Oonuma Kouhei 大沼耕平

… Alternative Names

大沼耕平オオヌマコウヘイ

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Researcher Number	70774876
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院農生命科学系, 助教
Affiliation (based on the past Project Information) *help	2023: 中部大学, 先端研究センター, 客員研究員 2020 – 2021: 北海道大学, 遺伝子病制御研究所, 助教 2017 – 2019: 甲南大学, 理工学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Developmental biology
Keywords	Principal Investigator ホヤ幼生 / 細胞系譜 / 脳 / 発生メカニズム / 神経細胞 / ホヤ / 分化 / 脳神経細胞 / 動態 / 左右非対称性 … More / 遺伝子発現制御ネットワーク / 遺伝子発現制御 / 左右非対称 / Kaede / 脳胞 / 神経回路 Less

Research Projects
(3 results)
Research Products
(33 results)

Studies on the differentiation and dynamics of neurons in the "normal" developing brain of the Ciona larva based on cell lineage analysisPrincipal Investigator
- Principal Investigator
  
  大沼耕平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Chubu University
Studies on the developmental mechanisms of neurons in the left-right asymmetric brain of the Ciona larva with the single cell resolutionPrincipal Investigator
- Principal Investigator
  
  Oonuma Kouhei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Hokkaido University
  Konan University
Studies on the neural network generating the programed behavioral change through the development of Ciona larva based on analysis of the cell lineage of the brainPrincipal Investigator
- Principal Investigator
  
  Oonuma Kouhei
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Konan University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] The complete cell lineage and MAPK- and Otx-dependent specification of the dopaminergic cells in the Ciona brain2021
- Author(s)
  Kouhei Oonuma, Takehiro G. Kusakabe
- Journal Title
  
  Development
  
  Volume: 148 Issue: 12 Pages: 1-12
- DOI
  10.1242/dev.198754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16150, KAKENHI-PROJECT-19H03213
[Journal Article] Evolution of Developmental Programs for the Midline Structures in Chordates: Insights From Gene Regulation in the Floor Plate and Hypochord Homologues of Ciona Embryos2021
- Author(s)
  Kouhei Oonuma, Maho Yamamoto, Naho Moritsugu, Nanako Okawa, Megumi Mukai, Miku Sotani, Shuto Tsunemi, Haruka Sugimoto, Eri Nakagome, Yuichi Hasegawa, Kotaro Shimai, Takeo Horie, Takehiro G. Kusakabe
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 1-12
- DOI
  10.3389/fcell.2021.704367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16150, KAKENHI-PROJECT-19H03213, KAKENHI-PLANNED-21H05239, KAKENHI-PROJECT-19H03204, KAKENHI-PROJECT-21K19249, KAKENHI-ORGANIZER-21H05238
[Journal Article] A single motor neuron determines the rhythm of early motor behavior in Ciona2021
- Author(s)
  Taichi Akahoshi, Madoka K. Utsumi, Kouhei Oonuma, Makoto Murakami, Takeo Horie, Takehiro G. Kusakabe, Kotaro Oka, Kohji Hotta
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 50 Pages: 1-12
- DOI
  10.1126/sciadv.abl6053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16150, KAKENHI-PROJECT-19H03213, KAKENHI-PLANNED-21H05239, KAKENHI-PROJECT-19H03204, KAKENHI-PROJECT-19J21665, KAKENHI-PROJECT-21K19249, KAKENHI-ORGANIZER-21H05238
[Journal Article] Spatio-temporal regulation of Rx and mitotic patterns shape the eye-cup of the photoreceptor cells in Ciona2019
- Author(s)
  Oonuma, K. and Kusakabe, T. G.
- Journal Title
  
