Sakuma Ikki 佐久間一基

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SAKUMA Ikki 佐久間一基

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Researcher Number	70791721
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 特任准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 千葉大学, 大学院医学研究院, 特任准教授 2020: 千葉大学, 医学(系)研究科(研究院), 准教授 2019: 千葉大学, 大学院医学研究院, 特任助教 2017 – 2018: 千葉大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Endocrinology
Keywords	Principal Investigator 鉄代謝 / 糖尿病 / 非アルコール性脂肪性肝疾患 / インスリン抵抗性 / 非アルコール性脂肪性肝疾 / OXPHOS / 鉄 / TCA回路 / クッシング病 / 内科 / 褐色細胞腫 / ACTH

The regulatory mechanism of non-alcoholic fatty liver disease (NAFLD) through iron metabolism and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  Sakuma Ikki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Chiba University
Role of FDXR in Iron Metabolism and Glucose Metabolism in LiverPrincipal Investigator
- Principal Investigator
  
  Sakuma Ikki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Chiba University
Elucidation of the mechanism of hepatic insulin resistance via iron metabolismPrincipal Investigator
- Principal Investigator
  
  Sakuma Ikki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Chiba University
Elucidation of mechanism underlying ectopic ACTH producing pheochromocytomaPrincipal Investigator
- Principal Investigator
  
  SAKUMA Ikki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Chiba University

All 2023 2022 2021 2019 2018 2017 Other

All Journal Article Presentation Other

[Journal Article] Identification of genotype?biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency2023
- Author(s)
  Sakuma Ikki、Nagano Hidekazu、Hashimoto Naoko、Fujimoto Masanori、Nakayama Akitoshi、Fuchigami Takahiro、Taki Yuki、Matsuda Tatsuma、Akamine Hiroyuki、Kono Satomi、Kono Takashi、Yokoyama Masataka、Nishimura Motoi、Yokote Koutaro、Ogasawara Tatsuki、Fujii Yoichi、Ogawa Seishi、Lee Eunyoung、Miki Takashi、Tanaka Tomoaki
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 787-787
- DOI
  10.1038/s42003-023-05160-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17429, KAKENHI-PROJECT-22K07205, KAKENHI-PROJECT-22K08619, KAKENHI-PROJECT-23K07571, KAKENHI-PROJECT-21K08524, KAKENHI-PROJECT-22K08644, KAKENHI-PROJECT-20KK0373, KAKENHI-PROJECT-21H02974, KAKENHI-PROJECT-23K24062
[Journal Article] Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition2023
- Author(s)
  Sakuma Ikki、Gaspar Rafael C.、Luukkonen Panu K.、Kahn Mario、Zhang Dongyan、Zhang Xuchen、Murray Sue、Golla Jaya Prakash、Vatner Daniel F.、Samuel Varman T.、Petersen Kitt Falk、Shulman Gerald I.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 52
- DOI
  10.1073/pnas.2312666120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17429, KAKENHI-PROJECT-21K08524, KAKENHI-PROJECT-20KK0373
[Journal Article] Inhibition of <i>HSD17B13</i> protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis2023
- Author(s)
  Luukkonen Panu K.、Sakuma Ikki、Gaspar Rafael C.、Mooring Meghan、Nasiri Ali、Kahn Mario、Zhang Xian-Man、Zhang Dongyan、Sammalkorpi Henna、Penttil? Anne K.、Orho-Melander Marju、Arola Johanna、Juuti Anne、Zhang Xuchen、Yimlamai Dean、Yki-J?rvinen Hannele、Petersen Kitt Falk、Shulman Gerald I.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 4
- DOI
  10.1073/pnas.2217543120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0373
[Journal Article] MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway2022
- Author(s)
  Aersilan Alimasi、Hashimoto Naoko、Yamagata Kazuyuki、Yokoyama Masataka、Nakayama Akitoshi、Shi Xiaoyan、Nagano Hidekazu、Sakuma Ikki、Nohata Nijiro、Kinoshita Takashi、Seki Naohiko、Rahmutulla Bahityar、Kaneda Atsushi、Zhahara Siti Nurul、Gong Yingbo、Nishimura Motoi、Kawauchi Shoichiro、Kawakami Eiryo、Tanaka Tomoaki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 18443-18443
- DOI
  10.1038/s41598-022-23205-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08524, KAKENHI-PROJECT-22K07205, KAKENHI-PROJECT-22K08644, KAKENHI-PROJECT-20KK0373, KAKENHI-PROJECT-21H02974, KAKENHI-PROJECT-20K07561, KAKENHI-PROJECT-20K08397, KAKENHI-PROJECT-21K19398
[Journal Article] Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice2022
- Author(s)
  Gaspar Rafael C.、Lyu Kun、Hubbard Brandon T.、Leitner Brooks P.、Luukkonen Panu K.、Hirabara Sandro M.、Sakuma Ikki、Nasiri Ali、Zhang Dongyan、Kahn Mario、Cline Gary W.、Pauli Jos? Rodrigo、Perry Rachel J.、Petersen Kitt F.、Shulman Gerald I.
- Journal Title
  
