KUBO Tomohiro 久保智広

… Alternative Names

久保智広クボトモヒロ

Less

Researcher Number	70778745
Other IDs	https://orcid.org/0000-0002-4341-5631
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 講師
Affiliation (based on the past Project Information) *help	2023: 山梨大学, 大学院総合研究部, 講師 2019 – 2021: 山梨大学, 大学院総合研究部, 講師 2017 – 2018: 山梨大学, 大学院総合研究部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 44040:Morphology and anatomical structure-related / Basic Section 44010:Cell biology-related / Cell biology
Keywords	Principal Investigator 繊毛 / クラミドモナス / 鞭毛内輸送系 / 鞭毛 / 鞭毛・繊毛 / ピューロマイシン / 蛋白質合成系 / 鞭毛再生 / Puromycin / kinesin-13 … More / 微小管 / SUnSET法 / カルシウム / 脱重合キネシン / カルシウムイオン / クライオ電子顕微鏡 / ポリグルタミン酸化修飾 / チューブリン翻訳後修飾 / 運動性 / TTLL / ポリグルタミン酸化 / 翻訳後修飾 / チューブリン Less

真核生物の鞭毛で新規に見つかった蛋白質合成系の解明Principal Investigator
- Principal Investigator
  
  久保智広
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  University of Yamanashi
Elucidation of calcium ion dependent flagellar assemblyPrincipal Investigator
- Principal Investigator
  
  Kubo Tomohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  University of Yamanashi
Elucidation of flagellar/ciliary assembly mechanism by tubulin polyglutamylationPrincipal Investigator
- Principal Investigator
  
  KUBO Tomohiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  University of Yamanashi

All 2023 2021 2020 2019 2018 2017 Other

All Journal Article Presentation Book Other

[Book] アグリバイオ 3月号 Vol.4, No.3, 20202020
- Author(s)
  久保智広
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-19K16123
[Book] アレルギーの臨床　１月号 Vol.40 No537, 20202020
- Author(s)
  久保智広
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-19K16123
[Book] アレルギーの臨床　5月号 Vol.40 No541, 20202020
- Author(s)
  久保智広
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-19K16123
[Book] アグリバイオ 11月号 Vol.3, No.12, 20192019
- Author(s)
  久保智広
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-19K16123
[Book] 月刊　細胞　10月号　Vol.51 No.12, 20192019
- Author(s)
  久保智広
- Publisher
  ニューサイエンス社
- ISBN
- Data Source
  KAKENHI-PROJECT-19K16123
[Journal Article] α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly2023
- Author(s)
  Kubo Tomohiro、Tani Yuma、Yanagisawa Haru-Aki、Kikkawa Masahide、Oda Toshiyuki
- Journal Title
  
  Journal of Cell Science
  
  Volume: 136 Issue: 16
- DOI
  10.1242/jcs.261070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05829, KAKENHI-PLANNED-21H05248, KAKENHI-PROJECT-21H04762, KAKENHI-PROJECT-21H02654
[Journal Article] Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a2021
- Author(s)
  Hou Yuqing、Zhao Lei、Kubo Tomohiro、Cheng Xi、McNeill Nathan、Oda Toshiyuki、Witman George B.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 134 Issue: 12 Pages: 1-11
- DOI
  10.1242/jcs.258540
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16123, KAKENHI-PROJECT-21H02654
[Journal Article] TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii2020
- Author(s)
  Picariello Tyler、Hou Yuqing、Kubo Tomohiro、McNeill Nathan A.、Yanagisawa Haru-aki、Oda Toshiyuki、Witman George B.
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 5 Pages: 1-15
- DOI
  10.1371/journal.pone.0232594
- Data Source
  KAKENHI-PROJECT-19K16123
[Journal Article] Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas2020
- Author(s)
  Craft Van De Weghe Julie、Harris J. Aaron、Kubo Tomohiro、Witman George B.、Lechtreck Karl F.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 133 Issue: 17 Pages: 1-10
- DOI
  10.1242/jcs.249805
- Data Source
  KAKENHI-PROJECT-19K16123
[Journal Article] A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1)2018
- Author(s)
  Kubo Tomohiro、Hou Yuqing、Cochran Deborah A.、Witman George B.、Oda Toshiyuki
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 29 Issue: 9 Pages: 1060-1074
- DOI
  10.1091/mbc.e17-11-0689
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15115, KAKENHI-PROJECT-17H05057
[Journal Article] Chlamydomonas as a tool to study tubulin polyglutamylation2018
- Author(s)
  Kubo Tomohiro、Oda Toshiyuki
- Journal Title
  