  Developmental Biology
  
  Volume: 445 Issue: 2 Pages: 245-255
- DOI
  10.1016/j.ydbio.2018.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15130, KAKENHI-PROJECT-16H04724
[Presentation] ホヤ幼生の細胞系譜解析からひも解く脳の発生メカニズム（2023年度成茂動物科学振興賞受賞発表）2023
- Author(s)
  大沼耕平
- Organizer
  日本動物学会
- Data Source
  KAKENHI-PROJECT-23K05786
[Presentation] The complete cell lineage and MAPK- and Otx-dependent specification of the dopaminergic cells in the Ciona brain2022
- Author(s)
  大沼耕平、日下部岳広
- Organizer
  第1回NBRPホヤ主催オンラインセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] 脊索動物の正中構造の発生プログラム進化とヘッジホッグシグナルの役割2021
- Author(s)
  日下部岳広、佐藤由奈、関彩花、山本真帆、森継奈穂、大川奈菜子、曽谷実玖、圓尾綾菜、常深秀人、堀江健生、笹倉靖徳、大沼耕平
- Organizer
  日本動物学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生の脳にあるドーパミン産生細胞の発生メカニズムの解析2021
- Author(s)
  大沼耕平、日下部岳広
- Organizer
  日本動物学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生尾部神経索グリア細胞の多様性と機能2021
- Author(s)
  曽谷実玖、大川奈菜子、堀江健生、大沼耕平、日下部岳広
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] 脊索動物の正中構造の発生プログラム進化とヘッジホッグシグナルの役割2021
- Author(s)
  日下部岳広、佐藤由奈、関彩花、山本真帆、森継奈穂、大川奈菜子、曽谷実玖、圓尾綾菜、常深秀人、堀江健生、笹倉靖徳、大沼耕平
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生の脳にあるグルタミン酸作動性ニューロンの細胞系譜と発生メカニズムの解析2020
- Author(s)
  大沼耕平、日下部岳広
- Organizer
  日本動物学会第91大会2020
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] Ca2+振動する一対の運動ニューロンA10.64はホヤにおいて初期の自発的運動を制御する2020
- Author(s)
  赤星太一、大沼耕平、村上誠、堀江健生、日下部岳広、岡浩太郎、堀田耕司
- Organizer
  日本動物学会第91大会2020 関連集会第38回ホヤの生物学談話会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ神経索特異的遺伝子群の同定と発現調節機構の解析2020
- Author(s)
  曽谷実玖、大川奈菜子、山本真帆、堀江健生、大沼耕平、日下部岳広
- Organizer
  日本動物学会第91大会2020
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] 眼点レンズ細胞の細胞系譜と発生機構2020
- Author(s)
  古結大樹、緒方翼、大沼耕平、日下部岳広
- Organizer
  第5会ホヤ研究会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生脳胞の完全な細胞系譜の解明と発生機構2020
- Author(s)
  大沼耕平、日下部岳広
- Organizer
  第5会ホヤ研究会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ神経索特異的遺伝子群の同定と発現調節機構の解析2020
- Author(s)
  曽谷実玖、山本真帆、中村瑞葉、大川奈菜子、大沼耕平、日下部岳広
- Organizer
  第5会ホヤ研究会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] Mitotic patterns of photoreceptor lineage cells and the cell lineage of the coronet cells2019
- Author(s)
  Kouhei Oonuma and Takehiro G. Kusakabe
- Organizer
  The Ciona Connectome meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] Left-right asymmetric development of cells in the larval brain of Ciona2019
- Author(s)
  Kouhei Oonuma and Takehiro G. Kusakabe
- Organizer
  10th International Tunicate Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ胚のフロアプレートと内胚葉索にみられる遺伝子発現調節機構の共通性2019
- Author(s)
  山本真帆、森継奈穂、常深秀人、大川奈菜子、堀江健生、大沼耕平、日下部岳広
- Organizer
  日本動物学会　第90回大阪大会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ胚のフロアプレートと内胚葉索に共通な遺伝子発現調節機構の解析2019
- Author(s)
  山本真帆、森継奈穂、常深秀人、堀江健生、大沼耕平、日下部岳広
- Organizer
  2019年度日本動物学会近畿支部春季研究発表会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] Evolution of developmental programs for the midline structure in chordates: insights from gene regulation in the floor plate and hypo chord homologues of Ciona embryos2019
- Author(s)
  Shuto Tsunami, Naho Moritsugu, Kouhei Oonuma, Mike Levine, Takeo Horie and Takehiro G. Kusakabe
- Organizer
  10th International Tunicate Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生眼点のレンズ特異的分子マーカーの同定とレンズ細胞の発生機構の解析2019
- Author(s)
  緒方翼、佐藤南美、大沼耕平、日下部岳広
- Organizer
  第42回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生の脳にあるドーパミン産生細胞の細胞系譜の完全解明2019
- Author(s)
  大沼耕平、日下部岳広
- Organizer
  日本動物学会　第90回大阪大会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] 脊索動物胚の中軸構造の発生を制御する遺伝子プログラムの進化:フロアプレートとハイポコードの遺伝子発現調節機構の共通性2019
- Author(s)
  山本真帆、森継奈穂、常深秀人、大川奈菜子、堀江健生、大沼耕平、日下部岳広
- Organizer
  第42回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K16150
[Presentation] ホヤ幼生の遊泳運動制御に関わる神経細胞分化におけるSox1/2/3 の役割2018
- Author(s)
  和田聖矢, 大沼耕平, 舟越正憲, 堀江健生, 島井光太郎, 日下部岳広
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] 胚の中軸組織に共通の遺伝子発現とヘッジホッグシグナルの役割2018
- Author(s)
  常深秀人、森継奈穂、玉井雅大、大沼耕平、日下部岳広
- Organizer
  第4回ホヤ研究会
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] 神経回路の形成とニューロンの細胞系譜2018
- Author(s)
  和田聖矢、大沼耕平、中込絵梨、原田瑞輝、日下部岳広
- Organizer
  第4回ホヤ研究会
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] ホヤ胚の胚葉間で共通の中軸組織特異的遺伝子発現とヘッジホッグシグナルの役割2018
- Author(s)
  常深秀人、森継奈穂、玉井雅大、大沼耕平、大道裕、島井光太郎、堀江健生、Michael Levine、日下部岳広
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] SoxB1はカタユウレイボヤの前尾部抑制性ニューロンの発生に重要な役割を担う2017
- Author(s)
  和田聖矢、島井光太郎、大沼耕平、舟越正憲、森口大輔、一瀬葵、西辻光希、堀江健生、日下部岳広
- Organizer
  日本動物学会第88回大会
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] SoxB1 plays a crucial role in development of the anterior caudal inhibitory neurons in the Ciona intestinalis larva2017
- Author(s)
  Seiya Wada, Kotaro Shimai, Kouhei Oonuma, Masanori Funakoshi, Daisuke Moriguchi, Aoi Ichinose, Koki Nishitsuji, Takeo Horie and Takehiro G Kusakabe
- Organizer
  9th International Tunicate Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] The cell lineage and the patterns of cell division for photoreceptor cells of the left-right asymmetric ocelli in the Ciona intestinalis larva2017
- Author(s)
  Kouhei Oonuma and Takehiro G. Kusakabe
- Organizer
  9th International Tunicate Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] Developmental shift of Rx expression from non-photoreceptor to photoreceptor lineage as a mechanism for photoreceptor cell specification in Ciona intestinalis2017
- Author(s)
  Kouhei Oonuma and Takehiro G. Kusakabe
- Organizer
  18th International Congress of Developmental Biologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15130
[Presentation] ホヤ幼生の運動制御神経回路を構成するニューロンの細胞系譜解析2017
- Author(s)
  村上誠、大沼耕平、日下部岳広
- Organizer
  ComBio2017生命科学系学会合同年次大会（第40回日本分子生物学会年会、第90回日本生化学大会　合同大会）
- Data Source
  KAKENHI-PROJECT-17K15130