  Diabetologia
  
  Volume: 66 Issue: 3 Pages: 567-578
- DOI
  10.1007/s00125-022-05838-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0373
[Journal Article] Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis2022
- Author(s)
  Fujimoto Masanori、Yokoyama Masataka、Kiuchi Masahiro、Hosokawa Hiroyuki、Nakayama Akitoshi、Hashimoto Naoko、Sakuma Ikki、Nagano Hidekazu、Yamagata Kazuyuki、Kudo Fujimi、Manabe Ichiro、Lee Eunyoung、Hatano Ryo、Onodera Atsushi、Hirahara Kiyoshi、Yokote Koutaro、Miki Takashi、Nakayama Toshinori、Tanaka Tomoaki
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1-21
- DOI
  10.1038/s41467-022-33171-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08524, KAKENHI-PROJECT-22K07205, KAKENHI-PROJECT-22K08619, KAKENHI-PROJECT-22K08644, KAKENHI-PROJECT-22K15485, KAKENHI-PROJECT-20KK0373, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03692, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21H02974, KAKENHI-PROJECT-20K07561, KAKENHI-PROJECT-20K08397, KAKENHI-PROJECT-20K08583, KAKENHI-PROJECT-21K19398, KAKENHI-PROJECT-20KK0351, KAKENHI-PROJECT-23K24062, KAKENHI-PROJECT-23K24147
[Journal Article] Cyclothymic Temperament is Associated with Poor Medication Adherence and Disordered Eating in Type 2 Diabetes Patients: A Case?Control Study2021
- Author(s)
  Yamamoto Tetsuya、Sakurai Kenichi、Watanabe Masahiro、Sakuma Ikki、Kanahara Nobuhisa、Shiina Akihiro、Hasegawa Tadashi、Watanabe Hiroyuki、Iyo Masaomi、Ishibashi Ryoichi
- Journal Title
  
  Diabetes Therapy
  
  Volume: 12 Issue: 9 Pages: 2611-2624
- DOI
  10.1007/s13300-021-01121-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08524, KAKENHI-PROJECT-20KK0373
[Journal Article] Two cases of symptomatic secondary hypophysitis due to Rathke’s cleft cysts treated with glucocorticoids: long-term follow-up2021
- Author(s)
  Hanna Deguchi-Horiuchi, Hisashi Koide, Ikki Sakuma, Yue Gao, Seiichiro Higuchi, Hidekazu Nagano, Naoko Hashimoto, Kentaro Horiguchi, Yasuo Iwadate, Naoko Inoshita, Koutaro Yokote, Tomoaki Tanaka
- Journal Title
  
  Endocr J
  
  Volume: 68 Issue: 3 Pages: 269-279
- DOI
  10.1507/endocrj.EJ20-0361
- NAID
  130008006379
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08880, KAKENHI-PROJECT-20K17527, KAKENHI-PROJECT-19KK0407, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-19K17999
[Journal Article] FBPase欠損症におけるミスセンス変異の分子病態の解明2019
- Author(s)
  20．佐久間一基，姚躍, 藤本真徳, 永野秀和, 横手幸太郎, 田中知明
- Journal Title
  
  日本内分泌学会雑誌
  
  Volume: 95 Pages: 115-117
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17999
[Journal Article] Aldosterone reduction rate after saline infusion test may be a novel prediction in patients with primary aldosteronism.2019
- Author(s)
  27.Nagano H, Kono T, Saiga A, Kubota Y, Fujimoto M, Felizola S, Ishiwata K, Tamura A, Higuchi S, Sakuma I, Hashimoto N, Suzuki S, Koide H, Takeshita N, Sakamoto S, Ban T, Yokote K, Nakamura Y, Ichikawa T, Uno T, Tanaka T.
- Journal Title
  
  J Clin Endocrinol Metab.
  
