Yohei YOKOBAYASHI 横林洋平

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Yokobayashi Yohei 横林洋平

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Researcher Number	70769752
Other IDs
Affiliation (Current)	2025: 沖縄科学技術大学院大学, 核酸化学・工学ユニット, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 沖縄科学技術大学院大学, 核酸化学・工学ユニット, 教授 2018 – 2020: 沖縄科学技術大学院大学, 核酸化学・工学ユニット, 准教授
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Basic Section 37030:Chemical biology-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator リボザイム / RNA / 核酸化学 / 進化工学 / 合成生物学 / SELEX / Directed evolution / In vitro evolution / Ribozyme / 核酸酵素 … More / リポソーム / アプタマー / バイオセンサー / RNA工学 / リボスイッチ / 人工細胞 Less

Directed evolution of ribozymes with novel catalytic functionsPrincipal Investigator
- Principal Investigator
  
  横林洋平
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Directed Evolution of Nucleic Acid Enzymes Combining Experiment and ComputationPrincipal Investigator
- Principal Investigator
  
  Yokobayashi Yohei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Intelligent Artificial Cells that Respond to HistaminePrincipal Investigator
- Principal Investigator
  
  Yokobayashi Yohei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Okinawa Institute of Science and Technology Graduate University

All 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] High-throughput screening of cell-free riboswitches by fluorescence-activated droplet sorting2022
- Author(s)
  Tabuchi Takeshi、Yokobayashi Yohei
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 6 Pages: 3535-3550
- DOI
  10.1093/nar/gkac152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02855
[Journal Article] Directed evolution of orthogonal RNA-RBP pairs through library-vs-library in vitro selection2022
- Author(s)
  Keisuke Fukunaga and Yohei Yokobayashi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 2 Pages: 601-616
- DOI
  10.1093/nar/gkab527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15701, KAKENHI-PROJECT-19H02855
[Journal Article] Circularly-Permuted Pistol Ribozyme: A Synthetic Ribozyme Scaffold for Mammalian Riboswitches2021
- Author(s)
  Mustafina Kamila、Nomura Yoko、Rotrattanadumrong Rachapun、Yokobayashi Yohei
- Journal Title
  
  ACS Synthetic Biology
  
  Volume: 10 Issue: 8 Pages: 2040-2048
- DOI
  10.1021/acssynbio.1c00213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02855
[Journal Article] セルフリーシステムにおける人工リボスイッチの構築2020
- Author(s)
  横林　洋平
- Journal Title
  
  生物工学
  
  Volume: 98 Pages: 655-658
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19944
[Journal Article] High-Throughput Analysis and Engineering of Ribozymes and Deoxyribozymes by Sequencing2020
- Author(s)
  Yokobayashi Yohei
- Journal Title
  
  Accounts of Chemical Research
  
  Volume: 53 Issue: 12 Pages: 2903-2912
- DOI
  10.1021/acs.accounts.0c00546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02855
[Journal Article] Design of Mammalian ON-Riboswitches Based on Tandemly Fused Aptamer and Ribozyme2020
- Author(s)
  Kamila Mustafina, Keisuke Fukunaga, and Yohei Yokobayashi
- Journal Title
  
