Kinugasa Hideaki 衣笠秀明

Researcher Number	70774800
Affiliation (Current)	2025: 岡山大学, 医療開発領域, 助教
Affiliation (based on the past Project Information) *help	2018 – 2023: 岡山大学, 大学病院, 助教 2016 – 2017: 岡山大学, 医学部, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator リキッドバイオプシー / ctDNA / 炎症性腸疾患関連腫瘍 / Liquid biopsy / 消化管腫瘍 / 次世代内視鏡診療 / オルガノイド / 人工知能 / 大腸癌 / Colitic cancer … More / IBD / フソバクテリウム / IBD関連腫瘍 / liquid biopsy / cfDNA / Liquid Biopsy / トランスレーショナルリサーチ / Circulating tumor DNA / 胆嚢癌 / 胆汁 Less

Next-generation endoscopic system using liquid biopsy and multimodality artificial intelligencePrincipal Investigator
- Principal Investigator
  
  衣笠秀明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Okayama University
Development of a non-invasive nucleic acid mutation detection technique for inflammatory bowel disease-associated neoplasiaPrincipal Investigator
- Principal Investigator
  
  Kinugasa Hideaki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Okayama University
The development of non-invasive method for the molecular diagnosisPrincipal Investigator
- Principal Investigator
  
  Kinugasa Hideaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Okayama University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 胆と膵2022
- Author(s)
  衣笠秀明, 能祖一裕, 加藤博也, 赤穂宗一郎, 岡田裕之.
- Total Pages
  5
- Publisher
  医学図書出版
- ISBN
  9784865174571
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Methylation analysis of DCC gene in saliva samples is an efficient method for non-invasive detection of superficial hypopharyngeal cancer2024
- Author(s)
  Hirai R, Kinugasa H, Yamamoto S, Ako S, Tsutsumi K, Abe M, Miyahara K, Nakagawa M, Otsuka M
- Journal Title
  
  Br J Cancer
  
  Volume: - Issue: 10 Pages: 1725-1731
- DOI
  10.1038/s41416-024-02654-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07462, KAKENHI-PROJECT-20K17051
[Journal Article] The diagnostic ability to classify neoplasias occurring in inflammatory bowel disease by artificial intelligence and endoscopists -pilot study.2022
- Author(s)
  Yamamoto S, Kinugasa H, Hamada K, Tomiya M, Tanimoto T, Ohto A, Toda A, Takei D, Matsubara M, Suzuki S, Inoue K, Tanaka T, Hiraoka S, Okada H, Kawahara Y.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 37 Issue: 8 Pages: 1610-1616
- DOI
  10.1111/jgh.15904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] The Impact of KRAS Mutation in Patients With Sporadic Nonampullary Duodenal Epithelial Tumors.2021
- Author(s)
  Kinugasa H, Kanzaki H, Tanaka T, Yamamoto S, Yamasaki Y, Nouso K, Ichimura K, Nakagawa M, Mitsuhashi T, Okada H.
- Journal Title
  
  Clin Transl Gastroenterol.
  
  Volume: 12 Issue: 11 Pages: e00424-e00424
- DOI
  10.14309/ctg.0000000000000424
- NAID
  120007175410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Circulating tumor DNA dynamics analysis in a xenograft mouse model with esophageal squamous cell carcinoma.2021
- Author(s)
  Terasawa H, Kinugasa H, Nouso K, Yamamoto S, Hirai M, Tanaka T, Takaki A, Okada H.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 27 Issue: 41 Pages: 7134-7143
- DOI
  10.3748/wjg.v27.i41.7134
- NAID
  120007182082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Evaluation of Local Recurrence of Pancreatic Cancer by KRAS Mutation Analysis Using Washes from Endoscopic Ultrasound-Guided Fine-Needle Aspiration.2020
- Author(s)
  Matsumoto K, Kato H, Nouso K, Ako S, Kinugasa H, Horiguchi S, Saragai Y, Takada S, Yabe S, Muro S, Uchida D, Tomoda T, Okada H.
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: － Issue: 10 Pages: 2907-2913
- DOI
  10.1007/s10620-019-06006-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Human Telomerase Reverse Transcriptase Gene Promoter Mutation in Serum of Patients with Hepatocellular Carcinoma.2020
- Author(s)
  Ako S, Nouso K, Kinugasa H, Matsushita H, Terasawa H, Adachi T, Wada N, Takeuchi Y, Mandai M, Onishi H, Ikeda F, Shiraha H, Takaki A, Fujioka S, Mimura T, Okada H.
- Journal Title
  