  Volume: 19 Issue: 3 Pages: 319-327
- DOI
  10.1210/clinem/dgz092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-19K17999, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K17527, KAKENHI-PROJECT-19KK0407
[Journal Article] Ceritinib Aggravates Glycemic Control in Insulin-treated Patients with Diabetes and Metastatic ALK-positive Lung Cancer2019
- Author(s)
  Sakuma Ikki、Nagano Hidekazu、Yoshino Ichiro、Yokote Koutaro、Tanaka Tomoaki
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 6 Pages: 817-820
- DOI
  10.2169/internalmedicine.1870-18
- NAID
  130007614396
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-19K17999, KAKENHI-PROJECT-19H03708
[Journal Article] A case of Hashimoto’s thyroiditis with multiple drug resistance and high expression of efflux transporters.2019
- Author(s)
  Yoshida T, Nakayama A, Tamura A, Higuchi S, Sakuma I, Nagano H, Saulo J.A. Felizola, Takemoto M, Tatsuno I, Koide H, Yokote K, Tanaka T.
- Journal Title
  
  J Clin Endocrinol Metab.
  
  Volume: 105 Issue: 2 Pages: 399-406
- DOI
  10.1210/clinem/dgz073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-19K07635, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-17K09892, KAKENHI-PROJECT-20K17527, KAKENHI-PROJECT-19KK0407, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-19K17999
[Journal Article] Prednisolone-responsive Postpartum IgG4-related Hypophysitis2018
- Author(s)
  Koide H, Shiga A, Komai E, Yamato A, Fujimoto M, Tamura A, Kono T, Nakayama A, Takiguchi T, Higuchi S, Sakuma I, Nagano H, Hashimoto N, Suzuki S, Takeda Y, Shibuya M, Nishioka H, Yamada S, Inoshita N, Ishiwatari N, Horiguchi K, Yokote K, Tanaka T.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 3 Pages: 367-375
- DOI
  10.2169/internalmedicine.8446-16
- NAID
  130006329476
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-16KK0197
[Journal Article] A Unique Case of Renovascular Hypertension due to Fibromuscular Dysplasia in an Extra-renal Artery2018
- Author(s)
  Sakuma Ikki、Saito Jun、Matsuzawa Yoko、Omura Masao、Matsui Seiji、Nishikawa Tetsuo
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 18 Pages: 2689-2694
- DOI
  10.2169/internalmedicine.0023-17
- NAID
  130007484304
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-09-15
- Language
  English
- Data Source
  KAKENHI-PROJECT-17K16160
[Journal Article] p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells.2018
- Author(s)
  Nagano H, Hashimoto N, Nakayama A, Suzuki S, Miyabayashi Y, Yamato A, Higuchi S, Fujimoto M, Sakuma I, Beppu M, Yokoyama M, Suzuki Y, Sugano S, Ikeda K, Tatsuno I, Manabe I, Yokote K, Inoue S, Tanaka T.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 115 Issue: 33 Pages: 8370-8375
- DOI
  10.1073/pnas.1804243115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-17K09892, KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-17K19643, KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279
[Journal Article] CONGESTIVE HEART FAILURE SECONDARY TO A TSH-SECRETING PITUITARY ADENOMA AGGRAVATED BY TAKOTSUBO CARDIOMYOPATHY IN AN ELDERLY PATIENT2018
- Author(s)
  Sakuma Ikki、Koide Hisashi、Yoshida Tomohiko、Yamato Azusa、Fujimoto Masanori、Tamura Ai、Komai Eri、Kono Takashi、Nagano Hidekazu、Horiguchi Kentaro、Yokote Koutaro、Tanaka Tomoaki
- Journal Title
  
  AACE Clinical Case Reports
  
  Volume: 4 Issue: 2 Pages: 115-123
- DOI
  10.4158/ep171968.cr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16160
[Journal Article] Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing's disease: a case report.2017
- Author(s)
  Takiguchi T, Koide H, Nagano H, Nakayama A, Fujimoto M, Tamura A, Komai E, Shiga A, Kono T, Higuchi S, Sakuma I, Hashimoto N, Suzuki S, Miyabayashi Y, Ishiwatari N, Horiguchi K, Nakatani Y, Yokote K, Tanaka T.
- Journal Title
  
  BMC Endocr Disord.
  
