Ogami Koichi 尾上耕一

Researcher Number	70796523
Other IDs	https://orcid.org/0000-0001-9380-9666
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 名古屋大学, 医学系研究科, 助教 2019: 名古屋市立大学, 医薬学総合研究院(薬学), 助教 2018: 名古屋市立大学, 大学院薬学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator 翻訳 / ヒストン修飾 / RNA分解 / 転写サイクル / intronic polyadenylation / RNA代謝 / RNA修飾 / がんトランスクリプトーム / ポリアデニル化 / direct RNA-seq … More / TOP mRNA / directRNA sequencing / ナノポアシークエンサー / ポリA鎖 / 遺伝子発現 / CPEB / ポリA鎖伸長 / mRNA分解 / RNA結合タンパク質 Less

Towards understanding of life cycle of prematurely terminated RNAs accumulated in cancer cellsPrincipal Investigator
- Principal Investigator
  
  尾上耕一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nagoya University
Correlation between mRNA poly(A) tail length and translational activityPrincipal Investigator
- Principal Investigator
  
  Ogami Koichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Nagoya University
CPEB-mediated post-transcriptional regulation of gene expressionPrincipal Investigator
- Principal Investigator
  
  Ogami Koichi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Nagoya City University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] リアルタイム・デジタルPCR実験スタンダード　実践編7 miRNA生合成経路をみる2022
- Author(s)
  尾上耕一，鈴木　洋
- Total Pages
  301
- Publisher
  羊土社
- ISBN
  9784758122573
- Data Source
  KAKENHI-PROJECT-20K15719
[Journal Article] Protocol for analyzing intact mRNA poly(A) tail length using nanopore direct RNA sequencing2023
- Author(s)
  Ogami Koichi、Oishi Yuka、Hoshino Shin-ichi
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 2 Pages: 102340-102340
- DOI
  10.1016/j.xpro.2023.102340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06925
[Journal Article] TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.2023
- Author(s)
  Suzuki Miho M.、Iijima Kenta、Ogami Koichi、Shinjo Keiko、Murofushi Yoshiteru、Xie Jingqi、Wang Xuebing、Kitano Yotaro、Mamiya Akira、Kibe Yuji、Nishimura Tatsunori、Ohka Fumiharu、Saito Ryuta、Sato Shinya、Kobayashi Junya、Yao Ryoji、Miyata Kanjiro、Kataoka Kazunori、Suzuki Hiroshi I.、Kondo Yutaka.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4521-4521
- DOI
  10.1038/s41467-023-40243-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20598, KAKENHI-PROJECT-19KK0209, KAKENHI-PROJECT-19K07661, KAKENHI-PROJECT-20K07570, KAKENHI-PROJECT-22K06925, KAKENHI-PROJECT-23K06610, KAKENHI-PROJECT-23K06633, KAKENHI-PROJECT-20K12162, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27438
[Journal Article] A Combinatorial Code for CPEB-Mediated c-myc Repression2023
- Author(s)
  Ogami Koichi、Ogawa Keima、Sanpei Shoko、Ichikawa Fumito、Udagawa Tsuyoshi、Hoshino Shin-ichi
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 19 Pages: 2410-2410
- DOI
  10.3390/cells12192410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06925
[Journal Article] Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis2022
- Author(s)
  Kitai Hiroki、Kato Noritoshi、Ogami Koichi、Komatsu Shintaro、Watanabe Yu、Yoshino Seiko、Koshi Eri、Tsubota Shoma、Funahashi Yoshio、Maeda Takahiro、Furuhashi Kazuhiro、Ishimoto Takuji、Kosugi Tomoki、Maruyama Shoichi、Kadomatsu Kenji、Suzuki Hiroshi I.
- Journal Title
  
  BMC Biology
  
  Volume: 20 Issue: 1 Pages: 248-248
- DOI
  10.1186/s12915-022-01447-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06925, KAKENHI-PROJECT-22K07210, KAKENHI-PROJECT-21K18251
[Journal Article] mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading2022
- Author(s)
  Ogami Koichi、Oishi Yuka、Sakamoto Kentaro、Okumura Mayu、Yamagishi Ryota、Inoue Takumi、Hibino Masaya、Nogimori Takuto、Yamaguchi Natsumi、Furutachi Kazuya、Hosoda Nao、Inagaki Hiroto、Hoshino Shin-ichi
- Journal Title
  
  Cell Reports
  
  Volume: 41 Issue: 4 Pages: 111548-111548
- DOI
  10.1016/j.celrep.2022.111548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06925
[Journal Article] Nuclear RNA Exosome and Pervasive Transcription: Dual Sculptors of Genome Function2021
- Author(s)
  Ogami Koichi、Suzuki Hiroshi I.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13401-13401
- DOI
  10.3390/ijms222413401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15719
[Journal Article] The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3’ adenylation and selective stabilization of microRNA-122.2020
- Author(s)
  Hojo, H., Yashiro1, Y., Noda1, Y., Ogami, K., Yamagishi, R., Okada, S., Hoshino, S. and Suzuki, T.
- Journal Title
  