  ACS Synthetic Biology
  
  Volume: 9 Issue: 1 Pages: 19-25
- DOI
  10.1021/acssynbio.9b00371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15701, KAKENHI-PROJECT-19H02855
[Journal Article] Self-powered RNA nanomachine driven by metastable structure2019
- Author(s)
  Kobori Shungo、Nomura Yoko、Yokobayashi Yohei
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 11 Pages: 6007-6014
- DOI
  10.1093/nar/gkz364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19944, KAKENHI-PROJECT-19H02855
[Journal Article] Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles2019
- Author(s)
  Nomura Yoko、Yokobayashi Yohei
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 17 Pages: 8950-8960
- DOI
  10.1093/nar/gkz729
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19944, KAKENHI-PROJECT-19H02855
[Journal Article] Programmable Artificial Cells Using Histamine-Responsive Synthetic Riboswitch2019
- Author(s)
  Dwidar Mohammed、Seike Yusuke、Kobori Shungo、Whitaker Charles、Matsuura Tomoaki、Yokobayashi Yohei
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Issue: 28 Pages: 11103-11114
- DOI
  10.1021/jacs.9b03300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19944, KAKENHI-PROJECT-17H00888
[Journal Article] Development of a histamine aptasensor for food safety monitoring2019
- Author(s)
  Dwidar Mohammed、Yokobayashi Yohei
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 16659-16659
- DOI
  10.1038/s41598-019-52876-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19944
[Patent] AN RNA APTAMER THAT SPECIFICALLY BINDS HISTAMINE2020
- Inventor(s)
  Yokobayashi Y, Dwidar M
- Industrial Property Rights Holder
  Yokobayashi Y, Dwidar M
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19944
[Presentation] Conditional Transgene Expression Triggered By Specific mRNA Sequence2023
- Author(s)
  Selles Vidal, Lara; Suzuki, Mayumi; Yokobayashi, Yohei
- Organizer
  2023 Synthetic Biology: Engineering, Evolution & Design (SEED)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21F20810
[Presentation] High-throughput analysis of ribozyme sequence-function relationship2022
- Author(s)
  Yohei Yokobayashi
- Organizer
  RIKEN BDR Symposium 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02855
[Presentation] セルフリーシステムにおける人工リボスイッチの構築2020
- Author(s)
  横林　洋平
- Organizer
  生物工学Webシンポジウム2020
- Invited
- Data Source
  KAKENHI-PROJECT-18K19944
[Presentation] セルフリーシステムにおける人工リボスイッチの構築2020
- Author(s)
  横林　洋平
- Organizer
  生物工学Webシンポジウム2020
- Invited
- Data Source
  KAKENHI-PROJECT-19H02855
[Presentation] Expanding Chemical Interface of Artificial Cells by Synthetic Riboswitch2019
- Author(s)
  Yokobayashi Y, Dwidar M, Seike Y, Kobori S, Whitaker C, Matsuura T
- Organizer
  Cell Free Systems Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19944
[Presentation] 人工細胞でも使える（？）RNAデバイスの作成2019
- Author(s)
  横林　洋平
- Organizer
  「細胞を創る」研究会12.0
- Invited
- Data Source
  KAKENHI-PROJECT-19H02855
[Presentation] Designing RNA Devices in Test Tubes and Cells2019
- Author(s)
  Yokobayashi Y
- Organizer
  46th International Symposium on Nucleic Acids Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19944
[Presentation] Systematic Minimization of RNA Ligase Ribozyme Through Large-Scale Design-Synthesis-Sequence Cycles2019
- Author(s)
  Nomura Y, Yokobayashi Y.
- Organizer
  46th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19944
[Presentation] 人工細胞でも使える（？）RNAデバイスの作成2019
- Author(s)
  横林　洋平
- Organizer
  「細胞を創る」研究会12.0
- Invited
- Data Source
  KAKENHI-PROJECT-18K19944
[Presentation] Systematic Minimization of RNA Ligase Ribozyme Through Large-Scale Design-Synthesis-Sequence Cycles2019
- Author(s)
  Nomura Y, Yokobayashi Y.
- Organizer
  46th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02855
[Presentation] Design of Mammalian ON-riboswitches Based on Tandemly Fused Aptamer and Ribozyme2019
- Author(s)
  Mustafina k, Fukunaga K, Yokobayashi Y.
- Organizer
  46th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02855
[Presentation] Designing RNA Devices in Test Tubes and Cells2019
- Author(s)
  Yokobayashi Y.
- Organizer
  46th International Symposium on Nucleic Acids Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02855
[Presentation] High-Throughput Screening of Cell-Free Riboswitches by Droplet Sorting2019
- Author(s)
  Tabuchi T, Yokobayashi Y.
- Organizer
  Cell Free Systems Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19944

1. SELLES VIDAL LARA

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 福永圭佑

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yohei YOKOBAYASHI 横林 洋平

Yokobayashi Yohei 横林 洋平

Research Projects

Research Products

Co-Researchers

Directed evolution of ribozymes with novel catalytic functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Directed Evolution of Nucleic Acid Enzymes Combining Experiment and ComputationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intelligent Artificial Cells that Respond to HistaminePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] High-throughput screening of cell-free riboswitches by fluorescence-activated droplet sorting2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Directed evolution of orthogonal RNA-RBP pairs through library-vs-library in vitro selection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circularly-Permuted Pistol Ribozyme: A Synthetic Ribozyme Scaffold for Mammalian Riboswitches2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] セルフリーシステムにおける人工リボスイッチの構築2020

Author(s)

Journal Title

Data Source

[Journal Article] High-Throughput Analysis and Engineering of Ribozymes and Deoxyribozymes by Sequencing2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Design of Mammalian ON-Riboswitches Based on Tandemly Fused Aptamer and Ribozyme2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Self-powered RNA nanomachine driven by metastable structure2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Programmable Artificial Cells Using Histamine-Responsive Synthetic Riboswitch2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a histamine aptasensor for food safety monitoring2019

Author(s)

Journal Title

DOI

Data Source

[Patent] AN RNA APTAMER THAT SPECIFICALLY BINDS HISTAMINE2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Conditional Transgene Expression Triggered By Specific mRNA Sequence2023

Author(s)

Yohei YOKOBAYASHI 横林洋平

Yokobayashi Yohei 横林洋平