  Oncology
  
  Volume: － Issue: 5 Pages: 311-317
- DOI
  10.1159/000506135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Liquid biopsy for patients with IBD-associated neoplasia.2020
- Author(s)
  Kinugasa H, Hiraoka S, Nouso K, Yamamoto S, Hirai M, Terasawa H, Yasutomi E, Oka S, Ohmori M, Yamasaki Y, Inokuchi T, Takahara M, Harada K, Tanaka T, Okada H
- Journal Title
  
  BMC Cancer
  
  Volume: － Issue: 1
- DOI
  10.1186/s12885-020-07699-z
- NAID
  120006951264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Factors Predicting a Favorable Disease Course Without Anti-TNF Therapy in Crohn’s Disease Patients2020
- Author(s)
  Inokuchi T, Hiraoka S, Yasutomi E, Oka S, Yamasaki Y, Kinugasa H, Takahara M, Kawano S, Harada K, Okada H, Kato J.
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 74 Issue: 4 Pages: 265-274
- DOI
  10.18926/AMO/60363
- NAID
  120006880202
- URL
  https://ousar.lib.okayama-u.ac.jp/60363
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA.2020
- Author(s)
  Hirai M, Kinugasa H, Nouso K, Yamamoto S, Terasawa H, Onishi Y, Oyama A, Adachi T, Wada N, Sakata M, Yasunaka T, Onishi H, Shiraha H, Takaki A, Okada H.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: － Issue: 4 Pages: 1118-1125
- DOI
  10.1111/jgh.15227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Heterogeneous distribution of Fusobacterium nucleatum in the progression of colorectal cancer.2020
- Author(s)
  Yamamoto S, Kinugasa H, Hirai M, Terasawa H, Yasutomi E, Oka S, Ohmori M, Yamasaki Y, Inokuchi T, Harada K, Hiraoka S, Nouso K, Tanaka T, Teraishi F, Fujiwara T, Okada H
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: － Issue: 7 Pages: 1869-1876
- DOI
  10.1111/jgh.15361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation.2019
- Author(s)
  Takahara M, Takaki A, Hiraoka S, Adachi T, Shimomura Y, Matsushita H, Nguyen TTT, Koike K, Ikeda A, Takashima S, Yamasaki Y, Inokuchi T, Kinugasa H, Sugihara Y, Harada K, Eikawa S, Morita H, Udono H, Okada H.
- Journal Title
  
  Scientific reports
  
  Volume: － Issue: 1 Pages: 11934-11934
- DOI
  10.1038/s41598-019-48331-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17433, KAKENHI-PROJECT-18H04033, KAKENHI-PROJECT-17K19598
[Journal Article] Utility of liquid biopsy using urine in patients with pancreatic ductal adenocarcinoma.2019
- Author(s)
  Terasawa H, Kinugasa H, Ako S, Hirai M, Matsushita H, Uchida D, Tomoda T, Matsumoto K, Horiguchi S, Kato H, Nouso K, Okada H.
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 20(10) Issue: 10 Pages: 1348-1353
- DOI
  10.1080/15384047.2019.1638685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Switching between Three Types of Mesalazine Formulation and Sulfasalazine in Patients with Active Ulcerative Colitis Who Have Already Received High-Dose Treatment with These Agents.2019
- Author(s)
  Yasutomi E, Hiraoka S, Yamamoto S, Oka S, Hirai M, Yamasaki Y, Inokuchi T, Kinugasa H, Takahara M, Harada K, Kato J, Okada H.
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 8(12) Issue: 12 Pages: 2109-2109
- DOI
  10.3390/jcm8122109
- NAID
  120006812114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17433
[Journal Article] Liquid biopsy of bile for the molecular diagnosis of gallbladder cancer2018
- Author(s)
  Kinugasa H, Nouso K, Ako S, Dohi C, Matsushita H, Matsumoto K, Kato H, Okada H
- Journal Title
  