  Microscopy
  
  Volume: 68 Issue: 1 Pages: 80-91
- DOI
  10.1093/jmicro/dfy044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H05057, KAKENHI-PROJECT-17K15115
[Journal Article] Electrostatic interaction between polyglutamylated tubulin and the nexin?dynein regulatory complex regulates flagellar motility2017
- Author(s)
  Kubo Tomohiro、Oda Toshiyuki
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 28 Issue: 17 Pages: 2260-2266
- DOI
  10.1091/mbc.e17-05-0285
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15115, KAKENHI-PROJECT-17H05057
[Journal Article] RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly2017
- Author(s)
  Nishijima Yuya、Hagiya Yohei、Kubo Tomohiro、Takei Ryota、Katoh Yohei、Nakayama Kazuhisa
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 28 Issue: 12 Pages: 1652-1666
- DOI
  10.1091/mbc.e17-01-0017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15115, KAKENHI-PROJECT-15H04370, KAKENHI-PROJECT-15K07929
[Presentation] Distinct roles of a- and b-tubulin C-terminal tails for ciliary function as revealed by a CRISPR/Cas9 mediated gene editing in Chlamydomonas2023
- Author(s)
  Tomohiro Kubo, Yuma Tani, Haru-Aki Yanagisawa, Masahide Kikkawa, Toshiyuki Oda
- Organizer
  第49回内藤コンファレンス
- Data Source
  KAKENHI-PROJECT-23K05829
[Presentation] クラミドモナスの鞭毛内で見つかった蛋白質合成系の解明2023
- Author(s)
  久保智広
- Organizer
  第13回繊毛研究会
- Data Source
  KAKENHI-PROJECT-23K05829
[Presentation] Distinct roles of a- and b-tubulin C-terminal tails for ciliary function as revealed by a CRISPR/Cas9 mediated gene editing in Chlamydomonas2023
- Author(s)
  Tomohiro Kubo, Yuma Tani, Haru-Aki Yanagisawa, Masahide Kikkawa, Toshiyuki Oda
- Organizer
  20th International Conference on the Cell and Molecular Biology of Chlamydomonas
- Data Source
  KAKENHI-PROJECT-23K05829
[Presentation] チューブリンポリグルタミン酸化修飾による鞭毛繊毛の運動制御：αチューブリン改変株を用いた解析2021
- Author(s)
  久保智広
- Organizer
  第14回クラミドモナス研究会
- Data Source
  KAKENHI-PROJECT-19K16123
[Presentation] SUnSET法による鞭毛構築中の新規合成蛋白質のモニタリング2021
- Author(s)
  久保智広、加納夏美、小田賢幸
- Organizer
  第11回繊毛研究会
- Data Source
  KAKENHI-PROJECT-19K16123
[Presentation] 単細胞緑藻類クラミドモナスを用いた鞭毛内輸送系蛋白質IFT38の機能解析2021
- Author(s)
  久保智広, 青田海人, 高橋光規, 加納夏実, 小田賢幸
- Organizer
  第73 回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-19K16123
[Presentation] Identification of polyglutamylation sites in Chlamydomonas a-tubulin2019
- Author(s)
  Tomohiro Kubo and Toshiyuki Oda
- Organizer
  第13回クラミドモナス研究会
- Data Source
  KAKENHI-PROJECT-19K16123
[Presentation] Ca2+ signaling surpasses the suppression of flagellar assembly in the axonemal dynein-lacking mutant2019
- Author(s)
  Natsumi Kanou, Tomohiro Kubo and Toshiyuki Oda
- Organizer
  第13回クラミドモナス研究会
- Data Source
  KAKENHI-PROJECT-19K16123
[Presentation] カルシウムイオン依存的な鞭毛構築機構の解明2019
- Author(s)
  久保智広、加納夏美、小田賢幸
- Organizer
  第10回繊毛研究会
- Data Source
  KAKENHI-PROJECT-19K16123
[Presentation] A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1)2018
- Author(s)
  Kubo Tomohiro、Hou Yuqing、Cochran Deborah A.、Witman George B.、Oda Toshiyuki
- Organizer
  The 18th International Conference on the Cell and Molecular Biology of Chlamydomonas
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15115
[Presentation] A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1).2018
- Author(s)
  Tomohiro Kubo, Yuqing Hou, Deborah Cochran, George B. Witman, and Toshiyuki Oda.
- Organizer
  第70 回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-17K15115
[Presentation] IFT81とIFT74 のN末端領域はチューブリン鞭毛内輸送のメインモジュールを形成する2017
- Author(s)
  Tomohiro Kubo、Jason Brown, Karl Bellve, Branch Craige, Julie Craft, Kevin Forgarty, Karl Lechtreck, George Witman
- Organizer
  第69回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15115
[Presentation] Structural biology of Chlamydomonas flagella2017
- Author(s)
  久保智広、小田賢幸
- Organizer
  日本顕微鏡学会第73回学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15115
[]

1. 小田賢幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUBO Tomohiro 久保 智広

久保 智広 クボ トモヒロ

Research Projects

Research Products

Co-Researchers

真核生物の鞭毛で新規に見つかった蛋白質合成系の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of calcium ion dependent flagellar assemblyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of flagellar/ciliary assembly mechanism by tubulin polyglutamylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] アグリバイオ 3月号 Vol.4, No.3, 20202020

Author(s)

Publisher

ISBN

Data Source

[Book] アレルギーの臨床 １月号 Vol.40 No537, 20202020

Author(s)

Publisher

ISBN

Data Source

[Book] アレルギーの臨床 5月号 Vol.40 No541, 20202020

Author(s)

Publisher

ISBN

Data Source

[Book] アグリバイオ 11月号 Vol.3, No.12, 20192019

Author(s)

Publisher

ISBN

Data Source

[Book] 月刊 細胞 10月号 Vol.51 No.12, 20192019

Author(s)

Publisher

ISBN

Data Source

[Journal Article] α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1)2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chlamydomonas as a tool to study tubulin polyglutamylation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Electrostatic interaction between polyglutamylated tubulin and the nexin?dynein regulatory complex regulates flagellar motility2017

Author(s)

KUBO Tomohiro 久保智広

久保智広クボトモヒロ

[Book] アレルギーの臨床　１月号 Vol.40 No537, 20202020

[Book] アレルギーの臨床　5月号 Vol.40 No541, 20202020

[Book] 月刊　細胞　10月号　Vol.51 No.12, 20192019

[Presentation] クラミドモナスの鞭毛内で見つかった蛋白質合成系の解明2023