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Yoshimoto Shohei  吉本 尚平

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YOSHIMOTO SHOHEI  吉本 尚平

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Researcher Number 70780188
Other IDs
Affiliation (Current) 2025: 福岡歯科大学, 口腔歯学部, 講師
Affiliation (based on the past Project Information) *help 2020 – 2024: 福岡歯科大学, 口腔歯学部, 講師
2017 – 2019: 福岡歯科大学, 口腔歯学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 57020:Oral pathobiological science-related / Pathobiological dentistry/Dental radiology
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Basic Section 57030:Conservative dentistry-related / Basic Section 57010:Oral biological science-related / Basic Section 57020:Oral pathobiological science-related / Social dentistry
Keywords
Principal Investigator
エナメル上皮癌 / エナメル上皮腫 / エピゲノム / エナメル上皮腫癌 / 浸透圧 / 高浸透圧 / 癌微小環境 / 口腔扁平上皮癌
Except Principal Investigator
PSリポソーム / マクロファージ … More / 骨再生療法 / 分化 / 再生 / 唾液腺 / 細胞死 / オルガノイド / 根尖性歯周炎 / ケラチノサイト / リンパ節転移 / 細胞運動 / デスモソーム / Desmoglein-3 / Desmoglein-2 / Desmoglein-1 / E-cadherin / Lymph node metastasis / squamous cell carcinoma / 尿酸値 / benzbromarone / スフェロイド / アポトーシス / エナメル上皮腫 / 骨組織再生療法 / 生体活性化ガラス / ホスファチジルセリンリポソーム / 生体活性ガラス / 側方浸潤 / 浸潤 / 浸潤増殖 / 乳頭腫 / 上皮内癌 / 前癌病変 / 出血 / 酸化ストレス / 循環不全 / 異角化 / 扁平苔癬 / 扁平上皮癌 / 細胞競合 / 口腔がん / 癌 / 残存歯数 / 歯周病 / 歯周病原菌 / 大腸癌 / 胃癌 / 消化器癌 Less
  • Research Projects

    (11 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (17 People)
  •  炎症反応を応用した新規再生因子キャリアによる根尖性歯周炎の治療法開発

    • Principal Investigator
      松本 典祥
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Fukuoka Dental College
  •  エナメル上皮腫・エナメル上皮癌の顎骨吸収・骨内進展機構を標的とした制御法の検討Principal Investigator

    • Principal Investigator
      吉本 尚平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Fukuoka Dental College
  •  Induction of salivary gland organoids and establishment of a regeneration model by applying salivary gland primordium

    • Principal Investigator
      平木 昭光
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Fukuoka Dental College
  •  Study of the role of desmosome cadherin in cell motility and lymph node metastasis

    • Principal Investigator
      稲井 哲一朗
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Fukuoka Dental College
  •  Development of bone regeneration therapy by activating the RANKL reverse pathway through activation of reparative macrophages.

    • Principal Investigator
      Matsumoto Noriyoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Fukuoka Dental College
  •  Investigation of inhibitory mechanisms of ameloblastoma proliferation by benzbromarone.

    • Principal Investigator
      森田 浩光
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Fukuoka Dental College
  •  Establishment and clinical application of a novel organ regeneration method using salivary gland stem cells

    • Principal Investigator
      Hiraki Akimitsu
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Fukuoka Dental College
  •  Analysis of ameloblastic carcinoma with focus on epigenomic alterationsPrincipal Investigator

    • Principal Investigator
      Yoshimoto Shohei
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Fukuoka Dental College
  •  Cell competition at the lateral invasion front of oral squamous cell carcinoma

    • Principal Investigator
      Saku Takashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Fukuoka Dental College
  •  Multiple analysis of association between periodontitis-related bacteria and gastrointestinal cancer

    • Principal Investigator
      Hirofuji Takao
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Fukuoka Dental College
  •  Investigation of methods to suppress the oral cancer progression in a hyperosmotic conditionPrincipal Investigator

    • Principal Investigator
      YOSHIMOTO SHOHEI
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Fukuoka Dental College

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] <scp>TGF</scp>‐β3 from fibroblasts promotes necrotising sialometaplasia by suppressing salivary gland cell proliferation and inducing squamous metaplasia2024

    • Author(s)
      Yoshimoto Shohei、Yada Naomi、Ishikawa Ayataka、Kawano Kenji、Matsuo Kou、Hiraki Akimitsu、Okamura Kazuhiko
    • Journal Title

      The Journal of Pathology

      Volume: - Issue: 3 Pages: 338-346

    • DOI

      10.1002/path.6287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K09161
  • [Journal Article] IL-6 plays a critical role in stromal fibroblast RANKL induction and consequent osteoclastogenesis in ameloblastoma progression.2023

    • Author(s)
      Yoshimoto S, Morita H, Okamura K, Hiraki A, Hashimoto S.
    • Journal Title

      Laboratory Investigation

      Volume: 103 Issue: 1 Pages: 100023-100023

    • DOI

      10.1016/j.labinv.2022.100023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K10058, KAKENHI-PROJECT-20K18490
  • [Journal Article] Establishment of a novel protocol for formalin-fixed paraffin-embedded organoids and spheroids2023

