Ito Masamichi 伊藤正道

Researcher Number	70794642
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator DNA損傷 / ラミン変異 / 拡張型心筋症 / 心不全 / LMNA変異 / iPS細胞 / iPS心筋細胞 / CRISPRスクリーニング / DNA損傷応答 / 創薬 … More / iPS細胞由来心筋細胞 / iPS創薬 / 化合物スクリーニング / エピゲノム / ラミン / エピゲノム解析 / 網羅的遺伝子発現解析 / 病態解明 / 特発性拡張型心筋症 Less

CRISPRスクリーニングを用いた心筋細胞のDNA損傷応答機構の解明と心不全治療法の開発Principal Investigator
- Principal Investigator
  
  伊藤正道
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
Exploring therapeutic candidate compounds for LMNA-mutant dilated cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  Ito Maamichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
Elucidation of disease mechanism of LMNA-mutant dilated cardiomyopathy focusing on chromatin remodeling and DNA damage responsePrincipal Investigator
- Principal Investigator
  
  Ito Masamichi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] TEAD1 trapping by the Q353R?Lamin A/C causes dilated cardiomyopathy2023
- Author(s)
  Yamada S、et al.,
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 15 Pages: 1-1
- DOI
  10.1126/sciadv.ade7047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06809, KAKENHI-PROJECT-21K16082, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21K16047, KAKENHI-PROJECT-22H00471, KAKENHI-PLANNED-19H05744, KAKENHI-PLANNED-21H05254, KAKENHI-PLANNED-22H05125, KAKENHI-PROJECT-22H00320, KAKENHI-PROJECT-23K24057
[Journal Article] Functional Evaluation of Human Bioengineered Cardiac Tissue Using iPS Cells Derived from a Patient with Lamin Variant Dilated Cardiomyopathy2022
- Author(s)
  Miura K, Matsuura K, Yamasaki Itoyama Y, Sasaki D, Takada T, Furutani Y, Hayama E, Ito M, Nomura S, Morita H, Toyoda M, Umezawa A, Onoue K, Saito Y, Aburatani H, Nakanishi T, Hagiwara N, Komuro I, Shimizu T.
- Journal Title
  
  Int. Heart J.
  
  Volume: 63 Issue: 2 Pages: 338-346
- DOI
  10.1536/ihj.21-790
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2022-03-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16082, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] 循環器病領域における疾患iPS細胞の臨床応用のこれまでとこれから2022
- Author(s)
  伊藤正道
- Journal Title
  
  医学のあゆみ
  
  Volume: 283-14 Pages: 1432-1437
- Data Source
  KAKENHI-PROJECT-21K16082
[Journal Article] Fibroblast-Cardiomyocyte Interaction in Pediatric Restrictive Cardiomyopathy2021
- Author(s)
  Sato T, Ito M
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 5 Pages: 687-689
- DOI
  10.1253/circj.CJ-21-0100
- NAID
  130008028989
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-04-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17515, KAKENHI-PROJECT-21K16082
[Journal Article] Still on the Way Toward Clinical Application2021
- Author(s)
  Ito M, Morita H
- Journal Title
  
  Int. Heart J.
  
  Volume: 62 Issue: 2 Pages: 221-223
- DOI
  10.1536/ihj.21-053
- NAID
  130008007423
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2021-03-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17515, KAKENHI-PROJECT-21K16082
[Journal Article] Trends and Limitations in the Assessment of the Contractile Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Patients With Dilated Cardiomyopathy2020
- Author(s)
  Ito M, Nomura S, Morita H, Komuro I.
- Journal Title
  
  Front Cardiovasc Med.
  
  Volume: 7 Pages: 154-154
- DOI
  10.3389/fcvm.2020.00154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19K17515
[Presentation] Disease modeling and drug discovery for LMNA-mutant dilated cardiomyopathy2022
- Author(s)
  Masamichi Ito
- Organizer
  日本循環器学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16082
[Presentation] Impaired Vitamin D Signaling Causes LMNA Mutation-related Cardiomyopathy2022
- Author(s)
  Masamichi Ito
- Organizer
  日本循環器学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16082
[Presentation] Construction of a Screening System for Therapeutic Candidate Compounds for Dilated Cardiomyopathy Using iPS cell-derived Cardiomyocytes2021
- Author(s)
  Masamichi Ito Seitaro Nomura, Hiroyuki Morita, Issei Komuro
- Organizer
  第85回　日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17515
[Presentation] Exploring drug candidates for LMNA-mutant dilated cardiomyopathy2019
- Author(s)
  Masamichi Ito
- Organizer
  The 3rd JCS Council Forum on BCVR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17515

1. 野村征太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Masamichi 伊藤 正道

Research Projects

Research Products

Co-Researchers

CRISPRスクリーニングを用いた心筋細胞のDNA損傷応答機構の解明と心不全治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring therapeutic candidate compounds for LMNA-mutant dilated cardiomyopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of disease mechanism of LMNA-mutant dilated cardiomyopathy focusing on chromatin remodeling and DNA damage responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] TEAD1 trapping by the Q353R?Lamin A/C causes dilated cardiomyopathy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional Evaluation of Human Bioengineered Cardiac Tissue Using iPS Cells Derived from a Patient with Lamin Variant Dilated Cardiomyopathy2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] 循環器病領域における疾患iPS細胞の臨床応用のこれまでとこれから2022

Author(s)

Journal Title

Data Source

[Journal Article] Fibroblast-Cardiomyocyte Interaction in Pediatric Restrictive Cardiomyopathy2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Still on the Way Toward Clinical Application2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Trends and Limitations in the Assessment of the Contractile Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Patients With Dilated Cardiomyopathy2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Disease modeling and drug discovery for LMNA-mutant dilated cardiomyopathy2022

Author(s)

Organizer

Data Source

[Presentation] Impaired Vitamin D Signaling Causes LMNA Mutation-related Cardiomyopathy2022

Author(s)

Organizer

Data Source

[Presentation] Construction of a Screening System for Therapeutic Candidate Compounds for Dilated Cardiomyopathy Using iPS cell-derived Cardiomyocytes2021

Author(s)

Organizer

Data Source

[Presentation] Exploring drug candidates for LMNA-mutant dilated cardiomyopathy2019

Author(s)

Organizer

Data Source

Ito Masamichi 伊藤正道