  J Biol Chem
  
  Volume: 295 Issue: 2 Pages: 390-402
- DOI
  10.1074/jbc.ra119.011617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03635, KAKENHI-PROJECT-18K14630, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-19K22246
[Journal Article] ABCE1 acts as a positive regulator of exogenous RNA decay.2020
- Author(s)
  Nogimori, T., Ogami, K., Oishi, Y., Goda, R., Hosoda, N., Kitamura, Y., Kitade, Y., and Hoshino S.
- Journal Title
  
  viruses
  
  Volume: 20 Issue: 2 Pages: 174-174
- DOI
  10.3390/v12020174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03635, KAKENHI-PROJECT-18K14630, KAKENHI-PROJECT-19K07086
[Journal Article] Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation2020
- Author(s)
  Cheng Larry C.、Zheng Dinghai、Baljinnyam Erdene、Sun Fangzheng、Ogami Koichi、Yeung Percy Luk、Hoque Mainul、Lu Chi-Wei、Manley James L.、Tian Bin
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41467-020-16959-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15719
[Journal Article] Efficient differentiation and purification of human induced pluripotent stem cell-derived endothelial progenitor cells and expansion with the use of inhibitors of ROCK, TGF-β, and GSK3β2020
- Author(s)
  Aoki Hiromasa、Yamashita Misaki、Hashita Tadahiro、Ogami Koichi、Hoshino Shinichi、Iwao Takahiro、Matsunaga Tamihide
- Journal Title
  
  Heliyon
  
  Volume: 6 Issue: 3 Pages: e03493-e03493
- DOI
  10.1016/j.heliyon.2020.e03493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-17H03635, KAKENHI-PROJECT-18K14630, KAKENHI-PROJECT-17K08422
[Journal Article] A novel method for stabilizing microRNA mimics2019
- Author(s)
  Nogimori Takuto、Furutachi Kazuya、Ogami Koichi、Hosoda Nao、Hoshino Shin-ichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 511 Issue: 2 Pages: 422-426
- DOI
  10.1016/j.bbrc.2019.02.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14630, KAKENHI-PROJECT-17H03635, KAKENHI-PROJECT-17K19357, KAKENHI-PROJECT-19K07086
[Journal Article] RNA Surveillance by the Nuclear RNA Exosome: Mechanisms and Significance2018
- Author(s)
  Ogami Koichi、Chen Yaqiong、Manley James
- Journal Title
  
  Non-Coding RNA
  
  Volume: 4 Issue: 1 Pages: 8-8
- DOI
  10.3390/ncrna4010008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14630
[Journal Article] MicroRNP-mediated translational activation of nonadenylated mRNAs in a mammalian cell-free system2018
- Author(s)
  Wakiyama Motoaki、Ogami Koichi、Iwaoka Ryo、Aoki Kazuma、Hoshino Shin-ichi
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 5 Pages: 332-344
- DOI
  10.1111/gtc.12580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14630, KAKENHI-PROJECT-17H03635
[Journal Article] NRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells2018
- Author(s)
  Richard Patricia、Ogami Koichi、Chen Yaqiong、Feng Shuang、Moresco James J.、Yates John R.、Manley James L.
- Journal Title
  