    • Author(s)
      Yoshimoto Shohei、Taguchi Masahide、Sumi Satoko、Oka Kyoko、Okamura Kazuhiko
    • Journal Title

      Biology Open

      Volume: 12 Issue: 5

    • DOI

      10.1242/bio.059882

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K09161, KAKENHI-PROJECT-21K10176, KAKENHI-PROJECT-20K18490
  • [Journal Article] αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion2022

    • Author(s)
      Shohei Yoshimoto, Hiromitsu Morita, Kazuhiko Okamura, Akimitsu Hiraki, Shuichi Hashimoto
    • Journal Title

      Lab Invest

      Volume: 102(1) Issue: 1 Pages: 80-89

    • DOI

      10.1038/s41374-021-00671-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-21K10058, KAKENHI-PROJECT-20K18490
  • [Journal Article] Epipharyngeal Abrasive Therapy down-regulates the expression of Cav1.2: A key molecule in Influenza virus entry.2022

    • Author(s)
      Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, Tsunoda T, Morita H, Tanaka H, Hotta O, Yasumasu S, Hiromatsu K, Shirasawa S, Nakagawa T, Yamano T.
    • Journal Title

      In Vivo

      Volume: 36 Issue: 5 Pages: 2357-2364

    • DOI

      10.21873/invivo.12967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K10058
  • [Journal Article] Volume-regulated chloride channel regulates cell proliferation and is involved in the possible interaction between TMEM16A and LRRC8A in human metastatic oral squamous cell carcinoma cells2021

    • Author(s)
      Yoshimoto Shohei、Matsuda Miho、Kato Kenichi、Jimi Eijiro、Takeuchi Hiroshi、Nakano Shuji、Kajioka Shunichi、Matsuzaki Etsuko、Hirofuji Takao、Inoue Ryuji、Hirata Masato、Morita Hiromitsu
    • Journal Title

      European Journal of Pharmacology

      Volume: 895 Pages: 173881-173881

    • DOI

      10.1016/j.ejphar.2021.173881

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07269, KAKENHI-PROJECT-17K11645, KAKENHI-PROJECT-17K12035, KAKENHI-PROJECT-18K09510, KAKENHI-PROJECT-20H03855, KAKENHI-PROJECT-20H03854, KAKENHI-PROJECT-21K10058, KAKENHI-PROJECT-20K21681
  • [Journal Article] IDO1‐mediated Trp‐kynurenine‐AhR signal activation induces stemness and tumor dormancy in oral squamous cell carcinomas2021

    • Author(s)
      Anzai Hiromasa、Yoshimoto Shohei、Okamura Kazuhiko、Hiraki Akimitsu、Hashimoto Shuichi
    • Journal Title

      Oral Science International

      Volume: 19 Issue: 1 Pages: 31-43

    • DOI

      10.1002/osi2.1109

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18490, KAKENHI-PROJECT-17K18301, KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-21K09866
  • [Journal Article] NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment2020

    • Author(s)
      Yoshimoto Shohei、Morita Hiromitsu、Matsuda Miho、Katakura Yoshinori、Hirata Masato、Hashimoto Shuichi
    • Journal Title

      Laboratory Investigation

      Volume: 101 Issue: 1 Pages: 38-50

    • DOI

      10.1038/s41374-020-00486-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-20K18490, KAKENHI-PROJECT-20H03854, KAKENHI-PROJECT-17K11645, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17K18301, KAKENHI-PROJECT-20K21681
  • [Journal Article] Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids2020

    • Author(s)
      Yoshimoto Shohei、Yoshizumi Junko、Anzai Hiromasa、Morishita Koichiro、Okamura Kazuhiko、Hiraki Akimitsu、Hashimoto Shuichi
    • Journal Title

      Disease Models & Mechanisms

      Volume: 13 Issue: 9 Pages: 1-9

    • DOI

      10.1242/dmm.045054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-20K10129, KAKENHI-PROJECT-20K18490, KAKENHI-PROJECT-17K18301
  • [Journal Article] Keratin 17-positive Civatte bodies in oral lichen planus?distribution variety, diagnostic significance and histopathogenesis2020

    • Author(s)
      Abe Tatsuya、Kitagawa Norio、Yoshimoto Shohei、Maruyama Satoshi、Yamazaki Manabu、Inai Tetsuichiro、Hashimoto Shuichi、Saku Takashi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 14586-14586

    • DOI

      10.1038/s41598-020-71496-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10101, KAKENHI-PROJECT-17K18302, KAKENHI-PROJECT-18K09533, KAKENHI-PROJECT-18K09740
  • [Journal Article] Hypoxia‐induced HIF‐1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF‐β‐dependent EMT2019

    • Author(s)
      Shohei Yoshimoto, Fumie Tanaka, Hiromitsu Morita, Akimitsu Hiraki, Shuichi Hashimoto
    • Journal Title