  Cancer biology and therapy
  
  Volume: 印刷中 Issue: 10 Pages: 934-938
- DOI
  10.1080/15384047.2018.1456604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19345, KAKENHI-PROJECT-25220206
[Presentation] 下咽頭表在癌スクリーニングにおける唾液中のDCCメチル化解析の有用性2023
- Author(s)
  平井亮佑，衣笠秀明，平岡佐規子
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-23K07462
[Presentation] 稀な消化管腫瘍 -gastric adenocarcinoma and proximal polyposis of the stomach（GAPPS）と転移性小腸悪性黒色腫2023
- Author(s)
  平井亮佑，衣笠秀明，川野誠二
- Organizer
  日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] 下咽頭表在癌スクリーニングにおける唾液中のDCCメチル化解析の有用性2023
- Author(s)
  平井亮佑，衣笠秀明，平岡佐規子
- Organizer
  第109回消化器病学会総会(ワークショップ)
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] DCC salivary methylation analysis is extremely useful for screening patients with superficial hypopharyngeal cancer2023
- Author(s)
  R. Hirai, H. Kinugasa, S. Ako, K. Tsutsumi, M. Abe, K. Miyahara, M. Nakagawa, and M. Otsuka
- Organizer
  UEGW
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07462
[Presentation] 散発性非乳頭十二指腸上皮性腫瘍の臨床病理・分子生物学的特徴と予後因子．2022
- Author(s)
  衣笠秀明，神崎洋光，岡田裕之
- Organizer
  第108回日本消化器病学会総会(ワークショップ)
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] 炎症性腸疾患関連腫瘍に対する内視鏡医とAIの診断精度比較-pilot study-2022
- Author(s)
  山本峻平，衣笠秀明，岡田裕之
- Organizer
  第108回日本消化器病学会総会(パネルディスカッション)
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] 大腸癌におけるFusobacterium nucleatumの腫瘍内不均一性と腫瘍増殖能に関する検討2021
- Author(s)
  山本峻平，衣笠秀明，岡田裕之
- Organizer
  第107回日本消化器病学会総会(シンポジウム)
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] Xenograft マウスモデルを用いた ctDNA 動態解析2021
- Author(s)
  寺澤裕之，衣笠秀明，岡田裕之
- Organizer
  第107回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] 炎症性腸疾患関連腫瘍に対するリキッドバイオプシーの可能性2020
- Author(s)
  衣笠秀明，平岡佐規子，岡田裕之
- Organizer
  第106回日本消化器病学会総会(シンポジウム)
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] circulating tumor DNA(ctDNA)におけるhTERT promoter変異をターゲットとしたリキッドバイオプシーによる進行肝細胞癌の予後予測について2020
- Author(s)
  山本峻平，衣笠秀明，岡田裕之
- Organizer
  第106回日本消化器病学会総会(シンポジウム)
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] Prediction of the prognosis of advanced hepatocellular carcinoma patients by hTERT promoter mutation in circulating tumor DNA.2019
- Author(s)
  Mami Hirai, Hideaki Kinugasa, Kazuhiro Nouso, Hiroyuki Terasawa, Shunpei Yamamoto, Atsushi Oyama, Takuya Adachi, Nozomu Wada, Masahiro Sakata, Tetsuya Yasunaka, Hideki Onishi, Hidenori Shiraha, Akinobu Takaki, Hiroyuki Okada.
- Organizer
  UEGW (Barcelona)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] Utility of liquid biopsy using urine in patients with pancreatic ductal adenocarcinoma.2019
- Author(s)
  Hiroyuki Terasawa, Hideaki Kinugasa, Kazuhiro Nouso, Soichiro Ako, Daisuke Uchida, Takeshi Tomoda, Kazuyuki Matsumoto, Shigeru Horiguchi, Hironari Kato, Hiroyuki Okada.
- Organizer
  Digestive Disease Week and the annual meeting of the American Society for Gastrointestinal Endoscopy (DDW; San Diego)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] A new insight of liquid biopsy for IBD-associated neoplasia.2019
- Author(s)
  Hideaki Kinugasa, Kazuhiro Nouso, Hiroyuki Terasawa, Mami Hirai, Shunpei Yamamoto, Shouhei Oka, Eriko Yasutomi, Yasushi Yamasaki, Toshihiro Inokuchi, Masahiro Takahara, Keita Harada, Sakiko Hiraoka, Hiroyuki Okada.
- Organizer
  UEGW (Barcelona)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17433
[Presentation] 胆嚢癌診断における胆汁Liquid biopsyの可能性2018
- Author(s)
  衣笠秀明, 能祖一裕, 岡田裕之
- Organizer
  第104回日本消化器病学会総会(シンポジウム)
- Data Source
  KAKENHI-PROJECT-16K19345
[Presentation] The development of non-invasive molecular diagnosis of gallbladder cancer by bile juice-liquid biopsy2017
- Author(s)
  Hideaki Kinugasa, Kazuhiro Nouso, Soichiro Ako, Kazuyuki Matsumoto, Hironari kato, Hiroyuki Okada
- Organizer
  UEGW
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19345
[Presentation] The development of non-invasive method for the molecular diagnosis of gallbladder cancer2017
- Author(s)
  Hideaki Kinugasa, Kazuhiro Nouso, Soichiro Ako, Kazuyuki Matsumoto, Hironari kato, Hiroyuki Okada
- Organizer
  Digestive Disease Week and the annual meeting of the American Gastroenterological Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19345
[Presentation] New Insight of Liquid Biopsy With Bile Juice in Patients With Gallbladder Cancer2016
- Author(s)
  Hideaki Kinugasa, Kazuyuki Matsumoto, Soichiro Ako, Koichiro Tsutsumi, Hironari Kato, Kazuhiro Nouso, Hiroyuki Okada
- Organizer
  DDW
- Place of Presentation
  San Diego
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19345

