, Kobayashi K, Kusakizako T, Nishizawa T, Nakajo K, Nureki O.
- Journal Title
  
  Nature
  
  Volume: 599 Issue: 7883 Pages: 158-164
- DOI
  10.1038/s41586-021-03935-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06207, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-21K06786, KAKENHI-PROJECT-20K15754, KAKENHI-PROJECT-22KJ0604
[Journal Article] Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed2021
- Author(s)
  Izadifar A, Courchet J, Virga DM, Verreet T, Hamilton S, Ayaz D, Misbaer A, Vandenbogaerde S, Monteiro L, Petrovic M, Sachse S, Yan B, Erfurth ML, Dascenco D, Kise Y, Yan J, Edwards-Faret G, Lewis T, Polleux F, Schmucker D.
- Journal Title
  
  Neuron
  
  Volume: 109 Issue: 18 Pages: 2864-2883
- DOI
  10.1016/j.neuron.2021.07.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06207
[Journal Article] Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation.2019
- Author(s)
  Sachse SM, Lievens S, Ribeiro LF, Dascenco D, Masschaele D, Horre K, Misbaer A, Vanderroost N, De Smet AS, Salta E, Erfurth ML, Kise Y, Nebel S, Van Delm W, Plaisance S, Tavernier J, De Strooper B, De Wit J, Schmucker D.
- Journal Title
  
  EMBO J
  
  Volume: 38 Issue: 6
- DOI
  10.15252/embj.201899669
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06207, KAKENHI-PROJECT-16K18536
[Presentation] Structural basis of gating modulation of the Kv4 macromolecular channel complex2021
- Author(s)
  Yoshiaki Kise
- Organizer
  生理研研究会「構造情報を基盤とした膜機能分子の生理機能理解に向けて」
- Invited
- Data Source
  KAKENHI-PROJECT-18K06207
[Presentation] Molecular signaling pathways regulating axon branching via Dscam12019
- Author(s)
  Kise Y, Izadifar A, Schmucker D, Emoto K
- Organizer
  The 41st Annual Meeting of the Japan Neuroscience Society in 2018 at Kobe
- Data Source
  KAKENHI-PROJECT-18K06207
[Presentation] Wnk regulates Nmnat and Axundead during axon morphogenesis and maintenance2019
- Author(s)
  Izadifar A., Courchet J., Verreet T., Ayaz D., Petrovic M., Sachse S. Misbaer A., Vandenbogaerde S., Yan B., Erfurth ML, Dascenco D., Kise Y., Yan J., Lewis T., Polleux F., Schmucker D.
- Organizer
  3rd Axon Meeting "Circuits Development & Axon Regeneration" at Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06207
[Presentation] Molecular signaling pathways regulating axon branching via Dscam12018
- Author(s)
  Kise Y, Izadifar A, Schmucker D, Emoto K
- Organizer
  The 41st Annual Meeting of the Japan Neuroscience Society in 2018 at Kobe
- Data Source
  KAKENHI-PROJECT-16K18536
[Presentation] Studying diversity and functions of clustered protocadherins in Xenopus tropicalis2016
- Author(s)
  Zengjin Huang, Yoshiaki Kise, Changsheng Chen, Sun Wei, Emre Etlioglu, Maximilian Ulbrich, Wei Chen, Dietmar Schmucker
- Organizer
  Cold Spring Harbor Laboratory Meeting on Axon guidance, Synapse formation & Regeneration
- Place of Presentation
  Cold Spring Harbor (the USA)
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18536

1. Emoto Kazuo (80300953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 冨樫和也 (40450613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 古泉博之 (10334335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Dietmar Schmucker

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Kise Yoshiaki 木瀬 孔明

Research Projects

Research Products

Co-Researchers

イオンチャネル巨大複合体のモジュレーション機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規リポソーム再構成法による膜電位、膜張力依存的イオンチャネルの作動機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of neurite self-avoidancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of axon collateral formation by cell-intrinsic Dscam1-Dscam1 interactionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular and cellular basis for dendritic development and maintenance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structural basis of gating modulation of Kv4 channel complexes.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Structural basis of gating modulation of the Kv4 macromolecular channel complex2021

Author(s)

Organizer

Data Source

[Presentation] Molecular signaling pathways regulating axon branching via Dscam12019

Author(s)

Organizer

Data Source

[Presentation] Wnk regulates Nmnat and Axundead during axon morphogenesis and maintenance2019

Author(s)

Organizer

Data Source

[Presentation] Molecular signaling pathways regulating axon branching via Dscam12018

Author(s)

Organizer

Data Source

[Presentation] Studying diversity and functions of clustered protocadherins in Xenopus tropicalis2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Kise Yoshiaki 木瀬孔明