      Cancer Med

      Volume: 8 Issue: 18 Pages: 7822-7832

    • DOI

      10.1002/cam4.2667

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-17K18301, KAKENHI-PROJECT-16K11713
  • [Journal Article] Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT and post-translationally repressing TGIF22018

    • Author(s)
      Tanaka Fumie、Yoshimoto Shohei、Okamura Kazuhiko、Ikebe Tetsuro、Hashimoto Shuichi
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 73 Pages: 33745-33761

    • DOI

      10.18632/oncotarget.25850

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-17K18301
  • [Presentation] ホスファチジルセリン含有リポソームと生体活性ガラスの骨形成におけるマクロファージの局在2024

    • Author(s)
      松本典祥,吉本尚平,藤政清志朗,廣瀬陽菜,金丸慎吾,松﨑英津子
    • Organizer
      日本歯科保存学会2024年度春季学術大会(第160回)
    • Data Source
      KAKENHI-PROJECT-21K09927
  • [Presentation] Three-dimensional (3D) Experimental Models in Oral Pathology2023

    • Author(s)
      Shohei Yoshimoto
    • Organizer
      The 21st International Congress of Oral Pathology and Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K09161
  • [Presentation] Three-dimensional (3D) Experimental Models in Oral Pathology2023

    • Author(s)
      Shohei Yoshimoto
    • Organizer
      The 21st International Congress of Oral Pathology and Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18490
  • [Presentation] 口腔腫瘍における腫瘍微小環境がその進展に与える影響の解析2022

    • Author(s)
      吉本尚平
    • Organizer
      第111回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K18490
  • [Presentation] 既存薬を利用した難治性口腔疾患であるエナメル上皮腫の治療薬開発2022

    • Author(s)
      吉本尚平,森田浩光
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K10058
  • [Presentation] αTAT1によるチューブリンのアセチル化はエナメル上皮腫の進展に寄与する2021

    • Author(s)
      吉本尚平,森田浩光,岡村和彦,平木昭光,橋本修一
    • Organizer
      第48回福岡歯科大学学会総会
    • Data Source
      KAKENHI-PROJECT-21K10058
  • [Presentation] Hypoxia‐induced HIF‐1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF‐β‐dependent EMT2021

    • Author(s)
      吉本尚平
    • Organizer
      第32回日本臨床口腔病理学会総会・学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K18490
  • [Presentation] HIF‐1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF‐β‐dependent EMT2020

    • Author(s)
      吉本尚平、田中文恵、森田浩光、平木昭光、橋本修一
    • Organizer
      第109回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-20K18490
  • [Presentation] Hypoxia induced HIF-1a and ZEB1 are critical for the malignant transformation of ameloblastoma2019

    • Author(s)
      吉本 尚平
    • Organizer
      第61回歯科基礎医学会総会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT2019

    • Author(s)
      吉本 尚平
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] 高浸透圧環境下におけるNFAT5による口腔扁平上皮癌の増殖促進機序2019

    • Author(s)
      吉本 尚平
    • Organizer
      第30回日本臨床口腔病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] HIF1A and ZEB1 gene expression correlate with the malignant transformation of ameloblastoma2018

    • Author(s)
      吉本 尚平
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] EMT contributes to the malignant transformation of ameloblastoma.2018

    • Author(s)
      吉本 尚平
    • Organizer
      2018IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] Peripheral ameloblastic carcinoma of the mandible with an immunohistochemical evaluation, a case report2018

    • Author(s)
      吉本 尚平
    • Organizer
      第29回日本臨床口腔病理学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] Carboxypeptidase M (CPM) expression analysis in the developing and mature mouse lung2018

    • Author(s)
      吉本 尚平
    • Organizer
      日本肺サーファクタント・界面医学会第54回学術大会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] TMEM16A and LRRC8 regulate proliferation of human tongue cancer cells.2017

    • Author(s)
      Morita H, Yoshimoto S, Nakajima M, Yoneda M, Hashimoto S, Hirofuji T, Nakamura S, Hirata M.
    • Organizer
      The 95th General Session & Exhibition of the IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K12035
  • [Presentation] NFAT5 is important for proliferation of oral squamous cell carcinoma in hyper osmotic condition2017

    • Author(s)
      吉本尚平
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] エナメル上皮癌におけるEMT誘導とCK15の発現抑制2017

    • Author(s)
      吉本尚平
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-17K18301
  • [Presentation] GPRC5A is a potential biomarker to predict the malignant transformation of ameloblastoma2017

    • Author(s)
      吉本尚平
    • Organizer
      第28回日本臨床口腔病理学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K18301
  • 1.  Hiraki Akimitsu (60404034)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  松崎 英津子 (20432924)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  Matsumoto Noriyoshi (80597948)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  森田 浩光 (30380463)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 5.  Hirofuji Takao (10189897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  Saku Takashi (40145264)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  米田 雅裕 (10253460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  谷口 奈央 (60372885)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  和田 尚久 (60380466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  北河 憲雄 (40628517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  阿部 達也 (70634856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  吉住 潤子 (40596376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  稲井 哲一朗 (00264044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  緒方 佳代子 (70830123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  大谷 崇仁 (80759738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  井上 隆司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  橋本 修一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results

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