1. 堤康一郎 (40610910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Kinugasa Hideaki 衣笠 秀明

Research Projects

Research Products

Co-Researchers

Next-generation endoscopic system using liquid biopsy and multimodality artificial intelligencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a non-invasive nucleic acid mutation detection technique for inflammatory bowel disease-associated neoplasiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of non-invasive method for the molecular diagnosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 胆と膵2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Methylation analysis of DCC gene in saliva samples is an efficient method for non-invasive detection of superficial hypopharyngeal cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The diagnostic ability to classify neoplasias occurring in inflammatory bowel disease by artificial intelligence and endoscopists -pilot study.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Impact of KRAS Mutation in Patients With Sporadic Nonampullary Duodenal Epithelial Tumors.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Circulating tumor DNA dynamics analysis in a xenograft mouse model with esophageal squamous cell carcinoma.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Evaluation of Local Recurrence of Pancreatic Cancer by KRAS Mutation Analysis Using Washes from Endoscopic Ultrasound-Guided Fine-Needle Aspiration.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Telomerase Reverse Transcriptase Gene Promoter Mutation in Serum of Patients with Hepatocellular Carcinoma.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Liquid biopsy for patients with IBD-associated neoplasia.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Factors Predicting a Favorable Disease Course Without Anti-TNF Therapy in Crohn’s Disease Patients2020

Author(s)

Journal Title

DOI

NAID

URL

Language

Data Source

[Journal Article] Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterogeneous distribution of Fusobacterium nucleatum in the progression of colorectal cancer.2020

Kinugasa Hideaki 衣笠秀明