  Volume: 17 Issue: 1 Pages: 54-54
- DOI
  10.1186/s12902-017-0203-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-16KK0197
[Journal Article] SEVEN FAMILIAL DYSALBUMINEMIC HYPERTHYROXINEMIA CASES IN THREE UNRELATED JAPANESE FAMILIES AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY ANALYSIS OF THE THYROXINE BINDING PROFILE.2017
- Author(s)
  Nagano H, Nakagawa Y, Ishikawa N, Watanabe H, Miyabayashi Y, Nakayama A, Fujimoto M, Komai E, Shiga A, Tamura A, Kono T, Takiguchi T, Higuchi S, Sakuma I, Hashimoto N, Suzuki S, Koide H, Yokote K, Tanaka T.
- Journal Title
  
  Endocr Pract.
  
  Volume: 23 Issue: 11 Pages: 1325-1332
- DOI
  10.4158/ep171964.or
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-16KK0197
[Presentation] アルドステロン症スクリーニングにおけるレニン測定法の違いとその影響2023
- Author(s)
  瀧由樹, 河野貴史, 照山杏子, 一城貴政, 河野聡美, 高躍, 藤本真徳, 橋本直子, 佐久間一基, 永野秀和田中知明
- Organizer
  第96回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20KK0373
[Presentation] アルドステロン症スクリーニングにおけるレニン測定法の違いとその影響2023
- Author(s)
  瀧由樹, 河野貴史, 照山杏子, 一城貴政, 河野聡美, 高躍, 藤本真徳, 橋本直子, 佐久間一基, 永野秀和田中知明
- Organizer
  第96回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08524
[Presentation] アルドステロン症スクリーニング検査における測定法の違いとその影響に関する検討2022
- Author(s)
  瀧由樹, 河野貴史, 照山杏子, 一城貴政, 河野聡美, 高躍, 藤本真徳, 橋本直子, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第23回日本内分泌学会関東甲信越支部学術集会
- Data Source
  KAKENHI-PROJECT-20KK0373
[Presentation] アルドステロン症スクリーニングにおける測定法の違いとその影響2022
- Author(s)
  瀧由樹, 河野貴史, 照山杏子, 一城貴政, 河野聡美, 高躍, 藤本真徳, 橋本直子, 佐久間一基, 永野秀和, 田中知明:
- Organizer
  第32回臨床内分泌代謝update
- Data Source
  KAKENHI-PROJECT-20KK0373
[Presentation] アルドステロン症スクリーニングにおける測定法の違いとその影響2022
- Author(s)
  瀧由樹, 河野貴史, 照山杏子, 一城貴政, 河野聡美, 高躍, 藤本真徳, 橋本直子, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第32回臨床内分泌代謝update
- Data Source
  KAKENHI-PROJECT-21K08524
[Presentation] アルドステロン症スクリーニング検査における測定法の違いとその影響に関する検討2022
- Author(s)
  瀧由樹, 河野貴史, 照山杏子, 一城貴政, 河野聡美, 高躍, 藤本真徳, 橋本直子, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第23回日本内分泌学会関東甲信越支部学術集会
- Data Source
  KAKENHI-PROJECT-21K08524
[Presentation] シングルセル解析から捉えた副腎性クッシング症候群の分子病態2021
- Author(s)
  河野聡美, 村田和貴, 藤本真徳, 中山哲俊, 樋口誠一郎, 橋本直子, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第31回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-20KK0373
[Presentation] シングルセル解析から捉えた副腎性クッシング症候群の分子病態2021
- Author(s)
  河野聡美, 村田和貴, 藤本真徳, 中山哲俊, 樋口誠一郎, 橋本直子, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第31回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-21K08524
[Presentation] クッシング症候群5例におけるオシロドロスタットの有用性の検討2021
- Author(s)
  橋本直子, 河野聡美, 河野貴史, 樋口誠一郎, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第31回臨床内分泌代謝Update2021
- Data Source
  KAKENHI-PROJECT-21K08524
[Presentation] クッシング症候群5例におけるオシロドロスタットの有用性の検討2021
- Author(s)
  橋本直子, 河野聡美, 河野貴史, 樋口誠一郎, 佐久間一基, 永野秀和, 田中知明
- Organizer
  第31回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-20KK0373
[Presentation] Characterization and Categorization Based on Genotype-Biochemical Phenotype Association in Fructose-1,6-Bisphosphatase Deficiency2019
- Author(s)
  Ikki Sakuma, Yue Yao, Masanori Fujimoto, Hidekazu Nagano, Koutaro Yokote and Tomoaki Tanaka
- Organizer
  ENDO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] FBP1ミスセンス変異によるFBPase欠損症発症メカニズムの解明2019
- Author(s)
  佐久間一基、姚躍、藤本真徳、永野秀和、横手幸太郎、田中知明
- Organizer
  92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17999
[Presentation] Characterization and Categorization Based on Genotype-Biochemical Phenotype Association in Fructose-1,6-Bisphosphatase Deficiency2019
- Author(s)
  Ikki Sakuma, Yue Yao, Masanori Fujimoto, Hidekazu Nagano, Koutaro Yokote and Tomoaki Tanaka
- Organizer
  ENDO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17999
[Presentation] FBPase欠損症における新規FBP1変異の同定と機能解析2018
- Author(s)
  佐久間一基、姚躍、藤本真徳、永野秀和、横手幸太郎、田中知明
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] p53下流遺伝子FDXRによる鉄代謝依存的ROS制御を介した肝糖新生の調節機構2018
- Author(s)
  佐久間一基、姚躍、横手幸太郎、田中知明
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] FBPase欠損症におけるミスセンス変異の分子病態の解明2018
- Author(s)
  佐久間一基、姚躍、藤本真徳、永野秀和、横手幸太郎、田中知明
- Organizer
  第28回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] FBPase欠損症の成人例で同定されたFBP1新規変異とその機能解析2017
- Author(s)
  佐久間一基、藤本真徳, 大和梓, 田村愛, 駒井絵里, 志賀明菜, 河野貴史, 中山哲俊, 永野秀和, 鈴木佐和子, 小出尚史, 田中知明, 横手幸太郎
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] 症例から学ぶ副腎性高血圧症の病理と遺伝子変異副腎静脈サンプリングで機能性を確認しえたアルドステロン産生腺腫合併の無症候性褐色細胞腫2017
- Author(s)
  佐久間一基, 山崎有人, 笹野公伸, 横手幸太郎, 田中知明
- Organizer
  第40回日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] セリチニブ投与後に血糖コントロール悪化を認めた2型糖尿病の1例2017
- Author(s)
  佐久間一基、石田晶子, 吉井聡美, 出口ハンナ, 大和梓, 藤本真徳, 田村愛, 駒井絵里, 河野貴史, 永野秀和, 小出尚史, 田中知明, 横手幸太郎
- Organizer
  第27回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-17K16160
[Presentation] FBPase欠損症の成人例で同定されたFBP1新規変異とその機能解析2017
- Author(s)
  佐久間一基, 藤本真徳、大和梓、田村愛、駒井絵里、志賀明菜、河野貴史、中山哲俊、永野秀和、鈴木佐和子、小出尚史、田中知明、横手幸太郎
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16160
[]