Oonuma Kouhei 大沼 耕平

大沼 耕平 オオヌマ コウヘイ

Research Projects

Research Products

Studies on the differentiation and dynamics of neurons in the "normal" developing brain of the Ciona larva based on cell lineage analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the developmental mechanisms of neurons in the left-right asymmetric brain of the Ciona larva with the single cell resolutionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the neural network generating the programed behavioral change through the development of Ciona larva based on analysis of the cell lineage of the brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The complete cell lineage and MAPK- and Otx-dependent specification of the dopaminergic cells in the Ciona brain2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evolution of Developmental Programs for the Midline Structures in Chordates: Insights From Gene Regulation in the Floor Plate and Hypochord Homologues of Ciona Embryos2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A single motor neuron determines the rhythm of early motor behavior in Ciona2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatio-temporal regulation of Rx and mitotic patterns shape the eye-cup of the photoreceptor cells in Ciona2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] ホヤ幼生の細胞系譜解析からひも解く脳の発生メカニズム（2023年度 成茂動物科学振興賞 受賞発表）2023

Author(s)

Organizer

Data Source

[Presentation] The complete cell lineage and MAPK- and Otx-dependent specification of the dopaminergic cells in the Ciona brain2022

Author(s)

Organizer

Data Source

[Presentation] 脊索動物の正中構造の発生プログラム進化とヘッジホッグシグナルの役割2021

Author(s)

Organizer

Data Source

[Presentation] ホヤ幼生の脳にあるドーパミン産生細胞の発生メカニズムの解析2021

Author(s)

Organizer

Data Source

[Presentation] ホヤ幼生尾部神経索グリア細胞の多様性と機能2021

Author(s)

Organizer

Data Source

[Presentation] 脊索動物の正中構造の発生プログラム進化とヘッジホッグシグナルの役割2021

Author(s)

Organizer

Data Source

[Presentation] ホヤ幼生の脳にあるグルタミン酸作動性ニューロンの細胞系譜と 発生メカニズムの解析2020

Author(s)

Organizer

Data Source

[Presentation] Ca2+振動する一対の運動ニューロンA10.64はホヤにおいて初期の自発的運動を制御する2020

Author(s)

Organizer

Data Source

[Presentation] ホヤ神経索特異的遺伝子群の同定と発現調節機構の解析2020

Author(s)

Organizer

Data Source

[Presentation] 眼点レンズ細胞の細胞系譜と発生機構2020

Author(s)

Oonuma Kouhei 大沼耕平

大沼耕平オオヌマコウヘイ

[Presentation] ホヤ幼生の細胞系譜解析からひも解く脳の発生メカニズム（2023年度成茂動物科学振興賞受賞発表）2023

[Presentation] ホヤ幼生の脳にあるグルタミン酸作動性ニューロンの細胞系譜と発生メカニズムの解析2020

[Presentation] 脊索動物胚の中軸構造の発生を制御する遺伝子プログラムの進化:フロアプレートとハイポコードの遺伝子発現調節機構の共通性2019