  RNA Biology
  
  Volume: 15 Issue: 7 Pages: 868-876
- DOI
  10.1080/15476286.2018.1467180
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] Making TOP mRNA a Top Priority: Unraveling the Regulation of Protein Synthesis Machinery through Poly(A) Tail Dynamics2023
- Author(s)
  尾上耕一、星野真一
- Organizer
  第61回生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06925
[Presentation] RNAフィードバックモデルによる転写サイクル調節2022
- Author(s)
  尾上耕一、鬼丸洸、芳野聖子、鈴木洋
- Organizer
  2022年度先端モデル動物支援　若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-22K06925
[Presentation] mTOR経路不活化時におけるLARP1を介した長鎖ポリA型TOP mRNAの蓄積と意義2022
- Author(s)
  尾上耕一、星野真一
- Organizer
  第3回シロリムス新作用研究会
- Data Source
  KAKENHI-PROJECT-22K06925
[Presentation] 核内RNAレベルに呼応した転写凝集体の状態変化と転写サイクルへの影響2022
- Author(s)
  尾上耕一、鬼丸洸、芳野聖子、鈴木洋
- Organizer
  第12回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06925
[Presentation] リボソームリサイクル因子ABCE1は外来性RNA分解を正に制御する2020
- Author(s)
  尾上耕一、野木森拓人、大石結香、合田凌也、細田直、喜多村徳昭、北出幸夫、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] Poly(A) tail length positively correlates with the extent of mRNA ribosome loading2020
- Author(s)
  Koichi Ogami, Yuka Oishi, Natsumi Yamaguchi, Shin-ichi Hoshino
- Organizer
  Cold Spring Harbor Laboratory meeting: Translational Control
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] 癌抑制遺伝子産物 BTG3 による標的mRNAのポリ A 鎖制御2020
- Author(s)
  中北侑希、尾上耕一、山岸良多、細田直、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] 翻訳終結因子eRF3によるmRNAポリA鎖分解開始のメカニズム2020
- Author(s)
  宮原彰太、尾上耕一、細田直、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] mRNA3’末端ポリA鎖の長さは翻訳活性と正に相関する2020
- Author(s)
  大石結香、尾上耕一、山口奈津美、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] LARP4は呼吸鎖複合体構成因子のmRNAポリA鎖伸長を制御する2020
- Author(s)
  中村亮太、中島朋香、小林純果、志水良亮、尾上耕一、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] ウイルス感染時の細胞内翻訳シャットダウン機構の解明2020
- Author(s)
  石川裕之、尾上耕一、野木森拓人、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] RNA結合タンパク質LARP4はミトコンドリア周辺に局在する2020
- Author(s)
  中島朋香、志水良亮、尾上耕一、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] RNA3’ポリアデニル化を制御するRNA結合タンパク質の標的 miRNAの網羅的探索2020
- Author(s)
  都島大知、隠岐興一、寺山七夢、中村亮太、尾上耕一、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] インターロイキンエンハンサー結合因子ILF3は細胞質において標的mRNAのポリA鎖を伸長する2020
- Author(s)
  山口奈都美、尾上耕一、細田直、星野真一
- Organizer
  第 84 回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15719
[Presentation] LARP1はTOP mRNAのポリA鎖伸長を介してアミノ酸飢餓回復時の翻訳活性化を可能にする2019
- Author(s)
  尾上耕一、大石結香、坂元健大郎、野木森拓人、星野真一
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] RNA 結合タンパク質 LARP4 はミトコンドリア構成因子の mRNA を標的とする2019
- Author(s)
  中島朋香、尾上耕一、志水良亮、星野真一
- Organizer
  第65回薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] RNA結合タンパク質Larp1はTOP mRNAのポリA鎖伸長を介し遺伝子発現を制御する2019
- Author(s)
  大石結香、尾上耕一、星野真一
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2019
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] miRNA 医薬の新規安定化技術の開発2019
- Author(s)
  野木森拓人、古舘和也、尾上耕一、細田直、星野真一
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] インターロイキンエンハンサー結合因子３(ILF3)は標的mRNAのポリA鎖を制御する2019
- Author(s)
  山口奈津美、尾上耕一、細田直、星野真一
- Organizer
  第83回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] 新規RNA結合タンパク質Larp4Bによる標的mRNA代謝調節2018
- Author(s)
  野間崇秀、尾上耕一、細田直、山岸良多、星野真一
- Organizer
  日本病院薬剤師会東海ブロック　日本薬学会東海支部合同学術大会2018
- Data Source
  KAKENHI-PROJECT-18K14630
[Presentation] アミノ酸飢餓シグナルに呼応したLarp1によるmRNA代謝調節2018
- Author(s)
  坂元健大郎、尾上耕一、細田直、山岸良多、星野真一
- Organizer
  日本病院薬剤師会東海ブロック　日本薬学会東海支部合同学術大会2018
- Data Source
  KAKENHI-PROJECT-18K14630

1. 星野真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 細田直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 近藤豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 飯島健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 松永民秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogami Koichi 尾上 耕一

Research Projects

Research Products

Co-Researchers

Towards understanding of life cycle of prematurely terminated RNAs accumulated in cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Correlation between mRNA poly(A) tail length and translational activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CPEB-mediated post-transcriptional regulation of gene expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] リアルタイム・デジタルPCR実験スタンダード 実践編7 miRNA生合成経路をみる2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Protocol for analyzing intact mRNA poly(A) tail length using nanopore direct RNA sequencing2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Combinatorial Code for CPEB-Mediated c-myc Repression2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear RNA Exosome and Pervasive Transcription: Dual Sculptors of Genome Function2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3’ adenylation and selective stabilization of microRNA-122.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ABCE1 acts as a positive regulator of exogenous RNA decay.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient differentiation and purification of human induced pluripotent stem cell-derived endothelial progenitor cells and expansion with the use of inhibitors of ROCK, TGF-β, and GSK3β2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel method for stabilizing microRNA mimics2019

Author(s)

Ogami Koichi 尾上耕一

[Book] リアルタイム・デジタルPCR実験スタンダード　実践編7 miRNA生合成経路をみる2022