1. 田中知明 (50447299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 鈴木佐和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Sakuma Ikki 佐久間 一基

SAKUMA Ikki 佐久間 一基

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The regulatory mechanism of non-alcoholic fatty liver disease (NAFLD) through iron metabolism and its clinical applicationPrincipal Investigator

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Role of FDXR in Iron Metabolism and Glucose Metabolism in LiverPrincipal Investigator

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Elucidation of the mechanism of hepatic insulin resistance via iron metabolismPrincipal Investigator

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Elucidation of mechanism underlying ectopic ACTH producing pheochromocytomaPrincipal Investigator

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[Journal Article] Identification of genotype?biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency2023

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[Journal Article] Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition2023

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[Journal Article] Inhibition of <i>HSD17B13</i> protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis2023

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[Journal Article] MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway2022

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[Journal Article] Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice2022

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[Journal Article] Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis2022

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[Journal Article] Cyclothymic Temperament is Associated with Poor Medication Adherence and Disordered Eating in Type 2 Diabetes Patients: A Case?Control Study2021

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[Journal Article] Two cases of symptomatic secondary hypophysitis due to Rathke’s cleft cysts treated with glucocorticoids: long-term follow-up2021

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[Journal Article] FBPase欠損症におけるミスセンス変異の分子病態の解明2019

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[Journal Article] Aldosterone reduction rate after saline infusion test may be a novel prediction in patients with primary aldosteronism.2019

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Sakuma Ikki 佐久間一基

SAKUMA Ikki 佐久間一基